TB
MCID: MYC084
MIFTS: 74

Mycobacterium Tuberculosis 1 (TB)

Categories: Blood diseases, Endocrine diseases, Immune diseases, Infectious diseases, Rare diseases, Reproductive diseases, Respiratory diseases

Aliases & Classifications for Mycobacterium Tuberculosis 1

MalaCards integrated aliases for Mycobacterium Tuberculosis 1:

Name: Mycobacterium Tuberculosis 1 57
Tuberculosis 57 12 76 53 59 55 43 3 15 73
Tuberculosis, Susceptibility to 57 13 6
Tb 53 48 3
Tuberculoma 44 73
Mycobacterium Tuberculosis, Susceptibility to, 1 57
Kochs Disease 53
Mtbs1 57

Classifications:



External Ids:

OMIM 57 607949
Disease Ontology 12 DOID:399
MeSH 44 D014375
SNOMED-CT 68 15202009
Orphanet 59 ORPHA3389
MESH via Orphanet 45 D014376
UMLS via Orphanet 74 C0041296
ICD10 33 A15-A19 A17.9

Summaries for Mycobacterium Tuberculosis 1

MedlinePlus : 43 Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but they can also damage other parts of the body. TB spreads through the air when a person with TB of the lungs or throat coughs, sneezes, or talks. If you have been exposed, you should go to your doctor for tests. You are more likely to get TB if you have a weak immune system. Symptoms of TB in the lungs may include A bad cough that lasts 3 weeks or longer Weight loss Loss of appetite Coughing up blood or mucus Weakness or fatigue Fever Night sweats Skin tests, blood tests, x-rays, and other tests can tell if you have TB. If not treated properly, TB can be deadly. You can usually cure active TB by taking several medicines for a long period of time. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Mycobacterium Tuberculosis 1, also known as tuberculosis, is related to miliary tuberculosis and pleural tuberculosis, and has symptoms including fever, pruritus and snoring. An important gene associated with Mycobacterium Tuberculosis 1 is CD244 (CD244 Molecule), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. Affiliated tissues include testes, lung and skin, and related phenotypes are fever and fatigue

Disease Ontology : 12 A primary bacterial infectious disease that is located in lungs, located in lymph nodes, located in pericardium, located in brain, located in pleura or located in gastrointestinal tract, has material basis in Mycobacterium tuberculosis, which is transmitted by droplets released into the air when an infected person coughs or sneezes.

NIH Rare Diseases : 53 Tuberculosis (TB) is a contagious and often severe airborne disease caused by the TB bacterium, Mycobacterium tuberculosis. TB typically affects the lungs, but other organs of the body may be involved, as well. Not everyone who is infected with the TB bacterium becomes sick. TB bacterial infections only become "active disease" if the immune system can't stop them from growing. Classic signs and symptoms of active TB can include cough, weight loss, fever, night sweats, hemoptysis, chest pain, and fatigue. Symptoms involving areas of the body other than the lungs vary depending on which organ(s) are affected. TB is usually treated with a regimen of medications taken over a long period of time (often six to twelve months).

CDC : 3 Patient Education Materials, Fact Sheets, Brochures, Reports & Articles, Slide Sets, Posters, Infographics, Electronic Tools & Resources, Find TB Resources, Newsletters, Guidelines, Webinars

Wikipedia : 76 Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis... more...

Description from OMIM: 607949

Related Diseases for Mycobacterium Tuberculosis 1

Diseases in the Mycobacterium Tuberculosis 1 family:

Mycobacterium Tuberculosis 2 Mycobacterium Tuberculosis 3

Diseases related to Mycobacterium Tuberculosis 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1232)
# Related Disease Score Top Affiliating Genes
1 miliary tuberculosis 34.5 ADA IFNG IL12RB1 TNF
2 pleural tuberculosis 34.3 ADA IFNG TNF
3 multidrug-resistant tuberculosis 34.2 IL10 INHA SLC11A1 TNF
4 extrapulmonary tuberculosis 34.1 ADA IFNG IL10 SLC11A1 TLR2
5 abdominal tuberculosis 34.1 ADA IL12RB1
6 pericardial tuberculosis 33.9 ADA IFNG IL10
7 tuberculous meningitis 33.3 ADA TLR2 TNF
8 tuberculous peritonitis 32.8 ADA IFNG TNF
9 acquired immunodeficiency syndrome 32.4 IFNG IL10 TNF
10 mycobacterium fortuitum 32.3 HSPD1 IFNGR1 IL12RB1
11 nontuberculous mycobacterial lung disease 32.3 SLC11A1 TLR2 TNF
12 aspergillosis 32.3 CD209 IFNG IL10 IL4 TLR2 TLR9
13 lung disease 32.3 IL10 TLR2 TLR9 TNF
14 melioidosis 32.3 IFNG IL10 TLR2 TNF
15 orofacial granulomatosis 32.2 IFNG IL10 IL4 TNF
16 buruli ulcer 32.2 IFNG IL10 IL4 SLC11A1
17 mycobacterium tuberculosis, susceptibility to infection by 32.2 MTBS1 SLC11A1
18 human immunodeficiency virus type 1 32.2 ADA CD209 IFNG IL10 TNF
19 macs syndrome 31.8 IFNGR1 IL12RB1 SLC11A1
20 crohn's disease 31.1 IL10 SLC11A1 TLR9 TNF
21 meningitis 31.0 ADA IFNG IL10 TLR2 TLR9 TNF
22 pneumonia 31.0 IL10 TLR2 TLR9 TNF
23 human immunodeficiency virus infectious disease 30.9 IFNG IL10 TLR9 TNF
24 lymphadenitis 30.8 CD209 IFNG IFNGR1 IL10 IL12RB1 SLC11A1
25 pleurisy 30.8 ADA IFNG TNF
26 uveitis 30.7 IFNG IL10 IL4 TNF
27 rheumatoid arthritis 30.7 CD244 IFNG IL10 IL4 SLC11A1 TLR2
28 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 30.7 CD209 IFNG IL10 IL4
29 nocardiosis 30.7 HSPD1 IL12RB1
30 peritonitis 30.6 ADA IL10 TLR2 TNF
31 systemic lupus erythematosus 30.6 IFNG IL10 IL4 TLR2 TLR9 TNF
32 viral hepatitis 30.6 TLR2 TLR9 TNF
33 cryptococcosis 30.5 IFNG IL4 TLR9
34 brucellosis 30.5 IFNG IL10 IL4 SLC11A1 TNF
35 pericarditis 30.5 ADA IFNG TNF
36 osteomyelitis 30.5 IFNG IFNGR1 IL10 TNF
37 rheumatic disease 30.5 IFNG IL10 TLR9 TNF
38 sarcoidosis 1 30.5 IFNG IL12RB1 SLC11A1 TNF
39 multifocal choroiditis 30.4 IL10 TNF
40 viral infectious disease 30.4 CD209 IFNG IL10 IL4 TLR9 TNF
41 otitis media 30.4 IL10 IL4 TLR2 TNF
42 hemophagocytic lymphohistiocytosis 30.3 CD244 IFNG IL10 TNF
43 lepromatous leprosy 30.3 IFNG IFNGR1 IL10 IL12RB1 TLR2 TNF
44 inflammatory bowel disease 30.3 IFNG IFNGR1 IL10 IL4 SLC11A1 TLR2
45 paracoccidioidomycosis 30.3 IFNG IL10 IL4 TLR2 TNF
46 scleritis 30.3 IFNG IL4 TNF
47 eales disease 30.3 IFNG IL10 IL4 TNF
48 sporotrichosis 30.2 IFNG IL10
49 malaria 30.2 CISH IFNG IFNGR1 IL10 IL4 TLR2
50 psoriasis 30.2 IFNG IL10 IL4 TLR9 TNF

Graphical network of the top 20 diseases related to Mycobacterium Tuberculosis 1:



Diseases related to Mycobacterium Tuberculosis 1

Symptoms & Phenotypes for Mycobacterium Tuberculosis 1

Clinical features from OMIM:

607949

Human phenotypes related to Mycobacterium Tuberculosis 1:

59 32 (show all 6)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 fever 59 32 frequent (33%) Frequent (79-30%) HP:0001945
2 fatigue 59 32 frequent (33%) Frequent (79-30%) HP:0012378
3 weight loss 59 32 frequent (33%) Frequent (79-30%) HP:0001824
4 cough 59 32 frequent (33%) Frequent (79-30%) HP:0012735
5 abnormality of lung morphology 59 Frequent (79-30%)
6 abnormal lung morphology 32 frequent (33%) HP:0002088

UMLS symptoms related to Mycobacterium Tuberculosis 1:


fever, pruritus, snoring, coughing

MGI Mouse Phenotypes related to Mycobacterium Tuberculosis 1:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.13 ADA CD244 CISH IFNG IFNGR1 IL10
2 digestive/alimentary MP:0005381 10.1 ADA IFNG IFNGR1 IL10 IL4 INHA
3 immune system MP:0005387 10.07 ADA CD244 CISH IFNG IFNGR1 IL10
4 endocrine/exocrine gland MP:0005379 10.02 ADA CISH IFNG IFNGR1 IL10 IL4
5 liver/biliary system MP:0005370 9.76 ADA IFNG IFNGR1 IL10 IL4 INHA
6 neoplasm MP:0002006 9.5 IFNG IFNGR1 IL10 INHA SLC11A1 TLR2
7 respiratory system MP:0005388 9.17 ADA CISH IFNG IL10 IL4 TLR2

Drugs & Therapeutics for Mycobacterium Tuberculosis 1

Search Clinical Trials , NIH Clinical Center for Mycobacterium Tuberculosis 1

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: tuberculoma

Genetic Tests for Mycobacterium Tuberculosis 1

Anatomical Context for Mycobacterium Tuberculosis 1

MalaCards organs/tissues related to Mycobacterium Tuberculosis 1:

41
Testes, Lung, Skin, T Cells, Liver, Lymph Node, Kidney

The Foundational Model of Anatomy Ontology organs/tissues related to Mycobacterium Tuberculosis 1:

19
Lungs, Brain, Pericardium, Lymph Nodes, Pleura Or

Publications for Mycobacterium Tuberculosis 1

Articles related to Mycobacterium Tuberculosis 1:

(show top 50) (show all 999)
# Title Authors Year
1
Chemical composition of Acacia farnesiana (L) wild fruits and its activity against Mycobacterium tuberculosis and dysentery bacteria. ( 30367988 )
2019
2
HIV/tuberculosis/hepatitis C virus services for incarcerated populations in Azerbaijan and the Eastern Europe Central Asia region. ( 30489347 )
2019
3
Creating demand for long-acting formulations for the treatment and prevention of HIV, tuberculosis, and viral hepatitis. ( 30394948 )
2019
4
A novel aptamer-based test for the rapid and accurate diagnosis of pleural tuberculosis. ( 30352198 )
2019
5
Epidemiology and diagnosis of pleural tuberculosis in a low incidence country with high rate of immigrant population: A retrospective study. ( 30449728 )
2019
6
Household fuel use and pulmonary tuberculosis in western Nepal: A case-control study. ( 30317104 )
2019
7
History of Pulmonary Tuberculosis. ( 30454916 )
2019
8
Current Medical Management of Pulmonary Tuberculosis. ( 30454919 )
2019
9
Surgical Resection in the Treatment of Pulmonary Tuberculosis. ( 30454920 )
2019
10
Modern Collapse Therapy for Pulmonary Tuberculosis. ( 30454921 )
2019
11
Cognitive Impairment in Zambians With HIV Infection and Pulmonary Tuberculosis. ( 30531294 )
2019
12
Long-lasting cutaneous tuberculosis owing to Mycobacterium bovis masquerading as sarcoidosis. ( 30533472 )
2019
13
Proximate determinants of tuberculosis in Indigenous peoples worldwide: a systematic review. ( 30554764 )
2019
14
Determinants of tuberculosis in Indigenous people worldwide. ( 30554763 )
2019
15
Advances and challenges in drug design against tuberculosis: application of in silico approaches. ( 30477360 )
2019
16
Detection of the tuberculosis biomarker mannose-capped lipoarabinomannan in human serum: Impact of sample pretreatment with perchloric acid. ( 30482291 )
2019
17
Dynamic time-kill curve characterization of spectinamide antibiotics 1445 and 1599 for the treatment of tuberculosis. ( 30419293 )
2019
18
Use of Liquid Chromatography-Mass Spectrometry-Based Metabolomics to Identify Biomarkers of Tuberculosis. ( 30421233 )
2019
19
Tuberculosis in Children. ( 30454917 )
2019
20
The Global Fight Against Tuberculosis. ( 30454918 )
2019
21
Rare radiological features of abdominopelvic tuberculosis: A case report. ( 30377456 )
2019
22
Design, synthesis and antitubercular activity of 4-alkoxy-triazoloquinolones able to inhibit the M. tuberculosis DNA gyrase. ( 30384044 )
2019
23
Inhalable poly(lactic-co-glycolic acid) (PLGA) microparticles encapsulating all-trans-Retinoic acid (ATRA) as a host-directed, adjunctive treatment for Mycobacterium tuberculosis infection. ( 30385419 )
2019
24
Demanding an end to tuberculosis: treatment of tuberculosis infection among persons living with and without HIV. ( 30407203 )
2019
25
Diagnosing active tuberculosis in people living with HIV: an ongoing challenge. ( 30346311 )
2019
26
Colorimetric Detection of MPT64 Antibody Based on an Aptamer Adsorbed Magnetic Nanoparticles for Diagnosis of Tuberculosis. ( 30360132 )
2019
27
Estimating the annual risk of tuberculosis infection in Japan from interferon-gamma release assay data. ( 30315813 )
2019
28
Exosomes in tuberculosis: Still terra incognita? ( 30317619 )
2019
29
Process parameters optimization to produce the recombinant protein CFP10 for the diagnosis of tuberculosis. ( 30261310 )
2019
30
Identification and validation of l-asparaginase as a potential metabolic target against Mycobacterium tuberculosis. ( 30230585 )
2019
31
Use of steroids for abdominal tuberculosis: a systematic review and meta-analysis. ( 30324229 )
2018
32
Defining 'satisfactory response' to therapy in abdominal tuberculosis : A work in progress. ( 30345933 )
2018
33
Role of Ultrasound-Guided Fine-Needle Aspiration Cytology of Omentum in Diagnosis of Abdominal Tuberculosis. ( 30481127 )
2018
34
Risk factors for acute liver failure among inpatients with anti-tuberculosis drug-induced liver injury. ( 30477373 )
2018
35
Noncaseating suppurative granulomatous lymphadenitis in adult onset Still's disease - a diagnostic dilemma in a tuberculosis-endemic region: a case report. ( 30318016 )
2018
36
Combined testing for herpes simplex virus and Mycobacterium tuberculosis DNA in cerebrospinal fluid of patients with aseptic meningitis in Burkina Faso, West Africa. ( 30474140 )
2018
37
Chronic pulmonary aspergillosis after pulmonary tuberculosis. ( 30274995 )
2018
38
Inhaled Corticosteroid-Related Tuberculosis in the Real World Among Patients with Asthma and COPD: A 10-Year Nationwide Population-Based Study. ( 30339858 )
2018
39
Does chronic immunosuppressive therapy for autoimmune disease influence the risk of developing active tuberculosis? ( 30371983 )
2018
40
Disseminated blastomycosis with cutaneous lesions mimicking tuberculosis. ( 30507461 )
2018
41
Elevated interleukin-6 and bronchiectasis as risk factors for acute exacerbation in patients with tuberculosis-destroyed lung with airflow limitation. ( 30416771 )
2018
42
Arterial embolization for hemoptysis in patients with chronic pulmonary tuberculosis and in patients with bronchiectasis. ( 30282481 )
2018
43
The prevalence of brucellosis and bovine tuberculosis in ruminants in Sidi Kacem Province, Morocco. ( 30226847 )
2018
44
Central Nervous System Tuberculosis : Etiology, Clinical Manifestations and Neuroradiological Features. ( 30225516 )
2018
45
Central nervous system tuberculosis following delayed and initially missed lung miliary tuberculosis: a case report. ( 30246772 )
2018
46
Study of Central Nervous System Tuberculosis. ( 30341844 )
2018
47
Atypical Clinical Presentation and Imaging Findings of Central Nervous System Tuberculosis. ( 30430973 )
2018
48
Primary hepatic tuberculosis masquerading as cholangiocarcinoma: A clinical nugget. ( 30541722 )
2018
49
Specific cholecystitis: An unusual presentation of extrapulmonary tuberculosis. ( 30243911 )
2018
50
CD73 expression in tissue granulomas in distinguishing intestinal tuberculosis from Crohn's disease in a South African cohort. ( 30295112 )
2018

Variations for Mycobacterium Tuberculosis 1

ClinVar genetic disease variations for Mycobacterium Tuberculosis 1:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 CISH NM_013324.5(CISH): c.-524T> A single nucleotide variant risk factor rs414171 GRCh37 Chromosome 3, 50649499: 50649499
2 CISH NM_013324.5(CISH): c.-524T> A single nucleotide variant risk factor rs414171 GRCh38 Chromosome 3, 50612068: 50612068

Expression for Mycobacterium Tuberculosis 1

Search GEO for disease gene expression data for Mycobacterium Tuberculosis 1.

Pathways for Mycobacterium Tuberculosis 1

Pathways related to Mycobacterium Tuberculosis 1 according to GeneCards Suite gene sharing:

(show all 37)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14 CD209 CISH IFNG IFNGR1 IL10 IL12RB1
2
Show member pathways
13.32 CISH IFNG IFNGR1 IL10 IL12RB1 IL4
3
Show member pathways
12.99 CISH IFNG IFNGR1 IL10 TLR2 TLR9
4
Show member pathways
12.86 HSPD1 IFNG IFNGR1 IL10 IL12RB1 IL4
5
Show member pathways
12.77 CD209 IFNG IFNGR1 IL4 TLR2 TLR9
6
Show member pathways
12.62 IFNG IFNGR1 IL10 IL12RB1 IL4 TNF
7
Show member pathways
12.54 IFNG IFNGR1 IL10 IL12RB1 IL4 TLR2
8
Show member pathways
12.5 CD244 IFNG IFNGR1 IL4 TNF
9 12.49 CISH IFNG IL10 IL4 TLR2 TLR9
10
Show member pathways
12.39 CISH IFNG IFNGR1 IL10 IL12RB1 IL4
11
Show member pathways
12.38 IFNG IL10 IL4 TNF
12
Show member pathways
12.29 IFNG IL4 TLR2 TNF
13
Show member pathways
12.23 IFNG IFNGR1 IL10 IL4 TLR2 TNF
14
Show member pathways
12.19 CD209 IL10 TLR9 TNF
15 12.17 IFNG IFNGR1 TLR2 TLR9 TNF
16
Show member pathways
12.1 IFNG IFNGR1 IL4 TLR2 TLR9 TNF
17
Show member pathways
12.02 HSPD1 IFNG IL4 TLR2 TNF
18 11.88 IFNG IL10 TLR2 TNF
19 11.86 IFNG IFNGR1 IL10 IL12RB1
20 11.86 CD209 CD244 IFNG IL10 IL4 TNF
21 11.8 IFNG TLR2 TNF
22
Show member pathways
11.72 IFNG IL4 TNF
23 11.72 IFNG IL10 IL4 TNF
24 11.64 CD244 IFNG IL10 IL12RB1 IL4 TNF
25
Show member pathways
11.61 IFNG IFNGR1 IL10 IL12RB1 TLR2 TLR9
26 11.57 HSPD1 TLR2 TNF
27
Show member pathways
11.52 IFNG IFNGR1 TNF
28 11.5 IL10 IL4 TNF
29 11.5 CD209 CD244 IFNG IL10 TLR9 TNF
30 11.49 IFNG TLR2 TNF
31 11.48 CD209 HSPD1 IFNG IFNGR1 IL10 TLR2
32 11.47 IFNG IL10 IL4
33 11.46 IFNG IL10 TLR2 TLR9 TNF
34 11.36 IFNG IL10 TLR9 TNF
35 11.29 IFNG IL4 TNF
36 11.26 IFNG IL10 IL4 TNF
37 11.2 IFNG IL10 IL4

GO Terms for Mycobacterium Tuberculosis 1

Cellular components related to Mycobacterium Tuberculosis 1 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.02 ADA CD209 CD244 IL12RB1 TNF

Biological processes related to Mycobacterium Tuberculosis 1 according to GeneCards Suite gene sharing:

(show all 45)
# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.97 IL10 SLC11A1 TLR9 TNF
2 response to lipopolysaccharide GO:0032496 9.92 HSPD1 IL10 SLC11A1 TLR2
3 cytokine-mediated signaling pathway GO:0019221 9.92 IFNGR1 IL10 IL12RB1 IL4 TNF
4 positive regulation of gene expression GO:0010628 9.91 IFNG IL4 SLC11A1 TLR2 TLR9 TNF
5 response to organic substance GO:0010033 9.86 HSPD1 IL10 TNF
6 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.85 HSPD1 HSPE1 TNF
7 response to glucocorticoid GO:0051384 9.83 HSPD1 IL10 TNF
8 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.81 TLR2 TLR9 TNF
9 T cell activation GO:0042110 9.79 ADA HSPD1 IL4
10 interleukin-12-mediated signaling pathway GO:0035722 9.77 IFNG IL10 IL12RB1
11 positive regulation of B cell proliferation GO:0030890 9.74 ADA IL4 TLR9
12 MyD88-dependent toll-like receptor signaling pathway GO:0002755 9.71 HSPD1 TLR2 TLR9
13 negative regulation of growth of symbiont in host GO:0044130 9.7 IL10 TNF
14 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.69 IL10 TNF
15 positive regulation of interleukin-8 secretion GO:2000484 9.69 CD244 TLR2
16 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.69 TLR2 TLR9
17 negative regulation of interleukin-6 production GO:0032715 9.69 IL10 TLR9 TNF
18 regulation of cytokine secretion GO:0050707 9.68 TLR2 TLR9
19 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.68 IFNG IFNGR1
20 I-kappaB phosphorylation GO:0007252 9.67 TLR2 TLR9
21 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.67 TLR9 TNF
22 positive regulation of interleukin-8 production GO:0032757 9.67 TLR2 TLR9 TNF
23 positive regulation of inflammatory response GO:0050729 9.67 HSPD1 TLR2 TLR9 TNF
24 positive regulation of T-helper 1 type immune response GO:0002827 9.66 IL12RB1 SLC11A1
25 endothelial cell apoptotic process GO:0072577 9.65 IL10 TNF
26 negative regulation of interleukin-8 production GO:0032717 9.65 IL10 TLR9
27 positive regulation of MHC class II biosynthetic process GO:0045348 9.64 IL10 IL4
28 negative regulation of cytokine secretion involved in immune response GO:0002740 9.64 IL10 TNF
29 positive regulation of interleukin-10 production GO:0032733 9.63 HSPD1 TLR2 TLR9
30 positive regulation of interleukin-6 production GO:0032755 9.62 HSPD1 TLR2 TLR9 TNF
31 positive regulation of interleukin-18 production GO:0032741 9.61 TLR2 TLR9
32 tumor necrosis factor production GO:0032640 9.61 TLR2 TLR9
33 positive regulation of toll-like receptor signaling pathway GO:0034123 9.59 TLR2 TLR9
34 regulation of isotype switching GO:0045191 9.58 IL10 IL4
35 type 2 immune response GO:0042092 9.58 IL10 IL4
36 positive regulation of chemokine production GO:0032722 9.58 TLR2 TLR9 TNF
37 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.56 IFNG TNF
38 receptor biosynthetic process GO:0032800 9.55 IL10 TNF
39 positive regulation of vitamin D biosynthetic process GO:0060557 9.48 IFNG TNF
40 positive regulation of interferon-gamma production GO:0032729 9.46 HSPD1 IL12RB1 SLC11A1 TNF
41 response to molecule of bacterial origin GO:0002237 9.43 IL10 TLR2 TLR9
42 positive regulation of interleukin-12 production GO:0032735 9.26 HSPD1 IFNG TLR2 TLR9
43 immune response GO:0006955 9.23 CD244 IFNG IL10 IL4 SLC11A1 TLR2
44 regulation of signaling receptor activity GO:0010469 10.06 IFNG IL10 IL4 INHA TNF
45 inflammatory response GO:0006954 10.03 IL10 SLC11A1 TLR2 TLR9 TNF

Molecular functions related to Mycobacterium Tuberculosis 1 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IFNG IL10 IL4 INHA TNF
2 signaling pattern recognition receptor activity GO:0008329 8.96 TLR2 TLR9

Sources for Mycobacterium Tuberculosis 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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