MCID: MCP008
MIFTS: 20

Mucoepidermoid Esophageal Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Mucoepidermoid Esophageal Carcinoma

MalaCards integrated aliases for Mucoepidermoid Esophageal Carcinoma:

Name: Mucoepidermoid Esophageal Carcinoma 12 15
Mucoepidermoid Carcinoma of the Esophagus 12
Esophageal Mucoepidermoid Carcinoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4686
NCIt 50 C5343
UMLS 73 C1333461

Summaries for Mucoepidermoid Esophageal Carcinoma

MalaCards based summary : Mucoepidermoid Esophageal Carcinoma, also known as mucoepidermoid carcinoma of the esophagus, is related to mucoepidermoid carcinoma and esophageal adenosquamous carcinoma. An important gene associated with Mucoepidermoid Esophageal Carcinoma is WWOX (WW Domain Containing Oxidoreductase), and among its related pathways/superpathways is DNA Damage. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Mucoepidermoid Esophageal Carcinoma

Diseases related to Mucoepidermoid Esophageal Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 43)
# Related Disease Score Top Affiliating Genes
1 mucoepidermoid carcinoma 10.2
2 esophageal adenosquamous carcinoma 10.1 CEACAM5 WWOX
3 mucositis 9.9
4 adenocarcinoma 9.9
5 gallbladder squamous cell carcinoma 9.8 CEACAM5 TP53
6 intracranial chondrosarcoma 9.8 CEACAM5 TP53
7 malignant spiradenoma 9.8 CEACAM5 TP53
8 atypical follicular adenoma 9.8 CEACAM5 TP53
9 biliary papillomatosis 9.8 CEACAM5 TP53
10 prostate squamous cell carcinoma 9.8 CEACAM5 TP53
11 ovary adenocarcinoma 9.8 CEACAM5 TP53
12 xanthogranulomatous cholecystitis 9.8 CEACAM5 TP53
13 papillary adenocarcinoma 9.8 CEACAM5 TP53
14 bile duct adenocarcinoma 9.8 CEACAM5 TP53
15 gastrointestinal system benign neoplasm 9.8 CEACAM5 TP53
16 intestinal benign neoplasm 9.8 CEACAM5 TP53
17 ovarian cancer 1 9.8 CEACAM5 TP53
18 malignant ovarian surface epithelial-stromal neoplasm 9.7 CEACAM5 TP53
19 ovary epithelial cancer 9.7 CEACAM5 TP53
20 organ system benign neoplasm 9.7 CEACAM5 TP53
21 integumentary system cancer 9.7 CEACAM5 TP53
22 lymph node cancer 9.7 TP53 WWOX
23 cystadenocarcinoma 9.7 CEACAM5 TP53
24 esophageal basaloid squamous cell carcinoma 9.7 TP53 WWOX
25 cell type benign neoplasm 9.7 CEACAM5 TP53
26 squamous cell papilloma 9.7 TP53 WWOX
27 colorectal adenocarcinoma 9.7 CEACAM5 TP53
28 esophageal disease 9.7 TP53 WWOX
29 female reproductive organ cancer 9.7 CEACAM5 TP53
30 respiratory system cancer 9.6 CEACAM5 TP53
31 rectal neoplasm 9.6 CEACAM5 TP53
32 endocrine gland cancer 9.6 CEACAM5 TP53
33 pancreas adenocarcinoma 9.6 CEACAM5 TP53
34 gallbladder cancer 9.6 CEACAM5 TP53
35 small cell cancer of the lung 9.5 CEACAM5 TP53
36 vaccinia 9.5 CEACAM5 TP53
37 adamantinoma of long bones 9.4 CEACAM5 TP53
38 lung cancer susceptibility 3 9.3 CEACAM5 TP53
39 gastric adenocarcinoma 9.2 CEACAM5 TP53
40 cell type cancer 9.1 CEACAM5 TP53 WWOX
41 gastrointestinal system cancer 9.1 CEACAM5 TP53 WWOX
42 esophageal cancer 9.0 CEACAM5 TP53 WWOX
43 cholangiocarcinoma 9.0 CEACAM5 TP53

Graphical network of the top 20 diseases related to Mucoepidermoid Esophageal Carcinoma:



Diseases related to Mucoepidermoid Esophageal Carcinoma

Symptoms & Phenotypes for Mucoepidermoid Esophageal Carcinoma

GenomeRNAi Phenotypes related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

26 (show all 15)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-102 9.83 WWOX
2 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.83 WWOX
3 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.83 TP53
4 Increased shRNA abundance (Z-score > 2) GR00366-A-120 9.83 TP53
5 Increased shRNA abundance (Z-score > 2) GR00366-A-121 9.83 WWOX
6 Increased shRNA abundance (Z-score > 2) GR00366-A-129 9.83 WWOX
7 Increased shRNA abundance (Z-score > 2) GR00366-A-132 9.83 TP53
8 Increased shRNA abundance (Z-score > 2) GR00366-A-164 9.83 WWOX
9 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.83 TP53 WWOX
10 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.83 TP53 WWOX
11 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.83 TP53
12 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.83 TP53
13 Increased shRNA abundance (Z-score > 2) GR00366-A-39 9.83 TP53
14 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.83 WWOX
15 Decreased viability with paclitaxel GR00293-A 8.96 WWOX TP53

Drugs & Therapeutics for Mucoepidermoid Esophageal Carcinoma

Search Clinical Trials , NIH Clinical Center for Mucoepidermoid Esophageal Carcinoma

Genetic Tests for Mucoepidermoid Esophageal Carcinoma

Anatomical Context for Mucoepidermoid Esophageal Carcinoma

Publications for Mucoepidermoid Esophageal Carcinoma

Articles related to Mucoepidermoid Esophageal Carcinoma:

# Title Authors Year
1
Primary mucoepidermoid carcinoma of the esophagus. ( 21587086 )
2011
2
Biological behavior of mucoepidermoid carcinoma of the esophagus. ( 14578940 )
2003
3
Mucoepidermoid carcinoma of the esophagus treated by endoscopic mucosal resection. ( 14641323 )
2003
4
Primary mucoepidermoid carcinoma of the esophagus misclassified as adenocarcinoma on endoscopic biopsy. ( 11051397 )
2000

Variations for Mucoepidermoid Esophageal Carcinoma

Expression for Mucoepidermoid Esophageal Carcinoma

Search GEO for disease gene expression data for Mucoepidermoid Esophageal Carcinoma.

Pathways for Mucoepidermoid Esophageal Carcinoma

Pathways related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.09 TP53 WWOX

GO Terms for Mucoepidermoid Esophageal Carcinoma

Biological processes related to Mucoepidermoid Esophageal Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 8.62 TP53 WWOX

Sources for Mucoepidermoid Esophageal Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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