MCID: MCN009
MIFTS: 30

Mucinous Stomach Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Mucinous Stomach Adenocarcinoma

MalaCards integrated aliases for Mucinous Stomach Adenocarcinoma:

Name: Mucinous Stomach Adenocarcinoma 12 15
Mucinous Adenocarcinoma of the Stomach 12
Mucinous Gastric Adenocarcinoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3716
NCIt 50 C5248
UMLS 73 C1334809

Summaries for Mucinous Stomach Adenocarcinoma

MalaCards based summary : Mucinous Stomach Adenocarcinoma, also known as mucinous adenocarcinoma of the stomach, is related to adenocarcinoma and mucinous adenocarcinoma, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Mucinous Stomach Adenocarcinoma is ALDH7A1 (Aldehyde Dehydrogenase 7 Family Member A1), and among its related pathways/superpathways are Human cytomegalovirus infection and Regulation of lipid metabolism Insulin signaling-generic cascades. The drugs Antibodies and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include colon and pancreas.

Related Diseases for Mucinous Stomach Adenocarcinoma

Graphical network of the top 20 diseases related to Mucinous Stomach Adenocarcinoma:



Diseases related to Mucinous Stomach Adenocarcinoma

Symptoms & Phenotypes for Mucinous Stomach Adenocarcinoma

UMLS symptoms related to Mucinous Stomach Adenocarcinoma:


abdominal pain, dyspepsia

Drugs & Therapeutics for Mucinous Stomach Adenocarcinoma

Drugs for Mucinous Stomach Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antibodies Phase 1, Phase 2
2 Immunoglobulins Phase 1, Phase 2
3 Mitogens Phase 1, Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene Recruiting NCT03602079 Phase 1, Phase 2 A166

Search NIH Clinical Center for Mucinous Stomach Adenocarcinoma

Genetic Tests for Mucinous Stomach Adenocarcinoma

Anatomical Context for Mucinous Stomach Adenocarcinoma

MalaCards organs/tissues related to Mucinous Stomach Adenocarcinoma:

41
Colon, Pancreas

Publications for Mucinous Stomach Adenocarcinoma

Articles related to Mucinous Stomach Adenocarcinoma:

# Title Authors Year
1
Two cases of mucinous adenocarcinoma of the stomach mistaken as submucosal tumor. ( 23396274 )
2013
2
Successful transgastric drainage of a large mucinous adenocarcinoma of the stomach for palliation of malignant gastric luminal obstruction. ( 19152898 )
2009
3
Pathobiological behavior and molecular mechanism of signet ring cell carcinoma and mucinous adenocarcinoma of the stomach: a comparative study. ( 14991954 )
2004
4
A clinicopathologic study of mucinous adenocarcinoma of the stomach. ( 11706765 )
2001
5
The histogenesis of mucinous adenocarcinoma of the stomach from observations in early gastric cancer. ( 10359851 )
1999
6
Mucinous adenocarcinoma of the stomach-clinicopathological studies. ( 9029898 )
1996
7
Calcified mucinous adenocarcinoma of the stomach--the CT appearances. ( 2998700 )
1985
8
Calcified mucinous adenocarcinoma of the stomach. ( 210658 )
1978
9
A case report on calcified mucinous adenocarcinoma of the stomach. ( 4359398 )
1973
10
Calcifying mucinous adenocarcinoma of the stomach. ( 4290508 )
1967

Variations for Mucinous Stomach Adenocarcinoma

Expression for Mucinous Stomach Adenocarcinoma

Search GEO for disease gene expression data for Mucinous Stomach Adenocarcinoma.

Pathways for Mucinous Stomach Adenocarcinoma

Pathways related to Mucinous Stomach Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 25)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.68 PTEN SRC VEGFA
2
Show member pathways
12.52 PTEN SRC VEGFA
3
Show member pathways
12.5 PTEN SRC VEGFA
4
Show member pathways
12.47 PTEN SRC VEGFA
5
Show member pathways
12.37 PTEN SRC VEGFA
6
Show member pathways
12.26 PTEN SRC VEGFA
7
Show member pathways
12.08 PTEN SRC VEGFA
8
Show member pathways
11.68 SRC VEGFA
9
Show member pathways
11.67 SRC VEGFA
10 11.65 PTEN SRC
11
Show member pathways
11.63 CD8B PTEN
12 11.62 PTEN SRC
13
Show member pathways
11.55 SRC VEGFA
14 11.53 PTEN SRC
15 11.4 SRC VEGFA
16 11.24 PTEN SRC
17 11.16 SRC VEGFA
18 11.12 SRC VEGFA
19
Show member pathways
11.06 SRC VEGFA
20
Show member pathways
11.05 PTEN SRC VEGFA
21 11.02 PTEN SRC
22 10.81 CD8B PTEN
23 10.67 SRC VEGFA
24 10.54 SRC VEGFA
25 10.19 SRC VEGFA

GO Terms for Mucinous Stomach Adenocarcinoma

Biological processes related to Mucinous Stomach Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.63 PTEN SRC VEGFA
2 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.51 CD8B SRC
3 positive regulation of gene expression GO:0010628 9.5 PTEN SRC VEGFA
4 cellular response to insulin stimulus GO:0032869 9.49 PTEN SRC
5 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.48 SRC VEGFA
6 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 9.43 SRC VEGFA
7 positive regulation of MAP kinase activity GO:0043406 9.4 SRC VEGFA
8 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.37 SRC VEGFA
9 positive regulation of cell adhesion GO:0045785 9.26 SRC VEGFA
10 positive regulation of protein autophosphorylation GO:0031954 9.16 SRC VEGFA
11 negative regulation of focal adhesion assembly GO:0051895 8.96 PTEN SRC
12 cellular response to hypoxia GO:0071456 8.8 PTEN SRC VEGFA

Molecular functions related to Mucinous Stomach Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet-derived growth factor receptor binding GO:0005161 8.62 PTEN VEGFA

Sources for Mucinous Stomach Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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