MCID: MRP002
MIFTS: 22

Morpheaform Basal Cell Carcinoma

Categories: Cancer diseases, Skin diseases
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Aliases & Classifications for Morpheaform Basal Cell Carcinoma

MalaCards integrated aliases for Morpheaform Basal Cell Carcinoma:

Name: Morpheaform Basal Cell Carcinoma 11 14
Morphea-Type Basal Cell Carcinoma 11
Cicatricial Basal-Cell Carcinoma 11
Basal Cell Carcinoma, Morphea 11
Morpheic Basal Cell Carcinoma 71

Classifications:



External Ids:

Disease Ontology 11 DOID:4292
NCIt 49 C27182
SNOMED-CT 68 403913006
UMLS 71 C0555191

Summaries for Morpheaform Basal Cell Carcinoma

MalaCards based summary: Morpheaform Basal Cell Carcinoma, also known as morphea-type basal cell carcinoma, is related to basal cell carcinoma and localized scleroderma. An important gene associated with Morpheaform Basal Cell Carcinoma is KRT15 (Keratin 15), and among its related pathways/superpathways are Keratinization and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include skin.

Related Diseases for Morpheaform Basal Cell Carcinoma

Diseases related to Morpheaform Basal Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 basal cell carcinoma 30.1 KRT20 KRT17 KRT15 CD34
2 localized scleroderma 29.8 COL1A1 CD34
3 malignant syringoma 29.3 PHLDA1 KRT20 KRT17 KRT15 CD34
4 basal cell carcinoma 1 10.8
5 angiosarcoma 10.3
6 skin carcinoma 10.2
7 pilar sheath acanthoma 10.1 PHLDA1 KRT15
8 epidermal appendage tumor 10.1 PHLDA1 KRT15
9 basosquamous carcinoma 10.1 PHLDA1 KRT15
10 syringocystadenoma papilliferum 10.1 PHLDA1 KRT15
11 hidrocystoma 10.1 PHLDA1 KRT15
12 eccrine sweat gland cancer 10.1 PHLDA1 KRT15
13 hidradenoma 10.0 PHLDA1 KRT15
14 cystic basal cell carcinoma 10.0 KRT20 KRT15
15 epidermolysis bullosa 10.0 KRT17 KRT15
16 infiltrative basal cell carcinoma 10.0 KRT17 KRT15
17 inverted follicular keratosis 10.0 PHLDA1 KRT17
18 eccrine papillary adenoma 9.9 KRT20 KRT17
19 borst-jadassohn intraepidermal carcinoma 9.9 KRT20 KRT17
20 polycystic liver disease 1 with or without kidney cysts 9.9 KRT20 KRT17
21 fibroepithelial basal cell carcinoma 9.8 PHLDA1 KRT20 KRT15
22 squamous papillomatosis 9.8 PHLDA1 KRT20 KRT15
23 colonic lymphangioma 9.8 KRT20 CD34
24 sweat gland cancer 9.8 PHLDA1 KRT20 KRT15
25 lymphangioma 9.8 KRT20 CD34
26 skin sarcoma 9.8 COL1A1 CD34
27 pulmonary artery leiomyosarcoma 9.8 KRT20 CD34
28 ampulla of vater cancer 9.8 KRT20 KRT17
29 central epithelioid sarcoma 9.8 KRT20 CD34
30 sweat gland disease 9.8 KRT15 CD34
31 vulvar proximal-type epithelioid sarcoma 9.8 KRT20 CD34
32 cutaneous ganglioneuroma 9.8 KRT20 CD34
33 keratoacanthoma 9.8 KRT17 KRT15
34 cystic teratoma 9.8 KRT20 CD34
35 breast fibroadenoma 9.8 KRT15 CD34
36 hair follicle neoplasm 9.8 PHLDA1 KRT17 KRT15
37 cutaneous fibrous histiocytoma 9.8 COL1A1 CD34
38 pilomatrixoma 9.8 PHLDA1 KRT17 KRT15
39 pseudosarcomatous fibromatosis 9.8 COL1A1 CD34
40 epidermolytic hyperkeratosis 9.7 KRT17 KRT15
41 benign teratoma 9.7 KRT20 CD34
42 epidermolysis bullosa simplex 9.7 KRT17 KRT15 COL1A1
43 clear cell basal cell carcinoma 9.7 PHLDA1 KRT20 KRT17
44 intestinal obstruction 9.7 KRT20 CD34
45 dermatofibrosarcoma protuberans 9.7 COL1A1 CD34
46 epithelioid sarcoma 9.6 KRT20 KRT15 CD34
47 skin benign neoplasm 9.6 KRT20 COL1A1 CD34
48 follicular infundibulum tumor 9.5 PHLDA1 KRT20 KRT17 KRT15
49 systemic scleroderma 9.5 COL1A1 CD34

Graphical network of the top 20 diseases related to Morpheaform Basal Cell Carcinoma:



Diseases related to Morpheaform Basal Cell Carcinoma

Symptoms & Phenotypes for Morpheaform Basal Cell Carcinoma

Drugs & Therapeutics for Morpheaform Basal Cell Carcinoma

Search Clinical Trials, NIH Clinical Center for Morpheaform Basal Cell Carcinoma

Genetic Tests for Morpheaform Basal Cell Carcinoma

Anatomical Context for Morpheaform Basal Cell Carcinoma

Organs/tissues related to Morpheaform Basal Cell Carcinoma:

MalaCards : Skin

Publications for Morpheaform Basal Cell Carcinoma

Articles related to Morpheaform Basal Cell Carcinoma:

(show all 36)
# Title Authors PMID Year
1
Does Immunohistochemistry Add to Morphology in Differentiating Trichoepithelioma, Desmoplastic Trichoepithelioma, Morpheaform Basal Cell Carcinoma, and Microcystic Adnexal Carcinoma? 62
35384877 2022
2
A pearly nodule on an indurated plaque. 62
35499445 2021
3
Morpheaform Basal Cell Carcinoma Masquerading as Desmoplastic Trichoepithelioma in a Young Patient. 62
35283517 2021
4
Orbito-scleral-sinus invasion of basal cell carcinoma in an immunocompromised patient on vismodegib. 62
32283962 2021
5
Dermoscopic characteristics of microcystic adnexal carcinoma, desmoplastic trichoepithelioma, and morpheaform basal cell carcinoma. 62
32686120 2021
6
A Non-Surgical and Cost-Effective Treatment Approach Employing Topical Imiquimod, 5-Fluorouracil, and Tretinoin for Primary Non-Melanoma Skin Cancers. 62
33683072 2021
7
Angiosarcoma imitating a morpheaform basal cell carcinoma. 62
32186542 2020
8
Microcystic Adnexal Carcinoma and a Summary of Other Rare Malignant Adnexal Tumours. 62
28681209 2017
9
Morpheaform Basal Cell Carcinomas With Areas of Predominantly Single-Cell Pattern of Infiltration: Diagnostic Utility of p63 and Cytokeratin. 62
27043336 2016
10
Comparative analysis of cytokeratin 15, TDAG51, cytokeratin 20 and androgen receptor in sclerosing adnexal neoplasms and variants of basal cell carcinoma. 62
26016446 2015
11
Desmoplastic trichoepithelioma: A clinicopathological study of three cases and a review of the literature. 62
26622873 2015
12
Histological and immunohistochemical study of the eyelid basal cell carcinomas. 62
26429176 2015
13
Radiotherapy of morphea-type basal cell carcinoma: results in 127 cases. 62
25564683 2014
14
Fluorouracil and other predictors of morpheaform basal cell carcinoma among high-risk patients: the Veterans Affairs Topical Tretinoin Chemoprevention Trial. 62
24258386 2014
15
The immunohistochemical differential diagnosis of microcystic adnexal carcinoma, desmoplastic trichoepithelioma and morpheaform basal cell carcinoma using BerEP4 and stem cell markers. 62
23398472 2013
16
Diagnostic utility of cytokeratin 17 immunostaining in morpheaform basal cell carcinoma and for facilitating the detection of tumor cells at the surgical margins. 62
22691048 2012
17
Commentary: diagnostic utility of cytokeratin 17 immunostaining in morpheaform basal cell carcinoma and for facilitating the detection of tumor cells at the surgical margins. 62
22861061 2012
18
Photodynamic therapy as adjunctive therapy for morpheaform basal cell carcinoma. 62
21879201 2011
19
Desmoplastic trichoepithelioma, infiltrative/morpheaform BCC, and microcystic adnexal carcinoma: differentiation by immunohistochemistry and determining the need for Mohs micrographic surgery. 62
20540416 2010
20
Angiosarcoma clinically resembling morpheaform basal cell carcinoma. 62
18637812 2008
21
Three different consecutive manifestations of morphoeic BCC in the same patient: presenting first as ectropion, then entropion, and finally medial canthal dystopia with epicanthus inversus. 62
18569825 2008
22
The expression of CD23 in cutaneous non-lymphoid neoplasms. 62
17696916 2007
23
Morpheaform basal cell carcinoma in African Americans. 62
15606838 2004
24
[Sclerodermiform basal cell carcinoma (morphea-like basal cell carcinoma)]. 62
15107757 2004
25
Predictors of extensive subclinical spread in nonmelanoma skin cancer treated with Mohs micrographic surgery. 62
12164742 2002
26
Can smoking and/or occupational UV exposure have any role in the development of the morpheaform basal cell carcinoma? A critical role for peritumoral mast cells. 62
12100702 2002
27
Serial excision of a large facial skin cancer. 62
10759829 2000
28
Clinical factors influencing periocular surgical defects after Mohs micrographic surgery. 62
10189634 1999
29
Nodular desmoplastic variant of trichoblastoma. 62
7513504 1994
30
Analysis of morpheaform basal cell carcinoma. 62
3220994 1988
31
Morpheaform basal cell carcinoma in a young black woman. 62
3343426 1988
32
Dermatofibrosarcoma non-protuberans: description and report of five cases of a morpheaform variant of dermatofibrosarcoma. 62
2578589 1985
33
Auricular malignant neoplasms. Identification of high-risk lesions and selection of method of reconstruction. 62
7073593 1982
34
Auricular malignant neoplasms. When is chemotherapy (Mohs' technique) necessary? 62
7295168 1981
35
Desmoplastic malignant melanoma. 62
1137419 1975
36
Morpheaform basal cell carcinoma. 62
5676900 1968

Variations for Morpheaform Basal Cell Carcinoma

Expression for Morpheaform Basal Cell Carcinoma

Search GEO for disease gene expression data for Morpheaform Basal Cell Carcinoma.

Pathways for Morpheaform Basal Cell Carcinoma

Pathways related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.34 KRT20 KRT17 KRT15
2 11.08 COL1A1 CD34

GO Terms for Morpheaform Basal Cell Carcinoma

Cellular components related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 9.02 KRT20 KRT17 KRT15
2 cell periphery GO:0071944 8.96 KRT17 CD34

Biological processes related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 epithelial cell differentiation GO:0030855 9.43 KRT20 KRT17 KRT15
2 intermediate filament organization GO:0045109 9.1 KRT20 KRT17 KRT15

Molecular functions related to Morpheaform Basal Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 8.92 KRT20 KRT17 KRT15

Sources for Morpheaform Basal Cell Carcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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