MCID: MRG001
MIFTS: 25

Morgagni Cataract

Categories: Eye diseases, Genetic diseases

Aliases & Classifications for Morgagni Cataract

MalaCards integrated aliases for Morgagni Cataract:

Name: Morgagni Cataract 12 15
Hypermature Cataract 12
Morgagnian Cataract 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13964
ICD9CM 35 366.18
SNOMED-CT 68 22315007
UMLS 73 C0152258

Summaries for Morgagni Cataract

MalaCards based summary : Morgagni Cataract, also known as hypermature cataract, is related to phacolytic glaucoma and cataract. An important gene associated with Morgagni Cataract is CRYAA (Crystallin Alpha A), and among its related pathways/superpathways are Selenium Micronutrient Network and TP53 Regulates Metabolic Genes. Affiliated tissues include eye and cortex.

Related Diseases for Morgagni Cataract

Diseases related to Morgagni Cataract via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 phacolytic glaucoma 10.3
2 cataract 10.1
3 uveitis 10.1
4 phacoanaphylactic uveitis 10.1
5 phacogenic glaucoma 10.1 CRYAA PHEX
6 iris disease 10.1 CRYAA PHEX
7 senile cataract 10.0 CRYAA GSR
8 lens disease 9.9 CRYAA PHEX

Comorbidity relations with Morgagni Cataract via Phenotypic Disease Network (PDN):


Phacolytic Glaucoma

Graphical network of the top 20 diseases related to Morgagni Cataract:



Diseases related to Morgagni Cataract

Symptoms & Phenotypes for Morgagni Cataract

Drugs & Therapeutics for Morgagni Cataract

Search Clinical Trials , NIH Clinical Center for Morgagni Cataract

Genetic Tests for Morgagni Cataract

Anatomical Context for Morgagni Cataract

MalaCards organs/tissues related to Morgagni Cataract:

41
Eye, Cortex

Publications for Morgagni Cataract

Articles related to Morgagni Cataract:

(show all 17)
# Title Authors Year
1
A case of hypermature cataract formation following implantation of an implantable collamer lens with an Aquaport. ( 28730098 )
2017
2
Impact of lens thickness on complications of hypermature cataract surgery: A prospective study. ( 27553178 )
2016
3
Intraocular pressure, specular microscopy, and prostaglandin E2 concentration in dogs with mature and hypermature cataract. ( 24450881 )
2014
4
Spontaneous rupture of lens capsule with dislocation of nucleus in hypermature cataract. ( 25341832 )
2014
5
Continuous curvilinear capsulorhexis in intumescent or hypermature cataract with liquefied cortex. ( 12663001 )
2003
6
Phacoemulsification of white hypermature cataract. ( 10445205 )
1999
7
Fluorescein blue, light-assisted capsulorhexis for mature or hypermature cataract. ( 9494894 )
1998
8
Study of the substructure of the Morgagni and Brunescens cataract with the TAO non-coating technique. Part 1: Morgagni cataract. ( 1305020 )
1992
9
Hypermature cataract in a crested mynah, Leucopsar rothschildi. ( 6887443 )
1983
10
Dehydration of the crystalline lens: a possible means of extracting the hypermature cataract. ( 5068226 )
1972
11
GLAUCOMA DUE TO HYPERMATURE CATARACT: THE USE OF UREA IN DIAGNOSIS. ( 14045352 )
1963
12
A modified erisophake. Extraction of a hypermature (Morgagni) cataract. ( 13903577 )
1962
13
The hypermature cataract. ( 13691280 )
1960
14
Completely Dislocated Hypermature Cataract and Glaucoma. ( 16693572 )
1959
15
Complications and treatment of the hypermature cataract. ( 13635719 )
1958
16
Complications & treatment of hypermature cataract. ( 13635721 )
1958
17
Lens-induced uveitis and glaucoma. III. "Phacogenetic glaucoma": lens-induced glaucoma; mature or hypermature cataract; open iridocorneal angle. ( 14914837 )
1952

Variations for Morgagni Cataract

Expression for Morgagni Cataract

Search GEO for disease gene expression data for Morgagni Cataract.

Pathways for Morgagni Cataract

GO Terms for Morgagni Cataract

Cellular components related to Morgagni Cataract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.23 CALD1 CRYAA GAPDH GSR HHEX PRDX5

Biological processes related to Morgagni Cataract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to oxidative stress GO:0034599 9.26 GSR PRDX5
2 oxidation-reduction process GO:0055114 9.26 GAPDH GSR PRDX5 TXN
3 cellular oxidant detoxification GO:0098869 9.16 GSR PRDX5
4 cell redox homeostasis GO:0045454 8.8 GSR PRDX5 TXN

Molecular functions related to Morgagni Cataract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADP binding GO:0050661 8.62 GAPDH GSR

Sources for Morgagni Cataract

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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