MS4
MCID: MLT095
MIFTS: 17

Multiple Sclerosis 4 (MS4)

Categories: Genetic diseases, Immune diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Multiple Sclerosis 4

MalaCards integrated aliases for Multiple Sclerosis 4:

Name: Multiple Sclerosis 4 57
Multiple Sclerosis, Susceptibility to, 4 57 13
Ms4 57

Classifications:



External Ids:

OMIM® 57 612596
OMIM Phenotypic Series 57 PS126200

Summaries for Multiple Sclerosis 4

MalaCards based summary : Multiple Sclerosis 4, also known as multiple sclerosis, susceptibility to, 4, is related to triiodothyronine receptor auxiliary protein and multiple sclerosis. An important gene associated with Multiple Sclerosis 4 is MS4 (Multiple Sclerosis, Susceptiblity To, 4). Affiliated tissues include kidney and b cells.

More information from OMIM: 612596 PS126200

Related Diseases for Multiple Sclerosis 4

Diseases in the Multiple Sclerosis family:

Multiple Sclerosis 2 Multiple Sclerosis 3
Multiple Sclerosis 4 Multiple Sclerosis 5
Secondary Progressive Multiple Sclerosis Primary Progressive Multiple Sclerosis

Diseases related to Multiple Sclerosis 4 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 triiodothyronine receptor auxiliary protein 10.0
2 multiple sclerosis 9.8
3 urinary tract infection 9.8
4 acute cystitis 9.8
5 acute retrobulbar neuritis 9.8
6 neuritis 9.8
7 relapsing-remitting multiple sclerosis 9.8
8 lymphopenia 9.8

Graphical network of the top 20 diseases related to Multiple Sclerosis 4:



Diseases related to Multiple Sclerosis 4

Symptoms & Phenotypes for Multiple Sclerosis 4

Clinical features from OMIM®:

612596 (Updated 05-Apr-2021)

Drugs & Therapeutics for Multiple Sclerosis 4

Search Clinical Trials , NIH Clinical Center for Multiple Sclerosis 4

Genetic Tests for Multiple Sclerosis 4

Anatomical Context for Multiple Sclerosis 4

MalaCards organs/tissues related to Multiple Sclerosis 4:

40
Kidney, B Cells

Publications for Multiple Sclerosis 4

Articles related to Multiple Sclerosis 4:

(show all 32)
# Title Authors PMID Year
1
No influence of KIF1B on neurodegenerative markers in multiple sclerosis. 57
21606458 2011
2
Lack of support for association between the KIF1B rs10492972[C] variant and multiple sclerosis. 57
20502484 2010
3
Hexose-6-phosphate dehydrogenase: a new risk gene for multiple sclerosis. 57
19935835 2010
4
Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis. 57
18997785 2008
5
Preventive neurology concepts for training the next-generation and closing gaps in real-world Multiple Sclerosis Care. 61
33296855 2021
6
Automated Radiochemical Synthesis of [18F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases. 61
28605366 2017
7
A gradient in cortical pathology in multiple sclerosis by in vivo quantitative 7 T imaging. 61
25681411 2015
8
Oligoclonal free light chains in cerebrospinal fluid as markers of intrathecal inflammation. Comparison with oligoclonal IgG. 61
25485529 2015
9
Glucose uptake heterogeneity of the leg muscles is similar between patients with multiple sclerosis and healthy controls during walking. 61
25541392 2015
10
Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India. 61
25288834 2014
11
Central vestibular dysfunction in an otorhinolaryngological vestibular unit: incidence and diagnostic strategy. 61
25992098 2014
12
Effects of dalfampridine and its metabolites on cloned human potassium channels Kv 1.1, Kv 1.2, and Kv 1.4 expressed in human embryonic kidney cells. 61
27536438 2013
13
Enhancing neural transmission in multiple sclerosis (4-aminopyridine therapy). 61
23184313 2013
14
Pathogenesis of pediatric multiple sclerosis. 61
22952316 2012
15
B cells as effectors and regulators of autoimmunity. 61
22432804 2012
16
Molecular and biotechnological advances in milk proteins in relation to human health. 61
19689355 2009
17
Improving the evaluation of therapeutic interventions in multiple sclerosis: the role of new psychometric methods. 61
19216837 2009
18
Intraoperative neurophysiological assessment of disabling symptoms in DBS surgery. 61
18083503 2007
19
Multiple sclerosis: interferon beta for some serious forms. 61
18092425 2007
20
Sacral nerve neuromodulation in patients with underlying neurologic disease. 61
17618775 2007
21
Medical marijuana and the developing role of the pharmacist. 61
17494903 2007
22
The long-term safety and tolerability of high-dose interferon beta-1a in relapsing-remitting multiple sclerosis: 4-year data from the PRISMS study. 61
16053475 2005
23
Comprehensive driving assessment: neuropsychological testing and on-road evaluation of brain injured patients. 61
10870430 2000
24
Advantages and risks of ileovesicostomy for the management of neuropathic bladder. 61
10510920 1999
25
Acute encephalopathy: diagnosis and outcome in patients at a regional neurological unit. 61
8208905 1994
26
[Pseudoradicular syndrome in multiple sclerosis. 4 cases diagnosed by magnetic resonance imaging]. 61
1303559 1992
27
In vivo activated T lymphocytes in the peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. 61
2985995 1985
28
Components in multiple sclerosis cerebrospinal fluid that are detected by radioimmunoassay for myelin basic protein. 61
77020 1978
29
[Immunosuppressive treatment of multiple sclerosis. 4. Results of treatment with azathioprine and antilymphocyte globulin (author's transl)]. 61
408666 1977
30
[Multiple sclerosis. 4. Changes of immunoglobulins in the cerebrospinal fluid]. 61
4195036 1970
31
[Studies on the seasonal occurrence on multiple sclerosis. 4. The seasonal occurrence of retrobulbar neuritis in 4 Swiss provinces]. 61
5801177 1969
32
Studies on natural history of multiple sclerosis. 4. Clinical features of the onset bout. 61
5687884 1968

Variations for Multiple Sclerosis 4

Expression for Multiple Sclerosis 4

Search GEO for disease gene expression data for Multiple Sclerosis 4.

Pathways for Multiple Sclerosis 4

GO Terms for Multiple Sclerosis 4

Sources for Multiple Sclerosis 4

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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