MCID: MNC001
MIFTS: 32

Monocular Esotropia

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Monocular Esotropia

MalaCards integrated aliases for Monocular Esotropia:

Name: Monocular Esotropia 12 72
Esotropia 44 72

Classifications:



External Ids:

Disease Ontology 12 DOID:10293
ICD9CM 35 378.01
MeSH 44 D004948
SNOMED-CT 68 5455000
ICD10 33 H50.01
UMLS 72 C0014877 C0152204

Summaries for Monocular Esotropia

MalaCards based summary : Monocular Esotropia, also known as esotropia, is related to accommodative esotropia and alternating esotropia. The drugs Iodine and Cholinergic Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and thyroid.

Related Diseases for Monocular Esotropia

Diseases related to Monocular Esotropia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 197)
# Related Disease Score Top Affiliating Genes
1 accommodative esotropia 12.5
2 alternating esotropia 12.4
3 blepharophimosis with ptosis, syndactyly, and short stature 12.1
4 exotropia 11.7
5 abducens nerve disease 11.5
6 hemifacial hyperplasia with strabismus 11.5
7 marshall syndrome 11.2
8 orofaciodigital syndrome iii 11.2
9 richieri-costa/guion-almeida syndrome 11.2
10 spinocerebellar ataxia, x-linked 3 11.2
11 bestrophinopathy, autosomal recessive 11.2
12 mental retardation, anterior maxillary protrusion, and strabismus 11.2
13 facial paresis, hereditary congenital, 3 11.2
14 mental retardation, autosomal recessive 36 11.2
15 strabismus 11.1
16 mechanical strabismus 11.1
17 suppression amblyopia 10.9
18 amblyopia 10.9
19 alternating exotropia 10.9
20 refractive error 10.9
21 pathologic nystagmus 10.8
22 farsightedness 10.7
23 myopia 10.7
24 anisometropia 10.6
25 astigmatism 10.4
26 ptosis 10.4
27 monofixation syndrome 10.4
28 cycloplegia 10.3
29 hypotropia 10.3
30 hypertropia 10.3
31 astrocytoma 10.2
32 cataract 10.2
33 duane retraction syndrome 1 10.2
34 down syndrome 10.2
35 accommodative spasm 10.2
36 cerebral palsy 10.2
37 supranuclear ocular palsy 10.2
38 abducens palsy 10.2
39 ocular dominance 10.2
40 hydrocephalus 10.2
41 abnormal retinal correspondence 10.2
42 papilledema 10.2
43 congenital hydrocephalus 10.2
44 polykaryocytosis inducer 10.1
45 torticollis 10.1
46 movement disease 10.1
47 eye disease 10.1
48 nervous system disease 10.1
49 congenital nystagmus 10.1
50 48,xyyy 10.1

Comorbidity relations with Monocular Esotropia via Phenotypic Disease Network (PDN):


Acute Cystitis Familial Atrial Fibrillation
Heart Disease Sinoatrial Node Disease
Third-Degree Atrioventricular Block

Graphical network of the top 20 diseases related to Monocular Esotropia:



Diseases related to Monocular Esotropia

Symptoms & Phenotypes for Monocular Esotropia

Drugs & Therapeutics for Monocular Esotropia

Drugs for Monocular Esotropia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Iodine Approved, Investigational Phase 4 7553-56-2 807
2 Cholinergic Agents Phase 4
3 Neurotransmitter Agents Phase 4
4 Autonomic Agents Phase 4
5 Micronutrients Phase 4
6 Gastrointestinal Agents Phase 4
7 Ophthalmic Solutions Phase 4
8 Cholinesterase Inhibitors Phase 4
9 Cathartics Phase 4
10 Carboxymethylcellulose Sodium Phase 4
11 Anti-Infective Agents, Local Phase 4
12 Laxatives Phase 4
13 Nutrients Phase 4
14 Trace Elements Phase 4
15
Echothiophate Iodide Phase 4 6736-03-4 10547
16 Anti-Infective Agents Phase 4
17 cadexomer iodine Phase 4
18 Pharmaceutical Solutions Phase 4
19
Acetylcholine Approved, Investigational Phase 3 51-84-3 187
20
Racepinephrine Approved Phase 2, Phase 3 329-65-7 838
21
Epinephrine Approved, Vet_approved Phase 2, Phase 3 51-43-4 5816
22
Bupivacaine Approved, Investigational Phase 2, Phase 3 2180-92-9, 38396-39-3 2474
23 Acetylcholine Release Inhibitors Phase 3
24 Botulinum Toxins Phase 3
25 Central Nervous System Depressants Phase 2, Phase 3
26 Anesthetics Phase 2, Phase 3
27 Peripheral Nervous System Agents Phase 2, Phase 3
28 abobotulinumtoxinA Phase 3
29 Neuromuscular Agents Phase 3
30 Botulinum Toxins, Type A Phase 3
31 Anesthetics, Local Phase 2, Phase 3
32 Epinephryl borate Phase 2, Phase 3
33
Lidocaine Approved, Vet_approved 137-58-6 3676
34
tannic acid Approved 1401-55-4
35
Dopamine Approved 51-61-6, 62-31-7 681
36
Methamphetamine Approved, Illicit 537-46-2 10836
37
Benzocaine Approved, Investigational 94-09-7, 1994-09-7 2337
38 Sympathomimetics
39 Adrenergic Agents
40 Central Nervous System Stimulants
41 Dopamine Agents
42 Neurotransmitter Uptake Inhibitors
43 Dopamine Uptake Inhibitors

Interventional clinical trials:

(show all 24)
# Name Status NCT ID Phase Drugs
1 Echothiophate Iodide for the Prevention of Progression of Myopia Unknown status NCT02544529 Phase 4 Echothiophate Iodide 0.03% Ophthalmic Solution;Carboxymethylcellulose Sodium (0.5%)
2 Surgery Associated to Intraoperative Botulinum Toxin A for Large Angle Horizontal Strabismus: a Pilot Study Completed NCT01460355 Phase 4 Botulinum Toxin Type A;saline solution
3 A Trial of Bifocals in Myopic Children With Esophoria Unknown status NCT00000128 Phase 3
4 The Prism Adaptation Study (PAS) Completed NCT00000121 Phase 3
5 Orthoptic Changes Following Photorefractive Keratectomy Completed NCT01279993 Phase 3
6 A Pragmatic, Randomized, Non-inferiority Trial Comparing the Effectiveness of Botulinum Toxin-based Treatment With Conventional Strabismus Surgery in Acquired Esotropia. Recruiting NCT03459092 Phase 3 Botulinum toxin type A
7 The Effect of Slanted Recession of Horizontal Muscle on Horizontal Strabismus With Abnormal Accommodative Convergence /Accommodation Ratio (AC/A) Recruiting NCT03555045 Phase 2, Phase 3
8 Bupivacaine Injection of Eye Muscles to Treat Strabismus Recruiting NCT01616108 Phase 2, Phase 3 Bupivacaine
9 Amount of Surgery for Esotropia Under Topical Anesthesia Unknown status NCT00993174
10 Prescription of Full Optical Correction in Refractive Errors to Treat Esotropia in Children up to 3 Years Old Unknown status NCT02404324
11 Long-Term Outcomes in the Treatment of Infantile and Acquired Esotropia With Botulinum Toxin Completed NCT00746304
12 Congenital Esotropia Observational Study (CEOS) Completed NCT00000163
13 A Randomized Comparison of Bilateral Recession With Unilateral Recession-Resection as Surgery for Infantile Esotropia Completed NCT00304577
14 The Maximal Tolerable Reduction in Hyperopic Correction in Patients With Refractive Accommodative Esotropia: A 6-month Follow-up Study Completed NCT01179711
15 An Observational Study of Infantile, Acquired Non-accommodative, and Acquired Partially-accommodative Esotropia Completed NCT00310960
16 Early Versus Delayed Surgery for Infantile Esotropia: A Clinical Evaluation of Sensory and Motor Outcomes Completed NCT01166503
17 Strabismus Surgery and Driving Ability Completed NCT02570555
18 Augmented Medial Rectus Muscle Recession Versus Medial Rectus Recession With Posterior Scleral Fixation in Partially Accommodative Esotropia Completed NCT02413463
19 Glasses Versus Observation for Moderate Hyperopia in Young Children (HTS1) Completed NCT01515475
20 Bifocal Soft Contact Lenses - Do They Slow Progression of Myopia Relative to Single Vision Soft Contact Lenses in Children and Adolescents? Completed NCT00214487
21 An Observational Study of Optical Correction for Strabismic Amblyopia in Children 3 to <7 Years Old Completed NCT00669539
22 Symmetrical Versus Asymmetrical Inferior Oblique Muscle Weakening Surgery for Asymmetrical Inferior Oblique Overaction Recruiting NCT03507712
23 Botulinum Toxin Augmented Surgery Versus Conventional Surgery in the Management of Large Angle Infantile Esotropia Not yet recruiting NCT03266549
24 The Effect of Light Deprivation on Visual Functions in Adult Amblyopes Not yet recruiting NCT02799836

Search NIH Clinical Center for Monocular Esotropia

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Echothiophate Iodide

Cochrane evidence based reviews: esotropia

Genetic Tests for Monocular Esotropia

Anatomical Context for Monocular Esotropia

MalaCards organs/tissues related to Monocular Esotropia:

41
Eye, Testes, Thyroid, Cortex, Brain, Skin, Bone

Publications for Monocular Esotropia

Articles related to Monocular Esotropia:

(show top 50) (show all 2911)
# Title Authors PMID Year
1
Strabismus in hydrocephalus patients. 38
31115645 2019
2
Optic disc shape in patients with long-lasting unilateral esotropia and exotropia. 38
31420011 2019
3
Clinical characteristics and surgical outcomes of acute acquired Comitant Esotropia. 38
31391009 2019
4
Why bilateral medial rectus recession fails? Factors associated with early repeated surgery. 38
31385144 2019
5
Lateral rectus advancement versus medial rectus recession for consecutive esotropia. 38
31411047 2019
6
Postoperative Correction and Drift After Vertical Rectus Muscle Transposition for Total Sixth Cranial Nerve Palsy. 38
31322714 2019
7
Duane's Retraction Syndrome in a Cohort of South African Children: A 20-Year Clinic-Based Review. 38
31322716 2019
8
Post-operative analysis of pediatric esotropia associated with high hypermetropia. 38
31262252 2019
9
Surgical Responses and Outcomes of Bilateral Medial Rectus Recession in Esotropia With Spinocerebellar Ataxia. 38
31322719 2019
10
The difference of surgical outcomes between manifest exotropia and esotropia. 38
29922977 2019
11
Functional anatomy of extraocular muscles during human vergence compensation of horizontal heterophoria. 38
31042451 2019
12
Cloves Syndrome: A Rare Disorder of Overgrowth with Unusual Features - An Uncommon Phenotype? 38
31334068 2019
13
Pulled into two syndrome (PITS) in a case of congenital fibrosis of the extraocular muscle. 38
31238477 2019
14
Teaching Video NeuroImages: Cerebellar esotropia: A pitfall in ophthalmology and neurology. 38
31262997 2019
15
A novel variant of the human mitochondrial DnaJ protein, Tid1, associates with a human disease exhibiting developmental delay and polyneuropathy. 38
30770860 2019
16
Congenital monocular elevation deficiency associated with a novel TUBB3 gene variant. 38
31302631 2019
17
Outcomes of bilateral lateral rectus recession in treatment of recurrent exotropia after bilateral medial rectus resection. 38
30460864 2019
18
Long-term surgical outcomes of bilateral vs. unilateral medial rectus resection for recurrent exotropia. 38
30814655 2019
19
Recent trend of increasing myopia can be traced to infancy. 38
31203915 2019
20
Pulmonary Hypertension Manifesting as Atrial Arrhythmia in an Anesthetized Child; Diagnosis Using Focused Cardiac Ultrasound (FoCUS). 38
31166056 2019
21
Long-term outcomes of strabismus surgery in Mobius sequence. 38
30958093 2019
22
Identification and Correction of Restrictive Strabismus After Pterygium Excision Surgery. 38
30771334 2019
23
Global and regional prevalence of strabismus: a comprehensive systematic review and meta-analysis. 38
31012389 2019
24
Outcomes following surgery for horizontal strabismus in children of lower socioeconomic backgrounds. 38
31184517 2019
25
Risk factors for strabismus following glaucoma drainage device implantation for refractory childhood glaucoma. 38
31075530 2019
26
Maternal smoking during pregnancy and the risk of strabismus in offspring: a meta-analysis. 38
30402966 2019
27
The flipped-classroom approach to teaching horizontal strabismus in ophthalmology residency: a pilot study. 38
31229609 2019
28
Strabismus Is Correlated with Gross Motor Function in Children with Spastic Cerebral Palsy. 38
31189336 2019
29
Fixation instability during binocular viewing in anisometropic and strabismic children. 38
30006273 2019
30
Factors influencing stereopsis in patients with both refractive accommodative esotropia and amblyopia. 38
29704131 2019
31
Novel variants in the KERA gene cause autosomal recessive cornea plana in a Chinese family: A case report. 38
31059048 2019
32
[Persistent mydriasis after botulinum toxin injection for infantile early onset esotropia]. 38
31208903 2019
33
A Cluster of Cyclic Esotropia: White Matter Changes on MRI and Surgical Outcomes. 38
31116866 2019
34
"Yokoyama procedure" efficacy on non-highly myopic patients with acquired esotropia and hypotropia. 38
31106643 2019
35
[Application of MRI in the etiological diagnosis of special forms of strabismus]. 38
31137148 2019
36
Surgical outcomes after unilateral horizontal rectus surgery in children with infantile esotropia for the correction of A or V pattern. 38
30962069 2019
37
Herpes zoster involving the abducens and vagus nerves without typical skin rash: A case report and literature review. 38
31083257 2019
38
Single Horizontal Muscle (Medial or Lateral Rectus) Transposition and Inferior Rectus Recession in Monocular Elevation Deficit: A Novel Surgical Technique. 38
31116867 2019
39
Faden operation in consecutive esotropia. 38
31073161 2019
40
Photorefractive keratectomy influences the angle of ocular deviation in strabismus patients with hyperopia. 38
29502213 2019
41
The Danish Rural Eye Study: prevalence of strabismus among 3785 Danish adults - a population-based cross-sectional study. 38
31025814 2019
42
Repeat Surgery for Patients Operated in Childhood for Early-Onset Esotropia and Suffering from Persistent Residual, Recurrent or Consecutive Strabismus. 38
30999328 2019
43
Refractive Status in Children with Laser-Treated Retinopathy of Prematurity: Our Experience in Bulgaria. 38
31110577 2019
44
Diagnostic occlusion test for acquired esotropia. 38
30975352 2019
45
Accommodative esotropia and Brown syndrome in a girl with recessive geleophysic dysplasia. 38
30415012 2019
46
Comparison of Surgical Outcomes Between Bilateral Medial Rectus Recession and Unilateral Recess-Resect for Infantile Esotropia. 38
30252566 2019
47
Lateral rectus sag and recurrent esotropia in children. 38
30797977 2019
48
The effects of partial and full correction of refractive errors on sensorial and motor outcomes in children with refractive accommodative esotropia. 38
29549487 2019
49
RERE-Related Disorders 38
30896913 2019
50
Causes and surgical treatment of diplopia and strabismus secondary to myasthenia gravis. 38
30580990 2019

Variations for Monocular Esotropia

Expression for Monocular Esotropia

Search GEO for disease gene expression data for Monocular Esotropia.

Pathways for Monocular Esotropia

GO Terms for Monocular Esotropia

Sources for Monocular Esotropia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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