MCID: MCN023
MIFTS: 38

Mucinous Lung Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Mucinous Lung Adenocarcinoma

MalaCards integrated aliases for Mucinous Lung Adenocarcinoma:

Name: Mucinous Lung Adenocarcinoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0080303

Summaries for Mucinous Lung Adenocarcinoma

Disease Ontology : 12 A lung adenocarcinoma with tumor cells floating in pools of mucin that distend alveolar spaces.

MalaCards based summary : Mucinous Lung Adenocarcinoma is related to lung cancer susceptibility 3 and adenocarcinoma. An important gene associated with Mucinous Lung Adenocarcinoma is NRG1 (Neuregulin 1), and among its related pathways/superpathways are ERK Signaling and GPCR Pathway. Affiliated tissues include lung, colon and ovary, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Mucinous Lung Adenocarcinoma

Diseases related to Mucinous Lung Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 lung cancer susceptibility 3 30.1 ALK EGFR ERBB2 ERBB3 HRAS IGF1R
2 adenocarcinoma 30.0 ALK EGFR ERBB2 ERBB3 FGFR1 HRAS
3 breast intraductal proliferative lesion 10.3 EGFR ERBB2
4 progesterone-receptor negative breast cancer 10.2 EGFR ERBB2
5 breast scirrhous carcinoma 10.2 EGFR ERBB2
6 luminal breast carcinoma 10.2 EGFR ERBB2 ERBB3
7 clivus chordoma 10.2 ERBB3 FGFR1 IGF1R
8 sigmoid neoplasm 10.2 HRAS KRAS
9 primary peritoneal carcinoma 10.2 CXCL10 EGFR ERBB2
10 large cell carcinoma 10.2 EGFR FGFR1 ROS1
11 breast carcinoma in situ 10.2 EGFR ERBB2 FGFR1
12 apocrine adenoma 10.1 HRAS KRAS
13 encephalocraniocutaneous lipomatosis 10.1 FGFR1 KRAS
14 opsoclonus-myoclonus syndrome 10.1 CXCL10 CXCR3
15 paronychia 10.1 EGFR HRAS KRAS
16 periampullary adenoma 10.1 HRAS KRAS
17 endometrial adenocarcinoma 10.1 EGFR ERBB2 KRAS
18 schimmelpenning-feuerstein-mims syndrome 10.1 HRAS KRAS
19 carcinosarcoma 10.1 ERBB2 HRAS KRAS
20 lung benign neoplasm 10.1 EGFR HRAS KRAS
21 ovary adenocarcinoma 10.1 ERBB2 HRAS KRAS
22 stomach disease 10.1 AREG EGFR ERBB2
23 bile duct cysts 10.1 HRAS KRAS
24 female reproductive system disease 10.1 AREG EGFR ERBB2
25 reproductive system disease 10.1 AREG EGFR ERBB2
26 mucoepidermoid carcinoma 10.1 AREG EGFR ERBB2
27 colorectal adenocarcinoma 10.1 EGFR HRAS KRAS
28 breast squamous cell carcinoma 10.1 EGFR ERBB2
29 ovarian cancer 1 10.1 AREG ERBB2 KRAS
30 oral cavity cancer 10.1 AREG EGFR ERBB2
31 lung adenoid cystic carcinoma 10.1 ALK HRAS KRAS
32 mucinous adenocarcinoma 10.1 ALK EGFR KRAS NRG1
33 uterine carcinosarcoma 10.1 EGFR ERBB2 ERBB3 HRAS
34 transitional cell carcinoma 10.0 EGFR ERBB2 ERBB3 HRAS
35 cholangiocarcinoma 10.0 EGFR ERBB2 KRAS ROS1
36 aggressive digital papillary adenocarcinoma 10.0 HRAS KRAS
37 intestinal benign neoplasm 10.0 AREG HRAS KRAS
38 acneiform dermatitis 10.0 EGFR ERBB2 HRAS KRAS
39 breast adenocarcinoma 10.0 EGFR ERBB2 KRAS
40 pancreas disease 10.0 AREG HRAS KRAS
41 core binding factor acute myeloid leukemia 10.0 HRAS KRAS TLE1
42 bladder urothelial carcinoma 10.0 ERBB2 FGFR1 HRAS KRAS
43 medulloblastoma 10.0 EGFR ERBB2 ERBB3 FGFR1 IGF1R
44 colonic disease 10.0 AREG EGFR HRAS KRAS
45 intestinal disease 10.0 AREG EGFR HRAS KRAS
46 malignant ovarian surface epithelial-stromal neoplasm 10.0 AREG ERBB2 HRAS KRAS
47 ovary epithelial cancer 10.0 AREG ERBB2 HRAS KRAS
48 appendix disease 9.9 HRAS KRAS
49 squamous cell carcinoma, head and neck 9.9 AREG EGFR ERBB2 ERBB3 HRAS
50 esophageal cancer 9.9 EGFR ERBB2 HRAS IGF1R KRAS

Graphical network of the top 20 diseases related to Mucinous Lung Adenocarcinoma:



Diseases related to Mucinous Lung Adenocarcinoma

Symptoms & Phenotypes for Mucinous Lung Adenocarcinoma

GenomeRNAi Phenotypes related to Mucinous Lung Adenocarcinoma according to GeneCards Suite gene sharing:

26 (show top 50) (show all 61)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 10.94 EGFR HRAS KRAS TRIM24
2 Decreased viability GR00106-A-0 10.94 KRAS ERBB3
3 Decreased viability GR00221-A-1 10.94 EGFR HRAS KRAS FGFR1 IGF1R ROS1
4 Decreased viability GR00221-A-2 10.94 HRAS KRAS ERBB3 FGFR1 IGF1R ROS1
5 Decreased viability GR00221-A-3 10.94 HRAS IGF1R
6 Decreased viability GR00221-A-4 10.94 EGFR ERBB3 ALK
7 Decreased viability GR00301-A 10.94 KRAS ERBB3 IGF1R
8 Decreased viability GR00342-S-1 10.94 ROS1
9 Decreased viability GR00342-S-2 10.94 ERBB3 IGF1R
10 Decreased viability GR00342-S-3 10.94 ERBB3
11 Decreased viability GR00381-A-1 10.94 KRAS TRIM24
12 Decreased viability GR00402-S-2 10.94 EGFR HRAS KRAS TRIM24 ERBB3 FGFR1
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 10.45 TLE1
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-112 10.45 TRIM24
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 10.45 ERBB3
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-142 10.45 TRIM24
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 10.45 IGF1R
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-148 10.45 ERBB2
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 10.45 IGF1R
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-173 10.45 TRIM24
21 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 10.45 TRIM24
22 Decreased shRNA abundance (Z-score < -2) GR00366-A-204 10.45 TRIM24
23 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 10.45 ERBB3
24 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 10.45 TRIM24
25 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 10.45 ERBB3
26 Decreased shRNA abundance (Z-score < -2) GR00366-A-55 10.45 TRIM24
27 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 10.45 ERBB2 ERBB3 IGF1R TLE1 TRIM24
28 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 10.45 TLE1
29 Decreased shRNA abundance (Z-score < -2) GR00366-A-87 10.45 ERBB2 IGF1R
30 Decreased cell migration GR00055-A-1 9.91 ALK EGFR HRAS IGF1R KRAS TRIM24
31 Condensed cis-Golgi GR00365-A 9.85 CXCL10 ERBB3 FGFR1 IGF1R ROS1
32 Decreased substrate adherent cell growth GR00193-A-1 9.85 ERBB3 ROS1
33 Decreased substrate adherent cell growth GR00193-A-2 9.85 ALK EGFR ERBB3 ROS1
34 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.84 IGF1R
35 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.84 EGFR
36 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.84 ERBB3
37 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.84 EGFR
38 Increased shRNA abundance (Z-score > 2) GR00366-A-123 9.84 TRIM24
39 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.84 TRIM24
40 Increased shRNA abundance (Z-score > 2) GR00366-A-127 9.84 IGF1R TRIM24
41 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.84 ERBB3
42 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.84 ERBB2
43 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.84 ERBB2
44 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.84 ERBB2
45 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.84 IGF1R
46 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.84 IGF1R
47 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.84 EGFR
48 Increased shRNA abundance (Z-score > 2) GR00366-A-198 9.84 ERBB3
49 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.84 IGF1R
50 Increased shRNA abundance (Z-score > 2) GR00366-A-207 9.84 ERBB2

MGI Mouse Phenotypes related to Mucinous Lung Adenocarcinoma:

46 (show all 13)
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.29 CD74 CXCL10 CXCR3 EGFR ERBB2 ERBB3
2 homeostasis/metabolism MP:0005376 10.25 ALK AREG CXCL10 CXCR3 EGFR ERBB2
3 cardiovascular system MP:0005385 10.22 AREG CXCL10 CXCR3 EGFR ERBB2 ERBB3
4 growth/size/body region MP:0005378 10.2 ALK AREG CD74 EGFR ERBB2 ERBB3
5 digestive/alimentary MP:0005381 10.15 AREG EGFR ERBB2 ERBB3 FGFR1 HRAS
6 endocrine/exocrine gland MP:0005379 10.13 ALK AREG EGFR ERBB2 ERBB3 FGFR1
7 mortality/aging MP:0010768 10.13 ALK AREG CD74 CXCL10 CXCR3 EGFR
8 immune system MP:0005387 10.1 AREG CD74 CXCL10 CXCR3 EGFR ERBB3
9 integument MP:0010771 10.02 ALK AREG EGFR ERBB2 ERBB3 FGFR1
10 neoplasm MP:0002006 9.96 ALK CXCR3 EGFR ERBB2 ERBB3 HRAS
11 reproductive system MP:0005389 9.76 ALK AREG EGFR ERBB2 FGFR1 IGF1R
12 respiratory system MP:0005388 9.56 ALK CXCR3 EGFR ERBB2 ERBB3 HRAS
13 skeleton MP:0005390 9.23 ALK CD74 EGFR ERBB2 FGFR1 HRAS

Drugs & Therapeutics for Mucinous Lung Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Mucinous Lung Adenocarcinoma

Genetic Tests for Mucinous Lung Adenocarcinoma

Anatomical Context for Mucinous Lung Adenocarcinoma

MalaCards organs/tissues related to Mucinous Lung Adenocarcinoma:

41
Lung, Colon, Ovary, Prostate, Pancreas, Thyroid, Myeloid

Publications for Mucinous Lung Adenocarcinoma

Articles related to Mucinous Lung Adenocarcinoma:

# Title Authors Year
1
Mucinous Lung Adenocarcinoma Metastasis to Testis in a 29 Year Old-A Case Report. ( 29548865 )
2018
2
EGFR and HER3 signaling blockade in invasive mucinous lung adenocarcinoma harboring an NRG1 fusion. ( 30268483 )
2018
3
Pro-tumoural CXCL10/CXCR3-A autocrine loop in invasive mucinous lung adenocarcinoma. ( 28845427 )
2017
4
Pneumonic-type mucinous lung adenocarcinoma diagnosed by transbronchial cryobiopsy. ( 28261482 )
2017
5
NRG1 fusion in a French cohort of invasive mucinous lung adenocarcinoma. ( 27770508 )
2016
6
Druggable oncogene fusions in invasive mucinous lung adenocarcinoma. ( 24727320 )
2014
7
Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma. ( 21598249 )
2011
8
Resection of mucinous lung adenocarcinoma presenting with intractable bronchorrhea. ( 20357626 )
2010

Variations for Mucinous Lung Adenocarcinoma

Expression for Mucinous Lung Adenocarcinoma

Search GEO for disease gene expression data for Mucinous Lung Adenocarcinoma.

Pathways for Mucinous Lung Adenocarcinoma

Pathways related to Mucinous Lung Adenocarcinoma according to GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.9 ALK AREG CXCL10 CXCR3 EGFR ERBB2
2
Show member pathways
13.8 ALK AREG EGFR ERBB2 ERBB3 FGFR1
3
Show member pathways
13.75 ALK CXCL10 CXCR3 EGFR ERBB2 ERBB3
4
Show member pathways
13.63 ALK AREG EGFR ERBB2 ERBB3 FGFR1
5
Show member pathways
13.61 ALK AREG EGFR ERBB2 ERBB3 FGFR1
6
Show member pathways
13.51 EGFR ERBB2 ERBB3 FGFR1 HRAS KRAS
7
Show member pathways
13.51 CD74 EGFR ERBB2 ERBB3 FGFR1 HRAS
8
Show member pathways
13.43 CXCL10 EGFR ERBB2 ERBB3 FGFR1 HRAS
9
Show member pathways
13.37 AREG CXCL10 CXCR3 EGFR ERBB2 FGFR1
10
Show member pathways
13.33 ALK AREG EGFR ERBB2 ERBB3 FGFR1
11
Show member pathways
13.29 AREG EGFR ERBB2 ERBB3 HRAS IGF1R
12
Show member pathways
13.28 ALK AREG CXCL10 CXCR3 EGFR ERBB2
13
Show member pathways
13.2 ALK AREG EGFR ERBB2 ERBB3 FGFR1
14
Show member pathways
13.15 AREG EGFR FGFR1 HRAS IGF1R KRAS
15
Show member pathways
13.15 ALK AREG EGFR FGFR1 HRAS IGF1R
16
Show member pathways
13.1 ALK EGFR ERBB2 ERBB3 FGFR1 HRAS
17
Show member pathways
13.1 AREG EGFR ERBB2 ERBB3 FGFR1 HRAS
18
Show member pathways
12.97 EGFR ERBB2 ERBB3 HRAS IGF1R KRAS
19
Show member pathways
12.97 EGFR ERBB2 ERBB3 FGFR1 HRAS IGF1R
20
Show member pathways
12.97 AREG EGFR ERBB2 FGFR1 HRAS IGF1R
21 12.94 ALK EGFR ERBB2 FGFR1 HRAS IGF1R
22
Show member pathways
12.91 EGFR ERBB2 HRAS IGF1R KRAS
23
Show member pathways
12.85 EGFR ERBB2 FGFR1 HRAS IGF1R KRAS
24 12.85 AREG EGFR ERBB2 ERBB3 FGFR1 HRAS
25
Show member pathways
12.84 EGFR ERBB2 ERBB3 FGFR1 HRAS KRAS
26
Show member pathways
12.78 EGFR FGFR1 HRAS IGF1R KRAS
27
Show member pathways
12.78 ALK EGFR ERBB2 ERBB3 FGFR1 HRAS
28
Show member pathways
12.77 ERBB2 ERBB3 HRAS KRAS NRG1
29
Show member pathways
12.64 AREG EGFR ERBB2 ERBB3 HRAS KRAS
30 12.59 EGFR ERBB2 ERBB3 HRAS KRAS
31
Show member pathways
12.58 AREG EGFR ERBB2 ERBB3 HRAS KRAS
32
Show member pathways
12.52 EGFR ERBB2 ERBB3 FGFR1 HRAS IGF1R
33
Show member pathways
12.44 EGFR ERBB2 ERBB3 HRAS IGF1R NRG1
34
Show member pathways
12.43 EGFR ERBB2 ERBB3 HRAS KRAS NRG1
35
Show member pathways
12.42 EGFR HRAS IGF1R KRAS
36
Show member pathways
12.38 AREG EGFR FGFR1 IGF1R KRAS NRG1
37
Show member pathways
12.34 AREG EGFR FGFR1 HRAS KRAS
38 12.34 EGFR ERBB2 ERBB3 FGFR1 HRAS IGF1R
39
Show member pathways
12.3 EGFR ERBB2 ERBB3 FGFR1 HRAS IGF1R
40
Show member pathways
12.29 CD74 HRAS KRAS SLC3A2
41
Show member pathways
12.27 EGFR ERBB2 ERBB3 FGFR1 HRAS IGF1R
42 12.25 EGFR ERBB2 HRAS KRAS
43
Show member pathways
12.24 EGFR ERBB2 HRAS IGF1R NRG1
44
Show member pathways
12.23 FGFR1 HRAS KRAS TRIM24
45
Show member pathways
12.21 EGFR ERBB2 HRAS KRAS
46
Show member pathways
12.19 AREG EGFR FGFR1 HRAS KRAS NRG1
47 12.18 EGFR ERBB2 ERBB3 FGFR1 HRAS IGF1R
48 12.17 FGFR1 HRAS IGF1R KRAS
49
Show member pathways
12.16 EGFR HRAS IGF1R KRAS
50
Show member pathways
12.14 EGFR ERBB2 ERBB3 HRAS KRAS NRG1

GO Terms for Mucinous Lung Adenocarcinoma

Cellular components related to Mucinous Lung Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.97 ALK CD74 CXCR3 EGFR ERBB2 ERBB3
2 cell surface GO:0009986 9.8 AREG CD74 CXCR3 EGFR ROS1 SLC3A2
3 apical plasma membrane GO:0016324 9.76 EGFR ERBB2 ERBB3 SLC3A2
4 integral component of plasma membrane GO:0005887 9.61 ALK CXCR3 EGFR ERBB2 ERBB3 FGFR1
5 basal plasma membrane GO:0009925 9.43 EGFR ERBB2 ERBB3
6 receptor complex GO:0043235 9.17 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
7 cytoplasm GO:0005737 10.25 ALK AREG CXCR3 EGFR ERBB2 ERBB3
8 membrane GO:0016020 10.24 ALK AREG CD74 CXCR3 EGFR ERBB2
9 integral component of membrane GO:0016021 10.22 ALK AREG CD74 CXCR3 EGFR ERBB2

Biological processes related to Mucinous Lung Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 39)
# Name GO ID Score Top Affiliating Genes
1 regulation of cell proliferation GO:0042127 9.99 ALK CXCL10 EGFR ERBB3 FGFR1
2 positive regulation of protein kinase B signaling GO:0051897 9.98 EGFR ERBB2 ERBB3 FGFR1 NRG1
3 phosphatidylinositol phosphorylation GO:0046854 9.97 EGFR ERBB2 ERBB3 FGFR1 NRG1
4 positive regulation of cell migration GO:0030335 9.96 CXCL10 EGFR HRAS IGF1R
5 protein autophosphorylation GO:0046777 9.93 ALK EGFR ERBB2 FGFR1 IGF1R TRIM24
6 wound healing GO:0042060 9.91 EGFR ERBB2 ERBB3 NRG1
7 MAPK cascade GO:0000165 9.91 EGFR ERBB2 ERBB3 FGFR1 HRAS KRAS
8 positive regulation of MAPK cascade GO:0043410 9.88 CD74 EGFR ERBB2 ERBB3 FGFR1 HRAS
9 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.85 AREG CD74 NRG1
10 ERBB2 signaling pathway GO:0038128 9.84 EGFR ERBB2 ERBB3 NRG1
11 positive regulation of epithelial cell proliferation GO:0050679 9.83 EGFR ERBB2 HRAS
12 regulation of cell motility GO:2000145 9.83 EGFR ERBB2 ERBB3 NRG1
13 positive regulation of MAP kinase activity GO:0043406 9.83 EGFR ERBB2 FGFR1 HRAS KRAS
14 phosphatidylinositol 3-kinase signaling GO:0014065 9.81 ERBB2 ERBB3 IGF1R
15 peptidyl-tyrosine autophosphorylation GO:0038083 9.8 EGFR IGF1R ROS1
16 peripheral nervous system development GO:0007422 9.8 ERBB2 ERBB3 NRG1
17 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.8 ALK EGFR ERBB2 ERBB3 IGF1R ROS1
18 negative regulation of signal transduction GO:0009968 9.8 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
19 regulation of ERK1 and ERK2 cascade GO:0070372 9.79 EGFR ERBB2 ROS1
20 positive regulation of protein phosphorylation GO:0001934 9.76 ALK CD74 EGFR ERBB2 HRAS IGF1R
21 positive regulation of calcineurin-NFAT signaling cascade GO:0070886 9.68 ERBB3 NRG1
22 positive regulation of phospholipase C activity GO:0010863 9.68 FGFR1 HRAS
23 T cell chemotaxis GO:0010818 9.67 CXCL10 CXCR3
24 salivary gland morphogenesis GO:0007435 9.67 EGFR FGFR1
25 response to isolation stress GO:0035900 9.65 HRAS KRAS
26 negative regulation of ERBB signaling pathway GO:1901185 9.65 EGFR ERBB2
27 negative regulation of secretion GO:0051048 9.65 ERBB3 NRG1
28 regulation of phosphate transport GO:0010966 9.64 FGFR1 ROS1
29 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.61 ALK CD74 EGFR ERBB2 ERBB3 FGFR1
30 peptidyl-tyrosine phosphorylation GO:0018108 9.28 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
31 signal transduction GO:0007165 10.3 ALK CD74 CXCL10 CXCR3 EGFR ERBB2
32 cell differentiation GO:0030154 10.19 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
33 protein phosphorylation GO:0006468 10.15 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
34 phosphorylation GO:0016310 10.14 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
35 positive regulation of gene expression GO:0010628 10.11 ERBB2 ERBB3 HRAS KRAS NRG1 TLE1
36 negative regulation of apoptotic process GO:0043066 10.1 ALK CD74 EGFR ERBB2 ERBB3 FGFR1
37 positive regulation of cell proliferation GO:0008284 10.08 AREG CXCL10 EGFR FGFR1 HRAS IGF1R
38 cell proliferation GO:0008283 10.05 ALK AREG CD74 EGFR ERBB2 HRAS
39 cell surface receptor signaling pathway GO:0007166 10.01 CXCL10 CXCR3 EGFR ERBB2 HRAS

Molecular functions related to Mucinous Lung Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 kinase activity GO:0016301 9.95 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
2 nucleotide binding GO:0000166 9.93 EGFR ERBB2 ERBB3 FGFR1 HRAS KRAS
3 protein kinase activity GO:0004672 9.92 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
4 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.77 EGFR ERBB2 ERBB3 FGFR1 NRG1
5 protein phosphatase binding GO:0019903 9.7 EGFR ERBB2 ROS1
6 transmembrane signaling receptor activity GO:0004888 9.7 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
7 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.65 EGFR ERBB2 ERBB3 FGFR1 NRG1
8 protein tyrosine kinase activator activity GO:0030296 9.51 ERBB3 NRG1
9 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.5 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
10 ErbB-3 class receptor binding GO:0043125 9.48 ERBB2 NRG1
11 protein tyrosine kinase activity GO:0004713 9.28 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
12 transferase activity GO:0016740 10.1 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
13 ATP binding GO:0005524 10.08 ALK EGFR ERBB2 ERBB3 FGFR1 IGF1R
14 identical protein binding GO:0042802 10.03 ALK CD74 EGFR ERBB2 ERBB3 FGFR1

Sources for Mucinous Lung Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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