MCID: MYC087
MIFTS: 52

Mycoplasma Pneumoniae Pneumonia

Categories: Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Mycoplasma Pneumoniae Pneumonia

MalaCards integrated aliases for Mycoplasma Pneumoniae Pneumonia:

Name: Mycoplasma Pneumoniae Pneumonia 12 15 17
Mycoplasmal Pneumonia 12 73 20
Pneumonia Due to Mycoplasma Pneumoniae 12 32
Mycoplasma Pneumonia 12 70
Cold Agglutinin Positive Pneumonia 12
Pneumonia Due to Eaton's Agent 12
Pneumonia, Mycoplasma 44

Classifications:



External Ids:

Disease Ontology 12 DOID:13276
ICD9CM 34 483.0
MeSH 44 D011019
ICD10 32 B96.0 J15.7
UMLS 70 C0032302

Summaries for Mycoplasma Pneumoniae Pneumonia

Disease Ontology : 12 A bacterial pneumonia that is caused by the bacterial species Mycoplasma pneumoniae. The symptoms include chest pain, chills, dry cough which is not bloody, excessive sweating, fever, headache and sore throat.

MalaCards based summary : Mycoplasma Pneumoniae Pneumonia, also known as mycoplasmal pneumonia, is related to haemophilus influenzae and lymphopenia. An important gene associated with Mycoplasma Pneumoniae Pneumonia is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Ofloxacin and Levofloxacin have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and skin, and related phenotypes are hematopoietic system and immune system

Wikipedia : 73 Atypical pneumonia, also known as walking pneumonia, is any type of pneumonia not caused by one of the... more...

Related Diseases for Mycoplasma Pneumoniae Pneumonia

Diseases related to Mycoplasma Pneumoniae Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 864)
# Related Disease Score Top Affiliating Genes
1 haemophilus influenzae 30.8 TNF TLR2
2 lymphopenia 30.6 IL6 IL4 IL10 IFNG
3 cold agglutinin disease 30.5 IL6 CRP
4 bronchopneumonia 30.5 TNF IL6 IL17A IL10 F3 CRP
5 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 30.5 IL17A IL10 IFNG
6 erythema multiforme 30.5 TNF IL6 IL4 IFNG
7 encephalitis 30.5 TNF TLR2 IL6 IL10
8 tendinitis 30.5 TNF IL6 CRP
9 ige responsiveness, atopic 30.5 IL4 IL13 IL10 IFNG
10 chlamydia pneumonia 30.4 TNF TLR2 IL6 IL4 IL10 CRP
11 lemierre's syndrome 30.4 F3 CRP
12 pharyngitis 30.4 TNF IL6 CSF2 CRP
13 pulmonary embolism 30.4 F3 CRP ACE
14 myelitis 30.4 TNF IL6 IL17A IL10
15 erysipelas 30.3 TNF IL6 CRP
16 arthropathy 30.3 TNF IL6 IFNG CRP
17 hemophagocytic lymphohistiocytosis 30.3 TNF IL18 IL10 IFNG
18 uveitis 30.3 TNF IL6 IL4 IL17A IL10 IFNG
19 transverse myelitis 30.3 TNF IL6 IL17A IL10
20 lung abscess 30.3 TNF IL6 IFNG CRP
21 acute pancreatitis 30.3 TNF IL6 IL18 IL10 CRP
22 meningoencephalitis 30.3 TNF IL6 IL10 CRP
23 hemolytic anemia 30.3 TNF IL4 IL17A IL10 IFNG F3
24 measles 30.3 TNF TLR2 IL6 IFNG
25 optic nerve disease 30.3 TNF IL6 IL17A CRP
26 septic arthritis 30.3 TNF TLR2 IFNG CRP
27 facial paralysis 30.3 TNF CRP ACE
28 myositis 30.2 TNF IL6 IL17A IFNG
29 thrombocytosis 30.2 IL6 F3 CSF2 CRP
30 capillary leak syndrome 30.2 IL6 CSF2 C3
31 dysentery 30.2 TNF IL6 IL10 CRP
32 bronchitis 30.2 TNF TLR2 IL6 IL4 IL13 IL10
33 fibromyalgia 30.2 TNF IL6 IL10 CRP
34 epidemic typhus 30.2 TNF IL10 CRP
35 rhinitis 30.2 TNF IL6 IL4 IL17A IL13 IL10
36 lymphadenitis 30.1 TNF IL18 IL10 IFNG CRP
37 iridocyclitis 30.1 TNF IL6 IL17A IL10 CRP ACE
38 adult respiratory distress syndrome 30.1 TNF SFTPD IL6 IL10 ACE
39 chronic granulomatous disease 30.1 TNF IL18 IL17A IFNG CSF2
40 spondyloarthropathy 1 30.1 TNF IL6 IL17A CRP
41 viral pneumonia 30.0 TNF SFTPD IL6 IL17A IL10 CRP
42 disseminated intravascular coagulation 30.0 TNF IL6 IL10 F3 CRP
43 kawasaki disease 30.0 TNF IL6 IL4 IL18 IL17A IL10
44 allergic bronchopulmonary aspergillosis 30.0 SFTPD IL4 IL10 IFNG
45 cholera 30.0 TNF IL6 IL4 IL10
46 severe acute respiratory syndrome 29.9 TNF IL6 IL10 IFNG CRP ACE
47 bacterial pneumonia 29.9 TNF TLR2 SFTPD IL6 IL17A IL10
48 neuromyelitis optica 29.9 IL6 IL4 IL17A C3
49 central nervous system disease 29.9 TNF IL6 IL17A IFNG
50 hypereosinophilic syndrome 29.9 IL4 IL13 IL10 IFNG CSF2

Comorbidity relations with Mycoplasma Pneumoniae Pneumonia via Phenotypic Disease Network (PDN):


Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Respiratory Failure

Graphical network of the top 20 diseases related to Mycoplasma Pneumoniae Pneumonia:



Diseases related to Mycoplasma Pneumoniae Pneumonia

Symptoms & Phenotypes for Mycoplasma Pneumoniae Pneumonia

MGI Mouse Phenotypes related to Mycoplasma Pneumoniae Pneumonia:

46 (show all 19)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.47 ACE C3 CD276 CSF2 CYP1A1 F3
2 immune system MP:0005387 10.46 ACE C3 CD276 CRP CSF2 CYP1A1
3 homeostasis/metabolism MP:0005376 10.45 ACE C3 CRP CSF2 CYP1A1 F3
4 growth/size/body region MP:0005378 10.42 ACE C3 CSF2 CYP1A1 F3 IFNG
5 mortality/aging MP:0010768 10.36 ACE C3 CSF2 CYP1A1 F3 IFNG
6 endocrine/exocrine gland MP:0005379 10.34 ACE C3 CSF2 CYP1A1 IFNG IL10
7 cardiovascular system MP:0005385 10.32 ACE C3 CRP CSF2 F3 IFNG
8 cellular MP:0005384 10.32 C3 CSF2 F3 IFNG IL10 IL13
9 digestive/alimentary MP:0005381 10.31 C3 IFNG IL10 IL13 IL17A IL18
10 integument MP:0010771 10.27 CSF2 F3 IFNG IL10 IL13 IL17A
11 nervous system MP:0003631 10.15 ACE C3 CSF2 F3 IFNG IL10
12 liver/biliary system MP:0005370 10.13 ACE C3 CYP1A1 IFNG IL10 IL4
13 muscle MP:0005369 10.09 C3 F3 IFNG IL10 IL13 IL18
14 neoplasm MP:0002006 10.06 ACE CSF2 F3 IFNG IL10 IL23A
15 no phenotypic analysis MP:0003012 9.92 CYP1A1 IFNG IL10 IL13 IL17A IL23A
16 respiratory system MP:0005388 9.9 CSF2 F3 IFNG IL10 IL13 IL17A
17 renal/urinary system MP:0005367 9.86 ACE C3 CSF2 IFNG IL17A IL4
18 skeleton MP:0005390 9.7 C3 CD276 CSF2 IFNG IL10 IL13
19 vision/eye MP:0005391 9.28 ACE C3 F3 IFNG IL10 IL18

Drugs & Therapeutics for Mycoplasma Pneumoniae Pneumonia

Drugs for Mycoplasma Pneumoniae Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 38)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ofloxacin Approved Phase 4 82419-36-1 4583
2
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
3 Cytochrome P-450 Enzyme Inhibitors Phase 4
4
Methylprednisolone Approved, Vet_approved 83-43-2 6741
5
Methylprednisolone hemisuccinate Approved 2921-57-5
6
Prednisolone Approved, Vet_approved 50-24-8 5755
7
Prednisolone acetate Approved, Vet_approved 52-21-1
8
Prednisolone phosphate Approved, Vet_approved 302-25-0
9
Cefuroxime Approved 55268-75-2 5361202 5479529
10
Moxifloxacin Approved, Investigational 151096-09-2, 354812-41-2 152946
11
Doxycycline Approved, Investigational, Vet_approved 564-25-0 54671203
12
Betamethasone Approved, Vet_approved 378-44-9 9782
13
Tetracycline Approved, Vet_approved 60-54-8 5353990
14
Azithromycin Approved 83905-01-5 55185 447043
15
Prednisolone hemisuccinate Experimental 2920-86-7
16 Hormones
17 Methylprednisolone Acetate
18 Hormone Antagonists
19 Anti-Inflammatory Agents
20 glucocorticoids
21 Antineoplastic Agents, Hormonal
22 Cephalosporins
23 cefuroxime axetil
24 Norgestimate, ethinyl estradiol drug combination
25 Antiparasitic Agents
26 Antimalarials
27 Antiprotozoal Agents
28 Vaccines
29 Immunologic Factors
30 Anti-Bacterial Agents
31 Anti-Infective Agents
32 Antibiotics, Antitubercular
33 Immunoglobulins
34 Antibodies
35 Gastrointestinal Agents
36 Antiemetics
37 Neuroprotective Agents
38 Protective Agents

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia With Lobar Consolidation or Pleural Effusion in Children Unknown status NCT02618057 Phase 4 Prednisolone;Levofloxacin
2 Prevalence and Clinical Significance of Co-infection of Mycoplasma Pneumoniae in Patients With Pulmonary Tuberculosis Unknown status NCT00926601
3 Low Dose Versus High Dose Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia : a Multicenter Randomized Blinded Trial Completed NCT02303587 methylprednisolone
4 The Optimization of Mycoplasm Pneumonia Antibiotic Therapy: Multi-centre, Prospective, Randomized Controlled Study Completed NCT01259141 Moxifloxacin;Cephalosporins and azithromycin
5 Clinical Trial Protocol for the Illumigene® Mycoplasma Direct Assay Completed NCT02511262
6 A Double-Blind, Randomized Placebo-Controlled Trial of Doxycycline for Chemoprophylaxis in the Setting of an Outbreak of Mycoplasma Pneumoniae Completed NCT00207584 Doxycycline treatment
7 The Role of Adaptive Immune Responses to Mycoplasma Pneumoniae in Pathogenesis and Diagnosis of Community-acquired Pneumonia (CAP) in Children: an Observational Single-center Study (myCAP Study) Completed NCT03613636
8 Prevalence of Chlamydia Pneumoniae and Mycoplasma Pneumoniae in Different Forms of Obstructive Coronary Artery Disease Completed NCT00561028
9 Etiology of Community Acquired Pneumonia Completed NCT00471757
10 Studies on Macrolide-resistant Mycoplasma Pneumoniae in Taiwan- A Randomized Control Trial and MLVA Analysis Recruiting NCT03530319 Doxycycline;Azithromycin
11 Diagnosis and Treatment of Mycoplasma Pneumoniae and Vaccine Development Recruiting NCT03911440 Doxycycline;Azithromycin
12 Diagnosis of Mycoplasma Pneumoniae Infection With Detection of Specific Antibody-secreting Cells in Community-acquired Pneumonia (CAP) Patients of the Randomised Placebo-controlled Multi-centre Effectiveness Trial of Adjunct Betamethasone Therapy (myKIDS-STEP) Recruiting NCT04043325
13 A Randomized, Double-blind, Parallel-controlled,Multicenter Clinical Study of Xiyanping Injection Combined With Azithromycin and Azithromycin for Children With Pneumonia Not yet recruiting NCT04296383 Azithromycin plus Xiyanping injection;Azithromycin
14 Multi-center Investigation and Study of Mycoplasma Pneumoniae Infection and Macrolide Drug Resistance in Outpatient and In-hospital Pediatric Acute Respiratory Diseases Illness in China Not yet recruiting NCT04126304 Azithromycin;non-macrolides antibiotics
15 A Prospective, Open-label Trial of Methylprednisolone Pulse Macrolide Therapy for Refractory Mycoplasma Pneumoniae Pneumonia in Children Terminated NCT01217099 methylprednisolone;azithromycin

Search NIH Clinical Center for Mycoplasma Pneumoniae Pneumonia

Cochrane evidence based reviews: pneumonia, mycoplasma

Genetic Tests for Mycoplasma Pneumoniae Pneumonia

Anatomical Context for Mycoplasma Pneumoniae Pneumonia

MalaCards organs/tissues related to Mycoplasma Pneumoniae Pneumonia:

40
Heart, Lung, Skin, Bone, Kidney, Liver, Eye

Publications for Mycoplasma Pneumoniae Pneumonia

Articles related to Mycoplasma Pneumoniae Pneumonia:

(show top 50) (show all 756)
# Title Authors PMID Year
1
Long non‑coding RNA GAS5 protects against Mycoplasma pneumoniae pneumonia by regulating the microRNA‑222‑3p/TIMP3 axis. 61
33760178 2021
2
Expression of Concern: miR-143-3p impacts on pulmonary inflammatory factors and cell apoptosis in mice with mycoplasmal pneumonia by regulating TLR4/MyD88/NF-κB pathway. 61
33786576 2021
3
Macrolide-Resistant and Macrolide-Sensitive Mycoplasma pneumoniae Pneumonia in Children Treated Using Early Corticosteroids. 61
33810090 2021
4
Development of a scale for early prediction of refractory Mycoplasma pneumoniae pneumonia in hospitalized children. 61
33758243 2021
5
Predictive Factors of the Responses to Treatment of Mycoplasma pneumoniae Pneumonia. 61
33801856 2021
6
The risk factors of children acquiring refractory mycoplasma pneumoniae pneumonia: A meta-analysis. 61
33725960 2021
7
Correlations between Serum P2X7, Vitamin A, 25-hydroxy Vitamin D, and Mycoplasma Pneumoniae Pneumonia. 61
33724522 2021
8
The combination of initial markers to predict refractory Mycoplasma pneumoniae pneumonia in Chinese children: a case control study. 61
33752670 2021
9
Mycoplasma pneumoniae pneumonia with pulmonary embolism: A study on pediatric cases in Jilin province of China. 61
33574906 2021
10
Characteristics and Outcome of Severe Mycoplasma pneumoniae Pneumonia Admitted to PICU in Shanghai: A Retrospective Cohort Study. 61
33786442 2021
11
Cardiac thrombus and stroke in a child with Mycoplasma pneumoniae pneumonia: A case report. 61
33592875 2021
12
Prevalence and clinical characteristics of hospitalized children with community-acquired Mycoplasma pneumoniae pneumonia during 2017/2018, Chengde, China. 61
33592835 2021
13
Consideration in treatment decisions for refractory Mycoplasma pneumoniae pneumonia. 61
33561337 2021
14
Clinical Efficacy of Doxycycline for Treatment of Macrolide-Resistant Mycoplasma pneumoniae Pneumonia in Children. 61
33671151 2021
15
Cases of macrolide-resistant Mycoplasma pneumoniae pneumonia-associated pulmonary thromboembolism. 61
33559952 2021
16
The clinical characteristics of Mycoplasma pneumoniae pneumonia and its relationship between hypokalemia in west China. 61
33708527 2021
17
The effect of vibrating positive expiratory pressure therapy on refractory Mycoplasma pneumoniae pneumonia prognosis in children. 61
33708517 2021
18
Comparison of different detection methods for Mycoplasma pneumoniae infection in children with community-acquired pneumonia. 61
33607971 2021
19
A comparison of efficacy and safety of complementary and alternative therapies for severe mycoplasma pneumonia in children: A protocol for systematic review and meta-analysis. 61
33607763 2021
20
Prediction of risk factors of bronchial mucus plugs in children with Mycoplasma pneumoniae pneumonia. 61
33441105 2021
21
Time to Mycoplasma Pneumoniae RNA Clearance for Wheezy vs. Non-Wheezy Young Children with Community-Acquired Pneumonia. 61
33274390 2021
22
Clinical observation of aerosol inhalation of azithromycin combined with budesonide suspension in the treatment of mycoplasma pneumoniae pneumonia in children. 61
33496157 2021
23
Mycoplasma pneumoniae pneumonia and respiratory syncytial virus infection in Japan during the severe acute respiratory syndrome coronavirus 2 pandemic. 61
33279448 2021
24
Clinical characteristics of refractory mycoplasma pneumoniae pneumonia in children treated with glucocorticoid pulse therapy. 61
33509121 2021
25
[Focus on the difficulties and challenges in the diagnosis and treatment of Mycoplasma pneumoniae pneumonia]. 61
33412618 2021
26
Clinical significance of D-dimer levels in refractory Mycoplasma pneumoniae pneumonia. 61
33407216 2021
27
Severe Mycoplasma pneumoniae pneumonia requiring intensive care in children, 2010-2019. 61
32948415 2021
28
Proteomic and mechanistic study of Qingxuan Tongluo formula and curcumin in the treatment of Mycoplasma pneumoniae pneumonia. 61
33378995 2021
29
[Clinical features of children with Mycoplasma pneumoniae pneumonia and peripheral lymphocytopenia]. 61
33476541 2021
30
The relationships between LncRNA NNT-AS1, CRP, PCT and their interactions and the refractory mycoplasma pneumoniae pneumonia in children. 61
33479472 2021
31
Diagnostic Value of Serum ELISA of Mycoplasma Pneumoniae IgM and IgG and Passive Particle Agglutination for Mycoplasma Pneumoniae Pneumonia in Children. 61
33491435 2021
32
Evaluation on blood coagulation and C-reactive protein level among children with mycoplasma pneumoniae pneumonia by different chest imaging findings. 61
33545964 2021
33
Skin and Mucous Membrane Eruptions Associated with Chlamydophila Pneumoniae Respiratory Infections: Literature Review. 61
32222707 2021
34
The treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children. 61
33403672 2021
35
Clinically mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with Mycoplasma pneumoniae pneumonia: An adult case and review of the literature. 61
33363858 2020
36
Risk factors for the development of post-infectious bronchiolitis obliterans after Mycoplasma pneumoniae pneumonia in the era of increasing macrolide resistance. 61
33186845 2020
37
Comparative efficacy and safety of traditional Chinese patent medicine in the treatment of Mycoplasma pneumoniae pneumonia in children: A protocol for systematic review and meta-analysis. 61
33371133 2020
38
The critical function of miR-1323/Il6 axis in children with Mycoplasma pneumoniae pneumonia. 61
33347836 2020
39
Early prediction of necrotizing pneumonia from mycoplasma pneumoniae pneumonia with large pulmonary lesions in children. 61
33149220 2020
40
Correlation Between the Clinical Severity, Bacterial Load, and Inflammatory Reaction in Children with Mycoplasma Pneumoniae Pneumonia. 61
33123897 2020
41
Acute Hypoxic Respiratory Failure and Septic Shock Secondary to Mycoplasma Pneumoniae Pneumonia Complicated by Heroin Overdose. 61
33240691 2020
42
Rational stepwise approach for Mycoplasma pneumoniae pneumonia in children. 61
33268306 2020
43
Interleukin-23 derived from CD16+ monocytes drives IL-17 secretion by TLR4 pathway in children with mycoplasma pneumoniae pneumonia. 61
32726660 2020
44
Zinc oxide nanoparticles from Corydalis yanhusuo attenuated the mycoplasmal pneumonia in mice through inhibiting the MAPKs signaling pathway. 61
32446872 2020
45
Macrolide-resistant Mycoplasma pneumoniae pneumonia in transplantation: Increasingly typical? 61
32386104 2020
46
Effects of different doses of methylprednisolone on TNF-α, IL-6, and IL-13 in serum and bronchoalveolar lavage fluid of children with severe mycoplasma pneumoniae pneumonia. 61
32996302 2020
47
Significance changes in the levels of myocardial enzyme in the child patients with Mycoplasma Pneumoniae Pneumonia. 61
33040783 2020
48
[Influencing factors for the clinical effect of bronchoalveolar lavage in children with Mycoplasma pneumoniae pneumonia and atelectasis]. 61
32933631 2020
49
Dynamic change of Mycoplasma pneumoniae pneumonia in hospitalized children in a general hospital: a 3-year retrospective analysis. 61
32953550 2020
50
Impact of viral coinfection and macrolide-resistant mycoplasma infection in children with refractory Mycoplasma pneumoniae pneumonia. 61
32847534 2020

Variations for Mycoplasma Pneumoniae Pneumonia

Expression for Mycoplasma Pneumoniae Pneumonia

Search GEO for disease gene expression data for Mycoplasma Pneumoniae Pneumonia.

Pathways for Mycoplasma Pneumoniae Pneumonia

Pathways related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.11 TNF TLR2 MUC1 IL6 IL4 IL23A
2
Show member pathways
13.88 TNF MUC1 IL6 IL4 IL23A IL18
3
Show member pathways
13.74 TNF IL6 IL4 IL23A IL18 IL17A
4
Show member pathways
13.6 TNF IL6 IL4 IL23A IL18 IL17A
5
Show member pathways
13.51 TNF TLR2 IL6 IL4 IL23A IL18
6
Show member pathways
13.45 TNF MUC1 IL6 IL4 IL23A IL18
7
Show member pathways
13.4 TNF IL6 IL4 IL23A IL18 IL17A
8
Show member pathways
13.3 TNF TLR2 SFTPD IL6 IL18 IL10
9
Show member pathways
12.98 TNF IL6 IL4 IL17A IL13 IL10
10 12.86 IL6 IL4 IL23A IL13 IFNG
11
Show member pathways
12.85 TNF TLR2 IL6 IL18 IFNG
12 12.83 TNF TLR2 IL6 IFNG C3
13
Show member pathways
12.72 TNF IL6 IL23A IL18 IL17A IL10
14 12.7 TNF TLR2 IL4 IL17A IL10 IFNG
15
Show member pathways
12.7 TNF TLR2 IL6 IL4 IL17A IL10
16
Show member pathways
12.69 TNF IL4 IL18 IL10 IFNG
17
Show member pathways
12.64 TNF TLR2 IL6 IL4 IL23A IL18
18
Show member pathways
12.55 IL6 IL4 IL23A IL13 IL10 IFNG
19
Show member pathways
12.45 TNF TLR2 IL6 IL18
20 12.43 TNF IL18 CSF2 C3
21
Show member pathways
12.43 TNF IL6 IL4 IFNG CRP
22
Show member pathways
12.43 TNF TLR2 IL6 IL4 IL17A IL13
23
Show member pathways
12.41 TNF TLR2 IL4 IL10 IFNG C3
24
Show member pathways
12.37 TNF IL6 IL18 IL10
25
Show member pathways
12.36 TNF IL6 IL4 IL18 IL17A IL13
26
Show member pathways
12.33 TNF TLR2 IL6 IL18 F3
27 12.31 TNF TLR2 IL6 IL23A IL18 IL10
28
Show member pathways
12.29 TNF TLR2 SFTPD MUC1 IL6 IL4
29
Show member pathways
12.27 TNF IL6 IL23A IL10
30 12.24 TNF TLR2 IL6 IFNG
31 12.23 TNF IL6 IL13 IL10
32 12.16 TNF IL6 IL18 IL10
33 12.13 TNF IL6 IL4 IL10 IFNG CSF2
34 12.09 TNF IL6 IL4 IFNG
35 12.07 TNF TLR2 IL6 IL10 IFNG CSF2
36 12 TNF IL6 IL4 CSF2
37
Show member pathways
11.97 IL6 IL23A IL17A CSF2
38
Show member pathways
11.97 TLR2 IL6 IL4 IL23A IL17A IFNG
39 11.96 IL6 IL4 IL13 IFNG CSF2
40 11.92 TNF IL6 IL23A IL10 C3
41 11.89 TNF TLR2 IL6 IL23A IL18 IL17A
42
Show member pathways
11.87 TNF IL4 IFNG CSF2
43 11.86 TNF IL6 IL23A IL10 IFNG CSF2
44
Show member pathways
11.86 TNF TLR2 IL6 IL18 IL17A IL10
45 11.85 TNF TLR2 IL6 IL4 IL10
46 11.82 TNF IL6 IL4 IL13 CSF2
47
Show member pathways
11.79 TNF IL6 IFNG CSF2
48 11.77 TNF TLR2 IL6 IL18 C3
49 11.76 TNF IL4 IL23A IL18 IL17A IL13
50 11.66 TNF TLR2 IL18 IFNG

GO Terms for Mycoplasma Pneumoniae Pneumonia

Cellular components related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 TNF SFTPD MUC1 IL6 IL4 IL23A
2 external side of plasma membrane GO:0009897 9.55 TNF IL17A IL13 CD276 ACE
3 extracellular space GO:0005615 9.53 TNF SFTPD MUC1 IL6 IL4 IL23A

Biological processes related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

(show top 50) (show all 63)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 10.25 TNF TLR2 IL6 IL4 IL23A IL18
2 innate immune response GO:0045087 10.16 TLR2 SFTPD IL23A IL17A CRP C3
3 regulation of immune response GO:0050776 10.02 SFTPD IL4 CD276 C3
4 response to lipopolysaccharide GO:0032496 10 TLR2 IL13 IL10 CYP1A1
5 cellular response to lipopolysaccharide GO:0071222 10 TNF IL6 IL10 CSF2
6 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.99 TNF TLR2 IL6 IL18
7 inflammatory response GO:0006954 9.97 TNF TLR2 IL6 IL23A IL18 IL17A
8 positive regulation of gene expression GO:0010628 9.96 TNF TLR2 IL6 IL4 IL18 IL13
9 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.93 TNF TLR2 IL23A IL18
10 positive regulation of interferon-gamma production GO:0032729 9.93 TNF IL23A IL18 CD276
11 defense response to Gram-positive bacterium GO:0050830 9.93 TNF TLR2 IL6 IL17A CRP
12 positive regulation of T cell proliferation GO:0042102 9.92 IL6 IL4 IL23A CD276
13 positive regulation of inflammatory response GO:0050729 9.92 TNF TLR2 IL23A IL18 IFNG
14 positive regulation of smooth muscle cell proliferation GO:0048661 9.91 TNF IL6 IL18 IL13
15 regulation of insulin secretion GO:0050796 9.9 TNF IL6 IFNG
16 cellular response to organic cyclic compound GO:0071407 9.9 TNF IL18 CYP1A1
17 positive regulation of interleukin-8 production GO:0032757 9.9 TNF TLR2 IL6 F3
18 response to glucocorticoid GO:0051384 9.89 TNF IL6 IL10
19 humoral immune response GO:0006959 9.89 TNF IL6 IFNG
20 positive regulation of interleukin-1 beta production GO:0032731 9.89 TNF IL6 IL17A IFNG
21 positive regulation of cytokine production GO:0001819 9.88 TNF IL10 IFNG
22 positive regulation of interleukin-6 production GO:0032755 9.88 TNF TLR2 IL6 IL17A IFNG
23 positive regulation of phagocytosis GO:0050766 9.87 TNF SFTPD IFNG C3
24 positive regulation of interleukin-12 production GO:0032735 9.86 TLR2 IL23A IL17A IFNG
25 negative regulation of endothelial cell apoptotic process GO:2000352 9.85 IL4 IL13 IL10
26 positive regulation of chemokine production GO:0032722 9.85 TNF TLR2 IL6 IFNG
27 positive regulation of tumor necrosis factor production GO:0032760 9.85 TLR2 IL6 IL23A IL17A IFNG
28 positive regulation of JAK-STAT cascade GO:0046427 9.84 TNF IL6 IL10
29 lipopolysaccharide-mediated signaling pathway GO:0031663 9.84 TNF TLR2 IL18
30 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.83 TNF IL6 IL17A
31 positive regulation of immunoglobulin production GO:0002639 9.82 IL6 IL13 IL10
32 positive regulation of interleukin-17 production GO:0032740 9.81 IL6 IL23A IL18
33 positive regulation of interleukin-10 production GO:0032733 9.8 TLR2 IL6 IL4 IL23A IL13
34 macrophage activation GO:0042116 9.79 IL4 IL13 CSF2
35 positive regulation of neuroinflammatory response GO:0150078 9.78 TNF IL6 IL18
36 microglial cell activation GO:0001774 9.77 TNF TLR2 IL4 IL13 IFNG
37 positive regulation of MHC class II biosynthetic process GO:0045348 9.76 IL4 IL10 IFNG
38 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.76 TNF IL6 IL4 IL23A IL18 IL13
39 negative regulation of lipid storage GO:0010888 9.75 TNF IL6 CRP
40 negative regulation of amyloid-beta clearance GO:1900222 9.73 TNF IFNG
41 positive regulation of podosome assembly GO:0071803 9.73 TNF CSF2
42 response to molecule of bacterial origin GO:0002237 9.73 TLR2 IL10
43 neutrophil mediated immunity GO:0002446 9.73 IL6 ACE
44 positive regulation of osteoclast differentiation GO:0045672 9.73 TNF IL23A IL17A IFNG
45 immune response GO:0006955 9.73 TNF TLR2 IL6 IL4 IL23A IL18
46 positive regulation of mast cell degranulation GO:0043306 9.72 IL4 IL13
47 endothelial cell apoptotic process GO:0072577 9.72 TNF IL10
48 positive regulation of natural killer cell proliferation GO:0032819 9.72 IL23A IL18
49 vascular endothelial growth factor production GO:0010573 9.71 TNF IL6
50 positive regulation of mononuclear cell migration GO:0071677 9.71 TNF IL4

Molecular functions related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.93 TNF TLR2 SFTPD MUC1 IL6 IL4
2 growth factor activity GO:0008083 9.46 IL6 IL4 IL10 CSF2
3 cytokine activity GO:0005125 9.32 TNF IL6 IL4 IL23A IL18 IL17A

Sources for Mycoplasma Pneumoniae Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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