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MS5
MCID: MLT124
MIFTS: 14
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Multiple Sclerosis 5 (MS5)
Categories:
Genetic diseases, Immune diseases, Neuronal diseases, Rare diseases
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MalaCards integrated aliases for Multiple Sclerosis 5:
Classifications:
MalaCards categories:
Global: Genetic diseases Rare diseases Anatomical: Neuronal diseases Immune diseases |
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UniProtKB/Swiss-Prot
:
75
Multiple sclerosis 5: A multifactorial, inflammatory, demyelinating disease of the central nervous system. Sclerotic lesions are characterized by perivascular infiltration of monocytes and lymphocytes and appear as indurated areas in pathologic specimens (sclerosis in plaques). The pathological mechanism is regarded as an autoimmune attack of the myelin sheath, mediated by both cellular and humoral immunity. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia and bladder dysfunction. Genetic and environmental factors influence susceptibility to the disease.
MalaCards based summary : Multiple Sclerosis 5, is also known as multiple sclerosis, susceptibility to, 5. An important gene associated with Multiple Sclerosis 5 is TNFRSF1A (TNF Receptor Superfamily Member 1A). Affiliated tissues include monocytes.
Description from OMIM:
614810
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Diseases in the Multiple Sclerosis family:
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MalaCards organs/tissues related to Multiple Sclerosis 5:41
Monocytes
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Articles related to Multiple Sclerosis 5:
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Genes related to Multiple Sclerosis 5 (1 elite genes): - Elite gene
- Cancer Census gene in COSMIC
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ClinVar genetic disease variations for Multiple Sclerosis 5:6
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Search
GEO
for disease gene expression data for Multiple Sclerosis 5.
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