MCID: MTR086
MIFTS: 16

Motor Stereotypies

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Motor Stereotypies

MalaCards integrated aliases for Motor Stereotypies:

Name: Motor Stereotypies 58

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Orphanet 58 ORPHA306765

Summaries for Motor Stereotypies

MalaCards based summary : Motor Stereotypies is related to autism and tic disorder. An important gene associated with Motor Stereotypies is IL6R (Interleukin 6 Receptor). Affiliated tissues include brain, eye and testes.

Related Diseases for Motor Stereotypies

Diseases related to Motor Stereotypies via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 autism 10.5
2 tic disorder 10.5
3 attention deficit-hyperactivity disorder 10.4
4 autism spectrum disorder 10.4
5 movement disease 10.3
6 obsessive-compulsive disorder 10.3
7 alacrima, achalasia, and mental retardation syndrome 10.3
8 gilles de la tourette syndrome 10.2
9 pervasive developmental disorder 10.1
10 frontotemporal dementia 10.0
11 striatal degeneration, autosomal dominant 2 10.0
12 speech and communication disorders 10.0
13 visual epilepsy 10.0
14 dementia 10.0
15 learning disability 10.0
16 seizure disorder 10.0
17 audiogenic seizures 10.0
18 serotonin syndrome 10.0

Graphical network of the top 20 diseases related to Motor Stereotypies:



Diseases related to Motor Stereotypies

Symptoms & Phenotypes for Motor Stereotypies

Drugs & Therapeutics for Motor Stereotypies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Cerebral Activity Related to Primary Motor Stereotypies in Children: An EEG Study Completed NCT01037361
2 Behavioral Therapy for Tourette Syndrome: Home-Based and Therapist-Administered Completed NCT03019731

Search NIH Clinical Center for Motor Stereotypies

Genetic Tests for Motor Stereotypies

Anatomical Context for Motor Stereotypies

MalaCards organs/tissues related to Motor Stereotypies:

40
Brain, Eye, Testes, Subthalamic Nucleus

Publications for Motor Stereotypies

Articles related to Motor Stereotypies:

(show top 50) (show all 125)
# Title Authors PMID Year
1
Cortical endogenous opioids and their role in facilitating repetitive behaviors in deer mice. 61
31676208 2020
2
Lesion of striatal patches disrupts habitual behaviors and increases behavioral variability. 61
31914121 2020
3
Children with primary complex motor stereotypies show impaired reactive but not proactive inhibition. 61
31935639 2019
4
Prevalence and determinants of motor stereotypies in autism spectrum disorder: A systematic review and meta-analysis. 61
31552746 2019
5
Deletion of Autism Risk Gene Shank3 Disrupts Prefrontal Connectivity. 61
31061091 2019
6
EEG Abnormalities as a Neurophysiological Biomarker of Severity in Autism Spectrum Disorder: A Pilot Cohort Study. 61
30726535 2019
7
Hypothesis-driven investigations of diverse pharmacological targets in two mouse models of autism. 61
30653853 2019
8
Home-based Sensory Interventions in Children with Autism Spectrum Disorder: A Randomized Controlled Trial. 61
30043192 2019
9
SYT1-associated neurodevelopmental disorder: a case series. 61
30107533 2018
10
Home-Based, Therapist-Assisted, Therapy for Young Children With Primary Complex Motor Stereotypies. 61
30049425 2018
11
Comorbid epilepsy in autism spectrum disorder: Implications of postnatal inflammation for brain excitability. 61
29858515 2018
12
Striatonigral direct pathway activation is sufficient to induce repetitive behaviors. 61
28939413 2018
13
Being vs. Appearing Socially Uninterested: Challenging Assumptions about Social Motivation in Autism. 61
29914590 2018
14
Stereotypic Movement Disorders. 61
29735112 2018
15
A cross-species comparison of abnormal behavior in three species of singly-housed old world monkeys. 61
29422700 2018
16
Behavioral Phenotyping of Dopamine Transporter Knockout Rats: Compulsive Traits, Motor Stereotypies, and Anhedonia. 61
29520239 2018
17
Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome. 61
29016856 2017
18
Differential behavioral and molecular alterations upon protracted abstinence from cocaine versus morphine, nicotine, THC and alcohol. 61
27126842 2017
19
Molecular and clinical delineation of 2p15p16.1 microdeletion syndrome. 61
28573701 2017
20
Efficacy of parent-delivered behavioral therapy for primary complex motor stereotypies. 61
27259464 2017
21
Childhood motor stereotypies: questions of definition and management. 61
27292128 2017
22
Motor Stereotypies: A Pathophysiological Review. 61
28405185 2017
23
Anomalous Putamen Volume in Children With Complex Motor Stereotypies. 61
27751663 2016
24
Novel Object Exploration as a Potential Assay for Higher Order Repetitive Behaviors in Mice. 61
27583676 2016
25
GABA and Glutamate in Children with Primary Complex Motor Stereotypies: An 1H-MRS Study at 7T. 61
26542237 2016
26
Developmental Profile and Diagnoses in Children Presenting with Motor Stereotypies. 61
27933285 2016
27
Intense Imagery Movements (IIM): More to motor stereotypies than meets the eye. 61
26561043 2016
28
A field guide to current advances in paediatric movement disorders. 61
26110804 2015
29
Novel object exploration in the C58/J mouse model of autistic-like behavior. 61
25532914 2015
30
Primary complex motor stereotypies in older children and adolescents: clinical features and longitudinal follow-up. 61
25661287 2015
31
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: an overview. 61
24953744 2014
32
Intense imagery movements: a common and distinct paediatric subgroup of motor stereotypies. 61
24947872 2014
33
Neuropsychological function in children with primary complex motor stereotypies. 61
24814517 2014
34
Do children with primary complex motor stereotypies only have movement problems? 61
24920003 2014
35
Absent movement-related cortical potentials in children with primary motor stereotypies. 61
24259275 2014
36
Simple motor stereotypies are not specific features of behavioural frontotemporal dementia. 61
24534731 2014
37
Prefrontal seizures manifesting as motor stereotypies. 61
24142450 2014
38
Anti-brain antibodies are associated with more severe cognitive and behavioral profiles in Italian children with Autism Spectrum Disorder. 61
24389156 2014
39
Long-term behavioral effects of neonatal blockade of gastrin-releasing peptide receptors in rats: similarities to autism spectrum disorders. 61
24462726 2014
40
Abnormal behavior and associated risk factors in captive baboons (Papio hamadryas spp.). 61
24323406 2014
41
Ethological approach to autism spectrum disorders. 61
25299761 2014
42
A retrospective study of toddlers with autism spectrum disorder: Clinical and developmental profile. 61
24753655 2014
43
A guide to childhood motor stereotypies, tic disorders and the tourette spectrum for the primary care practitioner. 61
24757265 2014
44
Oxotremorine treatment reduces repetitive behaviors in BTBR T+ tf/J mice. 61
25165445 2014
45
Motor control, habits, complex motor stereotypies, and Tourette syndrome. 61
24175737 2013
46
Motor stereotypies and cognitive perseveration in non-human primates exposed to early gestational irradiation. 61
23769911 2013
47
Motor stereotypies and volumetric brain alterations in children with Autistic Disorder. 61
23637709 2013
48
The Effects of Predictability in Daily Husbandry Routines on Captive Rhesus Macaques (Macaca mulatta). 61
23439920 2013
49
Raclopride or high-frequency stimulation of the subthalamic nucleus stops cocaine-induced motor stereotypy and restores related alterations in prefrontal basal ganglia circuits. 61
22845853 2012
50
Development, cognition, and behaviour in Pitt-Hopkins syndrome. 61
22712893 2012

Variations for Motor Stereotypies

Expression for Motor Stereotypies

Search GEO for disease gene expression data for Motor Stereotypies.

Pathways for Motor Stereotypies

GO Terms for Motor Stereotypies

Sources for Motor Stereotypies

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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