MCID: MNG003
MIFTS: 25

Mungan Syndrome

Categories: Rare diseases, Gastrointestinal diseases, Neuronal diseases, Genetic diseases

Aliases & Classifications for Mungan Syndrome

MalaCards integrated aliases for Mungan Syndrome:

Name: Mungan Syndrome 57 53 13 73
Mgs 57 53
Visceral Neuromyopathy, Familial, with Pseudoobstruction, Megaduodenum, Barrett Esophagus, and Cardiac Abnormalities 57
Visceral Neuromyopathy Familial with Pseudoobstruction Megaduodenum Barrett Esophagus and Cardiac Abnormalities 53
Pseudoobstruction, Chronic Idiopathic Intestinal, with Barrett Esophagus and Cardiac Abnormalities 57
Pseudoobstruction Chronic Idiopathic Intestinal with Barrett Esophagus and Cardiac Abnormalities 53

Characteristics:

OMIM:

57
Inheritance:
autosomal recessive


HPO:

32
mungan syndrome:
Inheritance autosomal recessive inheritance


Classifications:



Summaries for Mungan Syndrome

MalaCards based summary : Mungan Syndrome, also known as mgs, is related to myasthenia gravis and primary hypomagnesemia. An important gene associated with Mungan Syndrome is MGS (Mungan Syndrome). Related phenotypes are vesicoureteral reflux and renal hypoplasia

Wikipedia : 76 Mungan syndrome is first described in 2003 by Mungan Z. et al. as an autosomal recessively inherited... more...

Description from OMIM: 611376

Related Diseases for Mungan Syndrome

Diseases related to Mungan Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 283)
# Related Disease Score Top Affiliating Genes
1 myasthenia gravis 11.9
2 primary hypomagnesemia 11.3
3 myasthenia gravis congenital 11.3
4 familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis 11.1
5 morning glory syndrome 11.1
6 visceral myopathy 11.0
7 hypomagnesemia 3, renal 10.9
8 fetal methylmercury syndrome 10.9
9 maturity-onset diabetes of the young, type 2 10.8
10 anencephaly 10.8
11 hyperphenylalaninemia, bh4-deficient, b 10.8
12 mucopolysaccharidosis type vi 10.8
13 hyperphenylalaninemia, bh4-deficient, a 10.8
14 kearns-sayre syndrome 10.8
15 hypercholesterolemia, autosomal recessive 10.8
16 glut1 deficiency syndrome 1 10.8
17 crigler-najjar syndrome, type ii 10.8
18 aromatase deficiency 10.8
19 adenine phosphoribosyltransferase deficiency 10.8
20 mild phenylketonuria 10.8
21 paroxysmal hemicrania 10.8
22 prostatitis 10.1
23 astrocytoma 10.1
24 depression 10.1
25 major depressive disorder 10.1
26 aging 10.0
27 rosacea 10.0
28 glioblastoma 10.0
29 glioma 10.0
30 breast cancer 10.0
31 prostate cancer 10.0
32 allergic rhinitis 10.0
33 leukemia 10.0
34 candidiasis 10.0
35 rhinitis 10.0
36 osteoporosis 10.0
37 rheumatoid arthritis 10.0
38 arthritis 10.0
39 pyelonephritis 10.0
40 tinea pedis 10.0
41 alopecia 9.9
42 androgenic alopecia 9.9
43 macular retinal edema 9.9
44 acute pyelonephritis 9.9
45 myeloid leukemia 9.9
46 alopecia, androgenetic, 1 9.9
47 myocardial infarction 9.9
48 hypertension, essential 9.9
49 schizophrenia 9.9
50 prostatic hyperplasia, benign 9.9

Graphical network of the top 20 diseases related to Mungan Syndrome:



Diseases related to Mungan Syndrome

Symptoms & Phenotypes for Mungan Syndrome

Symptoms via clinical synopsis from OMIM:

57
Genitourinary Ureters:
vesicoureteral reflux

Head And Neck Eyes:
ptosis, bilateral

Cardiovascular Vascular:
supravalvular pulmonary stenosis, minimal

Neurologic Peripheral Nervous System:
visceral neuromyopathy

Genitourinary Kidneys:
renal hypoplasia

Cardiovascular Heart:
tricuspid valve regurgitation
ventricular septal defect, membranous
pulmonary valve regurgitation
pulmonary valve stenosis, minimal

Abdomen Gastrointestinal:
visceral neuromyopathy
pseudoobstruction
megaduodenum
barrett esophagus, long-segment
aperistalsis


Clinical features from OMIM:

611376

Human phenotypes related to Mungan Syndrome:

32 (show all 11)
# Description HPO Frequency HPO Source Accession
1 vesicoureteral reflux 32 HP:0000076
2 renal hypoplasia 32 HP:0000089
3 bilateral ptosis 32 HP:0001488
4 pulmonic stenosis 32 HP:0001642
5 abnormality of the autonomic nervous system 32 HP:0002270
6 intestinal pseudo-obstruction 32 HP:0004389
7 tricuspid regurgitation 32 HP:0005180
8 perimembranous ventricular septal defect 32 HP:0011682
9 megaduodenum 32 HP:0030996
10 barrett esophagus 32 HP:0100580
11 hypoperistalsis 32 HP:0100771

Drugs & Therapeutics for Mungan Syndrome

Search Clinical Trials , NIH Clinical Center for Mungan Syndrome

Genetic Tests for Mungan Syndrome

Anatomical Context for Mungan Syndrome

Publications for Mungan Syndrome

Variations for Mungan Syndrome

Expression for Mungan Syndrome

Search GEO for disease gene expression data for Mungan Syndrome.

Pathways for Mungan Syndrome

GO Terms for Mungan Syndrome

Sources for Mungan Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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