MCID: MRP002
MIFTS: 31

Morpheaform Basal Cell Carcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Morpheaform Basal Cell Carcinoma

MalaCards integrated aliases for Morpheaform Basal Cell Carcinoma:

Name: Morpheaform Basal Cell Carcinoma 12 15
Morphea-Type Basal Cell Carcinoma 12
Cicatricial Basal-Cell Carcinoma 12
Basal Cell Carcinoma, Morphea 12
Morpheic Basal Cell Carcinoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4292
NCIt 50 C27182
SNOMED-CT 68 56665009
UMLS 73 C0555191

Summaries for Morpheaform Basal Cell Carcinoma

MalaCards based summary : Morpheaform Basal Cell Carcinoma, also known as morphea-type basal cell carcinoma, is related to basal cell carcinoma and malignant syringoma. An important gene associated with Morpheaform Basal Cell Carcinoma is DAND5 (DAN Domain BMP Antagonist Family Member 5), and among its related pathways/superpathways are Developmental Biology and Circadian entrainment. Affiliated tissues include skin, lung and kidney, and related phenotype is digestive/alimentary.

Related Diseases for Morpheaform Basal Cell Carcinoma

Diseases related to Morpheaform Basal Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 71)
# Related Disease Score Top Affiliating Genes
1 basal cell carcinoma 30.5 KRT15 KRT17 KRT19 KRT20 PHLDA1
2 malignant syringoma 30.2 DAND5 KRT15 KRT20
3 basal cell carcinoma 1 10.6
4 fibroepithelial basal cell carcinoma 10.2 KRT20 PHLDA1
5 nodular basal cell carcinoma 10.2 KRT15 KRT17
6 eccrine acrospiroma 10.2 KRT15 KRT17
7 sweat gland disease 10.2 DAND5 KRT15
8 angiosarcoma 10.1
9 ampulla of vater adenocarcinoma 10.1 KRT17 KRT20
10 ovarian mucinous neoplasm 10.1 KRT17 KRT20
11 ovarian large-cell neuroendocrine carcinoma 10.1 KRT20 NCAM1
12 cutaneous ganglioneuroma 10.1 KRT20 NCAM1
13 superior mesenteric artery syndrome 10.1 KRT17 KRT19
14 ampulla of vater cancer 10.1 KRT17 KRT20
15 pregnancy adenoma 10.1 KRT17 KRT19
16 renal pelvis carcinoma 10.1 KRT19 KRT20
17 apocrine adenocarcinoma 10.1 AR KRT15
18 biliary papillomatosis 10.1 KRT19 KRT20
19 rete testis neoplasm 10.1 KRT20 NCAM1
20 cystadenofibroma 10.1 KRT20 NCAM1
21 actinic keratosis 10.1 KRT17 KRT20
22 thymus lipoma 10.1 KRT19 KRT20
23 sweat gland cancer 10.1 KRT15 KRT20
24 immune system organ benign neoplasm 10.1 KRT19 KRT20
25 brachydactyly, type e1 10.1 KRT19 KRT20
26 cervical clear cell adenocarcinoma 10.1 KRT19 NCAM1
27 large cell neuroendocrine carcinoma 10.1 KRT20 NCAM1
28 primary cutaneous amyloidosis 10.1 KRT17 KRT19
29 meibomian cyst 10.1 AR KRT20
30 paget disease, extramammary 10.0 AR KRT20
31 anterior scleritis 10.0 KRT19 NCAM1
32 basal cell carcinoma, infundibulocystic 10.0 KRT17 KRT20 PHLDA1
33 small cell carcinoma 10.0 KRT20 NCAM1
34 corneal abscess 10.0 AR KRT19
35 cystitis cystica 10.0 AR KRT20
36 eccrine sweat gland neoplasm 10.0 KRT15 KRT17 KRT20
37 merkel cell carcinoma 10.0 KRT20 NCAM1
38 localized scleroderma 10.0
39 large intestine adenocarcinoma 10.0 CDH1 KRT20
40 linitis plastica 10.0 CDH1 KRT20
41 adenoid squamous cell carcinoma 10.0 CDH1 KRT20
42 goblet cell carcinoid 10.0 CDH1 KRT20
43 gastric diffuse adenocarcinoma 10.0 CDH1 KRT20
44 lymphoepithelioma-like carcinoma 10.0 CDH1 KRT20
45 extrahepatic bile duct adenocarcinoma 10.0 CDH1 NCAM1
46 bile duct adenocarcinoma 10.0 CDH1 KRT19
47 renal pelvis adenocarcinoma 10.0 CDH1 KRT19
48 pre-malignant neoplasm 10.0 CDH1 KRT17
49 polycystic liver disease 1 with or without kidney cysts 10.0 KRT17 KRT19 KRT20
50 signet ring cell adenocarcinoma 9.9 CDH1 KRT20

Graphical network of the top 20 diseases related to Morpheaform Basal Cell Carcinoma:



Diseases related to Morpheaform Basal Cell Carcinoma

Symptoms & Phenotypes for Morpheaform Basal Cell Carcinoma

MGI Mouse Phenotypes related to Morpheaform Basal Cell Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.02 AR CDH1 KRT15 KRT17 KRT19

Drugs & Therapeutics for Morpheaform Basal Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Morpheaform Basal Cell Carcinoma

Genetic Tests for Morpheaform Basal Cell Carcinoma

Anatomical Context for Morpheaform Basal Cell Carcinoma

MalaCards organs/tissues related to Morpheaform Basal Cell Carcinoma:

41
Skin, Lung, Kidney, Liver, Testis, Thymus

Publications for Morpheaform Basal Cell Carcinoma

Articles related to Morpheaform Basal Cell Carcinoma:

(show all 12)
# Title Authors Year
1
Radiotherapy of morphea-type basal cell carcinoma: results in 127 cases. ( 25564683 )
2014
2
Fluorouracil and Other Predictors of Morpheaform Basal Cell Carcinoma Among High-Risk Patients: The Veterans Affairs Topical Tretinoin Chemoprevention Trial. ( 24258386 )
2013
3
The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers. ( 23398472 )
2013
4
Diagnostic utility of cytokeratin 17 immunostaining in morpheaform basal cell carcinoma and for facilitating the detection of tumor cells at the surgical margins. ( 22691048 )
2012
5
Commentary: diagnostic utility of cytokeratin 17 immunostaining in morpheaform basal cell carcinoma and for facilitating the detection of tumor cells at the surgical margins. ( 22861061 )
2012
6
Photodynamic therapy as adjunctive therapy for morpheaform basal cell carcinoma. ( 21879201 )
2011
7
Angiosarcoma clinically resembling morpheaform basal cell carcinoma. ( 18637812 )
2008
8
Morpheaform basal cell carcinoma in African Americans. ( 15606838 )
2004
9
Can smoking and/or occupational UV exposure have any role in the development of the morpheaform basal cell carcinoma? A critical role for peritumoral mast cells. ( 12100702 )
2002
10
Analysis of morpheaform basal cell carcinoma. ( 3220994 )
1988
11
Morpheaform basal cell carcinoma in a young black woman. ( 3343426 )
1988
12
Morpheaform basal cell carcinoma. ( 5676900 )
1968

Variations for Morpheaform Basal Cell Carcinoma

Expression for Morpheaform Basal Cell Carcinoma

Search GEO for disease gene expression data for Morpheaform Basal Cell Carcinoma.

Pathways for Morpheaform Basal Cell Carcinoma

Pathways related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.84 DAND5 KRT15 KRT17 KRT19 KRT20 NCAM1
2
Show member pathways
12.43 KRT15 KRT17 KRT19 KRT20
3 11.75 CDH1 KRT17 KRT19 KRT20
4
Show member pathways
11.38 KRT15 KRT17 KRT19 KRT20
5 10.99 CDH1 NCAM1

GO Terms for Morpheaform Basal Cell Carcinoma

Cellular components related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.7 AR KRT15 KRT17 KRT19 KRT20 NCAM1
2 cell periphery GO:0071944 8.96 KRT17 KRT19
3 intermediate filament GO:0005882 8.92 KRT15 KRT17 KRT19 KRT20

Biological processes related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.26 KRT15 KRT17 KRT19 KRT20
2 intermediate filament organization GO:0045109 9.16 KRT17 KRT20
3 cornification GO:0070268 8.92 KRT15 KRT17 KRT19 KRT20

Molecular functions related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.92 KRT15 KRT17 KRT19 KRT20

Sources for Morpheaform Basal Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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