Aliases & Classifications for Mucinoses

MalaCards integrated aliases for Mucinoses:

Name: Mucinoses 12 43 15 71

External Ids:

Disease Ontology 12 DOID:3141
MeSH 43 D017520
SNOMED-CT 67 11528001
UMLS 71 C0162855

Summaries for Mucinoses

Disease Ontology : 12 A connective tissue disease characterized by accumulation of glycosaminoglycan located in the dermal tissue.

MalaCards based summary : Mucinoses is related to scleredema adultorum and scleromyxedema. An important gene associated with Mucinoses is CHST11 (Carbohydrate Sulfotransferase 11). The drugs Histamine and Tranilast have been mentioned in the context of this disorder. Affiliated tissues include dermal tissue, thyroid and skin.

Wikipedia : 74 Mucinoses are a group of cutaneous diseases caused by fibroblasts producing abnormally large amounts of... more...

Related Diseases for Mucinoses

Graphical network of the top 20 diseases related to Mucinoses:



Diseases related to Mucinoses

Symptoms & Phenotypes for Mucinoses

Drugs & Therapeutics for Mucinoses

Drugs for Mucinoses (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Histamine Approved, Investigational Early Phase 1 51-45-6 774
2
Tranilast Investigational Early Phase 1 53902-12-8 93543
3 Analgesics, Non-Narcotic Early Phase 1
4 Histamine Antagonists Early Phase 1
5 Hormones Early Phase 1
6 Analgesics Early Phase 1
7 Anti-Allergic Agents Early Phase 1
8 Platelet Aggregation Inhibitors Early Phase 1
9
Histamine Phosphate Early Phase 1 51-74-1 65513
10 Histamine H1 Antagonists Early Phase 1
11 Neurotransmitter Agents Early Phase 1
12 Calcium, Dietary Early Phase 1
13 Antirheumatic Agents Early Phase 1
14 Anti-Inflammatory Agents Early Phase 1
15 Anti-Inflammatory Agents, Non-Steroidal Early Phase 1
16 calcium channel blockers Early Phase 1
17
Calcium Nutraceutical Early Phase 1 7440-70-2 271

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase I/II Open Label Study in MPS IIIB Subjects to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 Administered Intravenously Completed NCT02324049 Phase 1, Phase 2 SBC-103
2 A Clinical Study of Tranilast in the Treatment of Mucinoses Not yet recruiting NCT03490708 Early Phase 1 Tranilast

Search NIH Clinical Center for Mucinoses

Cochrane evidence based reviews: mucinoses

Genetic Tests for Mucinoses

Anatomical Context for Mucinoses

The Foundational Model of Anatomy Ontology organs/tissues related to Mucinoses:

19
Dermal Tissue

MalaCards organs/tissues related to Mucinoses:

40
Thyroid, Skin, Lung

Publications for Mucinoses

Articles related to Mucinoses:

(show top 50) (show all 74)
# Title Authors PMID Year
1
Primary paediatric cutaneous mucinoses. 61
30977896 2020
2
Classifying primary paediatric cutaneous mucinoses. 61
31468512 2020
3
Clinical, dermoscopic, and histologic aspects of two cases of cutaneous focal mucinosis. 61
31365664 2019
4
Lichen myxedematosus: a rare group of cutaneous mucinosis. 61
31644623 2019
5
Discrete Papular Lichen Myxedematosus and Scleromyxedema with Hypothyroidism: A Report of Two Cases. 61
31011315 2019
6
Cutaneous mucinosis of infancy: report of a rare case and review of the literature. 61
30677812 2018
7
Obesity-Associated Lymphedematous Mucinosis: Two Further Cases and Review of the Literature. 61
29719826 2018
8
Trauma-induced Focal Nodular Mucinoses: A Rare Entity. 61
29441300 2018
9
Review of Primary Cutaneous Mucinoses in Nonlupus Connective Tissue Diseases. 61
28673091 2018
10
Cutaneous Manifestations of Scleroderma and Scleroderma-Like Disorders: a Comprehensive Review. 61
28712039 2017
11
Solitary cutaneous focal mucinosis: A clinicopathological study of 11 cases of soft fibroma-like cutaneous mucinous lesions. 61
27450934 2017
12
Scleromyxedema without Paraproteinemia: Treatment with Thalidomide and Prednisolone. 61
27990110 2016
13
Atypical scleromyxedema presenting with cutaneous and cardiovascular manifestations. 61
27698568 2016
14
Transepidermal elimination of mucin is a very common but not yet reported phenomenon in digital myxoid cysts: a study of 35 cases. 61
26264152 2015
15
[Monoclonal immunoglobulin (M-Ig) and skin diseases from the group of mucinoses--scleredema adultorum Buschke and scleromyxedema. Description of four cases and an overview of therapies]. 61
26806503 2015
16
[Dermatological manifestations of monoclonal gammopathies: contribution of cutaneous histopathology]. 61
26188671 2015
17
Periadnexal mucin as an additional histopathologic feature of chronic eczematous dermatitis. 61
25834351 2015
18
Discrete papular lichen myxedematosus: a rare entity or an under- diagnosed disease? 61
25815101 2014
19
Pretibial mucinosis in a patient without Graves disease. 61
22372171 2011
20
Identification of specific chondroitin sulfate species in cutaneous autoimmune disease. 61
21804080 2011
21
Discrete papular dermal mucinosis with Hashimoto thyroiditis: a case report. 61
21488572 2011
22
Cutaneous focal mucinosis arising from the chin. 61
20856067 2010
23
Dermal mucinosis as a sign of venous insufficiency. 61
19614999 2010
24
Discrete papular lichen myxoedematosus: a rare subtype of cutaneous mucinosis. 61
19486062 2009
25
Cutaneous mucinosis associated with dermatomyositis and nephrogenic fibrosing dermopathy: fibroblast hyaluronan synthesis and the effect of patient serum. 61
17300236 2007
26
[Acral persistent papular mucinosis]. 61
17067531 2006
27
Reticular erythematous mucinosis (REM) with telangiectasias associated with essential thrombocytosis and lung carcinoma. 61
15908303 2005
28
Buschke's scleredema and concomitant diseases: report of five cases and literature review. 61
16146615 2005
29
Focal mucinosis: clinical and histological features of an unusual condition. 61
12803795 2003
30
Diffuse cutaneous mucinoses. 61
12170882 2002
31
[Scleredema adultorum in secondary hyperparathyroidism]. 61
11963192 2002
32
Cutaneous focal mucinosis: a case report. 61
11860567 2002
33
Cutaneous mucinoses complicating interferon beta-1b therapy. 61
11844903 2002
34
Cutaneous mucinoses: microscopic criteria for diagnosis. 61
11391115 2001
35
Cutaneous lupus erythematosus. 61
11308132 2001
36
Lipedematous alopecia: a clinicopathologic, histologic and ultrastructural study. 61
10660132 2000
37
Cutaneous mucinoses and HIV infection. 61
9990377 1998
38
Reticulate postinflammatory hyperpigmentation with band-like mucin deposition. 61
9865868 1998
39
Type I and type III collagens in cutaneous mucinosis. 61
9504668 1998
40
Self-healing infantile familial cutaneous mucinosis. 61
9436845 1997
41
[Cutaneous mucinoses]. 61
8668693 1996
42
[Persistent acral papulous mucinosis]. 61
8763749 1996
43
Self-healing juvenile cutaneous mucinosis. 61
7726590 1995
44
[Mucinoses]. 61
7638361 1995
45
[Quadri-chromic staining in routine cutaneous histopathology (hematoxylin, eosin, saffron and astra blue)]. 61
8729819 1995
46
Papulonodular dermal mucinosis in systemic lupus erythematosus. 61
8064739 1994
47
Self-healing localized cutaneous mucinosis. 61
8003801 1994
48
The dermal mucinoses. 61
7694631 1993
49
[Cutaneous mucinosis]. 61
8338331 1993
50
Cutaneous toxic mucinoses. 61
1583189 1992

Variations for Mucinoses

Expression for Mucinoses

Search GEO for disease gene expression data for Mucinoses.

Pathways for Mucinoses

GO Terms for Mucinoses

Cellular components related to Mucinoses according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratin filament GO:0045095 8.62 KRT74 KRT71

Biological processes related to Mucinoses according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 8.62 KRT74 KRT71

Sources for Mucinoses

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....