MCID: MRG001
MIFTS: 20

Morgagni Cataract

Categories: Eye diseases, Genetic diseases

Aliases & Classifications for Morgagni Cataract

MalaCards integrated aliases for Morgagni Cataract:

Name: Morgagni Cataract 12 15
Hypermature Cataract 12
Morgagnian Cataract 71

Classifications:



External Ids:

Disease Ontology 12 DOID:13964
ICD9CM 34 366.18
SNOMED-CT 67 22315007
UMLS 71 C0152258

Summaries for Morgagni Cataract

Disease Ontology : 12 A senile cataract that is characterized by dense white opacification of the lens and milky fluid in the lens capsule such that the dense nucleus of the lens sinks in the surrounding fluid. It is the late stage of senile cataracts and is caused by a multifactorial etiology related to aging.

MalaCards based summary : Morgagni Cataract, also known as hypermature cataract, is related to mature cataract and intraocular pressure quantitative trait locus. An important gene associated with Morgagni Cataract is CRYAA (Crystallin Alpha A). Affiliated tissues include eye.

Related Diseases for Morgagni Cataract

Diseases related to Morgagni Cataract via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 mature cataract 30.6 CRYAA CPAMD8
2 intraocular pressure quantitative trait locus 10.6
3 corneal edema 10.5
4 phacolytic glaucoma 10.5
5 uveitis 10.4
6 cataract 10.2
7 immature cataract 10.2 MPDU1 CRYAA
8 orbital cellulitis 10.2 MPDU1 CRYAA
9 steroid-induced glaucoma 10.2 PEX19 CRYAA
10 acute orbital inflammation 10.2 MPDU1 CRYAA
11 phimosis 10.2 PEX19 CRYAA
12 phacogenic glaucoma 10.2 PEX19 CRYAA
13 melanoma, uveal 10.2
14 astigmatism 10.2
15 pars planitis 10.2
16 hypopyon 10.2
17 senile cataract 10.2
18 vitreous disease 10.2
19 phacoanaphylactic uveitis 10.2
20 juvenile glaucoma 10.1 PEX19 CRYAA
21 acute closed-angle glaucoma 10.1 PEX19 CBARP
22 iris disease 10.0 PEX19 CRYAA
23 lens subluxation 10.0 PEX19 MPDU1 CRYAA
24 uveal disease 10.0 PEX19 CRYAA
25 glaucoma, primary open angle 9.9 PEX19 GMDS CRYAA
26 posterior polar cataract 9.9 CRYGA CRYAA
27 lens disease 9.8 PEX19 CRYAA
28 scleral staphyloma 9.7 CRYGA CRYAA CBARP

Comorbidity relations with Morgagni Cataract via Phenotypic Disease Network (PDN):


Phacolytic Glaucoma

Graphical network of the top 20 diseases related to Morgagni Cataract:



Diseases related to Morgagni Cataract

Symptoms & Phenotypes for Morgagni Cataract

Drugs & Therapeutics for Morgagni Cataract

Search Clinical Trials , NIH Clinical Center for Morgagni Cataract

Genetic Tests for Morgagni Cataract

Anatomical Context for Morgagni Cataract

MalaCards organs/tissues related to Morgagni Cataract:

40
Eye

Publications for Morgagni Cataract

Articles related to Morgagni Cataract:

(show all 31)
# Title Authors PMID Year
1
Morgagnian Cataract. 61
31392333 2019
2
Acute Phacolytic Glaucoma and Morgagnian Cataract. 61
30973585 2019
3
Femtosecond laser-assisted cataract surgery for the white cataract. 61
29907631 2019
4
Multimodal imaging in an idiopathic spontaneously absorbed cataractous lens: A rare case report. 61
30841756 2019
5
Study of congenital Morgagnian cataracts in Holstein calves. 61
31877171 2019
6
"Triangle sign" in Morgagnian cataract. 61
30574920 2019
7
Zepto-rhexis: A new surgical technique of capsulorhexis using precision nano-pulse technology in difficult cataract cases. 61
30038166 2018
8
[Morgagnian cataract]. 61
29515742 2017
9
Intraocular lens scaffold technique to prevent posterior capsule rupture in cases of Morgagnian cataract. 61
28317682 2017
10
Morgagnian cataract resulting from a naturally occurring nonsense mutation elucidates a role of CPAMD8 in mammalian lens development. 61
28683140 2017
11
[Post-traumatic Morgagnian cataract]. 61
26987897 2016
12
Images in clinical medicine. Morgagnian cataract. 61
24918375 2014
13
[Sunset (Morgagnian) cataract]. 61
22464866 2012
14
Non-Invasive Couching Technique to Treat a Morgagnian Cataract Causing Bullous Keratopathy. 61
20438042 2010
15
Visco-shell technique with sodium hyaluronate 2.3% in phacoemulsification of Morgagnian cataract. 61
19006724 2008
16
Morgagnian cataract with an isolated posterior capsular opening. 61
14557192 2003
17
Phacofragmentation for morgagnian cataract in a horse. 61
11722788 2001
18
Na,K-ATPase in lens epithelia from patients with senile cataracts. 61
10560239 1999
19
The Morgagnian and Brunescens cataract morphology studied with with SEM and TEM. 61
8398567 1993
20
Study of the substructure of the Morgagni and Brunescens cataract with the TAO non-coating technique. Part 1: Morgagni cataract. 61
1305020 1992
21
Study of the substructure of the Morgagni and Brunescens cataract with the TAO non-coating technique. Part 2: Brunescens cataract. 61
1305021 1992
22
Acidic lens-protein-degrading activity in aqueous humour. 61
3758213 1986
23
[Double refraction of crystals in the lens (spheroliths, "Christmas tree ornaments") and in the vitreous body (scintillatio nivea)]. 61
7160640 1982
24
["Spontaneous healing" of hypermature Morgagnian cataract: case report with photographs (author's transl)]. 61
7421056 1980
25
Unilateral Morgagnian cataract. 61
893943 1977
26
Morgagnian cataract. 61
1070881 1976
27
A modified erisophake. Extraction of a hypermature (Morgagni) cataract. 61
13903577 1962
28
[Overripe Morgagni cataract and its complications]. 61
14038798 1962
29
The morgagnian cataract: its characteristics and surgery. 61
14388100 1955
30
[Phacogenetic ophthalmia in morgagnian cataract; clinical and histological observations on two cases of hypermature cataract with spontaneous capsular defects with contralateral aphakia]. 61
13131740 1953
31
Observations on Glaucoma in Morgagnian Cataract. 61
16692750 1926

Variations for Morgagni Cataract

Expression for Morgagni Cataract

Search GEO for disease gene expression data for Morgagni Cataract.

Pathways for Morgagni Cataract

GO Terms for Morgagni Cataract

Molecular functions related to Morgagni Cataract according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of eye lens GO:0005212 8.62 CRYGA CRYAA

Sources for Morgagni Cataract

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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