MCID: MYC015
MIFTS: 33

Mycobacterium Fortuitum

Categories: Bone diseases, Immune diseases, Rare diseases

Aliases & Classifications for Mycobacterium Fortuitum

MalaCards integrated aliases for Mycobacterium Fortuitum:

Name: Mycobacterium Fortuitum 53
Mycobacterium Fortuitum Infection 53
M. Fortuitum 53

Classifications:



Summaries for Mycobacterium Fortuitum

NIH Rare Diseases : 53 Mycobacterium fortuitum is a bacteria that can cause infections of many areas of the body including the skin, lymph nodes, and joints. It belongs to a group of bacteria, known as nontuberculous mycobacterium, as it is different from the Mycobacterium that causes tuberculosis. It can be found in natural and processed water, sewage, and dirt. Healthy people usually do not get Mycobacterium fortuitum infections; however, they may occur after surgery, in people with an impaired immune system, or after exposure to a contaminated medical device (such as an endoscope). It is uncommon for this condition to cause lung disease, but Mycobacterium fortuitum infection can lead to skin disease, osteomyelitis (inflammation of the bone), joint infections, and eye disease. The signs and symptoms of infection differ depending on the infection site. Treatment also depends on the site of the infection, but usually includes prolonged use of antibiotics.

MalaCards based summary : Mycobacterium Fortuitum, also known as mycobacterium fortuitum infection, is related to pneumonia and endocarditis. An important gene associated with Mycobacterium Fortuitum is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), and among its related pathways/superpathways are Pathways in cancer and Tuberculosis. The drugs interferons and Antiviral Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and testes.

Wikipedia : 75 Mycobacterium fortuitum is a nontuberculous species of the phylum Actinobacteria (Gram-positive bacteria... more...

Related Diseases for Mycobacterium Fortuitum

Diseases related to Mycobacterium Fortuitum via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 171)
# Related Disease Score Top Affiliating Genes
1 pneumonia 30.6 LACTB CXCL8
2 endocarditis 30.3 LACTB HSPD1 CXCL8
3 osteomyelitis 30.3 IFNGR1 CXCL8
4 meningitis 30.2 LACTB CXCL8
5 nocardiosis 30.1 IL12RB1 HSPD1
6 bacterial pneumonia 30.0 LACTB CXCL8
7 immune deficiency disease 30.0 IL12RB1 IFNGR1
8 otitis media 29.9 LACTB CXCL8
9 lepromatous leprosy 29.8 IL12RB1 IFNGR1
10 pulmonary tuberculosis 29.7 IL12RB1 IFNGR1
11 bronchitis 29.7 LACTB CXCL8
12 lymphadenitis 29.6 IL12RB1 IFNGR1 CXCL8
13 immunodeficiency 28 11.4
14 mycobacterium chelonae 10.7
15 lung disease 10.7
16 peritonitis 10.6
17 mycobacterium abscessus 10.5
18 keratitis, hereditary 10.5
19 achalasia 10.4
20 mycobacterium kansasii 10.4
21 pleural empyema 10.4
22 infective endocarditis 10.4
23 mastitis 10.4
24 cervical adenitis 10.4
25 human immunodeficiency virus type 1 10.3
26 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.3
27 breast abscess 10.3
28 acute cystitis 10.3
29 corneal ulcer 10.3
30 lupus erythematosus 10.3
31 bronchiectasis 10.3
32 systemic lupus erythematosus 10.2
33 aspiration pneumonia 10.2
34 lung abscess 10.2
35 mastoiditis 10.2
36 panniculitis 10.2
37 bone inflammation disease 10.2
38 cellulitis 10.2
39 acquired immunodeficiency syndrome 10.2
40 septic arthritis 10.2
41 arthritis 10.2
42 47,xyy 10.2
43 mycobacterium marinum 10.2
44 cystic fibrosis 10.2
45 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.2
46 leprosy 3 10.2
47 leukemia, acute lymphoblastic 10.2
48 gastric cancer 10.2
49 pleurisy 10.2
50 lymphocytic leukemia 10.2

Graphical network of the top 20 diseases related to Mycobacterium Fortuitum:



Diseases related to Mycobacterium Fortuitum

Symptoms & Phenotypes for Mycobacterium Fortuitum

Drugs & Therapeutics for Mycobacterium Fortuitum

Drugs for Mycobacterium Fortuitum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 interferons Phase 1
2 Antiviral Agents Phase 1
3 Interferon-gamma Phase 1
4 Anti-Infective Agents Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Study of Adjuvant Cytokine Therapy in Pulmonary Mycobacterium Avium Complex and Other Pulmonary Nontuberculous Mycobacterial Infections Completed NCT00111397 Phase 1 Interferon Gamma, GM-CSF
2 The Incidence of Nontuberculous Mycobacterial Pulmonary Infection in Bilateral Bronchiectasis and Bronchiolitis Unknown status NCT01354912
3 Natural History, Genetics, Phenotype and Treatment of Mycobacterial Infections Recruiting NCT00018044

Search NIH Clinical Center for Mycobacterium Fortuitum

Genetic Tests for Mycobacterium Fortuitum

Anatomical Context for Mycobacterium Fortuitum

MalaCards organs/tissues related to Mycobacterium Fortuitum:

41
Skin, Lung, Testes, Bone, Lymph Node, Eye, Breast

Publications for Mycobacterium Fortuitum

Articles related to Mycobacterium Fortuitum:

(show top 50) (show all 1276)
# Title Authors PMID Year
1
Clinical and laboratory aspects of the diagnosis and management of cutaneous and subcutaneous infections caused by rapidly growing mycobacteria. 38 6
23139042 2013
2
Failure among Patients with Non-Tuberculous Mycobacterial Infections in Skin, Soft Tissue, and Musculoskeletal System in Southern Taiwan, 2012-2015. 38
31066636 2019
3
A case of pleural effusion caused by Mycobacterium fortuitum and Mycobacterium mageritense coinfection. 38
31416441 2019
4
Mycobacterium fortuitum infection of a hemodialysis catheter in a pediatric patient. 38
30746835 2019
5
Cardiovascular implantable electronic device infection with rapidly growing mycobacteria. 38
31384195 2019
6
Preliminary evaluation of the positively and negatively charge effects of tetra-substituted porphyrins on photoinactivation of rapidly growing mycobacteria. 38
31378267 2019
7
Species Distribution and Macrolide Susceptibility of Mycobacterium fortuitum Complex Clinical Isolates. 38
30885902 2019
8
INNO-LiPA DNA line probe assay misidentification of M. smegmatis as Mycobacterium fortuitum complex. 38
31358343 2019
9
In Vitro Activities of Omadacycline against Rapidly Growing Mycobacteria. 38
30858221 2019
10
Outbreak of Nontuberculous Mycobacteria Joint Prosthesis Infections, Oregon, USA, 2010-2016. 38
31002056 2019
11
Mycobacterium fortuitum as a cause of acute CNS infection in an immune-competent girl undergoing repeated VP shunt surgeries. 38
30992281 2019
12
Ribosomal maturation factor (RimP) is essential for survival of nontuberculous mycobacteria Mycobacterium fortuitum under in vitro acidic stress conditions. 38
30863706 2019
13
Multicenter evaluation of the biochip assay for rapid detection of mycobacterial isolates in smear-positive specimens. 38
30685589 2019
14
Mycobacterium fortuitum Meningitis: Approach to Lumboperitoneal Shunt Infection. 38
30943540 2019
15
Surgical wound infection following open humeral fracture caused by Mycobacterium houstonense: a case report. 38
31014284 2019
16
Study of characteristics of mycobacteriophage - A novel tool to treat Mycobacterium spp. 38
31210161 2019
17
Cardiac resynchronization therapy-defibrillator pocket infection caused by Mycobacterium fortuitum: a case report and review of the literature. 38
30836955 2019
18
Antimicrobial susceptibility testing of Mycobacteroides (Mycobacterium) abscessus complex, Mycolicibacterium (Mycobacterium) fortuitum, and Mycobacteroides (Mycobacterium) chelonae. 38
30447882 2019
19
Species Typing of Nontuberculous Mycobacteria by Use of Deoxyribozyme Sensors. 38
30523201 2019
20
Repurposing disulfiram to target infections caused by non-tuberculous mycobacteria. 38
30753528 2019
21
Non-tuberculous mycobacterial ocular infection masquerading as choroidal tumour - a diagnostic conundrum. 38
31355123 2019
22
Visual outcomes of post-cataract endophthalmitis caused by Mycobacterium fortuitum. 38
31239722 2019
23
Exogenous lipoid pneumonia in children: A systematic review. 38
30962152 2019
24
Mycobacterium smegmatis bacteremia in an immunocompetent host. 38
30937286 2019
25
Efficacy of copper and silver as residual disinfectants in drinking water. 38
30686111 2019
26
Inactivation of two Mycobacteria by free chlorine: Effectiveness, influencing factors, and mechanisms. 38
30118940 2019
27
Comparison of polymerase chain reaction-restriction enzyme analysis method and DNA sequence analysis results in the identification of non-tuberculous mycobacteria. 38
30010392 2018
28
Medical Tourism and Postoperative Infections: A Systematic Literature Review of Causative Organisms and Empiric Treatment. 38
30489537 2018
29
Mycobacterium fortuitum-induced ER-Mitochondrial calcium dynamics promotes calpain/caspase-12/caspase-9 mediated apoptosis in fish macrophages. 38
29531827 2018
30
[Species diversity of non-tuberculous mycobacteria isolated from aquatic environments of General Pico city, Province of La Pampa (Argentina)]. 38
30579706 2018
31
In Vitro Activity of PBTZ169 against Multiple Mycobacterium Species. 38
30150479 2018
32
Epidemiology of pulmonary disease due to nontuberculous mycobacteria in Southern China, 2013-2016. 38
30413193 2018
33
Breast Implant Mycobacterial Infections: An Epidemiologic Review and Outcome Analysis. 38
30096121 2018
34
Cutaneous Nontuberculous Mycobacterial Infections in Alberta, Canada: An Epidemiologic Study and Review. 38
29772918 2018
35
High rates of Mycobacterium fortuitum isolation in respiratory samples from Iranian patients with suspected tuberculosis: is it clinically important? 38
30052175 2018
36
Post-Facelift Infection Due to Mycobacterium Fortuitum: A Case Report. 38
30084582 2018
37
TNF-α-mediated ER stress causes elimination of Mycobacterium fortuitum reservoirs by macrophage apoptosis. 38
29481309 2018
38
A totally implantable venous access port associated with bloodstream infection caused by Mycobacterium fortuitum: A case report. 38
30024528 2018
39
In Vitro Activity of Clofazimine against Nontuberculous Mycobacteria Isolated in Beijing, China. 38
29760127 2018
40
Profiling non-tuberculous mycobacteria in an Asian setting: characteristics and clinical outcomes of hospitalized patients in Singapore. 38
29788943 2018
41
Mycobacterium fortuitum infection associated with achalasia. 38
30430507 2018
42
PhdA Catalyzes the First Step of Phenazine-1-Carboxylic Acid Degradation in Mycobacterium fortuitum. 38
29483162 2018
43
Draft Genome Sequence of Mycobacterium porcinum CSURP1564. 38
29674548 2018
44
Non-tuberculous Mycobacterium species causing mycobacteriosis in farmed aquatic animals of South Africa. 38
29653505 2018
45
Lipase-catalyzed kinetic resolution of novel antitubercular benzoxazole derivatives. 38
29274237 2018
46
Recurrent Mycobacterium fortuitum insulin injection site abscesses. 38
29168906 2018
47
Non-Tuberculous Mycobacterial Infections Related to Peritoneal Dialysis. 38
29563276 2018
48
Mycobacterium Fortuitum infection associated with achalasia. 38
30325493 2018
49
Cutaneous mycobacteriosis in a captive Amazonian manatee Trichechus inunguis. 38
29516862 2018
50
Combinatorial design and virtual screening of potent anti-tubercular fluoroquinolone and isothiazoloquinolone compounds utilizing QSAR and pharmacophore modelling. 38
29347843 2018

Variations for Mycobacterium Fortuitum

Expression for Mycobacterium Fortuitum

Search GEO for disease gene expression data for Mycobacterium Fortuitum.

Pathways for Mycobacterium Fortuitum

GO Terms for Mycobacterium Fortuitum

Biological processes related to Mycobacterium Fortuitum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of interferon-gamma production GO:0032729 8.96 IL12RB1 HSPD1
2 cytokine-mediated signaling pathway GO:0019221 8.8 IL12RB1 IFNGR1 CXCL8

Molecular functions related to Mycobacterium Fortuitum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine binding GO:0019955 8.62 IL12RB1 IFNGR1

Sources for Mycobacterium Fortuitum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....