Mycetoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: MYC012 MIFTS: 49	Mycetoma Categories: Infectious diseases, Rare diseases
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Aliases & Classifications for Mycetoma

MalaCards integrated aliases for Mycetoma:

Name: Mycetoma ²⁰ ⁵⁸ ⁷⁰ ³²

Madura Foot ²⁰ ⁵⁸

Mycetoma of Foot ⁷⁰

Characteristics:

Orphanet epidemiological data:

⁵⁸

mycetoma
Inheritance: Not applicable; Age of onset: All ages;

Classifications:

MalaCards categories:
Global: Rare diseases Infectious diseases

See all MalaCards categories (disease lists)

ICD10: ³² ³³

Certain infectious and parasitic diseases

Mycoses

Mycetoma

Actinomycetoma

Eumycetoma

Mycetoma, unspecified

Orphanet: ⁵⁸

Rare infectious diseases

External Ids:

ICD10 ³² B47 B47.9

MESH via Orphanet ⁴⁵ D008271

ICD10 via Orphanet ³³ B47.0 B47.1 B47.9

UMLS via Orphanet ⁷¹ C0024449

Orphanet ⁵⁸ ORPHA2583

UMLS ⁷⁰ C0024449 C2355609

Sources

Summaries for Mycetoma

GARD : ²⁰ Mycetoma is a chronic infection that is caused by fungi or actinomycetes ( bacteria that produce filaments, like fungi). The first symptom of the condition is generally painless swelling beneath the skin, which progresses to a nodule (lump) over several years. Eventually, affected people experience massive swelling and hardening of the affected area; skin rupture; and formation of sinus tracts (holes) that discharge pus and grains filled with organisms. Some affected people have no discomfort while others report itching and/or pain. Mycetoma is rare in the United States, but is commonly diagnosed in Africa, Mexico and India. In these countries, it occurs most frequently in farmers, shepherds, and people living in rural areas. Frequent exposure to penetrating wounds by thorns or splinters is a risk factor. Treatment varies based on the cause of the condition and may include antibiotics or antifungal medications.

MalaCards based summary : Mycetoma, also known as madura foot, is related to eumycotic mycetoma and aspergillosis. An important gene associated with Mycetoma is THBS4 (Thrombospondin 4), and among its related pathways/superpathways are NF-kappaB Signaling and Insulin receptor recycling. The drugs Guaifenesin and Phenylpropanolamine have been mentioned in the context of this disorder. Affiliated tissues include bone, lymph node and tongue, and related phenotypes are subcutaneous nodule and recurrent bacterial skin infections

Wikipedia : ⁷³ Mycetoma is a chronic subcutaneous infection caused by aerobic actinomycetic bacteria (actinomycetoma)... more...

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Related Diseases for Mycetoma

Diseases related to Mycetoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 353)

#	Related Disease	Score	Top Affiliating Genes
1	eumycotic mycetoma	32.8	TPT1 CHIT1
2	aspergillosis	30.2	IL10 CXCL8 CCL5
3	fungal infectious disease	29.9	IL17A IL10 CXCL8
4	lipoid congenital adrenal hyperplasia	29.9	HSD3B1 CYP19A1 CYP17A1
5	peritonitis	29.8	IL10 CXCL8 CR1
6	filariasis	29.7	NOS2 IL10 CHIT1 CCL5
7	subcutaneous mycosis	29.6	IL17A IL10
8	candidiasis	29.4	IL17A IL10 CXCL8 CHIT1
9	endocarditis	29.4	IL17A IL10 CXCL8
10	bone inflammation disease	29.4	MMP9 IL17A IL10 CXCL8
11	leprosy 3	29.3	IL17A IL10 CXCL8
12	silicosis	29.0	IL17A IL10 CXCL8
13	nasal cavity disease	28.7	IL17A IL10 CXCL8 CCL5
14	keratitis, hereditary	28.6	MMP9 IL17A IL10 CYP1B1 CXCL8
15	interstitial lung disease	28.5	MMP9 IL17A IL10 CXCL8 CCL5
16	lung disease	28.4	MMP9 IL17A IL10 CXCR2 CXCL8 CCL5
17	pneumonia	28.3	IL17A IL10 CXCR2 CXCL8 CCL5
18	rhinitis	28.3	TPT1 IL17A IL10 CXCL8 CCL5
19	cystic fibrosis	28.2	NOS2 MMP9 IL17A IL10 CXCL8
20	actinomycosis	11.2
21	mixed epithelial stromal tumour	10.3	CYP1B1 COMT
22	chromoblastomycosis	10.3
23	transsexualism	10.3	CYP19A1 CYP17A1
24	whiplash	10.3	COMT CCL5
25	osteomyelitis	10.2
26	nocardiosis	10.2
27	gender identity disorder	10.2	CYP19A1 CYP17A1
28	internal hemorrhoid	10.2	NOS2 MMP9
29	disease by infectious agent	10.2
30	testicular germ cell tumor	10.2	CYP1B1 CYP19A1 COMT
31	dermatomycosis	10.2	TPT1 CHIT1
32	chronic granulomatous disease	10.2
33	46,xy sex reversal 2	10.2	HSD3B1 CYP19A1 CYP17A1
34	disorder of sexual development	10.2	HSD3B1 CYP19A1 CYP17A1
35	bacterial infectious disease	10.2
36	baritosis	10.1	NOS2 CXCL8
37	denture stomatitis	10.1	CXCL8 CSN1S1
38	pseudohermaphroditism	10.1	HSD3B1 CYP19A1 CYP17A1
39	leiomyoma	10.1	CYP19A1 CYP17A1 COMT
40	cardiac rupture	10.1	MMP9 CXCL8
41	cow milk allergy	10.1	IL10 CSN1S1
42	sporotrichosis	10.1
43	dermatophytosis	10.1
44	posttransplant acute limbic encephalitis	10.1
45	mammographic density	10.1	CYP1B1 CYP19A1 CYP17A1 COMT
46	enterocolitis	10.1	IL10 CXCL8
47	phaeohyphomycosis	10.1
48	amelogenesis imperfecta, type ig	10.1	HSD3B1 CYP1B1 CYP19A1
49	estrogen-receptor negative breast cancer	10.1	CYP1B1 CYP19A1 CXCL8
50	asperger syndrome	10.1	CYP1B1 CYP19A1 CYP17A1 COMT

Graphical network of the top 20 diseases related to Mycetoma:

Sources

Symptoms & Phenotypes for Mycetoma

Human phenotypes related to Mycetoma:

⁵⁸ ³¹ (show all 30)

#	Description	HPO Frequency	Orphanet Frequency	HPO Source Accession
1	subcutaneous nodule ⁵⁸ ³¹	frequent (33%)	Frequent (79-30%)	HP:0001482
2	recurrent bacterial skin infections ⁵⁸ ³¹	frequent (33%)	Frequent (79-30%)	HP:0005406
3	recurrent fungal infections ⁵⁸ ³¹	frequent (33%)	Frequent (79-30%)	HP:0002841
4	prominent superficial veins ⁵⁸ ³¹	frequent (33%)	Frequent (79-30%)	HP:0001015
5	stiff skin ⁵⁸ ³¹	frequent (33%)	Frequent (79-30%)	HP:0030053
6	structural foot deformity ⁵⁸ ³¹	frequent (33%)	Frequent (79-30%)	HP:0010219
7	cobblestone-like hyperkeratosis ⁵⁸ ³¹	frequent (33%)	Frequent (79-30%)	HP:0031288
8	osteoporosis ⁵⁸ ³¹	occasional (7.5%)	Occasional (29-5%)	HP:0000939
9	abnormality of the lymphatic system ⁵⁸ ³¹	occasional (7.5%)	Occasional (29-5%)	HP:0100763
10	osteomyelitis ⁵⁸ ³¹	occasional (7.5%)	Occasional (29-5%)	HP:0002754
11	abnormality of the hand ⁵⁸ ³¹	occasional (7.5%)	Occasional (29-5%)	HP:0001155
12	abnormality of the knee ⁵⁸ ³¹	occasional (7.5%)	Occasional (29-5%)	HP:0002815
13	cutaneous cyst ⁵⁸ ³¹	occasional (7.5%)	Occasional (29-5%)	HP:0025245
14	abnormality of forearm bone ⁵⁸ ³¹	occasional (7.5%)	Occasional (29-5%)	HP:0040072
15	abnormal form of the vertebral bodies ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0003312
16	back pain ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0003418
17	bone cyst ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0012062
18	vertebral compression fractures ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0002953
19	painless fractures due to injury ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0002661
20	scalp tenderness ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0100809
21	paraplegia ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0010550
22	pathologic fracture ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0002756
23	pelvic mass ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0031501
24	abdominal mass ⁵⁸ ³¹	very rare (1%)	Very rare (<4-1%)	HP:0031500
25	abnormal thorax morphology ³¹	very rare (1%)		HP:0000765
26	abnormality of the thorax ⁵⁸		Very rare (<4-1%)
27	abnormality of the nervous system ⁵⁸		Very rare (<4-1%)
28	abnormal appendicular skeleton morphology ⁵⁸		Occasional (29-5%)
29	abnormal bone structure ⁵⁸		Frequent (79-30%)
30	abnormality of head or neck ⁵⁸		Very rare (<4-1%)

Sources

Drugs & Therapeutics for Mycetoma

Drugs for Mycetoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Guaifenesin

Approved, Investigational, Vet_approved

Phase 4

93-14-1

3516

Synonyms:

3-(2-Methoxyphenoxy)-1,2-propanediol

3-(O-Methoxyphenoxy)-1,2-propanediol

3-(O-Methoxyphenoxy)-propanediol-1,2

3-O-Methoxyphenoxypropane 1:2-diol

Actifed C

Aeronesin

a-Glyceryl guaiacol ether

a-Glyceryl guaiacolate ether

alpha-Glyceryl guaiacol ether

alpha-Glyceryl guaiacolate ether

Amonidren

Amonidrin

Aresol

Benylin-e

Breonesin

Bronchol

Ether, guaiacol glyceryl

Glycerin ether

Glycerin guaiacolate

Glycero-guaiacol ether

Glycerol a-(2-methoxyphenyl) ether

Glycerol a-(O-methoxyphenyl)ether

Glycerol a-guaiacyl ether

Glycerol a-guiacyl ether

Glycerol a-monoguaiacol ether

Glycerol guaiacolate

Glycerol mono(2-methoxyphenyl) ether

Glycerol-a-guajakolether

Glycerol-alpha-guajakolether

Glyceryl ether, guaiacol

Glyceryl guaiacol

Glyceryl guaiacol ether

Glyceryl guaiacolate

Glyceryl guaiacolate ether

Glyceryl guaiacyl ether

Glyceryl guaicolate

Glyceryl guiacolate

Glycerylguaiacol

Guaiacol glycerol ether

Guaiacol glyceryl ether

Guaiacolate, glycerol

Guaiacolglicerinetere

Guaiacuran

Guaiacurane

Guaiacyl glyceryl ether

Guaiamar

Guaianesin

Guaicol glycerine ether

Guaicol glyceryl ether

Guaifenesin

Guaifenesina

Guaifenesine

guaiphenesin

Guaiphenesin

Guaiphenesine

Guaiphenezine

Guaiphesin

Guiatuss

Humibid

Hustosil

Hytuss

Methoxypropanediol

Methphenoxydiol

Metossipropandiolo

O-Methoxyphenyl glyceryl ether

Organidin NR

p-Cresyl acetate

Pneumomist

Propanosedyl

Reduton

Robitussin

Scott tussin

Scott-tussin

ScottTussin

Phenylpropanolamine

Approved, Vet_approved, Withdrawn

Phase 4

14838-15-4

26934

Synonyms:

(-)-Norephedrin

(-)-Norephedrine

(.+-.)-Norephedrine

(+-)-Norephedrin

(+)-Norephedrine

(+-)-Norephedrine

(+-)-Phenylpropanolamine

(+/-)-Norephedrin

(1R,2S)-Norephedrine

.psi.-Norephedrine

134-60-1

14838-15-4

16960-27-3

1926-74-5

27818-48-0

282553_ALDRICH

317500_ALDRICH

36393-56-3

36393-57-4

37577-07-4

37577-28-9

48115-38-4

492-39-7

492-41-1

6891-23-2

700-65-2

74530_FLUKA

AB00375975

AB1001936

AC1L1C6K

AC1L1IYB

AC1L1UWH

AC1L4QZI

AC1Q59PM

Acutrim

Ami-Tex

AR-1J0987

AR-1J0988

BIDD:GT0376

BPBio1_000361

BRN 2802895

BRN 3196918

BSPBio_000327

BSPBio_003292

C02343

C07911

C16719

C9H13NO

Cathina

Cathine

Cathine [INN]

Cathinum

Cathinum [INN-Latin]

CHEBI:327494

CHEMBL136560

CID10297

CID162265

CID26934

CID4786

Codimal

Conex

Contuss

D-(+)-Norephedrine

D08368

DB00397

DEA No. 1230

Despec

Dexatrim

DivK1c_000795

DivK1c_007030

dl-Norephedrine

DL-Norephedrine

DL-Phenylpropanolamine

D-Norephedrine

d-Norpseudoephedrine

d-Nor-psi-ephedrine

Dura-Vent

EINECS 207-754-1

EINECS 207-755-7

EINECS 211-850-9

EINECS 238-900-2

EINECS 253-014-6

Exponcit

Fansia

Fansia (TN)

Fenilpropanolamina

Fugoa

Fugoa Depot

Gentab

Guaipax

HMS2090P12

HSDB 6485

Hydriatine

Hydrochloride, phenylpropanolamine

I01-8913

I01-8924

IDI1_000795

Katine

KBio1_000795

KBio1_001974

KBio2_001583

KBio2_004151

KBio2_006719

KBio3_001778

KBio3_002512

KBioGR_001385

KBioGR_001950

KBioSS_001583

L-(-)-Norephedrine

L001077

l-Norephedrine

L-NOREPHEDRINE

l-Nor-psi-ephedrin

l-Nor-psi-ephedrine

L-Phenyl propanolamine

LS-176795

LS-97284

LS-97285

LS-97461

LS-97462

Minusine

MolPort-001-769-340

MolPort-001-788-006

MolPort-001-794-194

MolPort-001-794-233

Mucorama

Mucron

Mydriatin

Myminic

NCGC00178157-01

NCGC00178157-02

NINDS_000795

Nobese

Nolex

Norephedrine

Norpseudoephedrine

NSC 17704

NSC 9920

NSC120735

NSC17704

NSC9920

Obestat

Partuss

PDSP1_001348

PDSP1_001349

PDSP1_001354

PDSP2_001332

PDSP2_001333

PDSP2_001338

Phenoxine

Phenyldrine

Phenylfenesin

Phenylpropanolamin

Phenylpropanolamina

phenylpropanolamine

Phenylpropanolamine

Phénylpropanolamine

Phenylpropanolamine hydrochloride

Phenylpropanolaminum

PPA

Prestwick_388

Prestwick0_000324

Prestwick1_000324

Prestwick2_000324

Prestwick3_000324

Prolamine

Propadrine

Propagest

Pseudonorephedrine

psi-Norephedrine

Rhindecon

Rhymed

Snaplets

SPBio_000051

SPBio_000471

SPBio_002248

SpecPlus_000934

Spectrum_001103

Spectrum2_000016

Spectrum2_000516

SPECTRUM2300253

Spectrum3_000889

Spectrum3_001706

Spectrum4_000983

Spectrum4_001685

Spectrum5_000330

Spectrum5_001156

Super Odrinex

TAVIST-D

Triaminic DM

ULR

UNII-33RU150WUN

UNII-E1L4ZW2F8O

USAF CS-6

Vanex

WLN: ZY1&YQR

WLN: ZY1&YQR -L

Itraconazole

Approved, Investigational

Phase 4

84625-61-6

55283

Synonyms:

(+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one

(+/-)-1-[( R *)- sec -butyl]-4-[ p -[4-[ p -[[(2 R *,4 S *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-(DELTA) 2 1,2,4-triazolin-5-one mixture with (+/-)-1-[( R *)- sec -butyl]-4-[ p -[4- [ p -[[(2 S *,4 R *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl] phenyl]-(DELTA) 2 -1,2,4-triazolin-5-one

(1)-cis-4-(4-(4-(4-((2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2,4-dihydro-2-sec-butyl-3H-1,2,4-triazol-3-one

2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one

2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one

2-butan-2-yl-4-[4-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one

2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one

3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)

4-(4-{4-[4-({[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}oxy)phenyl]piperazin-1-yl}phenyl)-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

84604-65-9

84625-61-6

AC1L1GQ5

AC1L1IRU

AC1OCEL7

AC1Q6EZ3

AC-542

AKOS000280875

Ambap84625-61-6

BIDD:GT0796

BRN 6042047

C35H38Cl2N8O4

Canadiol

CHEBI:6076

CHEMBL22587

CHEMBL882

CID3793

CID55283

CID6917738

CID9961741

cis-Itraconazole

CPD000058959

D00350

DB01167

EINECS 283-347-2

FT-0082511

HMS2051K14

HMS2090M20

Hyphanox

I01-1043

I0732

Intraconazole

ITC

ITCZ

Itraconazol

Itraconazol [Spanish]

itraconazole

Itraconazole

Itraconazole & Bovine Lactoferrin

Itraconazole & Nyotran

Itraconazole & Nyotran(Liposomal Nystatin)

Itraconazole (JAN/USAN)

Itraconazole [USAN:BAN:INN:JAN]

Itraconazole janssen brand

Itraconazole oral solution

Itraconazolum

Itraconazolum [Latin]

Itrizole

Itrizole (TN)

ITZ

Janssen brand OF itraconazole

Janssen cilag brand OF itraconazole

Janssen-cilag brand OF itraconazole

LS-1843

MLS000028582

MLS000759472

MLS000863291

MLS001148245

MolPort-000-883-864

MolPort-003-848-295

NCGC00089812-03

Oriconazole

Oriconazole, R51211, Sporanox

Orungal

Prokanazol

R 51211

R-51211

S2476_Selleck

SAM001246679

Sempera

SMR000058959

Spherazole

Sporal

Sporanos

Sporanox

Sporanox (TN)

Sporonox

TL8005525

Triasporn

UNII-304NUG5GF4

Miconazole

Approved, Investigational, Vet_approved

Phase 4

22916-47-8

4189

Synonyms:

(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole

1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole

1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole

1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole

1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole

1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole

1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole

1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

22832-87-7 (NITRATE)

22916-47-8

75319-47-0

AB00053500

AC1L1HM1

Aflorix(nitrate)

AKOS001574474

Albistat(nitrate)

Andergin(nitrate)

BPBio1_000279

BRD-A82396632-001-03-0

BRD-A82396632-008-02-7

Brentan

BRN 0965511

BSPBio_000253

BSPBio_002033

CCRIS 7924

CHEBI:6923

CHEMBL91

CID4189

Conofite(nitrate)

CPD-4501

D00416

Dactarin

Daktarin IV

DB01110

DivK1c_000156

EINECS 245-324-5

Epi-Monistat(nitrate)

Esteve brand OF miconazole

Femizol-M

Florid(nitrate)

Gyno-Daktar(nitrate)

HMS1568M15

HMS2090B21

I14-14342

IDI1_000156

imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)

Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)

Janssen cilag brand OF miconazole

Janssen-cilag brand OF miconazole

Johnston and johnston brand OF miconazole nitrate

KBio1_000156

KBio2_001445

KBio2_004013

KBio2_006581

KBio3_001533

KBioGR_000581

KBioSS_001445

Lotrimin AF(nitrate)

LS-78378

MCZ

Micantin (nitrate)

Miconasil nitrate

Miconasil Nitrate

Miconazol

Miconazol [INN-Spanish]

miconazole

Miconazole

Miconazole (JP15/USP/INN)

Miconazole [USAN:BAN:INN:JAN]

Miconazole 3

Miconazole 3 Combination Pack

Miconazole 7 Combination Pack

Miconazole esteve brand

Miconazole janssen-cilag brand

Miconazole nitrate

Miconazole nitrate salt

Miconazole-7

Miconazolo

Miconazolo [DCIT]

Miconazolum

Miconazolum [INN-Latin]

Micozole

Minostate

MJR 1762

MLS002222203

MolPort-002-557-553

Monazole 7

Monista (nitrate)

Monistat

Monistat (TN)

Monistat 1 Combination Pack

Monistat 3 Dual-Pak

Monistat 3 Vaginal Ovules

Monistat 5 Tampon

Monistat 7 Dual-Pak

Monistat 7 Vaginal Suppositories

Monistat Dual- PAK

Monistat IV

Monistat iv (TN)

Monistat-Derm

NCI60_001353

NCI60_001380

NINDS_000156

Nitrate, miconasil

Nitrate, miconazole

Novo-Miconazole Vaginal Ovules

NSC 170986

NSC169434

NSC170986

Oprea1_091955

Prestwick_335

Prestwick0_000067

Prestwick1_000067

Prestwick2_000067

Prestwick3_000067

R 18134

R-14,889

SMR001307249

SPBio_000976

SPBio_002174

Spectrum_000965

Spectrum2_001048

Spectrum3_000507

Spectrum4_000061

Spectrum5_001297

STK834405

STOCK1S-93556

UNII-7NNO0D7S5M

Vusion

Zimycan

Clotrimazole

Approved, Vet_approved

Phase 4

23593-75-1

2812

Synonyms:

(Chlorotrityl)imidazole

1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole

1-(a-(2-Chlorophenyl)benzhydryl)imidazole

1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole

1-(O-Chloro-a,a-diphenylbenzyl)imidazole

1-(O-Chloro-alpha,alpha-diphenylbenzyl)imidazole

1-(o-Chlorotrityl)imidazole

1-(O-Chlorotrityl)imidazole

1-(o-Chloro-α,α-diphenylbenzyl)imidazole

1-(O-Chloro-α,α-diphenylbenzyl)imidazole

1-(α-(2-Chlorophenyl)benzhydryl)imidazole

1-(Α-(2-chlorophenyl)benzhydryl)imidazole

117829-71-7

23593-75-1

33894_FLUKA

33894_RIEDEL

3ACDFDF8-38E3-4368-85D0-BDF8AE1E6591

AB00051951

AC1L1EIW

AC-279

B 5097

BAY 5097

Bay b 5097

BAY b 5097

Bay b 9057

BAY b5097

BAY-5097

Bay-B 5097

BAYb 5097

Bayer brand 1 OF clotrimazole

Bayer Brand 1 of Clotrimazole

Bayer brand 2 OF clotrimazole

Bayer Brand 2 of Clotrimazole

BIDD:GT0450

BIDD:PXR0036

Bio-0442

BPBio1_000126

BRN 0622318

BSPBio_000114

BSPBio_002057

C 6019

C06922

C22H17ClN2

C6019_SIGMA

Canesten

Canesten 1-day cream combi-pak

Canesten 1-Day Cream Combi-Pak

Canesten 1-day therapy

Canesten 1-Day Therapy

Canesten 3-day therapy

Canesten 3-Day Therapy

Canesten 6-day therapy

Canesten 6-Day Therapy

Canesten combi-pak 1-day therapy

Canesten Combi-Pak 1-Day Therapy

Canesten combi-pak 3-day therapy

Canesten Combi-Pak 3-Day Therapy

Canesten cream

Canesten Cream

Canesten solution

Canesten Solution

Canestene

Canestine

Canifug

CAS-23593-75-1

CCRIS 6245

CHEBI:3764

CHEMBL104

Chlotrimazole

CID2812

Cimitidine

Clomatin

Clotrimaderm

Clotrimaderm cream

Clotrimazol

Clotrimazol [INN-Spanish]

clotrimazole

Clotrimazole

Clotrimazole (JP15/USP/INN)

Clotrimazole [USAN:INN:BAN:JAN]

Clotrimazole schering brand

Clotrimazole Schering Brand

Clotrimazolum

Clotrimazolum [INN-Latin]

clotrimeizol

CPD000058306

CPD-8926

Cutistad

D00282

D003022

DB00257

Desamix F

DivK1c_000665

DRG-0072

EINECS 245-764-8

Empecid

Esparol

EU-0100315

FB 5097

FB b 5097

Fem care

Fem Care

FemCare

Gino-Lotremine

Gyne lotrimin

Gyne-lotrimin

Gyne-Lotrimin

Gyne-lotrimin 3

Gyne-Lotrimin 3

Gyne-lotrimin 3 combination pack

Gyne-Lotrimin 3 Combination Pack

Gyne-lotrimin combination pack

Gyne-Lotrimin Combination Pack

Gyne-lotrimin3

Gyne-lotrimin3 combination pack

Gynix

HMS1568F16

HMS1920O21

HMS2051E11

HMS2091G10

HMS502B07

HSDB 3266

I01-3474

IDI1_000665

Kanesten

KBio1_000665

KBio2_001823

KBio2_004391

KBio2_006959

KBio3_001277

KBioGR_000850

KBioSS_001823

Klotrimazole

Lopac0_000315

Lopac-C-6019

Lotrimax

Lotrimin

Lotrimin (TN)

Lotrimin af

Lotrimin Af

Lotrimin af cream

Lotrimin AF Cream

Lotrimin af jock-itch cream

Lotrimin AF Jock-Itch Cream

Lotrimin af lotion

Lotrimin AF Lotion

Lotrimin af solution

Lotrimin AF Solution

Lotrimin cream

Lotrimin Cream

Lotrimin lotion

Lotrimin Lotion

Lotrimin solution

Lotrimin Solution

Lotrisone

LS-78271

MLS000028502

MLS000758243

MLS001423972

MolPort-002-557-756

mono-Baycuten

Monobaycuten

Mono-baycuten

Mycelax

Mycelex

Mycelex (TN)

Mycelex 7

Mycelex cream

Mycelex Cream

Mycelex g

Mycelex G

Mycelex otc

Mycelex OTC

Mycelex solution

Mycelex Solution

Mycelex troches

Mycelex Troches

Mycelex twin pack

Mycelex Twin Pack

Mycelex: mycosporinrimazole

Mycelex: MycosporinRimazole

Mycelex-7

Mycelex-7 combination pack

Mycelex-7 Combination Pack

Mycelex-g

Mycelex-G

Myclo cream

Myclo Cream

Myclo solution

Myclo Solution

Myclo spray solution

Myclo Spray Solution

Myclo-gyne

Myclo-Gyne

Mycofug

Mycosporin

Mykosporin

Nalbix

NCGC00015251-01

NCGC00015251-02

NCGC00015251-03

NCGC00015251-09

NCGC00093761-01

NCGC00093761-02

NCGC00093761-03

NCGC00093761-04

NCGC00093761-05

NCGC00093761-06

nchembio.65-comp9

nchembio790-comp30

NCIMech_000609

Neo-zol cream

Neo-Zol Cream

NINDS_000665

NSC 257473

NSC257473

Otomax

Pan-Fungex

Pedisafe

Prestwick_120

Prestwick0_000267

Prestwick1_000267

Prestwick2_000267

Prestwick3_000267

QTL1_000024

Rimazole

S1606_Selleck

SAM001247056

Schering brand OF clotrimazole

Schering Brand of Clotrimazole

SMR000058306

SPBio_000176

SPBio_002333

Spectrum_001343

SPECTRUM1500200

Spectrum2_000128

Spectrum3_000359

Spectrum4_000295

Spectrum5_000781

Stiemazol

STK700023

Tibatin

Trimysten

Trivagizole 3

UNII-G07GZ97H65

Veltrim

ZINC03807804

Cytochrome P-450 CYP3A Inhibitors

Phase 4

Hydroxyitraconazole

Phase 4

108222

Cytochrome P-450 Enzyme Inhibitors

Phase 4

Hormone Antagonists

Phase 4

Chlorpheniramine, phenylpropanolamine drug combination

Phase 4

Antitussive Agents

Phase 4

Hormones

Phase 4

Anti-Infective Agents

Phase 4

Antifungal Agents

Phase 4

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	A RANDOMIZED CONTROLLED STUDY OF ITRACONAZOLE IN CHRONIC CAVITARY PULMONARY ASPERGILLOSIS	Completed	NCT01259336	Phase 4	Itraconazole;treatment in cavitary pulmonary aspergillosis
2	A Randomized, Double Blind Phase II Proof-of-Concept Superiority Trial of Fosravuconazole 200 mg or 300 mg Weekly Dose Versus Itraconazole 400 mg Daily, All Three Arms in Combination With Surgery, in Patients With Eumycetoma in Sudan	Unknown status	NCT03086226	Phase 2	Fosravuconazole;Itraconazole
3	Studying the Tissue Microenvironment Signatures of the Mycetoma Granuloma	Completed	NCT04401969

Search NIH Clinical Center for Mycetoma

Sources

Genetic Tests for Mycetoma

Sources

Anatomical Context for Mycetoma

MalaCards organs/tissues related to Mycetoma:

⁴⁰

Bone, Lymph Node, Tongue, Pituitary, Bone Marrow, Colon, Prostate

Sources

Publications for Mycetoma

Articles related to Mycetoma:

(show top 50) (show all 1675)

#	Title	Authors	PMID	Year
1	Development of E1224 by leveraging a strategic partnership for the medicines creation against neglected tropical diseases. ⁶¹	Hata K	33370607	2021
2	Localized cutaneous infection caused by Scedosporium apiospermum: Report of a case diagnosed on cytology. ⁶¹	Agarwal R...Jain S	33074579	2021
3	Estimates of serious fungal infection burden in Côte d'Ivoire and country health profile. ⁶¹	Koffi D...Denning DW	33259981	2021
4	First report of cutaneous mycetoma by Paecilomyces variotii and the successful treatment with combined itraconazole and terbinafine along with resection surgeries. ⁶¹	Criado PR...da Matta VLR	33759175	2021
5	Pulmonary Madurella mycetomatis mycetoma secondary to knee eumycetoma, Senegal. ⁶¹	Diongue K...Ndiaye D	33764976	2021
6	Mycetoma spatial geographical distribution in the Eastern Sennar locality, Sennar State, Sudan. ⁶¹	Ganawa ETS...Fahal AH	33675358	2021
7	Invasive, aggressive mastoid bone eumycetoma: a treatment challenge. ⁶¹	Yosif AA...Fahal AH	33682008	2021
8	Mycetoma in West Africa. ⁶¹	Oladele RO...van de Sande WWJ	33728466	2021
9	A possible role for ticks in the transmission of Madurella mycetomatis in a mycetoma-endemic village in Sudan. ⁶¹	Azrag RS...Fahal AH	33690861	2021
10	Distribution of invasive fungal infections: Molecular epidemiology, etiology, clinical conditions, diagnosis and risk factors: A 3-year experience with 490 patients under intensive care. ⁶¹	Borjian Boroujeni Z...Raiesi O	33212195	2021
11	Madura foot: Actinomycetoma of the calcaneum. ⁶¹	Jolu A...Rosine N	33689841	2021
12	A study of 87 mycetoma patients seen at three health facilities in Nouakchott, Mauritania. ⁶¹	Kebe M...Fahal A	33580966	2021
13	Mycetoma in Sudan: experience of the Mycetoma Project from 1968 to 1991. ⁶¹	Mahgoub E	33561267	2021
14	Mycetoma: the journey from neglect to recognition as a neglected tropical disease. ⁶¹	Fahal AH	33539538	2021
15	Mycetoma imaging: the best practice. ⁶¹	Bahar ME...Fahal AH	33537774	2021
16	In vitro susceptibility testing for black grain eumycetoma causative agents. ⁶¹	van de Sande WWJ	33537781	2021
17	A case of false identity: Primary cutaneous diffuse large B-cell lymphoma masquerading as Madura Foot. ⁶¹	Ibrahim S...Pai K	33573513	2021
18	The impact of COVID-19 pandemic on AIDS-related mycoses and fungal neglected tropical diseases: Why should we worry? ⁶¹	Nargesi S...Hedayati MT	33561159	2021
19	Case Report: Coral Reef Pathogen Aspergillus sydowii Causing Black Grain Mycetoma: A Review. ⁶¹	Vera-Cabrera L...Ocampo-Candiani J	33399044	2021
20	Melanin production in coelomycetous agents of black grain eumycetoma. ⁶¹	Lim W...van de Sande WWJ	33463687	2021
21	Actinomycetoma laboratory-based diagnosis: a mini-review. ⁶¹	Siddig EE...Fahal AH	33449118	2021
22	Metagenomics of black grains: new highlights in the understanding of eumycetoma. ⁶¹	Santona A...Fahal AH	33449116	2021
23	Multiple extensive Madurella mycetomatis eumycetoma lesions: a case report and review of the literature. ⁶¹	Zaid DM...Fahal AH	33406268	2021
24	Mycetoma caused by Microascus gracilis: a novel agent of human eumycetoma in Sudan. ⁶¹	Mhmoud NA...Fahal AH	33515449	2021
25	Mycetoma and the Community Dermatology Program, Mexico. ⁶¹	Roberto E...Hay R	33479763	2021
26	The challenges of recruitment in clinical trials in developing countries: the Mycetoma Research Centre experience. ⁶¹	Omer RF...Fahal AH	33484566	2021
27	Deep mycoses and pseudomycoses of the foot: a single-center retrospective study of 160 cases, in a tertiary-care center in Mexico. ⁶¹	Bonifaz A...Gonzalez GM	33453613	2021
28	Extensive perineal Actinomadura pelletieri actinomycetoma-induced urethral stricture: a rare complication. ⁶¹	Bakheet OE...Fahal AH	33399848	2021
29	Abdominal wall actinomycotic mycetoma involving the bowel: a rare entity. ⁶¹	Sharma AK...Ranjan KR	33504519	2021
30	Mycetoma in Moshi, Tanzania. ⁶¹	Mavura D...Hay R	33438021	2021
31	Compressive epidural collection as an unusual complication of FESS for a pediatric mycetoma. ⁶¹	Capek S...Syed HR	32409960	2021
32	Massive complicated secondary inguinal mycetoma: a case series. ⁶¹	Ezaldeen EA...Fahal AH	33476389	2021
33	Surgery in mycetoma-endemic villages: unique experience. ⁶¹	Mohamed ESW...Fahal AH	33515452	2021
34	Scedosporium apiospermum lung disease in a patient with nontuberculous mycobacteria. ⁶¹	Ogata H...Okamoto I	33318800	2021
35	Complete Genome Sequence of Streptomyces Phage Salutena. ⁶¹	Kim J...Burrowes B	33414317	2021
36	Development of the Global Mycetoma Working Group. ⁶¹	Traxler RM...Chiller T	33320935	2020
37	Mycetoma - a long journey out of the shadows. ⁶¹	Hay RJ...Fahal AH	33313922	2020
38	New molecular marker for phylogenetic reconstruction of black yeast-like fungi (Chaetothyriales) with hypothetical EIF2AK2 kinase gene. ⁶¹	Assuncao CB...Caligiorne RB	33213783	2020
39	Human actinomycetoma caused by Actinomadura mexicana in Sudan: the first report. ⁶¹	Siddig EE...Fahal AH	33382899	2020
40	A Short Tandem Repeat Assay for Studying Genetic Variation in Madurella mycetomatis (MmySTR). ⁶¹	Nyuykonge B...Klaassen CHW	33298608	2020
41	Severely stigmatised skin neglected tropical diseases: a protocol for social science engagement. ⁶¹	Zaman S...Davey G	33324991	2020
42	Scedosporium Cell Wall: From Carbohydrate-Containing Structures to Host-Pathogen Interactions. ⁶¹	Rollin-Pinheiro R...Barreto-Bergter E	32990888	2020
43	Nasal Gel Loaded with Amphotericin Nanotransferosomes as Antifungal Treatment for Fungal Sinusitis. ⁶¹	Hosny KM...Alhakamy NA	33379314	2020
44	Madura foot in a developed tropical country. ⁶¹	Wang SSY	33075524	2020
45	Mycetoma caused by Microsporum canis in a patient with renal transplant: A case report and review of the literature. ⁶¹	Teo TSP...Warner MS	33217133	2020
46	Molecular identification of Actinomadura madurae isolated from a patient originally from Algeria; observations from a case report. ⁶¹	Izri A...Akhoundi M	33176717	2020
47	Mycetoma - a history of the first contributions to the description of the disease and its pathogenesis. ⁶¹	Hay RJ	33205160	2020
48	The use of traditional medicines among mycetoma patients. ⁶¹	Kunna E...Fahal A	33247308	2020
49	Research capacity building with mycetoma as the central research challenge. ⁶¹	Davey G...Newport MJ	33210120	2020
50	Inducible nitric oxide synthase blockade with aminoguanidine, protects mice infected with Nocardia brasiliensis from actinomycetoma development. ⁶¹	Salinas-Carmona MC...Vazquez-Marmolejo AV	33091049	2020

Sources

Genes for Mycetoma

Genes related to Mycetoma (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	THBS4	Thrombospondin 4	Protein Coding	6.97	GeneCards inferred via : Publications (show sections)
2	CHIT1	Chitinase 1	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
3	COMT	Catechol-O-Methyltransferase	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
4	CR1	Complement C3b/C4b Receptor 1 (Knops Blood Group)	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
5	CSN1S1	Casein Alpha S1	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
6	CYP17A1	Cytochrome P450 Family 17 Subfamily A Member 1	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
7	CYP19A1	Cytochrome P450 Family 19 Subfamily A Member 1	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
8	CYP1B1	Cytochrome P450 Family 1 Subfamily B Member 1	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
9	HSD3B1	Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- And Steroid Delta-Isomerase 1	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
10	MMP9	Matrix Metallopeptidase 9	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
11	NOS2	Nitric Oxide Synthase 2	Protein Coding	6.77	GeneCards inferred via : Publications (show sections)
12	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	6.42	GeneCards inferred via : Publications (show sections)
13	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	6.42	GeneCards inferred via : Publications (show sections)
14	CXCR2	C-X-C Motif Chemokine Receptor 2	Protein Coding	6.42	GeneCards inferred via : Publications (show sections)
15	IL10	Interleukin 10	Protein Coding	6.42	GeneCards inferred via : Publications (show sections)
16	IL17A	Interleukin 17A	Protein Coding	6.42	GeneCards inferred via : Publications (show sections)
17	TPT1	Tumor Protein, Translationally-Controlled 1	Protein Coding	6.42	GeneCards inferred via : Publications (show sections)

Sources

Variations for Mycetoma

Sources

Expression for Mycetoma

Search GEO for disease gene expression data for Mycetoma.

Sources

Pathways for Mycetoma

Pathways related to Mycetoma according to GeneCards Suite gene sharing:

(show all 20)

#	Super pathways	Score	Top Affiliating Genes
1	NF-kappaB Signaling ⁴	12.39	TPT1 IL17A IL10 CCL5
2	Insulin receptor recycling ⁶⁵ Show member pathways Collecting duct acid secretion ³⁶ Epithelial cell signaling in Helicobacter pylori infection ³⁶ Iron uptake and transport ⁶⁵ ROS, RNS production in phagocytes ⁶⁵ Transferrin endocytosis and recycling ⁶⁵ Vibrio cholerae infection ³⁶	12.3	NOS2 CXCR2 CXCL8 CCL5
3	Immune response CCR3 signaling in eosinophils ²³ Show member pathways Inhibitory action of Lipoxins on neutrophil migration ²³	12.15	NOS2 CXCR2 CXCL8 CCL5
4	Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions ⁶⁴ Show member pathways Chemokine receptors bind chemokines ⁶⁵ Viral protein interaction with cytokine and cytokine receptor ³⁶	12.11	IL10 CXCR2 CXCL8 CCL5
5	Spinal Cord Injury ¹	11.85	NOS2 MMP9 CXCL8
6	Amoebiasis ³⁶	11.75	NOS2 IL10 CXCL8
7	Rheumatoid arthritis ³⁶	11.7	IL17A CXCL8 CCL5
8	Metabolism of steroid hormones ⁶⁵ Show member pathways Androgen biosynthesis ⁶⁵ Estrogen biosynthesis ⁶⁵ glucocorticoid biosynthesis ¹ Glucocorticoid biosynthesis ⁶⁵ mineralocorticoid biosynthesis ¹ Mineralocorticoid biosynthesis ⁶⁵ Pregnenolone biosynthesis ⁶⁵	11.62	HSD3B1 CYP19A1 CYP17A1
9	Pertussis ³⁶	11.58	NOS2 IL10 CXCL8
10	IgA-Producing B Cells in the Intestine ⁶⁴	11.49	NOS2 IL10 CR1
11	Photodynamic therapy-induced NF-kB survival signaling ¹ Show member pathways Immune response MIF-mediated glucocorticoid regulation ²³	11.43	NOS2 MMP9 CXCL8
12	Lung fibrosis ¹	11.41	MMP9 CXCL8 CCL5
13	Interleukin-4 and 13 signaling ⁶⁵	11.41	NOS2 MMP9 IL17A IL10 CXCL8
14	Androstenedione and testosterone biosynthesis and metabolism p.1 ²³ Show member pathways Estrogen biosynthesis ²³ Estrone metabolism ²³ Steroid Biosynthesis ¹	11.36	HSD3B1 CYP19A1 CYP17A1 COMT
15	Interleukin-10 signaling ⁶⁵	11.27	IL10 CXCL8 CCL5
16	Ovarian steroidogenesis ³⁶	11.27	HSD3B1 CYP1B1 CYP19A1 CYP17A1
17	Malaria ³⁶	11.16	THBS4 IL10 CXCL8 CR1
18	Estrogen metabolism ¹ Show member pathways Estrogen Metabolism Pathway ⁶⁰	11.08	CYP1B1 CYP19A1 COMT
19	Steroid hormone biosynthesis ³⁶ Show member pathways allopregnanolone biosynthesis ¹	10.85	HSD3B1 CYP1B1 CYP19A1 CYP17A1 COMT
20	Syndecan-1-mediated signaling events ¹	10.81	MMP9 CCL5

Sources

GO Terms for Mycetoma

Cellular components related to Mycetoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.28	TPT1 THBS4 MMP9 IL17A IL10 CXCL8
2	organelle membrane	GO:0031090	9.13	CYP1B1 CYP19A1 CYP17A1

Biological processes related to Mycetoma according to GeneCards Suite gene sharing:

(show all 18)

#	Name	GO ID	Score	Top Affiliating Genes
1	inflammatory response	GO:0006954	9.8	NOS2 IL17A CXCR2 CXCL8 CCL5
2	cellular response to interleukin-1	GO:0071347	9.7	IL17A CXCL8 CCL5
3	neutrophil chemotaxis	GO:0030593	9.67	CXCR2 CXCL8 CCL5
4	chemokine-mediated signaling pathway	GO:0070098	9.63	CXCR2 CXCL8 CCL5
5	immune response	GO:0006955	9.63	IL17A IL10 CXCR2 CXCL8 CHIT1 CCL5
6	steroid biosynthetic process	GO:0006694	9.61	HSD3B1 CYP19A1 CYP17A1
7	dendritic cell chemotaxis	GO:0002407	9.58	CXCR2 CCL5
8	nitric oxide biosynthetic process	GO:0006809	9.57	NOS2 CYP1B1
9	negative regulation of G protein-coupled receptor signaling pathway	GO:0045744	9.56	CXCL8 CCL5
10	estrogen biosynthetic process	GO:0006703	9.55	HSD3B1 CYP19A1
11	response to molecule of bacterial origin	GO:0002237	9.54	IL10 CXCL8
12	androgen biosynthetic process	GO:0006702	9.51	HSD3B1 CYP17A1
13	glucocorticoid biosynthetic process	GO:0006704	9.48	HSD3B1 CYP17A1
14	positive regulation of JAK-STAT cascade	GO:0046427	9.43	IL10 CYP1B1 CCL5
15	endothelial cell-cell adhesion	GO:0071603	9.37	THBS4 CYP1B1
16	positive regulation of cellular biosynthetic process	GO:0031328	9.32	CXCL8 CCL5
17	neutrophil activation	GO:0042119	9.13	CXCR2 CXCL8 CCL5
18	cytokine-mediated signaling pathway	GO:0019221	9.1	NOS2 MMP9 IL17A IL10 CXCL8 CCL5

Molecular functions related to Mycetoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	oxidoreductase activity	GO:0016491	9.77	NOS2 HSD3B1 CYP1B1 CYP19A1 CYP17A1
2	monooxygenase activity	GO:0004497	9.5	CYP1B1 CYP19A1 CYP17A1
3	cytokine activity	GO:0005125	9.46	IL17A IL10 CXCL8 CCL5
4	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO:0016705	9.43	CYP1B1 CYP19A1 CYP17A1
5	heme binding	GO:0020037	9.26	NOS2 CYP1B1 CYP19A1 CYP17A1
6	oxygen binding	GO:0019825	8.8	CYP1B1 CYP19A1 CYP17A1

Sources

Sources for Mycetoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Apr-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia