Mycobacterium Tuberculosis 1

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OMIM 57 607949 Disease Ontology 12 DOID:399 MeSH 44 D014375 D014376 SNOMED-CT 68 15202009 Orphanet 59 ORPHA3389

MESH via Orphanet 45 D014376 UMLS via Orphanet 74 C0041296 ICD10 33 A15-A19 A17.9 SNOMED-CT via HPO 69 161832001 262285001 89362005 386661006 50177009 19829001 248274002 84229001 263731006 272039006 49727002 more UMLS 73 C0041295 C0041296

MedlinePlus : ⁴³ Tuberculosis (TB) is a disease caused by bacteria called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but they can also damage other parts of the body. TB spreads through the air when a person with TB of the lungs or throat coughs, sneezes, or talks. If you have been exposed, you should go to your doctor for tests. You are more likely to get TB if you have a weak immune system. Symptoms of TB in the lungs may include A bad cough that lasts 3 weeks or longer Weight loss Loss of appetite Coughing up blood or mucus Weakness or fatigue Fever Night sweats Skin tests, blood tests, x-rays, and other tests can tell if you have TB. If not treated properly, TB can be deadly. You can usually cure active TB by taking several medicines for a long period of time. NIH: National Institute of Allergy and Infectious Diseases

MalaCards based summary : Mycobacterium Tuberculosis 1, also known as tuberculosis, is related to pleural tuberculosis and multidrug-resistant tuberculosis, and has symptoms including coughing, fever and pruritus. An important gene associated with Mycobacterium Tuberculosis 1 is CD244 (CD244 Molecule
Long noncoding RNA derived from CD244 signaling epigenetically controls CD8+ T-cell immune responses in tuberculosis infection.
Dysfunction Pattern: Regulation), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. Affiliated tissues include lungs, lymph nodes and pericardium, and related phenotypes are weight loss and fever

Disease Ontology : ¹² A primary bacterial infectious disease that is located in lungs, located in lymph nodes, located in pericardium, located in brain, located in pleura or located in gastrointestinal tract, has material basis in Mycobacterium tuberculosis, which is transmitted by droplets released into the air when an infected person coughs or sneezes.

NIH Rare Diseases : ⁵³ Tuberculosis (TB) is a contagious and often severe airborne disease caused by the TB bacterium, Mycobacterium tuberculosis. TB typically affects the lungs, but other organs of the body may be involved, as well. Not everyone who is infected with the TB bacterium becomes sick. TB bacterial infections only become "active disease" if the immune system can't stop them from growing. Classic signs and symptoms of active TB can include cough, weight loss, fever, night sweats, hemoptysis, chest pain, and fatigue. Symptoms involving areas of the body other than the lungs vary depending on which organ(s) are affected. TB is usually treated with a regimen of medications taken over a long period of time (often six to twelve months).

CDC : ³ TB Facebook

Wikipedia : ⁷⁶ Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis... more...

Description from OMIM: 607949

Clinical features from OMIM:

607949

Search NIH Clinical Center for Mycobacterium Tuberculosis 1

aminosalicylic acid antitubercular agents ethambutol ethambutol hydrochloride

ethionamide isoniazid pyrazinamide

Search GEO for disease gene expression data for Mycobacterium Tuberculosis 1.