MCID: MYC015
MIFTS: 32

Mycobacterium Fortuitum

Categories: Bone diseases, Immune diseases, Rare diseases

Aliases & Classifications for Mycobacterium Fortuitum

MalaCards integrated aliases for Mycobacterium Fortuitum:

Name: Mycobacterium Fortuitum 52
Mycobacterium Fortuitum Infection 52
M. Fortuitum 52

Classifications:



Summaries for Mycobacterium Fortuitum

NIH Rare Diseases : 52 Mycobacterium fortuitum is a bacteria that can cause infections of many areas of the body including the skin, lymph nodes , and joints. It belongs to a group of bacteria, known as nontuberculous mycobacterium, as it is different from the Mycobacterium that causes tuberculosis . It can be found in natural and processed water, sewage, and dirt. Healthy people usually do not get Mycobacterium fortuitum infections; however, they may occur after surgery, in people with an impaired immune system , or after exposure to a contaminated medical device (such as an endoscope). It is uncommon for this condition to cause lung disease, but Mycobacterium fortuitum infection can lead to skin disease, osteomyelitis (inflammation of the bone), joint infections, and eye disease . The signs and symptoms of infection differ depending on the infection site. Treatment also depends on the site of the infection, but usually includes prolonged use of antibiotics .

MalaCards based summary : Mycobacterium Fortuitum, also known as mycobacterium fortuitum infection, is related to meningitis and endocarditis. An important gene associated with Mycobacterium Fortuitum is LACTB (Lactamase Beta), and among its related pathways/superpathways are Pathways in cancer and Bacterial infections in CF airways. The drugs interferons and Antiviral Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and testes.

Wikipedia : 74 Mycobacterium fortuitum is a nontuberculous species of the phylum Actinobacteria (Gram-positive bacteria... more...

Related Diseases for Mycobacterium Fortuitum

Diseases related to Mycobacterium Fortuitum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 195)
# Related Disease Score Top Affiliating Genes
1 meningitis 30.5 LACTB CXCL8
2 endocarditis 30.4 LACTB HSPD1 CXCL8
3 osteomyelitis 30.4 IFNGR1 CXCL8
4 pulmonary tuberculosis 30.1 IL12RB1 IFNGR1
5 leprosy 3 30.0 HSPD1 CXCL8
6 pneumonia 30.0 LACTB HSPD1 CXCL8
7 bacterial meningitis 29.9 LACTB CXCL8
8 bacterial pneumonia 29.8 LACTB CXCL8
9 lymphadenitis 29.7 IL12RB1 IFNGR1 CXCL8
10 bronchitis 29.6 LACTB CXCL8
11 otitis media 29.6 LACTB CXCL8
12 nocardiosis 29.5 LACTB IL12RB1 HSPD1
13 lepromatous leprosy 29.3 IL12RB1 IFNGR1 HSPD1
14 immunodeficiency 28 11.4
15 mycobacterium chelonae 10.8
16 peritonitis 10.6
17 lung disease 10.6
18 mycobacterium abscessus 10.6
19 keratitis, hereditary 10.5
20 achalasia 10.4
21 mycobacterium kansasii 10.4
22 pleural empyema 10.4
23 infective endocarditis 10.4
24 mastitis 10.4
25 cervical adenitis 10.4
26 immune deficiency disease 10.3
27 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.3
28 breast abscess 10.3
29 acute cystitis 10.3
30 corneal ulcer 10.3
31 lupus erythematosus 10.3
32 bronchiectasis 10.3
33 47,xyy 10.3
34 systemic lupus erythematosus 10.2
35 human immunodeficiency virus type 1 10.2
36 aspiration pneumonia 10.2
37 lung abscess 10.2
38 mastoiditis 10.2
39 panniculitis 10.2
40 bone inflammation disease 10.2
41 cellulitis 10.2
42 acquired immunodeficiency syndrome 10.2
43 septic arthritis 10.2
44 arthritis 10.2
45 mycobacterium marinum 10.2
46 prosthetic joint infection 10.2
47 leukemia, acute lymphoblastic 10.2
48 gastric cancer 10.2
49 pleurisy 10.2
50 respiratory failure 10.2

Graphical network of the top 20 diseases related to Mycobacterium Fortuitum:



Diseases related to Mycobacterium Fortuitum

Symptoms & Phenotypes for Mycobacterium Fortuitum

Drugs & Therapeutics for Mycobacterium Fortuitum

Drugs for Mycobacterium Fortuitum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 interferons Phase 1
2 Antiviral Agents Phase 1
3 Interferon-gamma Phase 1
4 Anti-Infective Agents Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Study of Adjuvant Cytokine Therapy in Pulmonary Mycobacterium Avium Complex and Other Pulmonary Nontuberculous Mycobacterial Infections Completed NCT00111397 Phase 1 Interferon Gamma, GM-CSF
2 The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis Unknown status NCT01354912
3 Natural History, Genetics, Phenotype and Treatment of Mycobacterial Infections Recruiting NCT00018044

Search NIH Clinical Center for Mycobacterium Fortuitum

Genetic Tests for Mycobacterium Fortuitum

Anatomical Context for Mycobacterium Fortuitum

MalaCards organs/tissues related to Mycobacterium Fortuitum:

40
Skin, Lung, Testes, Bone, Lymph Node, Eye, Breast

Publications for Mycobacterium Fortuitum

Articles related to Mycobacterium Fortuitum:

(show top 50) (show all 1305)
# Title Authors PMID Year
1
Clinical and laboratory aspects of the diagnosis and management of cutaneous and subcutaneous infections caused by rapidly growing mycobacteria. 52 61
23139042 2013
2
Dissecting microbial community structure in sewage treatment plant for pathogens' detection using metagenomic sequencing technology. 61
31848653 2020
3
Successful bedaquiline-containing antimycobacterial treatment in post-traumatic skin and soft-tissue infection by Mycobacterium fortuitum complex: a case report. 61
32448204 2020
4
Nontuberculous mycobacterial infections in left ventricular assist device patients. 61
32253770 2020
5
Identification of mycobacteria species by molecular methods. 61
31863568 2020
6
Odontogenic cutaneous sinus tracts due to infection with nontuberculous mycobacteria: a report of three cases. 61
32316920 2020
7
Drug susceptibility patterns of rapidly growing mycobacteria isolated from skin and soft tissue infections in Venezuela. 61
31741101 2020
8
A cross-sectional epidemiological investigation of nontuberculous mycobacteria of public health importance in slaughter camels in Samburu County, Kenya. 61
31448381 2020
9
Fiber optic interferometric immunosensor based on polydimethilsiloxane (PDMS) and bioactive lipids. 61
32206412 2020
10
Exogenous lipoid pneumonia in children: A systematic review. 61
30962152 2020
11
Inactivation of milk-borne pathogens by blue light exposure. 61
31759598 2020
12
Clinical-epidemiological profile and factors related to the mortality of patients with nontuberculous mycobacteria isolated at a reference hospital in Ceará, Northeastern Brazil. 61
32474494 2020
13
Atypical Laryngeal Infections: Localized Lesions from Unusual Organisms May Simulate Malignancy. 61
31522522 2020
14
Nail Salon a Potential Source of a Rare Mycobacterium Fortuitum Infection In Proximal Tibia Megaprosthesis? A Case Report. 61
32566452 2020
15
Cas12a/Guide RNA-Based Platform for Rapid and Accurate Identification of Major Mycobacterium Species. 61
31723010 2020
16
An overview of pulmonary infections due to rapidly growing mycobacteria in South Asia and impressions from a subtropical region. 61
32474491 2020
17
A Current Microbiological Picture of Mycobacterium Isolates from Istanbul, Turkey. 61
32468806 2020
18
Incidence, Clinical Manifestation, Treatment Outcome, and Drug Susceptibility Pattern of Nontuberculous Mycobacteria in HIV Patients in Tehran, Iran. 61
32116435 2020
19
Inhibition of Mycobacterium abscessus, M. chelonae, and M. fortuitum biofilms by Methylobacterium sp. 61
31481764 2020
20
Random insertion transposon mutagenesis of Mycobacterium fortuitum identified mutant defective in biofilm formation. 61
31727369 2020
21
Minimum inhibitory concentration changes in relapsed left ventricular assist device driveline infections. 61
31964206 2020
22
Pseudo-outbreak of Mycobacterium fortuitum in a hospital bronchoscopy unit. 61
31882175 2019
23
INNO-LiPA DNA line probe assay misidentification of M. smegmatis as Mycobacterium fortuitum complex. 61
31358343 2019
24
Profile of patients with pulmonary non-tuberculous mycobacterial disease mimicking pulmonary tuberculosis. 61
31813432 2019
25
The Chemical composition and anti-mycobacterial activities of Trachyspermum copticum and Pelargonium graveolens essential oils. 61
31657682 2019
26
In vivo infection and In vitro stress survival studies of acid susceptible mutant of Mycobacterium fortuitum. 61
31793511 2019
27
Diagnosis and management of postlaparotomy wound infection caused by Mycobacterium fortuitum. 61
31793513 2019
28
Culture positivity of smear negative pulmonary and extrapulmonary tuberculosis- A study from North Kerala, India. 61
31681664 2019
29
Hypercalcaemia secondary to disseminated Mycobacterium abscessus and Mycobacterium fortuitum. 61
31497789 2019
30
Failure among Patients with Non-Tuberculous Mycobacterial Infections in Skin, Soft Tissue, and Musculoskeletal System in Southern Taiwan, 2012-2015. 61
31066636 2019
31
Outbreak of Tattoo-associated Nontuberculous Mycobacterial Skin Infections. 61
30452604 2019
32
A case of pleural effusion caused by Mycobacterium fortuitum and Mycobacterium mageritense coinfection. 61
31416441 2019
33
Mycobacterium fortuitum infection of a hemodialysis catheter in a pediatric patient. 61
30746835 2019
34
Cardiovascular implantable electronic device infection with rapidly growing mycobacteria. 61
31384195 2019
35
Non-pigmented rapidly growing mycobacteria smooth and rough colony phenotypes pathogenicity evaluated using in vitro and experimental models. 61
31583400 2019
36
[Species diversity of non-tuberculous mycobacteria isolated from aquatic environments of General Pico city, Province of La Pampa (Argentina)]. 61
30579706 2019
37
Preliminary evaluation of the positively and negatively charge effects of tetra-substituted porphyrins on photoinactivation of rapidly growing mycobacteria. 61
31378267 2019
38
Species Distribution and Macrolide Susceptibility of Mycobacterium fortuitum Complex Clinical Isolates. 61
30885902 2019
39
Repurposing disulfiram to target infections caused by non-tuberculous mycobacteria. 61
30753528 2019
40
In Vitro Activities of Omadacycline against Rapidly Growing Mycobacteria. 61
30858221 2019
41
Outbreak of Nontuberculous Mycobacteria Joint Prosthesis Infections, Oregon, USA, 2010-2016. 61
31002056 2019
42
Mycobacterium fortuitum Meningitis: Approach to Lumboperitoneal Shunt Infection. 61
30943540 2019
43
Multicenter evaluation of the biochip assay for rapid detection of mycobacterial isolates in smear-positive specimens. 61
30685589 2019
44
Mycobacterium fortuitum as a cause of acute CNS infection in an immune-competent girl undergoing repeated VP shunt surgeries. 61
30992281 2019
45
Ribosomal maturation factor (RimP) is essential for survival of nontuberculous mycobacteria Mycobacterium fortuitum under in vitro acidic stress conditions. 61
30863706 2019
46
Surgical wound infection following open humeral fracture caused by Mycobacterium houstonense: a case report. 61
31014284 2019
47
Study of characteristics of mycobacteriophage - A novel tool to treat Mycobacterium spp. 61
31210161 2019
48
Cardiac resynchronization therapy-defibrillator pocket infection caused by Mycobacterium fortuitum: a case report and review of the literature. 61
30836955 2019
49
Species Typing of Nontuberculous Mycobacteria by Use of Deoxyribozyme Sensors. 61
30523201 2019
50
Antimicrobial susceptibility testing of Mycobacteroides (Mycobacterium) abscessus complex, Mycolicibacterium (Mycobacterium) fortuitum, and Mycobacteroides (Mycobacterium) chelonae. 61
30447882 2019

Variations for Mycobacterium Fortuitum

Expression for Mycobacterium Fortuitum

Search GEO for disease gene expression data for Mycobacterium Fortuitum.

Pathways for Mycobacterium Fortuitum

Pathways related to Mycobacterium Fortuitum according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.86 IL12RB1 IFNGR1 CXCL8
2
Show member pathways
11.59 IFNGR1 CXCL8
3 11.53 HSPD1 CXCL8
4
Show member pathways
11.28 IL12RB1 IFNGR1
5
Show member pathways
11.12 IL12RB1 CXCL8
6 10.38 HSPD1 CXCL8

GO Terms for Mycobacterium Fortuitum

Biological processes related to Mycobacterium Fortuitum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of interferon-gamma production GO:0032729 9.16 IL12RB1 HSPD1
2 cytokine-mediated signaling pathway GO:0019221 9.13 IL12RB1 IFNGR1 CXCL8
3 positive regulation of tumor necrosis factor secretion GO:1904469 8.62 IFNGR1 HSPD1

Molecular functions related to Mycobacterium Fortuitum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine receptor activity GO:0004896 8.96 IL12RB1 IFNGR1
2 cytokine binding GO:0019955 8.62 IL12RB1 IFNGR1

Sources for Mycobacterium Fortuitum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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