MCRCC
MCID: MLT165
MIFTS: 28

Multilocular Cystic Renal Neoplasm of Low Malignant Potential (MCRCC)

Categories: Cancer diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

MalaCards integrated aliases for Multilocular Cystic Renal Neoplasm of Low Malignant Potential:

Name: Multilocular Cystic Renal Neoplasm of Low Malignant Potential 58
Multilocular Clear Cell Renal Cell Adenocarcinoma 58
Multilocular Cystic Renal Cell Adenocarcinoma 58
Multilocular Clear Cell Renal Cell Carcinoma 58
Multilocular Cystic Renal Cell Carcinoma 58
Multilocular Clear Cell Adenocarcinoma 58
Multilocular Clear Cell Carcinoma 58
Cystadenocarcinoma of Kidney 70
Mcrcc 58

Classifications:

Orphanet: 58  
Rare renal diseases


External Ids:

ICD10 via Orphanet 33 C64
Orphanet 58 ORPHA319287
UMLS 70 C0346249

Summaries for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

MalaCards based summary : Multilocular Cystic Renal Neoplasm of Low Malignant Potential, also known as multilocular clear cell renal cell adenocarcinoma, is related to multilocular clear cell renal cell carcinoma and nephroma, and has symptoms including flank pain Affiliated tissues include kidney and neutrophil.

Related Diseases for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Diseases related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 multilocular clear cell renal cell carcinoma 11.7
2 nephroma 10.6
3 renal cell carcinoma, nonpapillary 10.6
4 clear cell renal cell carcinoma 10.5
5 cystic kidney disease 10.4
6 kidney cancer 10.3
7 crohn's disease 10.3
8 multiloculated renal cyst 10.3
9 wilms tumor 1 10.1
10 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.1
11 renal cell carcinoma, papillary, 1 10.1
12 leiomyoma 10.1
13 end stage renal disease 10.1
14 chromophil renal cell carcinoma 10.1
15 clear cell papillary renal cell carcinoma 10.1
16 rare tumor 10.1

Graphical network of the top 20 diseases related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential:



Diseases related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Symptoms & Phenotypes for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

UMLS symptoms related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential:


flank pain

Drugs & Therapeutics for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Search Clinical Trials , NIH Clinical Center for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Genetic Tests for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Anatomical Context for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

MalaCards organs/tissues related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential:

40
Kidney, Neutrophil

Publications for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Articles related to Multilocular Cystic Renal Neoplasm of Low Malignant Potential:

(show top 50) (show all 111)
# Title Authors PMID Year
1
Xp11 translocation renal cell carcinoma with morphological features mimicking multilocular cystic renal neoplasm of low malignant potential: a series of six cases with molecular analysis. 61
32699116 2021
2
Contrast-enhanced Ultrasound (CEUS) vs contrast-enhanced computed tomography for multilocular cystic renal neoplasm of low malignant potential: A retrospective analysis for diagnostic performance study. 61
33181678 2020
3
[Renal cell carcinoma diagnosis and prognosis within the context of the WHO classification 2016]. 61
31093717 2019
4
SETD2, GIGYF2, FGFR3, BCR, KMT2C, and TSC2 as candidate genes for differentiating multilocular cystic renal neoplasm of low malignant potential from clear cell renal cell carcinoma with cystic change. 61
31098421 2019
5
Contemporary update on imaging of cystic renal masses with histopathological correlation and emphasis on patient management. 61
30314810 2019
6
Sorting the Alphabet Soup of Renal Pathology: A Review. 61
26928791 2018
7
RNA sequencing of Xp11 translocation-associated cancers reveals novel gene fusions and distinctive clinicopathologic correlations. 61
29713041 2018
8
Predominantly cystic clear cell renal cell carcinoma and multilocular cystic renal neoplasm of low malignant potential form a low-grade spectrum. 61
29770853 2018
9
[The incidence of malignant transformation of renal cysts of category 1, 2, and 2F by the BOSNIAK classification into multilocular cystic renal cell carcinoma]. 61
30035429 2018
10
Retrospective analysis of 25 immunohistochemical tissue markers for differentiating multilocular cystic renal neoplasm of low malignant potential and multicystic renal cell carcinoma. 61
29292824 2018
11
Multilocular cystic renal cell carcinoma: A case report and review of the literature. 61
29435299 2018
12
Crohn's disease and multilocular cystic renal neoplasm of low malignant potential: An unusual association. 61
29204358 2018
13
Algorithm for Bosniak 2F Cyst in Kidney Donation. 61
28663537 2017
14
Multilocular cystic renal cell carcinoma: pathological t staging makes no difference to favorable outcomes and should be reclassified. Bhatt JR, Jewett MA, Richard PO, Kawaguchi S, Timilshina N, Evans A, Alibhai S, Finelli A.J Urol. November 2016;196(5):1350-1355. 61
28416104 2017
15
Re: Multilocular Cystic Renal Cell Carcinoma: Pathological T Staging Makes No Difference to Favorable Outcomes and Should be Reclassified: J. R. Bhatt, M. A. Jewett, P. O. Richard, S. Kawaguchi, N. Timilshina, A. Evans, S. Alibhai and A. Finelli J Urol 2016;196:1350-1355. 61
28167073 2017
16
Retrospective evaluation of ultrasound-indeterminate renal multilocular cystic masses by using neutrophil-lymphocyte ratio and computed tomography. 61
27671994 2017
17
Multilocular Cystic Renal Cell Neoplasm of Low Malignant Potential: A Series of 76 Cases. 61
27108004 2016
18
[Cystic nephroma. Report of two cases and bibliographic review.] 61
28042792 2016
19
Histopathologic Findings in Autopsies with Emphasis on Interesting and Incidental Findings-A Pathologist's Perspective. 61
28050373 2016
20
Multilocular Cystic Renal Cell Carcinoma: Pathological T Staging Makes No Difference to Favorable Outcomes and Should be Reclassified. 61
27341751 2016
21
Multilocular cystic renal cell carcinoma in a 23 year old female. 61
28058005 2016
22
Clear cell renal cell tumors: Not all that is "clear" is cancer. 61
26988177 2016
23
Germline mutations in the VHL gene associated with 3 different renal lesions in a Chinese von Hippel-Lindau disease family. 61
27057652 2016
24
Unusual renal tumour: multilocular cystic renal cell carcinoma. 61
26957035 2016
25
Multilocular Cystic Renal Cell Carcinoma or Cystic Nephroma? 61
28074169 2016
26
Multifocal Primary Neoplasms in Kidney Allografts: Evaluation of Two Cases. 61
28326280 2016
27
[CT differential diagnosis of cystic nephroma and multilocular cystic renal cell carcinoma]. 61
26887516 2015
28
Laparoscopic versus open partial nephrectomy for multilocular cystic renal cell carcinoma: a direct comparison based on single-center experience. 61
25115167 2015
29
[Clinicopathologic features and differential diagnosis of multilocular cystic renal cell carcinoma]. 61
25582248 2014
30
Laparoscopic partial nephrectomy for multilocular cystic renal cell carcinoma: a potential gold standard treatment with excellent perioperative outcomes. 61
24754899 2014
31
Clear cell papillary renal cell carcinoma: Incidence, morphological features, immunohistochemical profile, and biologic behavior: A single institution study. 61
24485757 2014
32
Multilocular cystic renal cell carcinoma: a rare, unique entity and diagnostic challenge. 61
24527976 2014
33
No tumor-free waiting period after treatment of multilocular cystic renal cell carcinoma: a new case and review of the literature. 61
25171490 2014
34
Multilocular cystic renal cell carcinoma: a rare entity with review of literature. 61
24696562 2014
35
Uretheral invagination of multilocular cystic nephroma; a case report of a new pathologic variant. 61
25197409 2014
36
Cystic partially regressed clear cell renal cell carcinoma: a potential mimic of multilocular cystic renal cell carcinoma. 61
24117777 2013
37
Reply to Jérôme Verine's letter to the editor Re: Rodolfo Montironi, Antonio Lopez-Beltran, Liang Cheng, Marina Scarpelli. Re: Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. Eur Urol 2013;63:400-1. 61
23473578 2013
38
Re: Rodolfo Montironi, Antonio Lopez-Beltran, Liang Cheng, Marina Scarpelli. Re: Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. Eur Urol 2013;63:400-1. 61
23473580 2013
39
Clear cell papillary renal cell carcinoma: differential diagnosis and extended immunohistochemical profile. 61
23238627 2013
40
Tubulocystic carcinoma of the kidney: a histologic, immunohistochemical, and ultrastructural study. 61
23525677 2013
41
Multilocular cystic renal cell carcinoma a diagnostic dilemma: A case report in a 30-year-old woman. 61
23798872 2013
42
Multilocular cystic renal cell carcinoma: a rare entity. 61
23559650 2013
43
Words of wisdom: re: multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. 61
23272732 2013
44
Multilocular cystic renal cell carcinoma in lower pole moiety of a duplex kidney. 61
22456872 2012
45
Cystic renal neoplasms and renal neoplasms associated with cystic renal diseases in adults: cross-sectional imaging findings. 61
23192202 2012
46
[Laparoscopic nephron-sparing surgery for treatment of complex cystic renal lesions]. 61
23073588 2012
47
Multilocular cystic renal cell carcinoma: similarities and differences in immunoprofile compared with clear cell renal cell carcinoma. 61
22982885 2012
48
[Clinicopathological study and immunohistochemical expression of CA9 in cystic multilocular renal cell carcinomas]. 61
22920335 2012
49
Multilocular cystic renal cell carcinoma with focus on clinical and pathobiological aspects. 61
22763870 2012
50
Can multilocular cystic nephroma be a harbinger of multilocular cystic renal cell carcinoma? 61
23032854 2012

Variations for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Cosmic variations for Multilocular Cystic Renal Neoplasm of Low Malignant Potential:

9 (show top 50) (show all 6488)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM143616890 ZNF804A kidney,NS,carcinoma,clear cell renal cell carcinoma c.2108A>C p.Q703P 2:184937759-184937759 3
2 COSM88579140 ZNF804A kidney,NS,carcinoma,clear cell renal cell carcinoma c.2363A>C p.Q788P 2:184937759-184937759 3
3 COSM88566796 ZNF804A kidney,NS,carcinoma,clear cell renal cell carcinoma c.121G>C p.E41Q 2:184866378-184866378 3
4 COSM143612455 ZNF804A kidney,NS,carcinoma,clear cell renal cell carcinoma c.-135G>C p.? 2:184866378-184866378 3
5 COSM100952565 ZNF800 kidney,NS,carcinoma,clear cell renal cell carcinoma c.719A>G p.N240S 7:127374617-127374617 3
6 COSM100946000 ZNF800 kidney,NS,carcinoma,clear cell renal cell carcinoma c.719A>G p.N240S 7:127374617-127374617 3
7 COSM85796182 ZNF800 kidney,NS,carcinoma,clear cell renal cell carcinoma c.719A>G p.N240S 7:127374617-127374617 3
8 COSM144685741 ZNF800 kidney,NS,carcinoma,clear cell renal cell carcinoma c.719A>G p.N240S 7:127374617-127374617 3
9 COSM131496685 ZNF521 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3298A>G p.S1100G 18:25224620-25224620 3
10 COSM94790253 ZNF521 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3298A>G p.S1100G 18:25224620-25224620 3
11 COSM140713700 ZNF521 kidney,NS,carcinoma,clear cell renal cell carcinoma c.2638A>G p.S880G 18:25224620-25224620 3
12 COSM84285389 ZNF423 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3559G>A p.V1187I 16:49626188-49626188 3
13 COSM132161238 ZNF423 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3208G>A p.V1070I 16:49626188-49626188 3
14 COSM136721462 ZNF423 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3379G>A p.V1127I 16:49626188-49626188 3
15 COSM136000826 ZNF423 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3379G>A p.V1127I 16:49626188-49626188 3
16 COSM137730910 ZNF423 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3208G>A p.V1070I 16:49626188-49626188 3
17 COSM137390699 ZNF423 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3559G>A p.V1187I 16:49626188-49626188 3
18 COSM137183617 ZNF423 kidney,NS,carcinoma,clear cell renal cell carcinoma c.3379G>A p.V1127I 16:49626188-49626188 3
19 COSM149268221 ZFHX3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.745G>A p.G249S 16:72959401-72959401 3
20 COSM102022298 ZFHX3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.4310G>A p.C1437Y 16:72795630-72795630 3
21 COSM102022947 ZFHX3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.-23-8436G>A p.? 16:72959401-72959401 3
22 COSM87274133 ZFHX3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.745G>A p.G249S 16:72959401-72959401 3
23 COSM87273419 ZFHX3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.7052G>A p.C2351Y 16:72795630-72795630 3
24 COSM149266502 ZFHX3 kidney,NS,carcinoma,clear cell renal cell carcinoma c.7052G>A p.C2351Y 16:72795630-72795630 3
25 COSM152022098 YES1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1069T>A p.L357I 18:739803-739803 3
26 COSM89895108 YES1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1069T>A p.L357I 18:739803-739803 3
27 COSM136836927 YES1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1084T>A p.L362I 18:739803-739803 3
28 COSM133267864 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.374C>G p.A125G 11:102114196-102114196 3
29 COSM143036610 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.374C>G p.A125G 11:102114196-102114196 3
30 COSM145023517 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.374C>G p.A125G 11:102114196-102114196 3
31 COSM127993611 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.374C>G p.A125G 11:102114196-102114196 3
32 COSM90943050 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.374C>G p.A125G 11:102114196-102114196 3
33 COSM126968507 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.-161C>G p.? 11:102114196-102114196 3
34 COSM85232102 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.374C>G p.A125G 11:102114196-102114196 3
35 COSM128447153 YAP1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.374C>G p.A125G 11:102114196-102114196 3
36 COSM94289984 XIAP kidney,NS,carcinoma,clear cell renal cell carcinoma c.1001A>T p.K334M 23:123891261-123891261 3
37 COSM108083403 XIAP kidney,NS,carcinoma,clear cell renal cell carcinoma c.1001A>T p.K334M 23:123891261-123891261 3
38 COSM92180300 XIAP kidney,NS,carcinoma,clear cell renal cell carcinoma c.1001A>T p.K334M 23:123891261-123891261 3
39 COSM108082894 XIAP kidney,NS,carcinoma,renal cell carcinoma unclassified c.563G>C p.G188A 23:123886225-123886225 3
40 COSM92179769 XIAP kidney,NS,carcinoma,renal cell carcinoma unclassified c.563G>C p.G188A 23:123886225-123886225 3
41 COSM94289415 XIAP kidney,NS,carcinoma,renal cell carcinoma unclassified c.563G>C p.G188A 23:123886225-123886225 3
42 COSM137057201 WWP2 kidney,NS,carcinoma,clear cell renal cell carcinoma c.739G>C p.E247Q 16:69936391-69936391 3
43 COSM96278984 WWP2 kidney,NS,carcinoma,clear cell renal cell carcinoma c.2056G>C p.E686Q 16:69936391-69936391 3
44 COSM92965606 WWP2 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1708G>C p.E570Q 16:69936391-69936391 3
45 COSM149735880 WT1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.536C>A p.P179H 11:32434810-32434810 3
46 COSM91370315 WT1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1432+1G>C p.? 11:32391971-32391971 3
47 COSM113481676 WT1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.536C>A p.P179H 11:32434810-32434810 3
48 COSM111527817 WT1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1372+10G>C p.? 11:32391971-32391971 3
49 COSM130509133 WT1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.745+1G>C p.? 11:32391971-32391971 3
50 COSM148578314 WT1 kidney,NS,carcinoma,clear cell renal cell carcinoma c.1423+10G>C p.? 11:32391971-32391971 3

Expression for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Search GEO for disease gene expression data for Multilocular Cystic Renal Neoplasm of Low Malignant Potential.

Pathways for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

GO Terms for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

Sources for Multilocular Cystic Renal Neoplasm of Low Malignant Potential

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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