MCRCC
MCID: MLT165
MIFTS: 28

Multilocular Cystic Renal Neoplasm of Low Malignant Potential (MCRCC)

Categories: Cancer diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

MalaCards integrated aliases for Multilocular Cystic Renal Neoplasm of Low Malignant Potential:

Name: Multilocular Cystic Renal Neoplasm of Low Malignant Potential 59
Multilocular Clear Cell Renal Cell Adenocarcinoma 59
Multilocular Cystic Renal Cell Adenocarcinoma 59
Multilocular Clear Cell Renal Cell Carcinoma 59
Multilocular Cystic Renal Cell Carcinoma 59
Multilocular Clear Cell Adenocarcinoma 59
Multilocular Clear Cell Carcinoma 59
Cystadenocarcinoma of Kidney 72
Mcrcc 59

Classifications:

Orphanet: 59  
Rare renal diseases


External Ids:

ICD10 via Orphanet 34 C64
Orphanet 59 ORPHA319287
UMLS 72 C0346249

Summaries for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

MalaCards based summary : Multilocular Cystic Renal Neoplasm of Low Malignant Potential, also known as multilocular clear cell renal cell adenocarcinoma, is related to multilocular clear cell renal cell carcinoma and cystic nephroma, and has symptoms including flank pain Affiliated tissues include kidney and neutrophil.

Related Diseases for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Diseases related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 multilocular clear cell renal cell carcinoma 12.9
2 cystic nephroma 10.6
3 renal cell carcinoma, nonpapillary 10.5
4 clear cell renal cell carcinoma 10.4
5 cystic kidney disease 10.3
6 multiloculated renal cyst 10.2
7 kidney cancer 10.2
8 crohn's disease 10.2
9 wilms tumor 1 10.1
10 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.1
11 wilms tumor 5 10.1
12 renal cell carcinoma, papillary, 1 10.1
13 leiomyoma 10.1
14 end stage renal failure 10.1
15 chromophil renal cell carcinoma 10.1
16 chromosome 3p deletion 10.1
17 clear cell papillary renal cell carcinoma 10.1
18 rare tumor 10.1

Graphical network of the top 20 diseases related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential:



Diseases related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Symptoms & Phenotypes for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

UMLS symptoms related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential:


flank pain

Drugs & Therapeutics for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Search Clinical Trials , NIH Clinical Center for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Genetic Tests for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Anatomical Context for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

MalaCards organs/tissues related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential:

41
Kidney, Neutrophil

Publications for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Articles related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential:

(show top 50) (show all 109)
# Title Authors PMID Year
1
[Renal cell carcinoma diagnosis and prognosis within the context of the WHO classification 2016]. 38
31093717 2019
2
SETD2, GIGYF2, FGFR3, BCR, KMT2C, and TSC2 as candidate genes for differentiating multilocular cystic renal neoplasm of low malignant potential from clear cell renal cell carcinoma with cystic change. 38
31098421 2019
3
Contemporary update on imaging of cystic renal masses with histopathological correlation and emphasis on patient management. 38
30314810 2019
4
Sorting the Alphabet Soup of Renal Pathology: A Review. 38
26928791 2018
5
RNA sequencing of Xp11 translocation-associated cancers reveals novel gene fusions and distinctive clinicopathologic correlations. 38
29713041 2018
6
Predominantly cystic clear cell renal cell carcinoma and multilocular cystic renal neoplasm of low malignant potential form a low-grade spectrum. 38
29770853 2018
7
[The incidence of malignant transformation of renal cysts of category 1, 2, and 2F by the BOSNIAK classification into multilocular cystic renal cell carcinoma]. 38
30035429 2018
8
Retrospective analysis of 25 immunohistochemical tissue markers for differentiating multilocular cystic renal neoplasm of low malignant potential and multicystic renal cell carcinoma. 38
29292824 2018
9
Multilocular cystic renal cell carcinoma: A case report and review of the literature. 38
29435299 2018
10
Crohn's disease and multilocular cystic renal neoplasm of low malignant potential: An unusual association. 38
29204358 2018
11
Multilocular cystic renal cell carcinoma: pathological t staging makes no difference to favorable outcomes and should be reclassified. Bhatt JR, Jewett MA, Richard PO, Kawaguchi S, Timilshina N, Evans A, Alibhai S, Finelli A.J Urol. November 2016;196(5):1350-1355. 38
28416104 2017
12
Algorithm for Bosniak 2F Cyst in Kidney Donation. 38
28663537 2017
13
Re: Multilocular Cystic Renal Cell Carcinoma: Pathological T Staging Makes No Difference to Favorable Outcomes and Should be Reclassified: J. R. Bhatt, M. A. Jewett, P. O. Richard, S. Kawaguchi, N. Timilshina, A. Evans, S. Alibhai and A. Finelli J Urol 2016;196:1350-1355. 38
28167073 2017
14
Retrospective evaluation of ultrasound-indeterminate renal multilocular cystic masses by using neutrophil-lymphocyte ratio and computed tomography. 38
27671994 2017
15
[Cystic nephroma. Report of two cases and bibliographic review.] 38
28042792 2016
16
Multilocular Cystic Renal Cell Neoplasm of Low Malignant Potential: A Series of 76 Cases. 38
27108004 2016
17
Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist's Perspective. 38
28050373 2016
18
Multilocular Cystic Renal Cell Carcinoma: Pathological T Staging Makes No Difference to Favorable Outcomes and Should be Reclassified. 38
27341751 2016
19
Multilocular cystic renal cell carcinoma in a 23 year old female. 38
28058005 2016
20
Clear cell renal cell tumors: Not all that is "clear" is cancer. 38
26988177 2016
21
Germline mutations in the VHL gene associated with 3 different renal lesions in a Chinese von Hippel-Lindau disease family. 38
27057652 2016
22
Unusual renal tumour: multilocular cystic renal cell carcinoma. 38
26957035 2016
23
Multilocular Cystic Renal Cell Carcinoma or Cystic Nephroma? 38
28074169 2016
24
Multifocal Primary Neoplasms in Kidney Allografts: Evaluation of Two Cases. 38
28326280 2016
25
[CT differential diagnosis of cystic nephroma and multilocular cystic renal cell carcinoma]. 38
26887516 2015
26
Laparoscopic versus open partial nephrectomy for multilocular cystic renal cell carcinoma: a direct comparison based on single-center experience. 38
25115167 2015
27
[Clinicopathologic features and differential diagnosis of multilocular cystic renal cell carcinoma]. 38
25582248 2014
28
Laparoscopic partial nephrectomy for multilocular cystic renal cell carcinoma: a potential gold standard treatment with excellent perioperative outcomes. 38
24754899 2014
29
Clear cell papillary renal cell carcinoma: Incidence, morphological features, immunohistochemical profile, and biologic behavior: A single institution study. 38
24485757 2014
30
Multilocular cystic renal cell carcinoma: a rare, unique entity and diagnostic challenge. 38
24527976 2014
31
Multilocular cystic renal cell carcinoma: a rare entity with review of literature. 38
24696562 2014
32
Uretheral invagination of multilocular cystic nephroma; a case report of a new pathologic variant. 38
25197409 2014
33
No tumor-free waiting period after treatment of multilocular cystic renal cell carcinoma: a new case and review of the literature. 38
25171490 2014
34
Cystic partially regressed clear cell renal cell carcinoma: a potential mimic of multilocular cystic renal cell carcinoma. 38
24117777 2013
35
Re: Rodolfo Montironi, Antonio Lopez-Beltran, Liang Cheng, Marina Scarpelli. Re: Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. Eur Urol 2013;63:400-1. 38
23473580 2013
36
Reply to Jérôme Verine's letter to the editor Re: Rodolfo Montironi, Antonio Lopez-Beltran, Liang Cheng, Marina Scarpelli. Re: Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. Eur Urol 2013;63:400-1. 38
23473578 2013
37
Tubulocystic carcinoma of the kidney: a histologic, immunohistochemical, and ultrastructural study. 38
23525677 2013
38
Clear cell papillary renal cell carcinoma: differential diagnosis and extended immunohistochemical profile. 38
23238627 2013
39
Multilocular cystic renal cell carcinoma a diagnostic dilemma: A case report in a 30-year-old woman. 38
23798872 2013
40
Multilocular cystic renal cell carcinoma: a rare entity. 38
23559650 2013
41
Words of wisdom: re: multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. 38
23272732 2013
42
Multilocular cystic renal cell carcinoma in lower pole moiety of a duplex kidney. 38
22456872 2012
43
Cystic renal neoplasms and renal neoplasms associated with cystic renal diseases in adults: cross-sectional imaging findings. 38
23192202 2012
44
[Laparoscopic nephron-sparing surgery for treatment of complex cystic renal lesions]. 38
23073588 2012
45
Multilocular cystic renal cell carcinoma: similarities and differences in immunoprofile compared with clear cell renal cell carcinoma. 38
22982885 2012
46
[Clinicopathological study and immunohistochemical expression of CA9 in cystic multilocular renal cell carcinomas]. 38
22920335 2012
47
Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. 38
22763870 2012
48
Can multilocular cystic nephroma be a harbinger of multilocular cystic renal cell carcinoma? 38
23032854 2012
49
Re: Multilocular cystic renal cell carcinoma: comparison of imaging and pathologic findings. 38
22579167 2012
50
Multilocular cystic renal cell carcinoma: comparison of imaging and pathologic findings. 38
22194510 2012

Variations for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Cosmic variations for Multilocular Cystic Renal Neoplasm of Low Malignant Potential:

9 (show top 50) (show all 2155)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM249350 ZNF804A kidney,NS,carcinoma,clear cell renal cell carcinoma c.2363A>C p.Q788P 2:184937759-184937759 3
2 COSM249389 ZNF804A kidney,NS,carcinoma,clear cell renal cell carcinoma c.121G>C p.E41Q 2:184866378-184866378 3
3 COSM249348 ZNF800 kidney,NS,carcinoma,clear cell renal cell carcinoma c.719A>G p.N240S 7:127374617-127374617 3
4 COSM249454 ZNF521 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3298A>G p.S1100G 18:25224620-25224620 3
5 COSM30510 ZNF423 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3559G>A p.V1187I 16:49626188-49626188 3
6 COSM6970086 ZFHX3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.7052G>A p.C2351Y 16:72795630-72795630 3
7 COSM3276983 ZFHX3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.745G>A p.G249S 16:72959401-72959401 3
8 COSM6961023 YES1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1069T>A p.L357I 18:739803-739803 3
9 COSM6935891 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.374C>G p.A125G 11:102114196-102114196 3
10 COSM6946890 XIAP kidney,NS,carcinoma,clear cell renal cell carcinoma c.1001A>T p.K334M 23:123891261-123891261 3
11 COSM6941466 XIAP kidney,NS,carcinoma,renal cell carcinoma unclassified c.563G>C p.G188A 23:123886225-123886225 3
12 COSM249421 WWP2 kidney,NS,carcinoma,clear cell renal cell carcinoma c.2056G>C p.E686Q 16:69936391-69936391 3
13 COSM1272065 WT1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.332C>A p.P111H 11:32434810-32434810 3
14 COSM6201648 WT1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1228+1G>C p.? 11:32391971-32391971 3
15 COSM20759 WNK3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3809C>A p.T1270N 23:54238942-54238942 3
16 COSM249519 VWA8 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3300A>T p.E1100D 13:41701456-41701456 3
17 COSM249385 VWA8 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1286A>G p.Q429R 13:41865963-41865963 3
18 COSM6930635 VTCN1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.98-1G>T p.? 1:117156922-117156922 3
19 COSM26611 VPS13B kidney,NS,carcinoma,clear cell renal cell carcinoma c.2580C>T p.Y860Y 8:99274262-99274262 3
20 COSM14311 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.499C>T p.R167W 3:10149822-10149822 3
21 COSM14312 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.353T>C p.L118P 3:10146526-10146526 3
22 COSM14375 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.343C>T p.H115Y 3:10146516-10146516 3
23 COSM17715 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.221T>A p.V74D 3:10142068-10142068 3
24 COSM17855 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.233A>G p.N78S 3:10142080-10142080 3
25 COSM18024 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.598C>T p.R200W 3:10149921-10149921 3
26 COSM18074 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.193T>C p.S65P 3:10142040-10142040 3
27 COSM18152 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.463G>A p.V155M 3:10146636-10146636 3
28 COSM30224 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.326T>G p.I109S 3:10142173-10142173 3
29 COSM14318 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.231C>A p.C77* 3:10142078-10142078 3
30 COSM14373 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.400G>T p.E134* 3:10146573-10146573 3
31 COSM14389 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.452T>G p.I151S 3:10146625-10146625 3
32 COSM97151 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.477A>T p.K159N 3:10149800-10149800 3
33 COSM1417312 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.424G>A p.V142I 3:10146597-10146597 3
34 COSM14400 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.194C>T p.S65L 3:10142041-10142041 3
35 COSM17657 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.472C>G p.L158V 3:10149795-10149795 3
36 COSM17909 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.482G>C p.R161P 3:10149805-10149805 3
37 COSM18350 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.256C>T p.P86S 3:10142103-10142103 3
38 COSM14290 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.240T>A p.S80R 3:10142087-10142087 3
39 COSM14407 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.388G>C p.V130L 3:10146561-10146561 3
40 COSM18005 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.340+1G>A p.? 3:10142188-10142188 3
41 COSM18353 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.331A>G p.S111G 3:10142178-10142178 3
42 COSM18355 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.453C>G p.I151M 3:10146626-10146626 3
43 COSM14346 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.266T>C p.L89P 3:10142113-10142113 3
44 COSM14380 VHL kidney,NS,carcinoma,renal cell carcinoma unclassified c.548C>A p.S183* 3:10149871-10149871 3
45 COSM18015 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.194C>A p.S65* 3:10142041-10142041 3
46 COSM97142 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.264G>T p.W88C 3:10142111-10142111 3
47 COSM97146 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.357C>A p.F119L 3:10146530-10146530 3
48 COSM14363 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.458T>C p.L153P 3:10146631-10146631 3
49 COSM17731 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.288G>T p.Q96H 3:10142135-10142135 3
50 COSM17983 VHL kidney,NS,carcinoma,clear cell renal cell carcinoma c.500G>A p.R167Q 3:10149823-10149823 3

Expression for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Search GEO for disease gene expression data for Multilocular Cystic Renal Neoplasm of Low Malignant Potential.

Pathways for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

GO Terms for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Sources for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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