Mucormycosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: MCR141 MIFTS: 49	Mucormycosis Categories: Immune diseases, Infectious diseases, Oral diseases, Rare diseases, Respiratory diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

Sources

Aliases & Classifications for Mucormycosis

MalaCards integrated aliases for Mucormycosis:

Name: Mucormycosis ¹² ⁷⁶ ⁵⁹ ³ ¹⁵

Zygomycosis ¹² ⁷⁶ ⁵³ ⁵⁹ ³

Disseminated Mucormycosis ¹²

Characteristics:

Orphanet epidemiological data:

⁵⁹

zygomycosis
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

MalaCards categories:
Global: Rare diseases Infectious diseases
Anatomical: Respiratory diseases Immune diseases Oral diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴ ³³

Certain infectious and parasitic diseases

Mycoses

Zygomycosis

Cutaneous mucormycosis

Disseminated mucormycosis

Gastrointestinal mucormycosis

Mucormycosis, unspecified

Other zygomycoses

Pulmonary mucormycosis

Rhinocerebral mucormycosis

Zygomycosis, unspecified

Orphanet: ⁵⁹

Rare infectious diseases

External Ids:

Disease Ontology ¹² DOID:8485

Orphanet ⁵⁹ ORPHA73263

ICD10 via Orphanet ³⁴ B46.0 B46.1 B46.2 more

MESH via Orphanet ⁴⁵ D009091 D020096

UMLS via Orphanet ⁷⁴ C0026718 C0043541

ICD10 ³³ B46 B46.4 B46.5 more

Sources

Summaries for Mucormycosis

CDC : ³ Mucormycosis (previously called zygomycosis) is a serious but rare fungal infection caused by a group of molds called mucormycetes. These molds live throughout the environment. Mucormycosis mainly affects people with weakened immune systems and can occur in nearly any part of the body. It most commonly affects the sinuses or the lungs after inhaling fungal spores from the air, or the skin after the fungus enters the skin through a cut, scrape, burn, or other type of skin trauma.

MalaCards based summary : Mucormycosis, also known as zygomycosis, is related to aspergillosis and carotid artery thrombosis. An important gene associated with Mucormycosis is IFNG (Interferon Gamma), and among its related pathways/superpathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Amoebiasis. The drugs Posaconazole and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and brain, and related phenotype is renal/urinary system.

Disease Ontology : ¹² An opportunistic mycosis that results in fungal infection located in sinuses, located in brain, or located in lungs of immunocompromised people, has material basis in Mucorales molds.

Wikipedia : ⁷⁶ Mucormycosis is any fungal infection caused by fungi in the order Mucorales. Generally, species in the... more...

Sources

Related Diseases for Mucormycosis

Diseases related to Mucormycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 235)

#	Related Disease	Score	Top Affiliating Genes
1	aspergillosis	30.7	CSF2 IFNG
2	carotid artery thrombosis	29.8	CSF2 IFNG
3	acquired immunodeficiency syndrome	29.7	CSF2 IFNG
4	chronic granulomatous disease	29.6	CSF2 IFNG
5	leukemia	10.4
6	lymphocytic leukemia	10.3
7	diabetes mellitus	10.2
8	thrombosis	10.2
9	leukemia, acute lymphoblastic	10.2
10	leukemia, acute myeloid	10.1
11	invasive aspergillosis	10.1
12	lymphoma	10.1
13	myeloid leukemia	10.1
14	large granular lymphocyte leukemia	10.1	CSF2 IFNG
15	trichosporonosis	10.1	CSF2 IFNG
16	candida glabrata	10.1	CSF2 IFNG
17	human t-cell leukemia virus type 2	10.1	CSF2 IFNG
18	meconium aspiration syndrome	10.1	CSF2 IFNG
19	hypersplenism	10.1	CSF2 IFNG
20	cytomegalovirus retinitis	10.1	CSF2 IFNG
21	cryptococcal meningitis	10.1	CSF2 IFNG
22	smallpox	10.1	CSF2 IFNG
23	langerhans cell histiocytosis	10.1	CSF2 IFNG
24	pulmonary sarcoidosis	10.1	CSF2 IFNG
25	systemic lupus erythematosus	10.1
26	paranasal sinus disease	10.1	IFNG RHNO1
27	opportunistic mycosis	10.1	IFNG RHNO1
28	monocytic leukemia	10.1	CSF2 IFNG
29	ethmoid sinusitis	10.1	CSF2 RHNO1
30	upper respiratory tract disease	10.0	IFNG RHNO1
31	diabetes mellitus, ketosis-prone	10.0
32	acute lymphocytic leukemia	10.0
33	osteomyelitis	10.0
34	lupus erythematosus	10.0
35	respiratory system disease	10.0	CSF2 IFNG
36	liver cirrhosis	10.0
37	sarcoidosis 1	10.0	CSF2 IFNG
38	bacterial infectious disease	10.0	CSF2 IFNG
39	candidiasis	10.0
40	cavernous sinus thrombosis	10.0
41	pneumonia	10.0
42	carotid artery occlusion	10.0
43	leukemia, chronic lymphocytic 2	9.9
44	leukemia, chronic lymphocytic	9.9
45	enterocolitis	9.9
46	acute leukemia	9.9
47	neutropenia	9.9
48	pulmonary tuberculosis	9.9
49	perinatal necrotizing enterocolitis	9.9
50	leukemia, b-cell, chronic	9.9

Graphical network of the top 20 diseases related to Mucormycosis:

Sources

Symptoms & Phenotypes for Mucormycosis

MGI Mouse Phenotypes related to Mucormycosis:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	renal/urinary system	MP:0005367	8.92	CSF2 HSPA5 IFNG TREH

Sources

Drugs & Therapeutics for Mucormycosis

Drugs for Mucormycosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Posaconazole

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2

171228-49-2

147912

Synonyms:

1-((1S,2S)-1-Ethyl-2-hydroxypropyl)-4-{4-[4-(4-{[(5S,3R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazolylmethyl)oxolan-3-yl]methoxy}phenyl)piperazinyl]phenyl}-1,2,4-triazolin-5-one

171228-49-2

177571-33-4

4-(p-(4-(p-(((3R,5R)-5-(2,4-Difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furyl)methoxy)phenyl)-1-piperazinyl)phenyl)-1-((1S,2S)-1-ethyl-2-hydroxypropyl)-delta(sup 2)-1,2,4-triazolin-5-one

4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

4-[4-[4-[4-[[(5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

AC-1350

AC1L3W34

AC1LAHLQ

AKOS005145917

CHEBI:434337

CHEMBL1397

CHEMBL371938

CHEMBL371939

CID10532764

CID11520437

CID11542142

CID147912

CID468595

D02555

DB01263

HSDB 7421

LS-186118

LS-186988

LS-187630

MolPort-006-666-426

Noxafil

Noxafil (TN)

Noxafil, Posaconazole

Posaconazole

Posaconazole (USAN/INN)

Posaconazole [USAN:INN:BAN]

Posaconazole in combination with MGCD290

Posaconazole SP

S1257_Selleck

Sch 56592

SCH56592

SCH-56592

Spriafil

UNII-6TK1G07BHZ

X2N

Miconazole

Approved, Investigational, Vet_approved

Phase 4,Phase 3,Phase 2

22916-47-8

4189

Synonyms:

(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole

1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole

1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole

1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole

1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole

1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

22832-87-7 (NITRATE)

22916-47-8

75319-47-0

AB00053500

AC1L1HM1

Aflorix(nitrate)

AKOS001574474

Albistat(nitrate)

Andergin(nitrate)

BPBio1_000279

BRD-A82396632-001-03-0

BRD-A82396632-008-02-7

Brentan

BRN 0965511

BSPBio_000253

BSPBio_002033

CCRIS 7924

CHEBI:6923

CHEMBL91

CID4189

Conofite(nitrate)

CPD-4501

D00416

Dactarin

Daktarin iv

Daktarin IV

DB01110

DivK1c_000156

EINECS 245-324-5

Epi-Monistat(nitrate)

Esteve brand OF miconazole

Femizol-M

Florid(nitrate)

Gyno-Daktar(nitrate)

HMS1568M15

HMS2090B21

I14-14342

IDI1_000156

imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)

Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)

Janssen cilag brand OF miconazole

Janssen-cilag brand OF miconazole

Johnston and johnston brand OF miconazole nitrate

KBio1_000156

KBio2_001445

KBio2_004013

KBio2_006581

KBio3_001533

KBioGR_000581

KBioSS_001445

Lotrimin AF(nitrate)

LS-78378

MCZ

Micantin (nitrate)

Miconasil nitrate

Miconasil Nitrate

Miconazol

Miconazol [INN-Spanish]

miconazole

Miconazole

Miconazole (JP15/USP/INN)

Miconazole [USAN:BAN:INN:JAN]

Miconazole 3

Miconazole 3 Combination Pack

Miconazole 7 Combination Pack

Miconazole esteve brand

Miconazole janssen-cilag brand

Miconazole nitrate

Miconazole nitrate salt

Miconazole-7

Miconazolo

Miconazolo [DCIT]

Miconazolum

Miconazolum [INN-Latin]

Micozole

Minostate

MJR 1762

MLS002222203

MolPort-002-557-553

Monazole 7

Monista (nitrate)

Monistat

Monistat (TN)

Monistat 1 Combination Pack

Monistat 3 Dual-Pak

Monistat 3 Vaginal Ovules

Monistat 5 Tampon

Monistat 7 Dual-Pak

Monistat 7 Vaginal Suppositories

Monistat Dual- PAK

Monistat IV

Monistat iv (tn)

Monistat iv (TN)

Monistat-Derm

NCI60_001353

NCI60_001380

NINDS_000156

Nitrate, miconasil

Nitrate, miconazole

Novo-Miconazole Vaginal Ovules

NSC 170986

NSC169434

NSC170986

Oprea1_091955

Prestwick_335

Prestwick0_000067

Prestwick1_000067

Prestwick2_000067

Prestwick3_000067

R 18134

R-14,889

SMR001307249

SPBio_000976

SPBio_002174

Spectrum_000965

Spectrum2_001048

Spectrum3_000507

Spectrum4_000061

Spectrum5_001297

STK834405

STOCK1S-93556

UNII-7NNO0D7S5M

Vusion

Zimycan

Cytochrome P-450 Enzyme Inhibitors

Phase 4,Phase 3,Phase 2

Hormones

Phase 4,Phase 3,Phase 2

Anti-Infective Agents

Phase 4,Phase 3,Phase 2

Steroid Synthesis Inhibitors

Phase 4,Phase 3,Phase 2

Antiparasitic Agents

Phase 4,Phase 3,Phase 2

Hormone Antagonists

Phase 4,Phase 3,Phase 2

Antifungal Agents

Phase 4,Phase 3,Phase 2

Antiprotozoal Agents

Phase 4,Phase 3,Phase 2

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 4,Phase 3,Phase 2

Voriconazole

Approved, Investigational

Phase 3

137234-62-9

71616

Synonyms:

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol

(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

(AlphaR,betas)-a-(2,4-difluorophenyl)-5-fluoro-b-methyl-a(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

(alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

(alphaR,betaS)-alpha-(2,4-Difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

(AlphaR,betas)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

(AlphaR,betas)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

(R-(R*,s*))-a-(2,4-difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

(R-(R*,s*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

(R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

(R-(R*,s*))-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

137234-62-9

173967-54-9

AC1L2GHR

AC1Q4O6I

AC-823

AKOS005145705

C07622

C102790

CHEBI:10023

CHEMBL638

CID71616

CPD000466350

D00578

DB00582

DRG-0301

FT-0082604

HMS2051N09

LS-181799

MLS000759464

MLS001424082

MolPort-003-850-863

Pfizer brand of voriconazole

S1442_Selleck

SAM001246664

SMR000466350

TL8000858

UK 109,496

UK 109496

UK-109,496

UK-109496

UNII-JFU09I87TR

VCZ

Vfend

Vfend (TN)

Vfend, Voriconazole

Voriconazol

voriconazole

Voriconazole

Voriconazole (JAN/USAN/INN)

Voriconazole [USAN:INN:BAN]

Voriconazole in combination with MGCD290

Voriconazolum

VRC

ZINC00014864

Pharmaceutical Solutions

Phase 3

Cytochrome P-450 CYP3A Inhibitors

Phase 3

Deferasirox

Approved, Investigational

Phase 2

201530-41-8

5493381

Iron

Approved

Phase 2

7439-89-6

23925

Synonyms:

02583_FLUKA

12310_ALDRICH

12310_RIEDEL

129048-51-7

14067-02-8

161135-39-3

190454-13-8

195161-83-2

199281-22-6

209309_ALDRICH

209309_SIAL

255637_ALDRICH

266213_ALDRICH

266256_ALDRICH

267945_ALDRICH

267953_ALDRICH

26Fe

338141_ALDRICH

356808_ALDRICH

356824_ALDRICH

356832_ALDRICH

39344-71-3

3ZhP

413054_ALDRICH

443783-52-6

44890_ALDRICH

44890_FLUKA

675141-17-0

70884-35-4

73135-38-3

7439-89-6

8011-79-8

8053-60-9

AC1L2N38

Ancor B

Ancor en 80/150

armco Iron

Armco iron

Atomel 28

Atomel 300M200

Atomel 500M

Atomel 95

Atomiron 44MR

Atomiron 5M

Atomiron AFP 25

Atomiron AFP 5

ATW 230

ATW 432

C00023

C3518_SIAL

C3518_SIGMA

Carbonyl iron

CCRIS 1580

CHEBI:18248

CID23925

Copy Powder CS 105-175

D007501

DB01592

Diseases (animal), iron overload

Diseases, iron overload

DSP 1000

DSP 128B

DSP 135

DSP 135C

DSP 138

Ed-In-Sol

EF 1000

EF 250

EFV 200/300

EFV 250

EFV 250/400

EINECS 231-096-4

Eisen

Electrolytic iron

F 60 (metal)

FE (II) ion

Fe(2+)

Fe(II)

Fe1+

Fe-40

fer

Feronate

Ferretts

Ferro-Caps

Ferro-Time

Ferrous ion

ferrous iron

Ferrousal

Ferrovac e

Ferrovac E

Ferrum

Ferrum metallicum

FT 3 (element)

GS 6

Hematite

Hemocyte

HF 2 (element)

hierro

Hierro

HL (iron)

Hoeganaes ATW 230

Hoeganaes EH

HQ (metal)

HS (iron)

HS 4849

HSDB 604

Infed

IRMM524A_FLUKA

IRMM524B_FLUKA

IRON

Iron (Fe)

Iron (Fe1+)

Iron ion (Fe+)

Iron ion(1+)

Iron ion(2+)

Iron monocation

Iron powder

Iron standard for AAS

Iron(1+)

Iron(1+) ion

Iron(III) nitrate solution

Iron, carbonyl

Iron, electrolytic

Iron, elemental

Iron, ion (Fe1+)

Iron, ion (Fe1+) (8CI,9CI)

Iron, reduced

Limonite

LOHA

LS-3196

Magnetite

Malleable iron

Metopirone

Metyrapone

MolPort-003-925-001

NC 100

PZh1M1

PZh-1M3

PZh-2

PZh2M

PZH2m

PZh2M1

PZh2M2

PZh3

PZh3M

PZh4M

PZhO

PZHO

Reduced iron

Remko

Siderol

Suy-b 2

SUY-B 2

Taconite

UNII-E1UOL152H7

Venofer

Vitedyn-Slo

Wrought iron

Yieronia

Amphotericin B

Approved, Investigational

Phase 2

1397-89-3

5280965 14956

Synonyms:

12633-72-6

1397-89-3

30782-62-8

5-18-10-00525 (Beilstein Handbook Reference)

54482-28-9

8055-20-7

AB00513832

Abelcet

Abelecet

ABLC

AC1L1CN2

AC1L24V6

AC1L70KF

AC1L73U6

AC1NQXTD

AC1NTQ32

AC1NUQG4

AC1NY9JC

AC1O7GCZ

AC1O8FQV

AC1O8PFK

AI3-26528

Ambap1397-89-3

Ambisome

AmBisome (TN)

Amfotericina b

Amfotericina B

Amfotericina B [INN-Spanish]

amophotericin B

AMPH-b

AMPH-B

Amphocil

Amphocin

Amphomoronal

Ampho-Moronal

Amphortericin b

Amphortericin B

Amphotec

Amphotec (TN)

Amphotericin

Amphotericin .BETA.

amphotericin b

Amphotericin B

Amphotericin B (JP15/USP/INN)

Amphotericin B [USAN:INN:JAN]

Amphotericin b cholesterol dispersion

Amphotericin B Cholesterol Dispersion

Amphotericin b colloidal dispersion

Amphotericin B Colloidal Dispersion

amphotericin B liposomal

Amphotericin B, Lipid-based

Amphotericin B, Streptomyces sp.

Amphotericin-B

Amphotericine b

Amphotericine B

Amphotéricine B

Amphotericine B [INN-French]

Amphotericinum

Amphotericinum b

Amphotericinum B

Amphotericinum B [INN-Latin]

Amphotherizin

Amphotherizin [German]

Amphozone

BIDD:GT0351

BPBio1_000374

BRN 0078342

BSPBio_000340

C06573

C47H73NO17

C-AmB

CCRIS 5963

CHEBI:2682

CHEMBL1200646

CHEMBL267345

CID10533925

CID10629638

CID10677275

CID14956

CID1972

CID352546

CID354192

CID5280965

CID5386092

CID5458486

CID5771695

CID6604295

CID6708817

CID6713692

CID9919339

D00203

DB00681

DivK1c_007045

EINECS 215-742-2

Fungilin

Fungisome

Fungisone

Fungizone

Fungizone (TN)

Halizon

HMS1569A22

HSDB 3008

HSDB 3008 IAB

I06-0257

KBio1_001989

KBio2_000551

KBio2_003119

KBio2_005687

KBioGR_002298

KBioSS_000551

Liposomal amphotericin b

Liposomal Amphotericin B

LMPK06000002

LNS-AmB

LS-187721

LS-93

MLS002702966

MolPort-006-392-260

Mysteclin-F

NCGC00014913

NCGC00090808-01

NCGC00098014-01

NCGC00179595-01

NCI527017

NCI60_004288

NCIStruc1_001042

NCIStruc2_000920

NKTR-024

NS 718

NSC 527017

NSC527017

NSC-527017

Prestwick_721

Prestwick0_000410

Prestwick1_000410

Prestwick2_000410

Prestwick3_000410

SinuNase

SMP1_000302

SMR001566780

SPBio_000715

SPBio_002279

SpecPlus_000949

Spectrum_000111

Spectrum2_000818

Spectrum4_001779

ST50999656

UNII-7XU7A7DROE

Chelating Agents

Phase 2

Iron Chelating Agents

Phase 2

Anti-Bacterial Agents

Phase 2

Liposomal amphotericin B

Phase 2

Interventional clinical trials:

(show all 15)

#	Name	Status	NCT ID	Phase	Drugs
1	Limited Access Protocol of Posaconazole in Invasive Fungal Infections Study PO2095	Terminated	NCT00177749	Phase 4	Posaconazole
2	Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101)	Completed	NCT02180165	Phase 3	Posaconazole;Voriconazole
3	Clinical Study of AK1820 (Isavuconazonium Sulfate) for the Treatment of Deep Mycosis	Recruiting	NCT03471988	Phase 3	AK1820;Voriconazole
4	Endoscopic Surgical Treatment of Rhino-Sinusal Mucormycosis	Unknown status	NCT02226705	Phase 2
5	The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) Study	Completed	NCT00419770	Phase 2	deferasirox;Placebo;Liposomal amphotericin B
6	Pilot Study of High Dose Liposomal Amphotericin B Efficacy in Initial Zygomycosis Treatment	Completed	NCT00467883	Phase 2	Liposomal Amphotericin B
7	PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893)	Completed	NCT00034671	Phase 2	Posaconazole oral suspension
8	Study of Isavuconazole Prophylaxis in Adults With Acute Myeloid Leukemia/Myelodysplastic Syndrome (AML/MDS) and Neutropenia	Recruiting	NCT03019939	Phase 2	Isavuconazole
9	A Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucormycosis (IM) in Pediatric Participants	Not yet recruiting	NCT03816176	Phase 2	Isavuconazonium sulfate
10	Prospective Evaluation of a New Molecular Tool for Early Diagnosis of Mucormycosis	Completed	NCT02845934	Not Applicable
11	Descriptive Epidemiology on Management of Mucormycosis	Completed	NCT03429023
12	Early Molecular Detection for the Improved Diagnosis of Invasive Pulmonary Aspergillosis and Invasive Pulmonary Zygomycosis	Completed	NCT00923832
13	Invasive Mould Infections in Indian ICUs - Descriptive Epidemiology, Management and Outcome	Completed	NCT02683642
14	Mucormycosis in ICU	Recruiting	NCT03387696
15	Markers of Pulmonary Dysbiosis Associated With Exacerbation in Patients Followed for Cystic Fibrosis	Not yet recruiting	NCT03569904

Search NIH Clinical Center for Mucormycosis

Sources

Genetic Tests for Mucormycosis

Sources

Anatomical Context for Mucormycosis

MalaCards organs/tissues related to Mucormycosis:

⁴¹

Lung, Skin, Brain, Liver, Kidney, Myeloid, Bone

The Foundational Model of Anatomy Ontology organs/tissues related to Mucormycosis:

¹⁹

Brain, Sinuses, Lungs Of Immunocompromised People

Sources

Publications for Mucormycosis

Articles related to Mucormycosis:

(show top 50) (show all 1129)

#	Title	Authors	Year
1	Treatment of cerebral mucormycosis with drug therapy alone: A case report. ( 30425919 )	Elzein F...Albadani A	2019
2	Cutaneous Mucormycosis Following a Bullous Pemphigoid Flare in a Chronic Lymphocytic Leukemia Patient on Ibrutinib. ( 29760835 )	Stein M.K....Zare F.	2018
3	Spotlight on isavuconazole in the treatment of invasive aspergillosis and mucormycosis: design, development, and place in therapy. ( 29750016 )	Jenks J.D....Hoenigl M.	2018
4	How we approach combination antifungal therapy for invasive aspergillosis and mucormycosis in transplant recipients. ( 29975240 )	Haidar G....Singh N.	2018
5	Management of Recurrent Rhinomaxillary Mucormycosis and Nasal Myiasis in an Uncontrolled Diabetic Patient: A Systematic Approach. ( 29744327 )	Manjunath N.M....Pinto P.M.	2018
6	Mucormycosis Osteomyelitis of the Hand. ( 29934077 )		2018
7	Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease. ( 30148059 )	Leo F...Groh? C	2018
8	Tumor shape pulmonary mucormycosis associated with sinonasal aspergillosis in a diabetic patient. ( 29188178 )	Point S...Blanchard E	2018
9	Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis. ( 29560305 )	Persichino JG...Filler SG	2018
10	Primary Cutaneous Mucormycosis in a Beta-Thalassemia Patient. ( 30369766 )	Sepaskhah M...Sari Aslani F	2018
11	Orbitocerebral Mucormycosis in a Patient With Central Nervous System Lymphoma. ( 30320719 )	Beketova TR...Adesina OO	2018
12	Pulmonary mucormycosis in an adolescent female with type 1 diabetes mellitus. ( 30524955 )	Pennell E...Galvis AE	2018
13	Successful Treatment of Concurrent Mucormycosis and Diffuse Alveolar Hemorrhage in a Patient With Newly Diagnosed Systemic Lupus Erythematosus. ( 30207572 )	Seo MR...Baek HJ	2018
14	Mucormycosis Endophthalmitis in a Silicone Oil-Filled Eye of an Immunocompetent Patient. ( 30192700 )	Dogra M...Gupta V	2018
15	An Interesting Case of a 57-Year-Old Male with an Upper Gastrointestinal Bleeding and Obstructive Uropathy with Bilateral Hydronephrosis Diagnosed with Systemic Mucormycosis. ( 30026991 )	Izaguirre-Anariba DE...Lanza J	2018
16	Invasive rhinocerebral mucormycosis in a patient with liver cirrhosis leading to fatal massive stroke. ( 30294535 )	Sabobeh T...Rashid S	2018
17	Cutaneous mucormycosis caused by Saksenaea vasiformis in a patient with systemic lupus erythematosus. ( 30214752 )	Sigera LSM...Fernando AHN	2018
18	Pulmonary Mucormycosis in Chronic Lymphocytic Leukemia and Neutropenia. ( 29670779 )	Mir I...Mohanty E	2018
19	Rhinoorbitocerebral Mucormycosis with Maggots in a Neglected Diabetic Patient. ( 29456961 )	Pathak VK...Singh SK	2018
20	Invasive Cutaneous Facial Mucormycosis in a Trauma Patient. ( 29458027 )	Jundt JS...Demian NM	2018
21	Pulmonary Mucormycosis: Radiologic Features at Presentation and Over Time. ( 29470162 )	Hammer MM...Hatabu H	2018
22	In Situ Validation of the Endothelial Cell Receptor GRP78 in a Case of Rhinocerebral Mucormycosis. ( 29483124 )	Shumilov E...Venkataramani V	2018
23	Mucormycosis in immunocompetent patient resulting in extensive maxillary sequestration. ( 29491619 )	Venkatesh D...Hema KN	2018
24	Challenges in the diagnosis and treatment of mucormycosis. ( 29538730 )	Skiada A...Petrikkos G	2018
25	Mucormycosis in Iran: A six-year retrospective experience. ( 29545123 )	Dolatabadi S...Makimura K	2018
26	Mucormycosis: Early Identification of a Deadly Fungus [Formula: see text]. ( 29560764 )	Brettholz AM...Mccauley SO	2018
27	Invasive cutaneous mucormycosis in a preterm neonate presenting as a vesicobullous lesion. ( 29567895 )	Mishra S...Bharadwaj R	2018
28	Isolated cutaneous mucormycosis in a pediatric renal transplant recipient. ( 29569805 )	Downie ML...Robinson LA	2018
29	Invasive Gastrointestinal Mucormycosis: A Master Masquerader. ( 29570587 )	Gupta S...Mitra S	2018
30	Gastric Mucormycosis in a Liver and Kidney Transplant Recipient: Case Report and Concise Review of Literature. ( 29573830 )	Alfano G...Cappelli G	2018
31	Comparative genome-wide analysis of extracellular small RNAs from the mucormycosis pathogen Rhizopus delemar. ( 29588481 )	Liu M...Wang P	2018
32	Successful Conservative Management of Bilateral Renal Mucormycosis. ( 29601838 )	Marsh BM...Borofsky MS	2018
33	Successful Use of a Double Lumen Endotracheal Tube and Bronchial Blocker for Lung Isolation in Pulmonary Mucormycosis. ( 29631944 )	Wanat-Hawthorne A...Kernstine K	2018
34	Mucormycosis: Battle with the Deadly Enemy over a Five-Year Period in India. ( 29642408 )	Chander J...Guarro J	2018
35	Endobronchial Mucormycosis Successfully Treated with Flexible Bronchoscopic Cryotherapy. ( 29648882 )	Choe YH...Kim SR	2018
36	Cutaneous mucormycosis as a presenting feature of type 1 diabetes in a boy - case report and review of the literature. ( 29672274 )	Jevalikar G...Mithal A	2018
37	Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing. ( 29691339 )	Garcia-Hermoso D...Alanio A	2018
38	Urokinase application for hemothorax in pulmonary mucormycosis. ( 29707367 )	Hodel L...Hillinger S	2018
39	Development of a quantitative PCR detecting Cunninghamella bertholletiae to help in diagnosing this rare and aggressive mucormycosis. ( 29712993 )	Bellanger AP...Millon L	2018
40	Mucormycosis of maxilla following tooth extraction in immunocompetent patients: Reports and review. ( 29721234 )	Nilesh K...Vande AV	2018
41	Total Gastric Necrosis Due to Mucormycosis: A Rare Case of Gastric Perforation. ( 29724988 )	Termos S...Sapkal A	2018
42	Characteristics of pulmonary mucormycosis and predictive risk factors for the outcome. ( 29748841 )	Feng J...Sun X	2018
43	Non-sinonasal isolated facio-orbital mucormycosis - A case report. ( 29773436 )	Swain SK...Banerjee A	2018
44	Ruptured Mycotic Aneurysm of the Distal Circulation in a Patient with Mucormycosis Without Direct Skull Base Extension: Case Report. ( 29800469 )	Rangwala SD...Russin JJ	2018
45	On the Nose: Disseminated Mucormycosis. ( 29806997 )	Danneels P...Dub?e V	2018
46	Thoracoabdominal Resection of Mucormycosis Lesions in a Leukemic Patient. ( 29807006 )	Kalogerakos PD...Chalkiadakis G	2018
47	Voriconazole associated mucormycosis in a patient with relapsed acute lymphoblastic leukemia and hematopoietic stem cell transplant failure: A case report. ( 29807852 )	Sharifpour A...Shokohi T	2018
48	Neonatal Mucormycosis with Gastrointestinal and Cutaneous involvement. ( 29845959 )	Devi RU...Pappathi S	2018
49	Self-resolving superficial primary cutaneous mucormycosis in a 7-week-old infant. ( 29846009 )	Jones MU...Eberly MD	2018
50	Gastrointestinal mucormycosis in apparently immunocompetent hosts-A review. ( 29855116 )	Kaur H...Chakrabarti A	2018

Sources

Genes for Mucormycosis

Genes related to Mucormycosis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	IFNG	Interferon Gamma	Protein Coding	21.98	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	HSPA5	Heat Shock Protein Family A (Hsp70) Member 5	Protein Coding	20.95	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	RHNO1	RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1	Protein Coding	20.42	DISEASES inferred ¹⁵
4	CSF2	Colony Stimulating Factor 2	Protein Coding	19.94	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	TREH	Trehalase	Protein Coding	14.54	DISEASES inferred ¹⁵
6	ARF4	ADP Ribosylation Factor 4	Protein Coding	14.51	DISEASES inferred ¹⁵
7	BFSP1	Beaded Filament Structural Protein 1	Protein Coding	14.42	DISEASES inferred ¹⁵

Sources

Variations for Mucormycosis

Sources

Expression for Mucormycosis

Search GEO for disease gene expression data for Mucormycosis.

Sources

Pathways for Mucormycosis

Pathways related to Mucormycosis according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.54	CSF2 IFNG
2	Amoebiasis ³⁷	11.44	CSF2 IFNG
3	Rheumatoid arthritis ³⁷	11.39	CSF2 IFNG
4	Salmonella infection (KEGG) ³⁷	11.34	CSF2 IFNG
5	Glucocorticoid receptor regulatory network ¹	11.28	CSF2 IFNG
6	Calcineurin-regulated NFAT-dependent transcription in lymphocytes ¹ Show member pathways Calcium signaling in the CD4+ TCR pathway ¹	11.2	CSF2 IFNG
7	Dendritic Cells Developmental Lineage Pathway ⁶⁵	11.13	CSF2 IFNG
8	Microglia Activation During Neuroinflammation: Microglia Polarization ⁶⁵	11.01	CSF2 IFNG
9	Photodynamic therapy-induced NF-kB survival signaling ¹ Show member pathways Immune response MIF-mediated glucocorticoid regulation ²²	10.76	CSF2 IFNG
10	Cytokines and Inflammatory Response ¹	10.09	CSF2 IFNG

Sources

GO Terms for Mucormycosis

Biological processes related to Mucormycosis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of tyrosine phosphorylation of STAT protein	GO:0042531	8.96	CSF2 IFNG
2	positive regulation of interleukin-23 production	GO:0032747	8.62	CSF2 IFNG

Sources

Sources for Mucormycosis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia