MCID: MCN020
MIFTS: 28

Mucinous Cystadenocarcinoma of Pancreas

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Rare diseases
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Aliases & Classifications for Mucinous Cystadenocarcinoma of Pancreas

MalaCards integrated aliases for Mucinous Cystadenocarcinoma of Pancreas:

Name: Mucinous Cystadenocarcinoma of Pancreas 11
Pancreatic Mucinous Cystadenocarcinoma 11 58 71
Mucinous Cystadenocarcinoma of the Pancreas 58 14
Pancreatic Colloid Cystadenocarcinoma 11

Characteristics:


Prevelance:

Mucinous Cystadenocarcinoma of the Pancreas: <1/1000000 58

Age Of Onset:

Mucinous Cystadenocarcinoma of the Pancreas: Adult 58

Classifications:

Orphanet: 58  
Rare gastroenterological diseases


External Ids:

Disease Ontology 11 DOID:7234
NCIt 49 C5713
SNOMED-CT 68 785879009
ICD10 via Orphanet 32 C25.0 C25.1 C25.2 more
UMLS via Orphanet 72 C2063873
Orphanet 58 ORPHA424053
UMLS 71 C1335308 C2063873

Summaries for Mucinous Cystadenocarcinoma of Pancreas

Orphanet: 58 A rare, epithelial tumor of the pancreas characterized, histologically, by columnar, mucin-producing epithelium associated with ovarian-type subepithelial stroma, which does not communicate with the pancreatic ductal system, most frequently localized to the body or tail of the pancreas. Clinically, small tumors (<3 cm) are usually asymptomatic, while large tumors typically present obstructive jaundice, a palpable abdominal mass, and may associate portal hypertension, hemobilia and diabetes mellitus.

MalaCards based summary: Mucinous Cystadenocarcinoma of Pancreas, also known as pancreatic mucinous cystadenocarcinoma, is related to cystadenocarcinoma and appendix adenocarcinoma. An important gene associated with Mucinous Cystadenocarcinoma of Pancreas is MIR224 (MicroRNA 224). The drugs Ethanol and Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include pancreas, lymph node and ovary.

Disease Ontology: 11 A pancreatic cystadenocarinoma that is characterized by histological characteristics of columnar, mucin-producing epithelium associated with ovarian-type subepithelial stroma, which does not communicate with the pancreatic ductal system, most frequently localized to the body or tail of the pancreas.

Related Diseases for Mucinous Cystadenocarcinoma of Pancreas

Diseases related to Mucinous Cystadenocarcinoma of Pancreas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Related Disease Score Top Affiliating Genes
1 cystadenocarcinoma 30.9 MIR224 CEACAM5
2 appendix adenocarcinoma 30.6 SATB2 CEACAM5
3 cystadenoma 30.0 MUC6 CEACAM5
4 pancreatic cystadenocarcinoma 29.4 SATB2 MUC6 MIR224 CWC22 CEACAM5
5 mucinous cystadenocarcinoma 10.5
6 pancreatic cancer 10.4
7 carcinoid tumors, intestinal 10.2
8 cystic fibrosis 10.2
9 type 1 diabetes mellitus 10.2
10 coronary heart disease 1 10.2
11 endometrial cancer 10.2
12 rhabdoid tumor predisposition syndrome 1 10.2
13 deficiency anemia 10.2
14 zollinger-ellison syndrome 10.2
15 lipoid nephrosis 10.2
16 cholestasis 10.2
17 obstructive jaundice 10.2
18 adenocarcinoma 10.2
19 duodenal obstruction 10.2
20 rhabdoid cancer 10.2
21 kidney rhabdoid cancer 10.2
22 somatostatinoma 10.2
23 back pain 10.2
24 gastrointestinal stromal tumor 10.1
25 portal hypertension 10.1
26 mucinous ovarian cystadenoma 10.1
27 rare tumor 10.1
28 gastric cancer 10.1
29 gastric ulcer 10.1
30 splenic infarction 10.1
31 pancreatic ductal adenocarcinoma 10.1
32 pancreatic adenocarcinoma 10.1
33 papillary serous adenocarcinoma 10.0 MIR224 CEACAM5
34 appendiceal neoplasm 10.0 SATB2 CEACAM5
35 krukenberg carcinoma 10.0 SATB2 CEACAM5
36 ovarian mucinous adenocarcinoma 10.0 SATB2 CEACAM5
37 urinary bladder villous adenoma 9.9 MUC6 CEACAM5
38 villous adenoma 9.9 MUC6 CEACAM5
39 gallbladder carcinoma in situ 9.9 MUC6 CEACAM5
40 biliary papillomatosis 9.9 MUC6 CEACAM5
41 pancreatic serous cystadenoma 9.9 MUC6 CEACAM5
42 mucinous intrahepatic cholangiocarcinoma 9.9 MUC6 CEACAM5
43 bile duct cystadenocarcinoma 9.9 MUC6 CEACAM5
44 mucinous adenocarcinoma 9.9 MUC6 CEACAM5
45 pancreatic signet ring cell adenocarcinoma 9.8 MUC6 CEACAM5
46 signet ring cell adenocarcinoma 9.8 MUC6 CEACAM5
47 acute cholangitis 9.8 MUC6 CEACAM5
48 hepatoid adenocarcinoma 9.8 MUC6 CEACAM5
49 biliary tract benign neoplasm 9.8 MUC6 CEACAM5
50 microcystic adenoma 9.8 MUC6 CEACAM5

Graphical network of the top 20 diseases related to Mucinous Cystadenocarcinoma of Pancreas:



Diseases related to Mucinous Cystadenocarcinoma of Pancreas

Symptoms & Phenotypes for Mucinous Cystadenocarcinoma of Pancreas

Drugs & Therapeutics for Mucinous Cystadenocarcinoma of Pancreas

Drugs for Mucinous Cystadenocarcinoma of Pancreas (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 1 64-17-5 702
2
Paclitaxel Approved, Vet_approved Phase 1 33069-62-4 36314
3 Anti-Bacterial Agents Phase 1
4 Albumin-Bound Paclitaxel Phase 1
5 Anti-Infective Agents Phase 1
6 Antimitotic Agents Phase 1
7 Tubulin Modulators Phase 1
8 Antibiotics, Antitubercular Phase 1
9 Anti-Infective Agents, Local Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 EUS Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm Terminated NCT01525706 Phase 1 Ethanol and Paclitaxel Injection

Search NIH Clinical Center for Mucinous Cystadenocarcinoma of Pancreas

Genetic Tests for Mucinous Cystadenocarcinoma of Pancreas

Anatomical Context for Mucinous Cystadenocarcinoma of Pancreas

Organs/tissues related to Mucinous Cystadenocarcinoma of Pancreas:

MalaCards : Pancreas, Lymph Node, Ovary, Liver, Breast

Publications for Mucinous Cystadenocarcinoma of Pancreas

Articles related to Mucinous Cystadenocarcinoma of Pancreas:

(show top 50) (show all 73)
# Title Authors PMID Year
1
A case of pancreatic mucinous cystadenocarcinoma with malignant ascites without recurrence for more than 8 years after surgery. 62
35546381 2022
2
Cancer-specific survival and metastasis in pancreatic mucinous cystadenocarcinoma: A SEER-based cohort study. 62
36338678 2022
3
Dramatic Response to Carboplatin Plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis. 62
33814494 2021
4
Mucinous cystadenocarcinoma of pancreas mimicking gastrointestinal stromal tumor of stomach: Case report. 62
34343789 2021
5
miR‑224‑5p regulates the proliferation, migration and invasion of pancreatic mucinous cystadenocarcinoma by targeting PTEN. 62
33760113 2021
6
Breast Metastases Secondary to Primary Pancreatic Mucinous Cystadenocarcinoma: A Case Report. 62
33370036 2021
7
Pancreatic mucinous cystadenocarcinoma in a patient harbouring BRCA1 germline mutation effectively treated with olaparib: A case report. 62
33362915 2020
8
Autophagy promotes malignant migration and invasion via miR-224-5p/BCL2 in pancreatic mucinous cystadenocarcinoma MCC1 cells. 62
33029204 2020
9
Mucinous Cystadenocarcinoma of the Pancreas with Cyst Infection in a Male Patient. 62
32999265 2020
10
Metastatic mucinous cystadenocarcinoma of the pancreas presenting as intractable back pain. 62
31791983 2019
11
Contrast-enhanced Harmonic EUS Imaging of Pancreatic Mucinous Cystadenocarcinoma. 62
29780137 2018
12
Pancreatic pseudocyst or mucinous cystadenocarcinoma of pancreas? A diagnostic dilemma. 62
28396777 2017
13
Pancreatic mucinous cystadenocarcinoma: Epidemiology and outcomes. 62
27638187 2016
14
Mucinous cystadenocarcinoma of the pancreas with anaplastic carcinoma: A case report and review of the literature. 62
27073646 2016
15
Extragastroesophageal Malignancy-Associated Secondary Achalasia: A Rare Association of Pancreatic Cancer Rendering Alarm Manifestation. 62
26240808 2015
16
Atypical presentation of gastrointestinal stromal tumor masquerading as a large duodenal cyst: A case report. 62
25768277 2015
17
[A case of a patient with giant mucinous cystadenocarcinoma who presented with abdominal pain]. 62
24394137 2013
18
A case of mucinous cystadenocarcinoma of the pancreas with spontaneous rupture diagnosed by endoscopic retrograde pancreatography. 62
23526506 2013
19
Pancreatic Mucinous Cystadenocarcinoma Presenting with Splenic Infarction in a Young Female. 62
22222557 2012
20
Mucinous cystadenocarcinoma of the pancreas - outcome following different modes of treatment. 62
24713784 2011
21
[Mucinous cystic neoplasm of the pancreas associated with pregnancy: report of two cases]. 62
21071901 2010
22
Total pancreaticoduodenectomy and segmental resection of superior mesenteric vein-portal vein confluence with autologous splenic vein graft in mucinous cystadenocarcinoma of the pancreas. 62
21068503 2010
23
A case of advanced mucinous cystadenocarcinoma of the pancreas with peritoneal dissemination responding to gemcitabine. 62
19542723 2009
24
[Mucinous cystadenocarcinoma of pancreas]. 62
21138674 2009
25
Mucinous cystadenocarcinoma of the pancreas diagnosed in postpartum. 62
17530280 2007
26
[Pancreatic mucinous cystadenocarcinoma]. 62
17553411 2007
27
Metastatic mucinous cystic adenocarcinoma of the pancreas presenting as Sister Mary Joseph's nodule. 62
17495365 2007
28
An extremely rare cause of acute abdomen in pregnancy: ruptured pancreatic mucinous cystadenocarcinoma. 62
17446849 2007
29
Mucinous cystadenocarcinoma of the pancreas developing during hormone replacement therapy. 62
17372823 2007
30
Mucinous cystadenocarcinoma of the pancreas during pregnancy. 62
17446848 2007
31
Mixed serous cystadenoma with mucinous cystadenoma of the pancreas. 62
15968256 2005
32
Mucinous cystadenocarcinoma of the pancreas in an adolescent with cystic fibrosis. 62
16010483 2005
33
Metastatic lymph node impostor in pancreatic cystadenocarcinoma. 62
15767737 2005
34
Huge mucinous cystadenoma of the pancreas developing during pregnancy: a case report. 62
15714143 2005
35
Osteoclast-like giant cell tumor in mucinous cystadenocarcinoma of the pancreas: an immunohistochemical and molecular analysis. 62
15734212 2005
36
[Fluorodeoxiglucose F18 positron emission tomography imaging (F18FDG) for the assessment of rising levels of serum CA 19-9 in pancreatic mucinous cystadenocarcinoma. Report of one case]. 62
15376572 2004
37
A case of triple synchronous cancers occurring in the gallbladder, common bile duct, and pancreas. 62
12560930 2003
38
Intraductal papillary mucinous cystadenocarcinoma of the pancreas with intrapancreatic perineural invasion. 62
11893941 2002
39
[A case of pseudomyxoma peritonei with a pancreatic cancer treated by the intraperitoneal administration of cisplatinum]. 62
11708005 2001
40
An osteoclast-like giant cell tumor pattern in a mucinous cystadenocarcinoma of the pancreas with lymph node metastasis in a patient surviving over 10 years. 62
11407484 2001
41
"Ductectatic" mucinous cystadenocarcinoma of the pancreas: a case report, 5-year follow-up period. 62
11149050 2000
42
Simultaneous mucinous cystadenoma of ovary and mucinous cystadenocarcinoma of pancreas. 62
11185714 2000
43
Unusual presentation of pancreatic mucinous cystadenocarcinoma by spontaneous splenic rupture. 62
11155016 2000
44
[A case report of pancreatic mucinous cystadenocarcinoma with penetration to the stomach]. 62
10396942 1999
45
[A pancreatic mucinous cystadenocarcinoma with diffuse spread]. 62
10231355 1999
46
Gastroparesis after celiac plexus block. 62
9820401 1998
47
Ductectatic mucinous cystadenocarcinoma of the pancreas: a rare variant. 62
9951933 1998
48
Ovarian-like stroma in an invasive mucinous cystadenocarcinoma of the pancreas positive for inhibin. A hint concerning its possible histogenesis. 62
9645445 1998
49
Anaplastic carcinoma showing rhabdoid features combined with mucinous cystadenocarcinoma of the pancreas. 62
9341593 1997
50
Hepatobiliary and pancreatic mucinous cystadenocarcinomas with mesenchymal stroma: analysis of estrogen receptors/progesterone receptors and expression of tumor-associated antigens. 62
9110301 1997

Variations for Mucinous Cystadenocarcinoma of Pancreas

Expression for Mucinous Cystadenocarcinoma of Pancreas

Search GEO for disease gene expression data for Mucinous Cystadenocarcinoma of Pancreas.

Pathways for Mucinous Cystadenocarcinoma of Pancreas

GO Terms for Mucinous Cystadenocarcinoma of Pancreas

Sources for Mucinous Cystadenocarcinoma of Pancreas

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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