Mucoepidermoid Esophageal Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Mucoepidermoid Esophageal Carcinoma

MalaCards integrated aliases for Mucoepidermoid Esophageal Carcinoma:

Name: Mucoepidermoid Esophageal Carcinoma ¹² ¹⁵

Mucoepidermoid Carcinoma of the Esophagus ¹²

Esophageal Mucoepidermoid Carcinoma ⁷³

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:4686

NCIt ⁵⁰ C5343

UMLS ⁷³ C1333461

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Summaries for Mucoepidermoid Esophageal Carcinoma

MalaCards based summary : Mucoepidermoid Esophageal Carcinoma, also known as mucoepidermoid carcinoma of the esophagus, is related to mucoepidermoid carcinoma and esophageal adenosquamous carcinoma. An important gene associated with Mucoepidermoid Esophageal Carcinoma is WWOX (WW Domain Containing Oxidoreductase), and among its related pathways/superpathways is DNA Damage. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

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Related Diseases for Mucoepidermoid Esophageal Carcinoma

Diseases related to Mucoepidermoid Esophageal Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)

#	Related Disease	Score	Top Affiliating Genes
1	mucoepidermoid carcinoma	10.2
2	esophageal adenosquamous carcinoma	10.1	CEACAM5 WWOX
3	mucositis	9.9
4	adenocarcinoma	9.9
5	gallbladder squamous cell carcinoma	9.8	CEACAM5 TP53
6	intracranial chondrosarcoma	9.8	CEACAM5 TP53
7	malignant spiradenoma	9.8	CEACAM5 TP53
8	atypical follicular adenoma	9.8	CEACAM5 TP53
9	biliary papillomatosis	9.8	CEACAM5 TP53
10	prostate squamous cell carcinoma	9.8	CEACAM5 TP53
11	ovary adenocarcinoma	9.8	CEACAM5 TP53
12	xanthogranulomatous cholecystitis	9.8	CEACAM5 TP53
13	papillary adenocarcinoma	9.8	CEACAM5 TP53
14	bile duct adenocarcinoma	9.8	CEACAM5 TP53
15	gastrointestinal system benign neoplasm	9.8	CEACAM5 TP53
16	intestinal benign neoplasm	9.8	CEACAM5 TP53
17	ovarian cancer 1	9.8	CEACAM5 TP53
18	malignant ovarian surface epithelial-stromal neoplasm	9.7	CEACAM5 TP53
19	ovary epithelial cancer	9.7	CEACAM5 TP53
20	organ system benign neoplasm	9.7	CEACAM5 TP53
21	integumentary system cancer	9.7	CEACAM5 TP53
22	lymph node cancer	9.7	TP53 WWOX
23	cystadenocarcinoma	9.7	CEACAM5 TP53
24	esophageal basaloid squamous cell carcinoma	9.7	TP53 WWOX
25	cell type benign neoplasm	9.7	CEACAM5 TP53
26	squamous cell papilloma	9.7	TP53 WWOX
27	colorectal adenocarcinoma	9.7	CEACAM5 TP53
28	esophageal disease	9.7	TP53 WWOX
29	female reproductive organ cancer	9.7	CEACAM5 TP53
30	respiratory system cancer	9.6	CEACAM5 TP53
31	rectal neoplasm	9.6	CEACAM5 TP53
32	endocrine gland cancer	9.6	CEACAM5 TP53
33	pancreas adenocarcinoma	9.6	CEACAM5 TP53
34	gallbladder cancer	9.6	CEACAM5 TP53
35	small cell cancer of the lung	9.5	CEACAM5 TP53
36	vaccinia	9.5	CEACAM5 TP53
37	adamantinoma of long bones	9.4	CEACAM5 TP53
38	lung cancer susceptibility 3	9.3	CEACAM5 TP53
39	gastric adenocarcinoma	9.2	CEACAM5 TP53
40	cell type cancer	9.1	CEACAM5 TP53 WWOX
41	gastrointestinal system cancer	9.1	CEACAM5 TP53 WWOX
42	esophageal cancer	9.0	CEACAM5 TP53 WWOX
43	cholangiocarcinoma	9.0	CEACAM5 TP53

Graphical network of the top 20 diseases related to Mucoepidermoid Esophageal Carcinoma:

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Symptoms & Phenotypes for Mucoepidermoid Esophageal Carcinoma

GenomeRNAi Phenotypes related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

²⁶ (show all 15)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-102	9.83	WWOX
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-113	9.83	WWOX
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-12	9.83	TP53
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-120	9.83	TP53
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-121	9.83	WWOX
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-129	9.83	WWOX
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-132	9.83	TP53
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-164	9.83	WWOX
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-169	9.83	TP53 WWOX
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-19	9.83	TP53 WWOX
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-190	9.83	TP53
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-35	9.83	TP53
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-39	9.83	TP53
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-63	9.83	WWOX
15	Decreased viability with paclitaxel	GR00293-A	8.96	WWOX TP53

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Drugs & Therapeutics for Mucoepidermoid Esophageal Carcinoma

Search Clinical Trials , NIH Clinical Center for Mucoepidermoid Esophageal Carcinoma

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Genetic Tests for Mucoepidermoid Esophageal Carcinoma

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Anatomical Context for Mucoepidermoid Esophageal Carcinoma

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Publications for Mucoepidermoid Esophageal Carcinoma

Articles related to Mucoepidermoid Esophageal Carcinoma:

#	Title	Authors	Year
1	Primary mucoepidermoid carcinoma of the esophagus. ( 21587086 )	Chen S....Liu D.	2011
2	Biological behavior of mucoepidermoid carcinoma of the esophagus. ( 14578940 )	Hagiwara N....Yamashita K.	2003
3	Mucoepidermoid carcinoma of the esophagus treated by endoscopic mucosal resection. ( 14641323 )	Tamura S....Kaneko T.	2003
4	Primary mucoepidermoid carcinoma of the esophagus misclassified as adenocarcinoma on endoscopic biopsy. ( 11051397 )	Batoon S.B....Co J.	2000

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Genes for Mucoepidermoid Esophageal Carcinoma

Genes related to Mucoepidermoid Esophageal Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	WWOX	WW Domain Containing Oxidoreductase	Protein Coding	13.09	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	TP53	Tumor Protein P53	Protein Coding	13.05	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	CEACAM5	Carcinoembryonic Antigen Related Cell Adhesion Molecule 5	Protein Coding	4.97	DISEASES inferred ¹⁵

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Variations for Mucoepidermoid Esophageal Carcinoma

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Expression for Mucoepidermoid Esophageal Carcinoma

Search GEO for disease gene expression data for Mucoepidermoid Esophageal Carcinoma.

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Pathways for Mucoepidermoid Esophageal Carcinoma

Pathways related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	DNA Damage ⁴	11.09	TP53 WWOX

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GO Terms for Mucoepidermoid Esophageal Carcinoma

Biological processes related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	intrinsic apoptotic signaling pathway by p53 class mediator	GO:0072332	8.62	TP53 WWOX

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