Mycobacterium Abscessus disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: MYC013 MIFTS: 45	Mycobacterium Abscessus Categories: Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Mycobacterium Abscessus

MalaCards integrated aliases for Mycobacterium Abscessus:

Name: Mycobacterium Abscessus ⁵³

Mycobacterium Abscessus Infection ⁵³

M. Abscessus ⁵³

Classifications:

MalaCards categories:
Global: Rare diseases

See all MalaCards categories (disease lists)

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Summaries for Mycobacterium Abscessus

MalaCards based summary : Mycobacterium Abscessus, also known as mycobacterium abscessus infection, is related to mycobacterium chelonae and pneumonia. An important gene associated with Mycobacterium Abscessus is TLR2 (Toll Like Receptor 2), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Azithromycin and Tigecycline have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and testes, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : ⁷⁶ Mycobacterium abscessus complex (MABSC) is a group of rapidly growing, multidrug-resistant... more...

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Related Diseases for Mycobacterium Abscessus

Diseases related to Mycobacterium Abscessus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 156)

#	Related Disease	Score	Top Affiliating Genes
1	mycobacterium chelonae	31.4	CXCL8 TLR2
2	pneumonia	30.6	CXCL8 TLR2 TNF
3	endocarditis	30.5	CXCL8 TLR2 TNF
4	otitis media	30.5	CXCL8 TLR2 TNF
5	lung disease	30.4	CFTR CXCL8 HMOX1 SERPINA1 TLR2 TNF
6	peritonitis	30.4	CXCL8 TLR2 TNF
7	bronchiectasis	30.3	CFTR CXCL8 SERPINA1 TLR2
8	mycobacterium kansasii	30.3	CXCL8 NLRP3 TLR2
9	nontuberculous mycobacterial lung disease	30.2	CFTR TLR2 TNF
10	anterior uveitis	30.1	TLR2 TNF
11	respiratory failure	30.0	CXCL8 SERPINA1 TNF
12	meningitis	29.9	CXCL8 NLRP3 TLR2 TNF
13	macs syndrome	11.3
14	immunodeficiency 28	11.3
15	cystic fibrosis	10.8
16	mycobacterium fortuitum	10.4
17	osteomyelitis	10.4
18	endophthalmitis	10.3
19	lymphadenitis	10.3
20	mycobacterium marinum	10.2	CXCL8 TLR2
21	arthritis	10.2
22	mastitis	10.2
23	fungal keratitis	10.2	CLEC7A TLR2
24	common wart	10.2	CLEC7A CXCL8
25	subcutaneous mycosis	10.2	CLEC7A SYK
26	sebaceous gland disease	10.2	CXCL8 TLR2
27	trench fever	10.1	TLR2 TNF
28	exudative glomerulonephritis	10.1	CXCL8 TNF
29	acute chest syndrome	10.1	CXCL8 HMOX1
30	vulvovaginal candidiasis	10.1	CLEC7A NLRP3 TLR2
31	sinusitis	10.1	CFTR CXCL8
32	tungiasis	10.1	CXCL8 TNF
33	streptococcal toxic-shock syndrome	10.1	CXCL8 TNF
34	rheumatoid arthritis	10.1
35	cataract	10.1
36	keratopathy	10.1
37	scleritis	10.1
38	prostatitis	10.1
39	cervical adenitis	10.1
40	septic arthritis	10.1
41	congenital cytomegalovirus	10.1	TLR2 TNF
42	trichuriasis	10.1	CXCL8 TNF
43	periapical periodontitis	10.1	TLR2 TNF
44	cardiac sarcoidosis	10.1	CXCL8 TNF
45	opisthorchiasis	10.1	CXCL8 TNF
46	clonorchiasis	10.1	CXCL8 TNF
47	crohn's colitis	10.1	CXCL8 TNF
48	meconium aspiration syndrome	10.1	CXCL8 TNF
49	louse-borne relapsing fever	10.1	CXCL8 TNF
50	primary systemic mycosis	10.0	CLEC7A TLR2 TNF

Graphical network of the top 20 diseases related to Mycobacterium Abscessus:

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Symptoms & Phenotypes for Mycobacterium Abscessus

MGI Mouse Phenotypes related to Mycobacterium Abscessus:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	hematopoietic system	MP:0005397	10.02	CFTR CLEC7A HMOX1 IFNGR2 NLRP3 SQSTM1
2	homeostasis/metabolism	MP:0005376	9.96	CFTR CLEC7A HMOX1 IFNGR2 MSRA NLRP3
3	immune system	MP:0005387	9.85	CFTR CLEC7A HMOX1 IFNGR2 NLRP3 SQSTM1
4	liver/biliary system	MP:0005370	9.5	CFTR HMOX1 NLRP3 SQSTM1 SYK TLR2
5	respiratory system	MP:0005388	9.1	CFTR CLEC7A HMOX1 SYK TLR2 TNF

Sources

Drugs & Therapeutics for Mycobacterium Abscessus

Drugs for Mycobacterium Abscessus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Azithromycin

Approved

Phase 4

83905-01-5

55185 447043

Synonyms:

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)13-((2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl)oxy)-1-oxa-6-azacyclopentadecan-15-one

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranoside

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside

121470-24-4

1-Oxa-6-azacyclopentadecan-15-one, 13-((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)-,(2R-(2R*,3S*

75199_FLUKA

83905-01-5

9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A

AC-16014

AC1L9KEG

Aritromicina

Azadose

Azasite

Azenil

Azifast

Azigram

Azimakrol

Azithramycine

azithromycin

Azithromycin & Tumor Necrosis Factor

Azithromycin (AIDS Initiative)

Azithromycin (anhydrous)

Azithromycin dihydrate

Azithromycin monohydrate

Azithromycin Monohydrate

Azithromycin pfizer brand

Azithromycine

Azithromycinum

Azitrocin

Azitromax

Azitromicina

Azitromin

Azythromycin

Bayer brand OF azithromycin dihydrate

BIDD:GT0792

Bio-0676

BRN 5387583

BSPBio_002285

C38H72N2O12

CCRIS 1961

CHEBI:2955

CHEMBL529

CID447043

CP62,993

CP-62993

CPD000471864

DCH3

Dihydrate, azithromycin

DivK1c_000233

DRG-0104

Funk brand OF azithromycin dihydrate

Goxal

Hemomycin

HMS1922G12

HMS2094M11

HMS500L15

HSDB 7205

IDI1_000233

KBio1_000233

KBio2_000787

KBio2_003355

KBio2_005923

KBio3_001505

KBioGR_000731

KBioSS_000787

Lesvi brand OF azithromycin dihydrate

LS-1834

Mack brand OF azithromycin dihydrate

Misultina

MLS001055353

MLS001066331

MLS001201763

MLS001304005

MLS001332499

MLS001332500

MolPort-002-507-426

Monohydrate, azithromycin

NCGC00090753-01

NCGC00090753-02

NINDS_000233

NSC643732

Pfizer brand OF azithromycin

Pfizer brand OF azithromycin dihydrate

Pharmacia brand OF azithromycin dihydrate

SAM002589961

SMR000471864

SPBio_001544

Spectrum_000307

SPECTRUM1503679

Spectrum2_001582

Spectrum3_000653

Spectrum4_000186

Spectrum5_001867

Sumamed

Toraseptol

Tromix

Ultreon

UNII-JTE4MNN1MD

Vinzam

Vita brand OF azithromycin dihydrate

XZ-450

Zentavion

ZIT

Zithromac

Zithromax

Zithromax IV

Zithromycin

Zitromax

Zitromax Avium 600

Zmas

Zmax

Z-Pak

Tigecycline

Approved

Phase 2

220620-09-7

5282044

Synonyms:

(4S,12aS)-4,7-Bis(dimethylamino)-9-{2-[(tert-butyl)amino]acetylamino}-3,10,12,12a-tetrahydroxy-1,11-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide

(4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide

(4S,4AS,5ar,12as)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide

(4S,4aS,5aR,12aS)-9-[(N-tert-butylglycyl)amino]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

121GE002

220620-09-7

9-t-Butylglycylamido minocycline

AC-1798

AC1NQZEU

C12012

CHEBI:149836

CHEMBL1212946

CHEMBL376140

CID5282044

D01079

DB00560

GAR 936

GAR-936

GAR-936,tigecycline

GAR-936,Tigecycline

LS-186580

LS-187002

LS-187782

N-[(5aR,6aS,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-1,10a,12-trihydroxy-8,10,11-trioxo-5a,6,6a,7-tetrahydro-5H-tetracen-2-yl]-2-(tert-butylamino)acetamide

S1403_Selleck

TBG-MINO

Tigeciclina

Tigecycline

Tigecycline (JAN/USAN)

Tigecycline [USAN]

Tigecyclinum

Tigilcycline

Tygacil

Tygacil (TN)

Tygacil(TM)

Tygacil, GAR-936, WAY-GAR-936, TBG-MINO, Tigecycline

UNII-70JE2N95KR

WAY-gar-936

WAY-GAR-936

Minocycline

Approved, Investigational

Phase 2

10118-90-8

5281021

Synonyms:

(2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(4S,4AS,5ar,12as)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE

10118-90-8

13614-98-7 (mono-hydrochloride)

4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide

4708-96-7

7-dimethylamino-6-Demethyl-6-deoxytetracycline

7-Dimethylamino-6-demethyl-6-deoxytetracycline

AC1NQXWM

Alti-Minocycline

Apo-Minocycline

Arestin

Bio-0062

Borymycin

BRN 3077644

C07225

C23H27N3O7

CHEBI:50694

CHEBI:529981

CHEMBL1434

CHEMBL259172

CID5281021

CL 59806

CRL-1605 & Minocycline

D05045

Dynacin

Gen-Minocycline

HMS2090D03

HSDB 3130

Klinomycin

Lactoferrin B & Minocycline

Lactoferrin H & Minocycline

LMPK07000002

LS-93850

MINO

Minociclina

Minociclina [INN-Spanish]

minociclinum

Minociclinum

Minocin

Minocin (Hydrochloride)

Minocline

Minocyclin

minocycline

Minocycline (USAN/INN)

Minocycline [USAN:BAN:INN]

Minocycline HCl

Minocycline Monohydrochloride

Minocyclinum

Minocyclinum [INN-Latin]

Minocyn

Minomycin

MIY

NCGC00178854-01

nchembio.559-comp1

Novo-Minocycline

NSC 141993

NSC141993

Solodyn

UNII-FYY3R43WGO

Vectrin

Vectrin (Hydrochloride)

Nitric Oxide

Approved

Phase 2

10102-43-9

145068

Synonyms:

(.)NO

(no)(.)

(NO)(.)

[no]

[NO]

10102-43-9

14332-28-6

295566_ALDRICH

51005-20-0

51005-21-1

53851-19-7

90452-29-2

AC1L1ADQ

AC1L3QHF

AC1Q6QZ0

AR-1K7463

Bioxyde d'azote

Bioxyde d'azote [French]

C00533

CCRIS 4319

CHEMBL1200689

CHEMBL1234765

CID145068

CID945

D00074

D009569

DB00435

EDRF

EINECS 233-271-0

Endogenous nitrate vasodilator

Endogenous Nitrate Vasodilator

Endothelium-derived nitric oxide

Endothelium-Derived Nitric Oxide

endothelium-derived relaxing factor

Endothelium-derived relaxing factor

HNO

HSDB 1246

INOmax

INOmax (TN)

LS-192158

LS-7547

MolPort-003-929-452

Mononitrogen monoxide

Monoxide, mononitrogen

Monoxide, Mononitrogen

Monoxide, nitrogen

Monoxide, Nitrogen

monoxido de nitrogeno

monoxido De nitrogeno

Monoxido de nitrogeno

monoxyde d'azote

Monoxyde d'azote

Nitrate vasodilator, endogenous

Nitrate Vasodilator, Endogenous

nitric oxide

Nitric oxide

Nitric oxide (JAN)

Nitric oxide 10% by volume or more

Nitric oxide trimer

Nitric oxide, compressed [UN1660] [Poison gas]

Nitric oxide, endothelium derived

Nitric Oxide, Endothelium Derived

Nitric oxide, endothelium-derived

Nitric Oxide, Endothelium-Derived

NITRIC-OXIDE

nitrogen monooxide

Nitrogen monooxide

nitrogen monoxide

Nitrogen monoxide

Nitrogen oxide

Nitrogen oxide (NO)

Nitrogen protoxide

nitrosyl

Nitrosyl

Nitrosyl hydride

Nitrosyl hydride ((NO)H)

Nitrosyl radical

Nitroxide radical

Nitroxyl

no(.)

NO(.)

OHM 11771

Oxide, nitric

Oxide, Nitric

óxido de nitrógeno(2)

oxido de nitrogeno(II)

oxido De nitrogeno(II)

Oxido de nitrogeno(ii)

oxido nitrico

oxido Nitrico

Oxido nitrico

oxidonitrogen(.)

oxoazanyl

oxyde azotique

Oxyde azotique

Oxyde nitrique

Oxyde nitrique [French]

RCRA waste no. P076

Stickmonoxyd

Stickmonoxyd [German]

Stickstoff(ii)-oxid

Stickstoff(II)-oxid

Stickstoffmonoxid

UN 1660

UN1660

UNII-31C4KY9ESH

Vasodilator, endogenous nitrate

Vasodilator, Endogenous Nitrate

Amikacin

Approved, Investigational, Vet_approved

Phase 2

37517-28-5

37768

Synonyms:

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide

(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxybutanamide

(2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide

108914-65-4

110660-81-6

110660-83-8

111319-93-8

1-N-(L(-)-g-amino-a-Hydroxybutyryl)kanamycin a

1-N-(L(-)-gamma-amino-alpha-Hydroxybutyryl)kanamycin a

1-N-(L(-)-gamma-Amino-alpha-hydroxybutyryl)kanamycin A

1-N-(L(-)-γ-amino-α-hydroxybutyryl)kanamycin a

1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A

37517-28-5

38859-32-4

A.M.K

AB00513828

AC1L1YE8

AC1Q5JTM

Amicacin

Amiglyde-V

amikacin

Amikacin

Amikacin & Tumor Necrosis Factor

Amikacin (USP)

Amikacin (USP/INN)

Amikacin [USAN:BAN:INN]

Amikacin base

Amikacin Base

Amikacin dihydrate

Amikacin Dihydrate

Amikacin sulfate

Amikacin Sulfate

AMIKACIN SULFATE

Amikacina

Amikacina [INN-Spanish]

Amikacina medical

Amikacina normon

amikacine

Amikacine

Amikacine [INN-French]

Amikacinum

Amikacinum [INN-Latin]

Amikafur

Amikalem

Amikason's

Amikavet

Amikayect

Amikin

Amikin (Disulfate)

Amiklin

Amukin

Antibiotic BB-K 8

ANTIBIOTIC BB-K8

Apothecon brand OF amikacin sulfate

Arikace

BB K 8

BB K8

BBK 8

BB-K 8

BBK8

BB-K8

Biclin

Biklin

BPBio1_000671

Briclin

Bristol myers squibb brand OF amikacin sulfate

Bristol-myers squibb brand OF amikacin sulfate

BSPBio_000609

C06820

C22H43N5O13

CHEBI:2637

CHEMBL177

CID37768

Collins brand OF amikacin sulfate

Cryopharma brand OF amikacin sulfate

D02543

DB00479

EINECS 253-538-5

Fustery brand OF amikacin sulfate

Galen brand OF amikacin sulfate

Gamikal

Grossmann brand OF amikacin sulfate

HSDB 3583

Kaminax

Kanbine

Lemery brand OF amikacin sulfate

LS-146896

Lukadin

Mead johnson brand OF amikacin sulfate

Medical brand OF amikacin sulfate

Medical, amikacina

Mikavir

MolPort-000-761-900

NCGC00093350-02

NCGC00093350-03

Norman brand OF amikacin sulfate

Normon, amikacina

NSC 177001

NSC177001

O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-[6-amino-6-deoxy-.alpha.-D-glucopyranosyl-(1->4)]-1-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine

O-3-amino-3-Deoxy-a-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-a-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine

O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine

O-3-amino-3-Deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine

O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-6))-N(sup 3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine

O-3-amino-3-Deoxy-α-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-α-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine

Oprad

Pisa brand OF amikacin sulfate

Prestwick3_000395

Rovi brand OF amikacin sulfate

Son's brand OF amikacin sulfate

STK039706

Sulfate, amikacin

UNII-84319SGC3C

Yectamid

Molgramostim

Investigational

Phase 2

99283-10-0

Anti-Infective Agents

Phase 2

Anti-Bacterial Agents

Phase 2

Vasodilator Agents

Phase 2

Endothelium-Dependent Relaxing Factors

Phase 2

Anti-Asthmatic Agents

Phase 2

Peripheral Nervous System Agents

Phase 2

Antioxidants

Phase 2

Protective Agents

Phase 2

Respiratory System Agents

Phase 2

Neurotransmitter Agents

Phase 2

Free Radical Scavengers

Phase 2

Bronchodilator Agents

Phase 2

Autonomic Agents

Phase 2

Antibiotics, Antitubercular

Phase 2

Pharmaceutical Solutions

Phase 2

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Azithromycin in the Treatment of M. Avium Complex Lung Disease	Completed	NCT00599079	Phase 4	Azithromycin
2	Tigecycline for Treatment of Rapidly Growing Mycobacteria	Completed	NCT00600600	Phase 2	Tigecycline
3	Inhaled Nitric Oxide for Patients With MABSC	Recruiting	NCT03208764	Phase 2	Nitric Oxide
4	Liposomal Amikacin for Inhalation (LAI) in the Treatment of Mycobacterium Abscessus Lung Disease	Active, not recruiting	NCT03038178	Phase 2	LAI plus multi-drug regimen
5	Trial of Inhaled Molgramostim in CF Subjects With NTM Infection	Not yet recruiting	NCT03597347	Phase 2	Molgramostim nebulizer solution
6	Inhaled Amikacin Treatment for Nontuberculous Mycobacterial Lung Disease	Withdrawn	NCT01528930	Phase 2	Amikacin
7	The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease	Unknown status	NCT02005094
8	The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis	Unknown status	NCT01354912
9	Genome-Wide Association Study in Patients With Nontuberculous Mycobacterial Lung Disease	Recruiting	NCT02832843
10	The Italian REgistry of Pulmonary Non-tuberculous mycobactEria	Recruiting	NCT03339063

Search NIH Clinical Center for Mycobacterium Abscessus

Sources

Genetic Tests for Mycobacterium Abscessus

Sources

Anatomical Context for Mycobacterium Abscessus

MalaCards organs/tissues related to Mycobacterium Abscessus:

⁴¹

Lung, Skin, Testes, Colon, Prostate, Liver, Bone

Sources

Publications for Mycobacterium Abscessus

Articles related to Mycobacterium Abscessus:

(show top 50) (show all 694)

#	Title	Authors	Year
1	Mycobacterium abscessus Infections in Children: A Review of Current Literature. ( 29897511 )	Lamb G.S....Starke J.R.	2018
2	Determination of MIC Distribution and Mechanisms of Decreased Susceptibility to Bedaquiline among Clinical Isolates of Mycobacterium abscessus. ( 29712658 )	Li B....Chu H.	2018
3	Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus. ( 29913527 )	Ramis I.B....da Silva P.E.A.	2018
4	Mycobacterium abscessus Left Ventricle Assist Device Driveline Infections: An Emerging Pathogen? ( 29896814 )	Nunez Breton J.D....Chaparro S.V.	2018
5	<i>Mycobacterium abscessus</i> complex: Natural history and treatment outcomes at a tertiary adult cystic fibrosis center. ( 29900884 )	Tippett E....Spelman D.	2018
6	<i>Mycobacterium abscessus</i> subsp. <i>massiliense mycma_0076</i> and <i>mycma_0077</i> Genes Code for Ferritins That Are Modulated by Iron Concentration. ( 29910777 )	Oliveira F.M....Kipnis A.	2018
7	<i>Mycobacterium abscessus</i> Complex Infections: A Retrospective Cohort Study. ( 29450214 )	Sfeir M....Abbo L.M.	2018
8	Clinical aspects in patients with pulmonary infection caused by mycobacteria of the Mycobacterium abscessus complex, in the Brazilian Amazon. ( 29791556 )	Monteiro J.T.C....Dalcolmo M.P.	2018
9	<i>Mycobacterium abscessus</i> Smooth And Rough Morpohotypes Form Antimicrobial-Tolerant Biofilm Phenotypes But Are Killed by Acetic Acid. ( 29311080 )	Clary G....Hall-Stoodley L.	2018
10	Glycopeptidolipids, a Double-Edged Sword of the <i>Mycobacterium abscessus</i> Complex. ( 29922253 )	GutiAcrrez A.V....Kremer L.	2018
11	Complete Genome Sequence of a Type Strain of<i>Mycobacterium abscessus</i>subsp.<i>bolletii</i>, a Member of the<i>Mycobacterium abscessus</i>Complex. ( 29437099 )	Yoshida M....Hoshino Y.	2018
12	Rifabutin acts in synergy and is bactericidal with frontline <i>Mycobacterium abscessus</i> antibiotics clarithromycin and tigecycline, suggesting a potent treatment combination. ( 29760147 )	Pryjma M....Thompson C.J.	2018
13	Antimicrobial effect of dimethyl sulfoxide and <i>N, N</i>-Dimethylformamide on <i>Mycobacterium abscessus</i>: Implications for antimicrobial susceptibility testing. ( 29900888 )	Kirkwood Z.I....Moore J.E.	2018
14	A Successful Aggressive Surgical and Medical approach to Pulmonary Artery Obstruction due to Mycobacterium abscessus Infection post Lung Transplantation. ( 29359876 )	Kotecha S....McGiffin D.	2018
15	<i>In vitro</i> and intracellular activity of imipenem combined to rifabutin and avibactam against <i>Mycobacterium abscessus</i>. ( 29866869 )	Le Run E....Mainardi J.L.	2018
16	Identification of genes required for<i>Mycobacterium abscessus</i>growth in vivo with a prominent role of the ESX-4 locus. ( 29343644 )	Laencina L....Girard-Misguich F.	2018
17	Association between sequevar and antibiotic treatment outcome in patients with Mycobacterium abscessus complex infections in Japan. ( 29227218 )	Yoshida S....Suzuki K.	2018
18	In Vitro Efficacy of Free and Nanoparticle Formulations of Gallium(III) meso-Tetraphenylporphyrine against Mycobacterium avium and Mycobacterium abscessus and Gallium Biodistribution in Mice. ( 29421865 )	Choi S.R....Narayanasamy P.	2018
19	Cutaneous infection with Mycobacterium abscessus. ( 29974168 )		2018
20	Mycobacterium abscessus and massiliense lung infection during macrolide treatment for bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation. ( 28988958 )		2018
21	Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for rapid identification of<i>Mycobacterium abscessus</i>. ( 29386727 )		2018
22	Disseminated <i>Mycobacterium abscessus</i> infection with spondylodiscitis of thoracic spine. ( 29942485 )		2018
23	Teicoplanin - Tigecycline Combination Shows Synergy Against <i>Mycobacterium abscessus</i>. ( 29867841 )		2018
24	Pathogen Box screening for hit identification against Mycobacterium abscessus. ( 29698397 )		2018
25	Pulmonary alveolar proteinosis and <i>Mycobacterium abscessus</i> lung infection related to ruxolitinib after allogeneic stem cell transplantation. ( 29650554 )		2018
26	Inhaled Granulocyte-Macrophage Colony Stimulating Factor for<b> <i>Mycobacterium Abscessus</i> </b>in Cystic Fibrosis. ( 29419443 )		2018
27	Mycobacterium abscessus infections in lung transplant recipients: 15-year experience from a single institution. ( 29359872 )		2018
28	Chronic Otitis Media Caused by Mycobacterium abscessus spp. massiliense Treated by Tigecycline in a 10 year-old-child. ( 29966711 )		2018
29	In vitro activity of tedizolid against the Mycobacterium abscessus complex. ( 29217419 )		2018
30	Anomalies in T Cell Function Are Associated With Individuals at Risk of <i>Mycobacterium abscessus</i> Complex Infection. ( 29942313 )		2018
31	First United States Outbreak of Mycobacterium abscessus Hand and Foot Disease Among Children Associated With a Wading Pool. ( 29850835 )		2018
32	Mutations in <i>gyrA</i> and <i>gyrB</i> in Moxifloxacin-Resistant <i>Mycobacterium avium</i> Complex and <i>Mycobacterium abscessus</i> Complex Clinical Isolates. ( 29914959 )		2018
33	Pulmonary Mycobacterium abscessus Infection with Reactive AA Amyloidosis: A Case Report and Brief Review of the Literature. ( 30333399 )	Torii R...Yatera K	2018
34	Microscopic polyangiitis secondary to Mycobacterium abscessus in a patient with bronchiectasis: a case report. ( 30453935 )	Addy C...Downey DG	2018
35	Mycobacterium abscessus Infection During Ustekinumab Treatment in Crohn's Disease: A Case Report and Review of the Literature. ( 30169620 )	Shim HH...Ling KL	2018
36	The importance of early diagnosis of Mycobacterium abscessus complex in patients with cystic fibrosis. ( 30456869 )	Ravnholt C...Qvist T	2018
37	Antimycobacterial activity of nonantibiotics associated with the polypharmacy of cystic fibrosis (CF) against mycobacterium abscessus. ( 30531035 )	Kirkwood ZI...Moore JE	2018
38	Interaction of South Asian spices with conventional antibiotics: Implications for antimicrobial resistance for Mycobacterium abscessus and cystic fibrosis. ( 30198506 )	Moore RE...Moore JE	2018
39	Antimycobacterial activity of veterinary antibiotics (Apramycin and Framycetin) against Mycobacterium abscessus: Implication for patients with cystic fibrosis. ( 30198508 )	Moore JE...Millar BC	2018
40	In vitro activity of seven hospital biocides against Mycobacterium abscessus: Implications for patients with cystic fibrosis. ( 29516885 )	Caskey S...Rendall JC	2018
41	Non-Tuberculous Mycobacteria multispecies biofilms in cystic fibrosis: development of an in vitro Mycobacterium abscessus and Pseudomonas aeruginosa dual species biofilm model. ( 29555180 )	Rodr?guez-Sevilla G...P?rez-Jorge C	2018
42	Mycobacterium abscessus infection in a boy with X-linked anhidrotic ectodermal dysplasia, immunodeficiency. ( 30243918 )	Yu HH...Chiang BL	2018
43	The Clarithromycin Susceptibility Genotype Affects the Treatment Outcome of Patients with Mycobacterium abscessus Lung Disease. ( 29483126 )	Guo Q...Yu F	2018
44	Mycobacterium abscessus subsp. abscessus Lung Disease: Drug Susceptibility Testing in Sputum Culture Negative Conversion. ( 29516889 )	Kobayashi T...Suzuki K	2018
45	Survival of pathogenic Mycobacterium abscessus subsp. massiliense in Acanthamoeba castellanii. ( 29056478 )	da Silva JL...Olivier KN	2018
46	Molecular Mechanisms of Intrinsic Streptomycin Resistance in Mycobacterium abscessus. ( 29061744 )	Dal Molin M...Sander P	2018
47	In Vitro Evaluation of Povidone-Iodine and Chlorhexidine against Outbreak and Nonoutbreak Strains of Mycobacterium abscessus Using Standard Quantitative Suspension and Carrier Testing. ( 29061748 )	Cheng A...Chang SC	2018
48	In vitro activity between linezolid and other antimicrobial agents against Mycobacterium abscessus complex. ( 29089153 )	Zhang Z...Pang Y	2018
49	Mycobacterium abscessus, a taxonomic puzzle. ( 29139343 )	Tortoli E...Cirillo DM	2018
50	Activity of Rifabutin and Hemi-synthetic Derivatives Against Mycobacterium abscessus. ( 29205119 )	Ramis IB...da Silva PEA	2018

Sources

Genes for Mycobacterium Abscessus

Genes related to Mycobacterium Abscessus (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TLR2	Toll Like Receptor 2	Protein Coding	17.53	GeneCards inferred via : Publications (show sections)
2	CFTR	Cystic Fibrosis Transmembrane Conductance Regulator	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
3	CLEC7A	C-Type Lectin Domain Containing 7A	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
4	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
5	HMOX1	Heme Oxygenase 1	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
6	IFNGR2	Interferon Gamma Receptor 2	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
7	SQSTM1	Sequestosome 1	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
8	SYK	Spleen Associated Tyrosine Kinase	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
9	NLRP3	NLR Family Pyrin Domain Containing 3	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
10	SERPINA1	Serpin Family A Member 1	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
11	TNF	Tumor Necrosis Factor	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
12	TLR1	Toll Like Receptor 1	Protein Coding	16.98	GeneCards inferred via : Publications (show sections)
13	MSRA	Methionine Sulfoxide Reductase A	Protein Coding	6.98	GeneCards inferred via : Publications (show sections)

Sources

Variations for Mycobacterium Abscessus

Sources

Expression for Mycobacterium Abscessus

Search GEO for disease gene expression data for Mycobacterium Abscessus.

Sources

Pathways for Mycobacterium Abscessus

Pathways related to Mycobacterium Abscessus according to GeneCards Suite gene sharing:

(show all 31)

#	Super pathways	Score	Top Affiliating Genes
1	Innate Immune System ⁶⁶ Show member pathways Immune System ⁶⁶ Neutrophil degranulation ⁶⁶	13.74	CLEC7A CXCL8 HMOX1 IFNGR2 NLRP3 SERPINA1
2	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	13.21	CXCL8 HMOX1 IFNGR2 SQSTM1 SYK TNF
3	Influenza A ³⁷ Show member pathways Herpes simplex infection ³⁷ Measles ³⁷	12.66	CXCL8 IFNGR2 NLRP3 TLR2 TNF
4	Toll-like Receptor Signaling Pathway ³⁷ ¹ Show member pathways Chagas disease (American trypanosomiasis) ³⁷ NOD-like receptor signaling pathway ³⁷ NOD-like Receptor Signaling Pathways ⁶⁵ Regulation of toll-like receptor signaling pathway ¹	12.61	CXCL8 IFNGR2 NLRP3 SQSTM1 SYK TLR1
5	NF-kappaB Signaling ⁴	12.39	HMOX1 SYK TLR1 TLR2 TNF
6	IL-17 Family Signaling Pathways ⁶⁵ Show member pathways IL17 signaling pathway ¹ IL-17 signaling pathway ³⁷ Interleukin-17 signaling ⁶⁶ Mucin expression in CF via IL-6, IL-17 signaling pathways ²²	12.22	CFTR CXCL8 TLR2 TNF
7	Toxoplasmosis ³⁷ Show member pathways Leishmaniasis ³⁷	12.1	IFNGR2 TLR2 TNF
8	C-type lectin receptor signaling pathway ³⁷ Show member pathways Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways ⁶⁵	12.09	CLEC7A NLRP3 SYK TNF
9	Necroptosis ³⁷ Show member pathways Nanoparticle triggered regulated necrosis ¹	12.08	IFNGR2 NLRP3 SQSTM1 TNF
10	Colorectal Cancer Metastasis ⁶⁴	12.04	IFNGR2 TLR1 TLR2 TNF
11	Diseases associated with the TLR signaling cascade ⁶⁶ Show member pathways Diseases of Immune System ⁶⁶ Interleukin-1 Induced Activation of NF-kappa-B ¹ IRAK1 recruits IKK complex ⁶⁶ IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation ⁶⁶ IRAK4 deficiency (TLR2/4) ⁶⁶ IRAK4 deficiency (TLR5) ⁶⁶ MyD88 deficiency (TLR2/4) ⁶⁶ MyD88 deficiency (TLR5) ⁶⁶ Simplified Depiction of MYD88 Distinct Input-Output Pathway ¹ TLR4 Signaling and Tolerance ¹ Toll-like Receptor Signaling ¹	12.04	CXCL8 SQSTM1 TLR1 TLR2 TNF
12	NRF2 pathway ¹	11.98	HMOX1 SERPINA1 SQSTM1
13	Fluid shear stress and atherosclerosis ³⁷	11.96	HMOX1 SQSTM1 TNF
14	Th1 Differentiation Pathway ⁶⁵ Show member pathways IL27-mediated signaling events ¹ Th17 Differentiation Pathway ⁶⁵	11.93	IFNGR2 TLR1 TLR2 TNF
15	Microglia Activation During Neuroinflammation: Overview ⁶⁵ Show member pathways Microglia Activation During Neuroinflammation: Microglia Activation ⁶⁵	11.91	TLR1 TLR2 TNF
16	Osteoclast differentiation ³⁷	11.9	IFNGR2 SQSTM1 SYK TNF
17	IL-1 Family Signaling Pathways ⁶⁵ Show member pathways Immune response IL-1 signaling pathway ²² Mucin expression in CF via TLRs, EGFR signaling pathways ²²	11.9	CFTR CXCL8 HMOX1 TLR2 TNF
18	Interleukin-4 and 13 signaling ⁶⁶	11.86	CXCL8 HMOX1 TNF
19	Amoebiasis ³⁷	11.78	CXCL8 TLR2 TNF
20	NF-kappa B signaling pathway ³⁷	11.77	CXCL8 SYK TNF
21	Rheumatoid arthritis ³⁷	11.74	CXCL8 TLR2 TNF
22	Phagocytosis of Microbes ⁶⁴	11.7	CLEC7A TLR1 TLR2
23	Tuberculosis ³⁷	11.69	CLEC7A IFNGR2 SYK TLR1 TLR2 TNF
24	Pertussis ³⁷	11.65	CXCL8 NLRP3 TNF
25	Legionellosis ³⁷	11.48	CXCL8 TLR2 TNF
26	Malaria ³⁷	11.42	CXCL8 TLR2 TNF
27	Lung fibrosis ¹	11.42	CXCL8 HMOX1 SERPINA1 TNF
28	Bacterial infections in CF airways ²² Show member pathways IL-1 beta-dependent CFTR expression ²² Immune response Bacterial infections in normal airways ²² Immune response TLR signaling pathways ²²	11.32	CFTR CXCL8 IFNGR2 TLR1 TLR2 TNF
29	EBV LMP1 signaling ¹	11.03	CXCL8 TNF
30	IL1 and megakaryocytes in obesity ¹	11.03	NLRP3 TLR1 TLR2
31	Overview of nanoparticle effects ¹	10.89	CXCL8 HMOX1 TNF

Sources

GO Terms for Mycobacterium Abscessus

Cellular components related to Mycobacterium Abscessus according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	endoplasmic reticulum	GO:0005783	9.43	CFTR HMOX1 IFNGR2 NLRP3 SERPINA1 SQSTM1
2	Toll-like receptor 1-Toll-like receptor 2 protein complex	GO:0035354	8.62	TLR1 TLR2

Biological processes related to Mycobacterium Abscessus according to GeneCards Suite gene sharing:

(show all 29)

#	Name	GO ID	Score	Top Affiliating Genes
1	immune response	GO:0006955	9.94	CXCL8 TLR1 TLR2 TNF
2	intracellular signal transduction	GO:0035556	9.91	CXCL8 HMOX1 SQSTM1 SYK
3	innate immune response	GO:0045087	9.83	CLEC7A NLRP3 SYK TLR1 TLR2
4	cellular response to lipopolysaccharide	GO:0071222	9.8	CXCL8 NLRP3 TNF
5	positive regulation of NF-kappaB transcription factor activity	GO:0051092	9.78	NLRP3 TLR2 TNF
6	cytokine-mediated signaling pathway	GO:0019221	9.78	CXCL8 HMOX1 IFNGR2 TNF
7	defense response to Gram-positive bacterium	GO:0050830	9.67	NLRP3 TLR2 TNF
8	regulation of tumor necrosis factor-mediated signaling pathway	GO:0010803	9.64	SYK TNF
9	positive regulation of cytokine secretion	GO:0050715	9.63	SYK TNF
10	positive regulation of interleukin-8 production	GO:0032757	9.63	TLR2 TNF
11	regulation of DNA-binding transcription factor activity	GO:0051090	9.62	HMOX1 SYK
12	positive regulation of interleukin-4 production	GO:0032753	9.6	NLRP3 SYK
13	positive regulation of chemokine production	GO:0032722	9.59	TLR2 TNF
14	microglial cell activation	GO:0001774	9.58	TLR2 TNF
15	embryonic digestive tract development	GO:0048566	9.58	CXCL8 TNF
16	regulation of I-kappaB kinase/NF-kappaB signaling	GO:0043122	9.57	SQSTM1 TNF
17	negative regulation of growth of symbiont in host	GO:0044130	9.56	SQSTM1 TNF
18	defense response	GO:0006952	9.56	CXCL8 NLRP3 TLR1 TNF
19	positive regulation of interleukin-8 secretion	GO:2000484	9.55	TLR1 TLR2
20	regulation of cytokine secretion	GO:0050707	9.54	TLR1 TLR2
21	cell activation	GO:0001775	9.52	TLR1 TLR2
22	response to molecule of bacterial origin	GO:0002237	9.51	CXCL8 TLR2
23	positive regulation of chemokine biosynthetic process	GO:0045080	9.46	HMOX1 TNF
24	immune system process	GO:0002376	9.43	CLEC7A NLRP3 SQSTM1 SYK TLR1 TLR2
25	cellular response to triacyl bacterial lipopeptide	GO:0071727	9.4	TLR1 TLR2
26	cytokine secretion involved in immune response	GO:0002374	9.37	NLRP3 TLR2
27	toll-like receptor TLR1:TLR2 signaling pathway	GO:0038123	9.32	TLR1 TLR2
28	detection of triacyl bacterial lipopeptide	GO:0042495	9.16	TLR1 TLR2
29	inflammatory response	GO:0006954	9.1	CLEC7A CXCL8 NLRP3 TLR1 TLR2 TNF

Molecular functions related to Mycobacterium Abscessus according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	identical protein binding	GO:0042802	9.43	NLRP3 SERPINA1 SQSTM1 TLR1 TLR2 TNF
2	peptidoglycan binding	GO:0042834	9.32	NLRP3 TLR2
3	signaling pattern recognition receptor activity	GO:0008329	9.26	CLEC7A TLR2
4	lipopeptide binding	GO:0071723	9.16	TLR1 TLR2
5	Toll-like receptor binding	GO:0035325	8.62	SYK TLR2

Sources

Sources for Mycobacterium Abscessus

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

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¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

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³⁰ HGMD

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³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

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⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia