MCID: MYC018
MIFTS: 29

Mycobacterium Malmoense

Categories: Rare diseases

Aliases & Classifications for Mycobacterium Malmoense

MalaCards integrated aliases for Mycobacterium Malmoense:

Name: Mycobacterium Malmoense 53
Mycobacterium Malmoense Infection 53
M. Malmoense 53

Classifications:



Summaries for Mycobacterium Malmoense

NIH Rare Diseases : 53 Mycobacterium malmoense (M. malmoense) is a bacterium naturally found in the environment, such as in wet soil, house dust, water, dairy products, domestic and wild animals, food, and human waste. M. malmoense infections most often occur in adults with lung disease, and manifests as a lung infection. Skin and tissue infections with M. malmoense have also been described. In young children, M. Malmoense may cause an infection of lymphnodes in the neck (i.e., cervical lymphadenitis).

MalaCards based summary : Mycobacterium Malmoense, also known as mycobacterium malmoense infection, is related to cervical adenitis and arthritis. An important gene associated with Mycobacterium Malmoense is CD1A (CD1a Molecule), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. The drugs Rifampicin and Clarithromycin have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and kidney.

Wikipedia : 76 Mycobacterium malmoense is a Gram-positive bacterium from the genus... more...

Related Diseases for Mycobacterium Malmoense

Diseases related to Mycobacterium Malmoense via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
# Related Disease Score Top Affiliating Genes
1 cervical adenitis 10.3
2 arthritis 10.2
3 pneumoconiosis 10.2
4 lymphadenitis 10.2
5 septic arthritis 10.2
6 lung disease 10.2
7 tenosynovitis 10.2
8 carpal tunnel syndrome 10.1
9 mononeuropathy of the median nerve, mild 10.1
10 myelodysplastic syndrome 10.1
11 leukemia 10.1
12 salmonellosis 10.1
13 anthracosis 10.1
14 hairy cell leukemia 10.1
15 bursitis 10.1
16 mycobacterium marinum 10.1
17 multifocal motor neuropathy 9.8 CD1A CD1E
18 thymus lipoma 9.6 CD1A CD1B CD1C
19 immune system organ benign neoplasm 9.5 CD1A CD1B CD1C

Graphical network of the top 20 diseases related to Mycobacterium Malmoense:



Diseases related to Mycobacterium Malmoense

Symptoms & Phenotypes for Mycobacterium Malmoense

Drugs & Therapeutics for Mycobacterium Malmoense

Drugs for Mycobacterium Malmoense (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Rifampicin Approved Phase 4 13292-46-1 5458213 5381226
2
Clarithromycin Approved Phase 4 81103-11-9 84029
3
Ethambutol Approved Phase 4 74-55-5 3279 14052
4
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
5 Cytochrome P-450 CYP3A Inhibitors Phase 4
6 Antitubercular Agents Phase 4
7 Cytochrome P-450 CYP3A Inducers Phase 4
8 Nucleic Acid Synthesis Inhibitors Phase 4
9 Antibiotics, Antitubercular Phase 4
10 Anti-Bacterial Agents Phase 4
11 Topoisomerase Inhibitors Phase 4
12 Anti-Infective Agents Phase 4
13 Cytochrome P-450 Enzyme Inhibitors Phase 4
14 Vaccines Phase 4
15 Cytochrome P-450 CYP1A2 Inhibitors Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clarithromycin v Ciprofloxacin Added to Rifampicin + Ethambutol, for Opportunist Mycobacterial Pulmonary Disease Completed NCT00367913 Phase 4 Addition of clarithromycin to rifampicin and ethambutol;Addition of Ciprofloxacin to rifampicin and ethambutol

Search NIH Clinical Center for Mycobacterium Malmoense

Genetic Tests for Mycobacterium Malmoense

Anatomical Context for Mycobacterium Malmoense

MalaCards organs/tissues related to Mycobacterium Malmoense:

41
Lung, Skin, Kidney, Thymus

Publications for Mycobacterium Malmoense

Articles related to Mycobacterium Malmoense:

(show top 50) (show all 91)
# Title Authors Year
1
Tenosynovitis caused by Mycobacterium malmoense in two kidney transplant recipients and review of the literature. ( 29125666 )
2018
2
Pulmonary Cavity From<i>Mycobacterium malmoense</i>in an HIV-Infected Patient: Complicated by Bronchopleural Fistula. ( 29450215 )
2018
3
Dissemination of localized Mycobacterium malmoense infection in an immunocompromised patient. ( 30201506 )
2018
4
Mycobacterium malmoense pulmonary infection in France: a case report. ( 28859675 )
2017
5
Disseminated Mycobacterium malmoense and Salmonella Infections Associated with a Novel Variant in NFKBIA. ( 28417298 )
2017
6
Pulmonary cavity due to Mycobacterium malmoense: Diagnosis with bronchoalveolar lavage following percutaneous instillation of normal saline. ( 27955841 )
2016
7
Lung Disease Caused by Mycobacterium malmoense in an Immunocompetent Patient. ( 26175789 )
2015
8
Voluminous pseudotumor due to Mycobacterium malmoense. ( 22503351 )
2013
9
Disseminated infection with cutaneous involvement caused by Mycobacterium malmoense in an immunocompromised patient. ( 24034397 )
2013
10
Mycobacterium malmoense: dissemination causes a popliteal aneurysm in a 74-year-old man. ( 22602841 )
2012
11
Infrapatellar bursitis with Mycobacterium malmoense related to immune reconstitution inflammatory syndrome in an HIV-positive patient. ( 23188870 )
2012
12
Cervical abscess in an immunocompetent patient with Mycobacterium malmoense pulmonary disease. ( 22057954 )
2012
13
Mycobacterium malmoense as an extrapulmonary pathogen of cats. ( 22865116 )
2012
14
No human transmission of Mycobacterium malmoense in a perfect storm setting. ( 23204026 )
2012
15
Mycobacterium malmoense: an underestimated nontuberculous mycobacterium. ( 19733030 )
2010
16
Cervical lymphadenitis due to Mycobacterium malmoense. ( 20417008 )
2010
17
An association between Mycobacterium malmoense and coal workers' pneumoconiosis. ( 18758857 )
2009
18
Pulmonary Infection Due to Mycobacterium malmoense in a Patient with Crohn Disease. ( 22478938 )
2009
19
Clinical relevance of Mycobacterium malmoense isolation in The Netherlands. ( 19386689 )
2009
20
A 10-year history of Mycobacterium malmoense septic arthritis of the wrist. ( 19956010 )
2009
21
The rising incidence and clinical relevance of Mycobacterium malmoense: a review of the literature. ( 18713494 )
2008
22
The first surgical treatment case of pulmonary Mycobacterium malmoense infection in Japan. ( 19075549 )
2008
23
Isolation of Mycobacterium malmoense in the island of Crete, Greece. ( 18695331 )
2008
24
Mycobacterium malmoense and underlying lung disease. ( 19013363 )
2008
25
Reduced TH-1 cytokine release in an adult patient with chronic relapsing Mycobacterium malmoense infection. ( 17646921 )
2007
26
First Canadian Reports of Cervical Adenitis Due to Mycobacterium Malmoense and a 10-year Review of Nontuberculous Mycobacterial Adenitis. ( 18418488 )
2006
27
A mutation in the 65,000 Dalton heat shock protein gene, commonly used for molecular identification of non-tuberculous mycobacteria, leads to the misidentification of Mycobacterium malmoense as Mycobacterium marinum. ( 16002259 )
2005
28
Mycobacterium malmoense lymphadenitis in Spain: first two cases in immunocompetent patients. ( 15257445 )
2004
29
Mycobacterium malmoense infection of the knee. ( 14583565 )
2003
30
Mycobacterium malmoense septic arthritis. ( 12504611 )
2003
31
Molecular epidemiology of Mycobacterium malmoense infections in Scotland. ( 11880453 )
2002
32
Molecular characterization of a Spanish isolate of Mycobacterium malmoense. ( 11881896 )
2002
33
Disseminated disease with Mycobacterium malmoense in a patient with pneumoconiosis. ( 11798264 )
2001
34
CD1 genotyping of patients with Mycobacterium malmoense pulmonary disease. ( 11580851 )
2001
35
Vitamin D receptor gene polymorphisms and susceptibility to Mycobacterium malmoense pulmonary disease. ( 10837203 )
2000
36
Mycobacterium malmoense infections in immunocompetent patients. ( 10517195 )
1999
37
Mycobacterium malmoense-specific nested PCR based on a conserved sequence detected in random amplified polymorphic DNA fingerprints. ( 10203504 )
1999
38
Mycobacterium malmoense infection. An unusual cause of wrist swelling. ( 9888690 )
1998
39
Pulmonary disease due to Mycobacterium malmoense in British Columbia. ( 9707456 )
1998
40
Mycobacterium malmoense infections in the United States, January 1993 through June 1995. ( 9770156 )
1998
41
Susceptibilities of Mycobacterium malmoense determined at the growth optimum pH (pH 6.0). ( 9613641 )
1998
42
Mycobacterium malmoense in Italy: the modern Norman invasion? ( 9258535 )
1997
43
Flexor tenosynovitis in the hand caused by Mycobacterium malmoense: a case report. ( 9195437 )
1997
44
Mycobacterium malmoense bacteremia in two AIDS patients. ( 8904448 )
1996
45
Application of a PCR based DNA probe for the rapid identification of Mycobacterium malmoense isolated from a case of cervical adenitis. ( 8945716 )
1996
46
A Mycobacterium malmoense-specific DNA probe from the 16S/23S rRNA intergenic spacer region. ( 8910888 )
1996
47
Bronchopulmonary infection with Mycobacterium malmoense presenting as a bronchoesophageal fistula. ( 8758116 )
1996
48
Isolation of Mycobacterium malmoense from the environment in Zaire. ( 7780099 )
1995
49
Pulmonary Mycobacterium malmoense and Aspergillus infection. ( 7701472 )
1995
50
Mycobacterium malmoense in Italy. ( 7780102 )
1995

Variations for Mycobacterium Malmoense

Expression for Mycobacterium Malmoense

Search GEO for disease gene expression data for Mycobacterium Malmoense.

Pathways for Mycobacterium Malmoense

GO Terms for Mycobacterium Malmoense

Cellular components related to Mycobacterium Malmoense according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of membrane GO:0016021 9.8 CD1A CD1B CD1C CD1D CD1E
2 plasma membrane GO:0005886 9.77 CD1A CD1B CD1C CD1D CD1E
3 integral component of plasma membrane GO:0005887 9.62 CD1A CD1C CD1D CD1E
4 lysosome GO:0005764 9.56 CD1B CD1C CD1D CD1E
5 endosome membrane GO:0010008 9.46 CD1A CD1B CD1C CD1D
6 lysosomal membrane GO:0005765 9.43 CD1B CD1D
7 cell surface GO:0009986 9.35 CD1A CD1B CD1C CD1D CD1E
8 endosome GO:0005768 9.02 CD1A CD1B CD1C CD1D CD1E

Biological processes related to Mycobacterium Malmoense according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune system process GO:0002376 9.72 CD1A CD1B CD1C CD1D CD1E
2 adaptive immune response GO:0002250 9.71 CD1A CD1B CD1C CD1E
3 regulation of immune response GO:0050776 9.67 CD1A CD1B CD1C CD1D
4 immune response GO:0006955 9.65 CD1A CD1B CD1C CD1D CD1E
5 positive regulation of T cell mediated cytotoxicity GO:0001916 9.55 CD1A CD1B CD1C CD1D CD1E
6 antigen processing and presentation, endogenous lipid antigen via MHC class Ib GO:0048006 9.35 CD1A CD1B CD1C CD1D CD1E
7 antigen processing and presentation, exogenous lipid antigen via MHC class Ib GO:0048007 9.02 CD1A CD1B CD1C CD1D CD1E

Molecular functions related to Mycobacterium Malmoense according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endogenous lipid antigen binding GO:0030883 9.55 CD1A CD1B CD1C CD1D CD1E
2 exogenous lipid antigen binding GO:0030884 9.35 CD1A CD1B CD1C CD1D CD1E
3 lipopeptide binding GO:0071723 9.02 CD1A CD1B CD1C CD1D CD1E

Sources for Mycobacterium Malmoense

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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