MCID: MNS012
MIFTS: 20

Monostotic Fibrous Dysplasia

Categories: Bone diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Monostotic Fibrous Dysplasia

MalaCards integrated aliases for Monostotic Fibrous Dysplasia:

Name: Monostotic Fibrous Dysplasia 58
Fibrous Dysplasia, Monostotic 71
Fibrous Dysplasia Monostotic 54
Jaffe-Lichtenstein Disease 58

Classifications:

Orphanet: 58  
Rare bone diseases
Developmental anomalies during embryogenesis


External Ids:

MESH via Orphanet 44 D005358
ICD10 via Orphanet 33 M85.0
UMLS via Orphanet 72 C0016064
Orphanet 58 ORPHA93277
UMLS 71 C0016064

Summaries for Monostotic Fibrous Dysplasia

MalaCards based summary : Monostotic Fibrous Dysplasia, also known as fibrous dysplasia, monostotic, is related to fibrous dysplasia and mazabraud syndrome. An important gene associated with Monostotic Fibrous Dysplasia is GNAS (GNAS Complex Locus). Affiliated tissues include bone, lung and thyroid.

Related Diseases for Monostotic Fibrous Dysplasia

Diseases related to Monostotic Fibrous Dysplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 31)
# Related Disease Score Top Affiliating Genes
1 fibrous dysplasia 11.3
2 mazabraud syndrome 10.7
3 back pain 10.6
4 bone disease 10.5
5 cholesteatoma of middle ear 10.4
6 osteogenic sarcoma 10.4
7 aneurysmal bone cysts 10.4
8 fibroma 10.4
9 ossifying fibroma 10.4
10 syringomyelia, noncommunicating isolated 10.3
11 orbital cyst 10.3
12 syringomyelia 10.3
13 mccune-albright syndrome 10.3
14 dowling-degos disease 1 10.3
15 exophthalmos 10.3
16 pneumothorax, primary spontaneous 10.1
17 branchiootic syndrome 1 10.1
18 autosomal recessive disease 10.1
19 pain agnosia 10.1
20 frontal sinusitis 10.1
21 ehlers-danlos syndrome 10.1
22 pneumothorax 10.1
23 malignant fibrous histiocytoma 10.1
24 thoracic outlet syndrome 10.1
25 fibrosarcoma 10.1
26 radiculopathy 10.1
27 fibrous histiocytoma 10.1
28 precocious puberty 10.1
29 raynaud phenomenon 10.1
30 head injury 10.1
31 paresthesia 10.1

Graphical network of the top 20 diseases related to Monostotic Fibrous Dysplasia:



Diseases related to Monostotic Fibrous Dysplasia

Symptoms & Phenotypes for Monostotic Fibrous Dysplasia

Drugs & Therapeutics for Monostotic Fibrous Dysplasia

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Studies on Tissues From Patients With Fibrous Dysplasia of Bone/McCune-Albright Syndrome and Other Disorders of Calcified Tissues Completed NCT00001973

Search NIH Clinical Center for Monostotic Fibrous Dysplasia

Genetic Tests for Monostotic Fibrous Dysplasia

Anatomical Context for Monostotic Fibrous Dysplasia

MalaCards organs/tissues related to Monostotic Fibrous Dysplasia:

40
Bone, Lung, Thyroid

Publications for Monostotic Fibrous Dysplasia

Articles related to Monostotic Fibrous Dysplasia:

(show top 50) (show all 306)
# Title Authors PMID Year
1
Investigation of the GSalpha gene in the diagnosis of fibrous dysplasia. 61 54
15183415 2004
2
Gsalpha gene mutations in monostotic fibrous dysplasia of bone and fibrous dysplasia-like low-grade central osteosarcoma. 54 61
11561757 2001
3
Etiology of fibrous dysplasia and McCune-Albright syndrome. 54 61
10535539 1999
4
Patients With Isolated Craniofacial Dysplasia Report Better Quality of Life Compared With Those With Craniofacial Dysplasia and Extracranial Involvement. 61
31809491 2020
5
Pathological Fracture of the Tibia in a Monostotic Anterior Cortical Fibrous Dysplasia: Hybrid Fixation with UnicorticalOsteoperiosteal Non-Vascularized Fibula Graft - A Case Report. 61
32548021 2020
6
Monostotic fibrous dysplasia at C7 treated with vertebroplasty: a case report and review of the literature. 61
31706319 2019
7
The surgical management of monostotic fibrous dysplasia of the inferior turbinate. 61
31689546 2019
8
Surgical Treatment of Polyostotic Craniomaxillofacial Fibrous Dysplasia Associated With Acromegalia: The McCune - Albright Syndrome. 61
31033754 2019
9
Monostotic fibrous dysplasia invading the inferior turbinate: computed tomography and magnetic resonance imaging findings. 61
31656356 2019
10
A Rare Case of Radiculopathy: Monostotic Fibrous Dysplasia of the Sacrum. 61
31292029 2019
11
Treatment of diaphyseal pathological fractures in children with monostotic fibrous dysplasia using cortical strut allografts and internal plating: A retrospective clinical study. 61
30702610 2019
12
Locally aggressive monostotic fibrous dysplasia of the cervical spine mimicking malignancy: a case report and literature review. 61
31560341 2019
13
Monostotic Fibrous Dysplasia of the Lumbar Spine With Secondary Features of Solid Variant Aneurysmal Bone Cyst. 61
31321388 2019
14
Midfacial degloving approach for management of the maxillary fibrous dysplasia: a case report. 61
30588475 2018
15
Conservative surgical management of simple monostotic fibrous dysplasia of the proximal femur in a 19-year-old basketballer: a case report. 61
30165901 2018
16
Fibrous dysplasia of bone: Surgical management options and outcomes of 22 cases. 61
29977545 2018
17
Computed Tomography and Magnetic Resonance Imaging Manifestations of Spinal Monostotic Fibrous Dysplasia. 61
30034927 2018
18
Fibrous Dysplasia: Clinicopathologic Presentation of 36 Cases. 61
29744853 2018
19
Congenital double-level cervical spondylolysis: a case report and review of the literature. 61
28247078 2017
20
Determinants of impaired quality of life in patients with fibrous dysplasia. 61
28449700 2017
21
Fibrous Dysplasia in the Epiphysis of the Distal Femur. 61
28231652 2017
22
Fibrous Dysplasia in the Calcaneus. 61
27325625 2017
23
Functional and radiological outcomes of a minimally invasive surgical approach to monostotic fibrous dysplasia. 61
28057011 2017
24
Monostotic fibrous dysplasia of the metacarpal: a case report. 61
28050548 2016
25
Prompt clinical and biochemical response to denosumab in a young adult patient with craniofacial fibrous dysplasia. 61
28228794 2016
26
A Rare Cause of Shoulder Pain: Monostotic Fibrous Dysplasia. 61
29900939 2016
27
Fibrous Dysplasia of the Temporal Bone with External Auditory Canal Stenosis and Secondary Cholesteatoma. 61
27340999 2016
28
Monostotic fibrous dysplasia of the thoracic spine: A case report. 61
26577280 2016
29
Monostotic fibrous dysplasia presenting in maxilla: a case report. 61
28955564 2016
30
Recurrent Monostotic Fibrous Dysplasia in the Mandible. 61
27340572 2016
31
Back pain in Duchenne muscular dystrophy: steroids are not always the culprit. 61
25714938 2016
32
[Monostotic fibrous dysplasia]. 61
27576287 2016
33
A Rare Case of Monostotic Spinal Fibrous Dysplasia Mimicking Solitary Metastatic Lesion of Thyroid Carcinoma. 61
27540330 2016
34
Monosotic fibrous dysplasia and solitary intramuscular myxoma of the head and neck: A unique presentation of Mazabraud's syndrome and a literature review. 61
26722294 2015
35
Multidisciplinary approach for management of a patient with fibrous dysplasia of maxilla. 61
26245286 2015
36
Monostotic fibrous dysplasia with Raynaud's phenomenon. 61
26283854 2015
37
Locally aggressive fibrous dysplasia mimicking malignancy: a report of four cases and review of the literature. 61
25212962 2015
38
Fibrous Dysplasia/McCune-Albright Syndrome 61
25719192 2015
39
Malignant transformation in monostotic fibrous dysplasia: clinical features, imaging features, outcomes in 10 patients, and review. 61
25621678 2015
40
Monostotic fibrous dysplasia of cervical spine. 61
24998792 2015
41
Fibrous dysplasia: an overview of disease process, indications for surgical management, and a case report. 61
25848443 2015
42
Monostotic fibrous dysplasia in the proximal tibial epiphysis: a case report. 61
25526966 2014
43
Clival fibrous dysplasia: Case series and review of the literature. 61
25531855 2014
44
Endoscopic Decompression for Optic Neuropathy in McCune-Albright Syndrome. 61
25368777 2014
45
Monostotic fibrous dysplasia of the mandible. 61
24984642 2014
46
Acromegaly and McCune-Albright syndrome. 61
24517150 2014
47
Monostotic fibrous dysplasia of the proximal femur: natural history and predisposing factors for disease progression. 61
24788504 2014
48
Monostotic Fibrous Dysplasia of the Lumbar Vertebra: A Case Report and Review of the Literature. 61
29252555 2014
49
Monostotic fibrous dysplasia involving occipital bone: a case report and review of literature. 61
25745531 2014
50
Zygomaticomaxillary complex fracture in a zygomatic bone affected by monostotic fibrous dysplasia: a very rare association. 61
23714967 2013

Variations for Monostotic Fibrous Dysplasia

Expression for Monostotic Fibrous Dysplasia

Search GEO for disease gene expression data for Monostotic Fibrous Dysplasia.

Pathways for Monostotic Fibrous Dysplasia

GO Terms for Monostotic Fibrous Dysplasia

Sources for Monostotic Fibrous Dysplasia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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