MCID: MYC087
MIFTS: 56

Mycoplasma Pneumoniae Pneumonia

Categories: Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Mycoplasma Pneumoniae Pneumonia

MalaCards integrated aliases for Mycoplasma Pneumoniae Pneumonia:

Name: Mycoplasma Pneumoniae Pneumonia 12 15 17
Mycoplasmal Pneumonia 12 77 54
Pneumonia Due to Mycoplasma Pneumoniae 12
Cold Agglutinin Positive Pneumonia 12
Pneumonia Due to Eaton's Agent 12
Pneumonia, Mycoplasma 45
Mycoplasma Pneumonia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13276
ICD9CM 36 483.0
MeSH 45 D011019
ICD10 34 B96.0 J15.7

Summaries for Mycoplasma Pneumoniae Pneumonia

Disease Ontology : 12 A bacterial pneumonia that is caused by the bacterial species Mycoplasma pneumoniae. The symptoms include chest pain, chills, dry cough which is not bloody, excessive sweating, fever, headache and sore throat.

MalaCards based summary : Mycoplasma Pneumoniae Pneumonia, also known as mycoplasmal pneumonia, is related to myelitis and pertussis. An important gene associated with Mycoplasma Pneumoniae Pneumonia is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Azithromycin and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and heart, and related phenotypes are homeostasis/metabolism and growth/size/body region

Wikipedia : 77 Atypical pneumonia, also known as walking pneumonia, is the type of pneumonia not caused by one of the... more...

Related Diseases for Mycoplasma Pneumoniae Pneumonia

Diseases related to Mycoplasma Pneumoniae Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 574)
# Related Disease Score Top Affiliating Genes
1 myelitis 30.6 IL17A IL6 TNF
2 pertussis 30.5 IL10 IL6 TNF
3 purpura 30.5 CRP IL6 TNF
4 neuritis 30.4 IFNG IL4 TNF
5 pneumonia 30.4 CRP IL10 IL6 SFTPD TLR2 TNF
6 acute transverse myelitis 30.3 IL10 IL6
7 adult respiratory distress syndrome 30.3 IL10 IL6 TNF
8 transverse myelitis 30.3 IL10 IL17A IL6 TNF
9 haemophilus influenzae 30.2 TLR2 TNF
10 ige responsiveness, atopic 30.2 IFNG IL10 IL4
11 hemophagocytic lymphohistiocytosis 30.2 IFNG IL10 IL18 TNF
12 exanthem 30.1 CRP IL6 TNF
13 rheumatic fever 30.1 IL10 IL6 TNF
14 severe acute respiratory syndrome 30.1 CRP IFNG TNF
15 pericarditis 30.1 CRP IFNG IL6 TNF
16 acute respiratory distress syndrome 30.1 IL6 SFTPD TNF
17 allergic hypersensitivity disease 30.0 IFNG IL10 IL4
18 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 30.0 IFNG IL10 IL4
19 kawasaki disease 30.0 CRP IL10 IL6 TNF
20 cerebrovascular disease 30.0 CRP IL6 TNF
21 aseptic meningitis 29.9 IFNG IL10 TNF
22 pleurisy 29.9 CRP IFNG TNF
23 hyperlucent lung 29.8 IFNG IL10 IL4
24 heart disease 29.8 CRP IL10 IL6 TNF
25 acute pancreatitis 29.8 CRP IL10 IL18 IL6
26 rubella 29.8 IL10 IL4 TNF
27 viral pneumonia 29.8 CRP IL17A IL6
28 adult-onset still's disease 29.8 CRP IL18 IL6 TNF
29 arteries, anomalies of 29.8 CRP IL6 TNF
30 central nervous system disease 29.7 IFNG IL17A IL6 TNF
31 lichen planus 29.7 IFNG IL4 TNF
32 temporal arteritis 29.7 CRP IFNG IL6 TNF
33 rheumatic heart disease 29.7 IL10 IL4 IL6 TNF
34 polyradiculoneuropathy 29.7 IFNG IL10 IL17A
35 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 29.7 IFNG IL10 IL17A
36 nervous system disease 29.7 CRP IFNG IL10 IL6 TNF
37 respiratory failure 29.7 CRP SFTPD TNF
38 joint disorders 29.6 IL17A IL6 TNF
39 intermediate uveitis 29.6 IFNG IL10 IL6 TNF
40 dengue hemorrhagic fever 29.6 IFNG IL10 IL6 TNF
41 bronchiolitis obliterans 29.6 IFNG IL10 IL17A IL6 TNF
42 osteomyelitis 29.6 IFNG IL10 IL6 TNF
43 respiratory allergy 29.6 IL10 IL17A IL4
44 synovitis 29.6 CRP IL18 IL6 TNF
45 myasthenia gravis 29.5 IFNG IL10 IL4 TNF
46 spondylitis 29.5 CRP IL17A IL6 TNF
47 measles 29.5 IFNG IL4 IL6 TLR2
48 uveitis 29.4 IFNG IL10 IL17A IL4 TNF
49 avian influenza 29.4 IL6 SFTPD TNF
50 myocardial infarction 29.4 CRP IL10 IL6 TNF

Graphical network of the top 20 diseases related to Mycoplasma Pneumoniae Pneumonia:



Diseases related to Mycoplasma Pneumoniae Pneumonia

Symptoms & Phenotypes for Mycoplasma Pneumoniae Pneumonia

MGI Mouse Phenotypes related to Mycoplasma Pneumoniae Pneumonia:

47 (show all 16)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.18 CRP IFNG IL10 IL17A IL18 IL4
2 growth/size/body region MP:0005378 10.16 IFNG IL10 IL17A IL18 IL4 IL6
3 immune system MP:0005387 10.16 CRP IFNG IL10 IL17A IL18 IL4
4 hematopoietic system MP:0005397 10.15 IFNG IL10 IL17A IL18 IL4 IL6
5 digestive/alimentary MP:0005381 10.14 IFNG IL10 IL17A IL18 IL4 IL6
6 cardiovascular system MP:0005385 10.1 CRP IFNG IL10 IL18 IL6 TLR2
7 endocrine/exocrine gland MP:0005379 10.07 IFNG IL10 IL17A IL4 IL6 TLR2
8 mortality/aging MP:0010768 10.02 IFNG IL10 IL17A IL18 IL4 IL6
9 integument MP:0010771 9.98 IFNG IL10 IL18 IL4 IL6 TLR2
10 craniofacial MP:0005382 9.95 IFNG IL10 IL17A IL4 TNF
11 liver/biliary system MP:0005370 9.88 IFNG IL10 IL4 IL6 TLR2 TNF
12 muscle MP:0005369 9.8 IFNG IL10 IL18 IL6 TLR2 TNF
13 respiratory system MP:0005388 9.76 IFNG IL10 IL17A IL4 IL6 SFTPD
14 neoplasm MP:0002006 9.65 IFNG IL10 IL6 TLR2 TNF
15 skeleton MP:0005390 9.5 IFNG IL10 IL17A IL4 IL6 TLR2
16 vision/eye MP:0005391 9.1 IFNG IL10 IL18 IL4 IL6 TNF

Drugs & Therapeutics for Mycoplasma Pneumoniae Pneumonia

Drugs for Mycoplasma Pneumoniae Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 65)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 2,Not Applicable 83905-01-5 447043 55185
2
Methylprednisolone Approved, Vet_approved Phase 4,Not Applicable 83-43-2 6741
3
Methylprednisolone hemisuccinate Approved Phase 4,Not Applicable 2921-57-5
4
Prednisolone phosphate Approved, Vet_approved Phase 4,Not Applicable 302-25-0
5
Prednisolone Approved, Vet_approved Phase 4,Not Applicable 50-24-8 5755
6
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
7
Ofloxacin Approved Phase 4 82419-36-1 4583
8
Prednisolone hemisuccinate Experimental Phase 4,Not Applicable 2920-86-7
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
10 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
11 Anti-Inflammatory Agents Phase 4,Not Applicable
12 glucocorticoids Phase 4,Not Applicable
13 Peripheral Nervous System Agents Phase 4,Not Applicable
14 Neuroprotective Agents Phase 4,Not Applicable
15 Antiemetics Phase 4,Not Applicable
16 Antineoplastic Agents, Hormonal Phase 4,Not Applicable
17 Methylprednisolone Acetate Phase 4,Not Applicable
18 Gastrointestinal Agents Phase 4,Not Applicable
19 Hormones Phase 4,Not Applicable
20 Protective Agents Phase 4,Not Applicable
21 Prednisolone acetate Phase 4,Not Applicable
22 Autonomic Agents Phase 4,Not Applicable
23 Hormone Antagonists Phase 4,Not Applicable
24 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
25 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
26 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
27 Topoisomerase Inhibitors Phase 4,Not Applicable
28 Anti-Infective Agents, Urinary Phase 4
29 Renal Agents Phase 4
30 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
31
Ceftaroline fosamil Approved, Investigational Phase 3 229016-73-3
32
Ceftriaxone Approved Phase 3 73384-59-5 5479530 5361919
33
Clarithromycin Approved Phase 3 81103-11-9 84029
34 Cephalosporins Phase 3,Not Applicable
35 Lactams Phase 3
36 beta-Lactams Phase 3
37 Cytochrome P-450 CYP3A Inhibitors Phase 3
38 Antitubercular Agents Phase 2,Not Applicable
39
Erythromycin Approved, Investigational, Vet_approved Not Applicable 114-07-8 441411 12560
40
Doxycycline Approved, Investigational, Vet_approved Not Applicable 564-25-0 54671203
41
Cefuroxime Approved Not Applicable 55268-75-2 5479529 5361202
42
Ethinyl Estradiol Approved Not Applicable 57-63-6 5991
43
Polyestradiol phosphate Approved Not Applicable 28014-46-2
44
Estradiol Approved, Investigational, Vet_approved Not Applicable 50-28-2 5757
45
Norgestimate Approved, Investigational Not Applicable 35189-28-7 6540478
46
Moxifloxacin Approved, Investigational Not Applicable 354812-41-2, 151096-09-2 152946
47 Erythromycin Ethylsuccinate Not Applicable
48 Erythromycin stearate Not Applicable
49 Erythromycin Estolate Not Applicable
50 Antiparasitic Agents Not Applicable

Interventional clinical trials:

(show all 24)
# Name Status NCT ID Phase Drugs
1 AZithromycin Against pLacebo in Exacerbations of Asthma Completed NCT01444469 Phase 4 Zithromax;Placebo
2 Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia Recruiting NCT02618057 Phase 4 Prednisolone;Levofloxacin
3 Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Completed NCT00509106 Phase 3 Ceftaroline fosamil for Injection;Ceftriaxone;Placebo
4 Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Completed NCT00621504 Phase 3 Ceftaroline fosamil for Injection;IV Ceftriaxone;Placebo;Clarithromycin
5 Antibiotic Treatment Trial for the PANDAS/PANS Phenotype Completed NCT01617083 Phase 2 Azithromycin;Placebo
6 Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP) Unknown status NCT02303587 Not Applicable methylprednisolone
7 Prevalence and Clinical Significance of Co-infection of Mycoplasma Pneumoniae in Patients With Pulmonary Tuberculosis Unknown status NCT00926601
8 Etiology Study of Kawasaki Disease Unknown status NCT00154596
9 Effectiveness Study of Integrative Treatment for Pediatric Community Acquired Pneumonia Unknown status NCT02362906 Not Applicable Xiyanping injection;wind-heat formula granules;phlegm-heat formula granules;Fu-xiong San;second generation cephalosporin;Erythromycin;Azithromycin
10 Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting Completed NCT00207584 Not Applicable Doxycycline treatment
11 Detection of Mycoplasma Pneumoniae Completed NCT02511262
12 Evaluation of Pathogenesis and Diagnosis of Mycoplasma Pneumoniae Community-acquired Pneumonia (CAP) Completed NCT03613636
13 The Optimization of Mycoplasm Pneumonia Antibiotic Therapy Completed NCT01259141 Not Applicable Moxifloxacin;Cephalosporins and azithromycin
14 Chlamydia and Mycoplasma in Coronary Artery Disease Completed NCT00561028
15 Etiology of Community Acquired Pneumonia Completed NCT00471757
16 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
17 A Molecular Toolkit for the Microbial Investigation of Severe Community Acquired Pneumonia Completed NCT02963142
18 Treatment and Vaccine Development of Mycoplasma Pneumoniae Recruiting NCT03911440 Not Applicable Doxycycline;Azithromycin
19 Treatment of Macrolide-resistant Mycoplasma Pneumoniae Recruiting NCT03530319 Not Applicable Doxycycline;Azithromycin
20 Assessment of Pharyngeal Carriage of Microorganisms Responsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims. Recruiting NCT02868541
21 DiagNostic Study of Low-dose CT and multipleX PCR on Antibiotic Treatment and Outcome of Community-Acquired Pneumonia Recruiting NCT03360851 Not Applicable
22 Comparative Autoantibody and Immunologic Cell Marker Study Enrolling by invitation NCT02422875
23 Methylprednisolone Pulse Macrolide Therapy for Refractory Mycoplasma Pneumoniae Pneumonia in Children Terminated NCT01217099 Not Applicable methylprednisolone;azithromycin
24 Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For CAP Withdrawn NCT01662258 Not Applicable

Search NIH Clinical Center for Mycoplasma Pneumoniae Pneumonia

Cochrane evidence based reviews: pneumonia, mycoplasma

Genetic Tests for Mycoplasma Pneumoniae Pneumonia

Anatomical Context for Mycoplasma Pneumoniae Pneumonia

MalaCards organs/tissues related to Mycoplasma Pneumoniae Pneumonia:

42
Lung, T Cells, Heart, Testes, Skin, Bone, Eye

Publications for Mycoplasma Pneumoniae Pneumonia

Articles related to Mycoplasma Pneumoniae Pneumonia:

(show top 50) (show all 324)
# Title Authors Year
1
Plasma soluble B7-H3 levels for severity evaluation in pediatric patients with Mycoplasma pneumoniae pneumonia. ( 31100711 )
2019
2
The role of miR-29c/B7-H3/Th17 axis in children with Mycoplasma pneumoniae pneumonia. ( 31088519 )
2019
3
Benefits and risks of therapeutic alternatives for macrolide resistant Mycoplasma Pneumoniae pneumonia in children. ( 30999732 )
2019
4
Epidemiological relationship between Mycoplasma pneumoniae pneumonia and recurrent wheezing episode in children: an observational study at a single hospital in Korea. ( 30975681 )
2019
5
Impact of atopy on the severity and extrapulmonary manifestations of childhood Mycoplasma pneumoniae pneumonia. ( 30924557 )
2019
6
An adult case of severe life-threatening Mycoplasma pneumoniae pneumonia due to a macrolide-resistant strain, Japan: a case report. ( 30819124 )
2019
7
Comparison of high-dose and low-dose corticosteroid therapy for refractory Mycoplasma pneumoniae pneumonia in children. ( 30718192 )
2019
8
Clinical Characteristics and Antibiotic Resistance of Mycoplasma Pneumoniae Pneumonia in Hospitalized Chinese Children. ( 30636596 )
2019
9
A 6-year-old girl with severe, focal Mycoplasma pneumoniae pneumonia. ( 30066973 )
2019
10
Rapid resolution of reversible bronchiectasis after Mycoplasma pneumoniae pneumonia in an adult: A case report. ( 30921231 )
2019
11
Clinical features of Mycoplasma pneumoniae pneumonia in older adults. ( 29722163 )
2018
12
Reply to 'Influenza follicles and their buds as early diagnostic markers of influenza: typical images' and demonstration of lymphoid follicles in the posterior pharyngeal walls of patients with mycoplasmal pneumonia. ( 29440479 )
2018
13
Role of Probiotics in Mycoplasma pneumoniae Pneumonia in Children: A Short-Term Pilot Project. ( 30687259 )
2018
14
Independent predictors for longer radiographic resolution in patients with refractory Mycoplasma pneumoniae pneumonia: a prospective cohort study. ( 30567824 )
2018
15
Assessment of levels of D-dimer and interferon-γ in pediatric patients with Mycoplasma pneumoniae pneumonia and its clinical implication. ( 30546408 )
2018
16
Mycoplasma Pneumoniae Pneumonia: Walking Pneumonia Can Cripple the Susceptible. ( 30425761 )
2018
17
Low Bacterial Co-infection Invalidates the Early Use of Non-anti-Mycoplasma pneumoniae Antibiotics in Pediatric Refractory Mycoplasma pneumoniae Pneumonia Patients. ( 30416990 )
2018
18
Therapeutic Efficacy and Safety of Prolonged Macrolide, Corticosteroid, Doxycycline, and Levofloxacin against Macrolide-Unresponsive Mycoplasma pneumoniae Pneumonia in Children. ( 30344461 )
2018
19
Ameliorative Effects of Infantile Feire Kechuan Oral Solution on Mycoplasma Pneumoniae Pneumonia in Infant Mouse and Rat Models. ( 30305831 )
2018
20
Serum Tumor Necrosis Factor-α and Interferon-γ Levels in Pediatric Mycoplasma pneumoniae Pneumonia: A Systematic Review and Meta-Analysis. ( 30275916 )
2018
21
Mycoplasma pneumoniae Pneumonia with Worsening Pleural Effusion Despite Treatment with Appropriate Antimicrobials: Case report. ( 30210860 )
2018
22
Clinical effect of sequential therapy with azithromycin in children mycoplasma pneumoniae pneumonia. ( 30203754 )
2018
23
High expression of HMGB1 in children with refractory Mycoplasma pneumoniae pneumonia. ( 30157804 )
2018
24
The role of granulocyte macrophage colony stimulating factor in hospitalized children with Mycoplasma pneumoniae pneumonia. ( 30007865 )
2018
25
Viral and bacterial co-infection in hospitalised children with refractory Mycoplasma pneumoniae pneumonia. ( 29970200 )
2018
26
Transcriptome Analysis of Bronchoalveolar Lavage Fluid From Children With Mycoplasma pneumoniae Pneumonia Reveals Natural Killer and T Cell-Proliferation Responses. ( 29967623 )
2018
27
The concordance between upper and lower respiratory microbiota in children with Mycoplasma pneumoniae pneumonia. ( 29789582 )
2018
28
Refractory Mycoplasma pneumoniae pneumonia with concomitant acute cerebral infarction in a child: A case report and literature review. ( 29595632 )
2018
29
The timing of azithromycin treatment is not associated with the clinical prognosis of childhood Mycoplasma pneumoniae pneumonia in high macrolide-resistant prevalence settings. ( 29377957 )
2018
30
Serum lactate dehydrogenase isoenzymes 4 plus 5 is a better biomarker than total lactate dehydrogenase for refractory Mycoplasma pneumoniae pneumonia in children. ( 29337082 )
2018
31
Antimicrobial therapy of macrolide-resistant Mycoplasma pneumoniae pneumonia in children. ( 29212389 )
2018
32
Leukoagglutination, Mycoplasma pneumoniae Pneumonia, and EDTA Acid Blood. ( 29192604 )
2018
33
Contribution of Co-detected Respiratory Viruses and Patient Age to the Clinical Manifestations of Mycoplasma Pneumoniae Pneumonia in Children. ( 29095244 )
2018
34
Wanted: The Best Second Option to Treat Macrolide-Unresponsive Mycoplasmal Pneumonia in Children. ( 30344464 )
2018
35
Effects of mycoplasmal pneumonia of swine (MPS) lung lesion-selected Landrace pigs on MPS resistance and immune competence in three-way crossbred pigs. ( 27612216 )
2017
36
Determinants for swine mycoplasmal pneumonia reproduction under experimental conditions: A systematic review and recursive partitioning analysis. ( 28742802 )
2017
37
Prediction of Bronchial Mucus Plugs Formation in Patients with Refractory Mycoplasma Pneumoniae Pneumonia. ( 27686558 )
2017
38
Role of E-selectin for diagnosing myocardial injury in paediatric patients with mycoplasma pneumoniae pneumonia. ( 26843511 )
2017
39
Atopy: a risk factor of refractory mycoplasma pneumoniae pneumonia? ( 26683420 )
2017
40
Overview of antimicrobial options for Mycoplasma pneumoniae pneumonia: focus on macrolide resistance. ( 26365811 )
2017
41
Sequential Mycoplasma pneumoniae pneumonia and Chromobacterium violaceum skin abscess in a pediatric patient. ( 31085828 )
2017
42
The early examination of combined serum and imaging data under flexible fiberoptic bronchoscopy as a novel predictor for refractory Mycoplasma pneumoniae pneumonia diagnosis. ( 29390413 )
2017
43
A Case of Macrolide-Refractory Mycoplasma pneumoniae Pneumonia in Pregnancy Treated with Garenoxacin. ( 29375919 )
2017
44
Adjunctive corticosteroid therapy for inpatients with Mycoplasma pneumoniae pneumonia. ( 29284447 )
2017
45
Additional corticosteroids or alternative antibiotics for the treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia. ( 29042865 )
2017
46
Interleukin 17A as a good predictor of the severity of Mycoplasma pneumoniae pneumonia in children. ( 29021577 )
2017
47
Comparison of Efficacy of Antimicrobial Agents Among Hospitalized Patients With Mycoplasma pneumoniae Pneumonia in Japan During Large Epidemics of Macrolide-Resistant M. pneumoniae Infections: A Nationwide Observational Study. ( 29020161 )
2017
48
The Correlation between Chest X-ray Scores and the Clinical Findings in Children and Adults with Mycoplasma pneumoniae Pneumonia. ( 28943541 )
2017
49
Unexplained Dyspnea in a Young Adult with Epstein-Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia? ( 28869530 )
2017
50
Effect of Qingfei Mixture () on pediatric mycoplasma pneumoniae pneumonia with phlegm heat obstructing Fei (Lung) syndrome. ( 28861888 )
2017

Variations for Mycoplasma Pneumoniae Pneumonia

Expression for Mycoplasma Pneumoniae Pneumonia

Search GEO for disease gene expression data for Mycoplasma Pneumoniae Pneumonia.

Pathways for Mycoplasma Pneumoniae Pneumonia

Pathways related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.93 CRP IFNG IL10 IL17A IL18 IL4
2
Show member pathways
13.6 IFNG IL10 IL17A IL18 IL4 IL6
3
Show member pathways
13.48 IFNG IL10 IL17A IL18 IL4 IL6
4
Show member pathways
13.36 IL10 IL17A IL18 IL4 IL6 TLR2
5
Show member pathways
13.31 IFNG IL10 IL17A IL18 IL4 IL6
6
Show member pathways
13.24 IL10 IL17A IL18 IL4 IL6 TNF
7
Show member pathways
13.1 IFNG IL10 IL18 IL6 SFTPD TLR2
8
Show member pathways
12.88 IFNG IL10 IL17A IL18 IL4 IL6
9
Show member pathways
12.69 IFNG IL18 IL6 TNF
10
Show member pathways
12.63 IFNG IL10 IL18 IL4 TNF
11
Show member pathways
12.62 IFNG IL10 IL17A IL18 IL6 TNF
12 12.6 IFNG IL10 IL17A IL4 TLR2 TNF
13
Show member pathways
12.59 IFNG IL10 IL17A IL4 IL6 TNF
14
Show member pathways
12.46 IFNG IL10 IL17A IL18 IL4 IL6
15
Show member pathways
12.38 IFNG IL10 IL4 IL6
16
Show member pathways
12.37 CRP IFNG IL4 IL6 TNF
17
Show member pathways
12.37 IFNG IL17A IL4 IL6 TLR2 TNF
18
Show member pathways
12.31 IFNG IL10 IL4 TLR2 TNF
19 12.27 IFNG IL10 IL18 IL6 TLR2 TNF
20
Show member pathways
12.26 IFNG IL10 IL17A IL18 IL4 IL6
21
Show member pathways
12.23 IL18 IL6 TLR2 TNF
22
Show member pathways
12.22 IFNG IL4 IL6 SFTPD TLR2 TNF
23 12.2 IFNG IL6 TLR2 TNF
24
Show member pathways
12.19 IL6 TLR2 TNF
25
Show member pathways
12.15 IL10 IL6 TNF
26 12.12 IL10 IL6 TNF
27
Show member pathways
12.11 IFNG IL10 IL17A IL18 IL4 IL6
28
Show member pathways
12.1 IFNG IL4 IL6 TLR2 TNF
29 12.05 IFNG IL10 IL4 IL6 TNF
30 12.04 IFNG IL4 IL6 TNF
31 12.01 IL10 IL17A IL18 IL4 IL6 TNF
32
Show member pathways
11.95 IFNG IL18 IL4
33 11.95 IFNG IL10 IL6 TLR2 TNF
34
Show member pathways
11.91 IFNG IL10 IL17A IL18 IL6 TLR2
35 11.88 IL4 IL6 TNF
36 11.84 IFNG IL10 IL6
37 11.84 IFNG IL17A IL18 IL6 TLR2 TNF
38 11.83 IFNG IL18 IL6
39 11.82 IFNG IL10 IL6 TNF
40 11.81 IFNG IL4 IL6
41
Show member pathways
11.77 IFNG IL4 TNF
42 11.76 IL10 IL6 TNF
43 11.75 IFNG IL10 IL17A IL18 IL4 TNF
44 11.68 IL4 IL6 TNF
45
Show member pathways
11.68 IFNG IL6 TNF
46 11.67 IL18 IL6 TLR2 TNF
47 11.61 IFNG IL18 TLR2 TNF
48 11.58 IFNG IL6 TNF
49 11.58 IL10 IL18 IL4 IL6 TNF
50 11.53 IFNG IL10 IL4

GO Terms for Mycoplasma Pneumoniae Pneumonia

Cellular components related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CRP IFNG IL10 IL17A IL18 IL4
2 extracellular space GO:0005615 9.28 CRP IFNG IL10 IL17A IL18 IL4

Biological processes related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

(show all 45)
# Name GO ID Score Top Affiliating Genes
1 cellular response to lipopolysaccharide GO:0071222 9.85 IL10 IL6 TNF
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.84 IL18 IL6 TLR2 TNF
3 positive regulation of DNA-binding transcription factor activity GO:0051091 9.82 IL10 IL6 TNF
4 positive regulation of inflammatory response GO:0050729 9.81 IL18 TLR2 TNF
5 response to glucocorticoid GO:0051384 9.8 IL10 IL6 TNF
6 defense response to Gram-positive bacterium GO:0050830 9.8 CRP IL6 TLR2 TNF
7 cytokine-mediated signaling pathway GO:0019221 9.8 IL10 IL17A IL18 IL4 IL6 TNF
8 regulation of signaling receptor activity GO:0010469 9.8 IFNG IL10 IL17A IL18 IL4 IL6
9 positive regulation of interleukin-6 production GO:0032755 9.79 IL6 TLR2 TNF
10 humoral immune response GO:0006959 9.78 IFNG IL6 TNF
11 positive regulation of smooth muscle cell proliferation GO:0048661 9.77 IL18 IL6 TNF
12 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.76 IL18 TLR2 TNF
13 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.76 IFNG IL18 IL4 IL6
14 lipopolysaccharide-mediated signaling pathway GO:0031663 9.73 IL18 TLR2 TNF
15 negative regulation of interleukin-6 production GO:0032715 9.7 IL10 TNF
16 positive regulation of osteoclast differentiation GO:0045672 9.7 IFNG IL17A TNF
17 positive regulation of gene expression GO:0010628 9.7 CRP IFNG IL18 IL4 IL6 TLR2
18 positive regulation of cytokine secretion GO:0050715 9.69 IL10 TNF
19 positive regulation of interleukin-8 production GO:0032757 9.69 TLR2 TNF
20 regulation of synapse organization GO:0050807 9.69 IL10 TNF
21 positive regulation of chemokine production GO:0032722 9.69 IL6 TLR2 TNF
22 negative regulation of myoblast differentiation GO:0045662 9.68 IL18 TNF
23 negative regulation of neurogenesis GO:0050768 9.68 IL6 TNF
24 positive regulation of interleukin-12 production GO:0032735 9.68 IFNG TLR2
25 positive regulation of protein complex assembly GO:0031334 9.68 IFNG TNF
26 microglial cell activation GO:0001774 9.67 TLR2 TNF
27 positive regulation of glial cell proliferation GO:0060252 9.67 IL6 TNF
28 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.66 IFNG TNF
29 negative regulation of growth of symbiont in host GO:0044130 9.66 IL10 TNF
30 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.65 IL10 TNF
31 response to molecule of bacterial origin GO:0002237 9.65 IL10 TLR2
32 endothelial cell apoptotic process GO:0072577 9.64 IL10 TNF
33 positive regulation of MHC class II biosynthetic process GO:0045348 9.63 IL10 IL4
34 negative regulation of cytokine secretion involved in immune response GO:0002740 9.63 IL10 TNF
35 positive regulation of interleukin-23 production GO:0032747 9.62 IFNG IL17A
36 negative regulation of lipid storage GO:0010888 9.61 CRP IL6 TNF
37 regulation of isotype switching GO:0045191 9.59 IL10 IL4
38 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.58 IFNG TNF
39 positive regulation of neuroinflammatory response GO:0150078 9.58 IL18 IL6 TNF
40 receptor biosynthetic process GO:0032800 9.57 IL10 TNF
41 positive regulation of vitamin D biosynthetic process GO:0060557 9.55 IFNG TNF
42 type 2 immune response GO:0042092 9.54 IL10 IL18 IL4
43 inflammatory response GO:0006954 9.5 CRP IL10 IL17A IL18 IL6 TLR2
44 immune response GO:0006955 9.23 IFNG IL10 IL17A IL18 IL4 IL6
45 positive regulation of transcription by RNA polymerase II GO:0045944 10.02 IL10 IL17A IL18 IL4 IL6 TLR2

Molecular functions related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.85 CRP IFNG IL10 IL17A IL18 IL4
2 cytokine activity GO:0005125 9.17 IFNG IL10 IL17A IL18 IL4 IL6
3 growth factor activity GO:0008083 9.13 IL10 IL4 IL6

Sources for Mycoplasma Pneumoniae Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
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31 HGMD
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