MCID: MYC087
MIFTS: 55

Mycoplasma Pneumoniae Pneumonia

Categories: Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Mycoplasma Pneumoniae Pneumonia

MalaCards integrated aliases for Mycoplasma Pneumoniae Pneumonia:

Name: Mycoplasma Pneumoniae Pneumonia 12 15
Mycoplasmal Pneumonia 12 76 53
Pneumonia Due to Mycoplasma Pneumoniae 12
Cold Agglutinin Positive Pneumonia 12
Pneumonia Due to Eaton's Agent 12
Pneumonia, Mycoplasma 44
Mycoplasma Pneumonia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13276
ICD10 33 J15.7 B96.0
ICD9CM 35 483.0
MeSH 44 D011019

Summaries for Mycoplasma Pneumoniae Pneumonia

Disease Ontology : 12 A bacterial pneumonia that is caused by the bacterial species Mycoplasma pneumoniae. The symptoms include chest pain, chills, dry cough which is not bloody, excessive sweating, fever, headache and sore throat.

MalaCards based summary : Mycoplasma Pneumoniae Pneumonia, also known as mycoplasmal pneumonia, is related to pneumonia and myelitis. An important gene associated with Mycoplasma Pneumoniae Pneumonia is CRP (C-Reactive Protein), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Azithromycin and Levofloxacin have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and heart, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Wikipedia : 76 Atypical pneumonia, also known as walking pneumonia, is the type of pneumonia not caused by one of the... more...

Related Diseases for Mycoplasma Pneumoniae Pneumonia

Diseases related to Mycoplasma Pneumoniae Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 562)
# Related Disease Score Top Affiliating Genes
1 pneumonia 30.9 CRP IL10 IL13 IL6 TLR2 TNF
2 myelitis 30.6 IL17A IL6 TNF
3 transverse myelitis 30.3 IL10 IL17A IL6 TNF
4 purpura 30.3 CRP IL6 TNF
5 acute transverse myelitis 30.2 IL10 IL6
6 neuritis 30.2 IFNG IL4 TNF
7 exanthem 30.1 CRP IL6 TNF
8 pertussis 30.1 IL10 IL6 TNF
9 rheumatic fever 30.0 IL10 IL6 TNF
10 cold agglutinin disease 30.0 CRP IL6
11 adult respiratory distress syndrome 30.0 IL10 IL6 TNF
12 hemophagocytic lymphohistiocytosis 30.0 IFNG IL10 IL18 TNF
13 anterior uveitis 29.9 IL6 TLR2 TNF
14 viral pneumonia 29.9 CRP IL17A IL6
15 severe acute respiratory syndrome 29.9 CRP IFNG TNF
16 bacterial pneumonia 29.9 CRP IL17A IL6
17 heart disease 29.9 CRP IL10 IL6 TNF
18 rheumatic heart disease 29.8 IL10 IL4 IL6 TNF
19 adult-onset still's disease 29.8 CRP IL18 IL6 TNF
20 kawasaki disease 29.8 CRP IL10 IL6 TNF
21 central nervous system disease 29.8 IFNG IL17A IL6 TNF
22 nervous system disease 29.8 CRP IFNG IL10 IL6 TNF
23 arteries, anomalies of 29.7 CRP IL6 TNF
24 hyperlucent lung 29.7 IFNG IL10 IL4
25 cerebrovascular disease 29.7 CRP IL6 TNF
26 pericarditis 29.7 CRP IFNG IL6 TNF
27 aseptic meningitis 29.7 IFNG IL10 TNF
28 acute pancreatitis 29.7 CRP IL10 IL18 IL6
29 pleurisy 29.7 CRP IFNG TNF
30 spondylitis 29.6 CRP IL17A IL6 TNF
31 haemophilus influenzae 29.6 TLR2 TNF
32 lichen planus 29.6 IFNG IL4 TNF
33 synovitis 29.6 CRP IL18 IL6 TNF
34 polyradiculoneuropathy 29.6 IFNG IL10 IL17A
35 uveitis 29.6 IFNG IL10 IL17A IL4 TNF
36 bronchiolitis obliterans 29.5 IFNG IL10 IL17A IL6 TNF
37 intermediate uveitis 29.5 IFNG IL10 IL6 TNF
38 hemorrhagic fever 29.5 IFNG IL10 IL6 TNF
39 dengue hemorrhagic fever 29.5 IFNG IL10 IL6 TNF
40 osteomyelitis 29.5 IFNG IL10 IL6 TNF
41 temporal arteritis 29.5 CRP IFNG IL6 TNF
42 myocardial infarction 29.5 CRP IL10 IL6 TNF
43 myasthenia gravis 29.5 IFNG IL10 IL4 TNF
44 respiratory allergy 29.4 IL10 IL13 IL17A IL4
45 measles 29.2 IFNG IL4 IL6 TLR2
46 meningitis 29.2 CRP IFNG IL10 IL6 TLR2 TNF
47 q fever 29.2 IFNG IL10 IL4 IL6 TLR2 TNF
48 otitis media 29.1 IL10 IL4 IL6 TLR2 TNF
49 bronchiolitis 29.1 CRP IFNG IL10 IL13 IL17A IL4
50 chlamydia 29.1 CRP IFNG IL10 IL4 IL6 TLR2

Graphical network of the top 20 diseases related to Mycoplasma Pneumoniae Pneumonia:



Diseases related to Mycoplasma Pneumoniae Pneumonia

Symptoms & Phenotypes for Mycoplasma Pneumoniae Pneumonia

MGI Mouse Phenotypes related to Mycoplasma Pneumoniae Pneumonia:

46 (show all 20)
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 10.22 IFNG IL10 IL13 IL17A IL18 IL4
2 homeostasis/metabolism MP:0005376 10.22 CRP IFNG IL10 IL13 IL17A IL18
3 immune system MP:0005387 10.21 CRP IFNG IL10 IL13 IL17A IL18
4 growth/size/body region MP:0005378 10.2 IFNG IL10 IL13 IL17A IL18 IL4
5 cellular MP:0005384 10.19 IFNG IL10 IL13 IL18 IL4 IL6
6 hematopoietic system MP:0005397 10.19 IFNG IL10 IL13 IL17A IL18 IL4
7 endocrine/exocrine gland MP:0005379 10.16 IFNG IL10 IL13 IL17A IL4 IL6
8 cardiovascular system MP:0005385 10.14 CRP IFNG IL10 IL18 IL6 TLR2
9 mortality/aging MP:0010768 10.11 IFNG IL10 IL13 IL17A IL18 IL4
10 integument MP:0010771 10.1 IFNG IL10 IL13 IL18 IL4 IL6
11 muscle MP:0005369 9.98 IFNG IL10 IL13 IL18 IL6 TLR2
12 craniofacial MP:0005382 9.97 IFNG IL10 IL17A IL4 TNF
13 nervous system MP:0003631 9.97 IFNG IL10 IL13 IL18 IL4 IL6
14 liver/biliary system MP:0005370 9.95 IFNG IL10 IL4 IL6 TLR2 TNF
15 neoplasm MP:0002006 9.8 IFNG IL10 IL6 TLR2 TNF
16 no phenotypic analysis MP:0003012 9.8 IFNG IL10 IL13 IL17A IL4 TNF
17 respiratory system MP:0005388 9.76 IFNG IL10 IL13 IL17A IL4 IL6
18 reproductive system MP:0005389 9.73 IFNG IL10 IL13 IL4 IL6 TNF
19 skeleton MP:0005390 9.56 IFNG IL10 IL13 IL17A IL4 IL6
20 vision/eye MP:0005391 9.1 IFNG IL10 IL18 IL4 IL6 TNF

Drugs & Therapeutics for Mycoplasma Pneumoniae Pneumonia

Drugs for Mycoplasma Pneumoniae Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 65)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 2,Not Applicable 83905-01-5 55185 447043
2
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
3
Methylprednisolone Approved, Vet_approved Phase 4,Not Applicable 83-43-2 6741
4
Prednisolone phosphate Approved, Vet_approved Phase 4,Not Applicable 302-25-0
5
Methylprednisolone hemisuccinate Approved Phase 4,Not Applicable 2921-57-5
6
Ofloxacin Approved Phase 4 82419-36-1 4583
7
Prednisolone Approved, Vet_approved Phase 4,Not Applicable 50-24-8 5755
8
Prednisolone hemisuccinate Experimental Phase 4,Not Applicable 2920-86-7
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
10 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
11 Gastrointestinal Agents Phase 4,Not Applicable
12 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
13 Topoisomerase Inhibitors Phase 4,Not Applicable
14 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
15 Methylprednisolone acetate Phase 4,Not Applicable
16 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
17 Anti-Infective Agents, Urinary Phase 4
18 Hormone Antagonists Phase 4,Not Applicable
19 Antineoplastic Agents, Hormonal Phase 4,Not Applicable
20 Peripheral Nervous System Agents Phase 4,Not Applicable
21 Protective Agents Phase 4,Not Applicable
22 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
23 Prednisolone acetate Phase 4,Not Applicable
24 Neuroprotective Agents Phase 4,Not Applicable
25 Hormones Phase 4,Not Applicable
26 Anti-Inflammatory Agents Phase 4,Not Applicable
27 Renal Agents Phase 4
28 glucocorticoids Phase 4,Not Applicable
29 Autonomic Agents Phase 4,Not Applicable
30 Antiemetics Phase 4,Not Applicable
31
Ceftriaxone Approved Phase 3 73384-59-5 5479530 5361919
32
Clarithromycin Approved Phase 3 81103-11-9 84029
33 Cephalosporins Phase 3,Not Applicable
34 beta-Lactams Phase 3
35 Lactams Phase 3
36 Cytochrome P-450 CYP3A Inhibitors Phase 3
37 Antitubercular Agents Phase 2,Not Applicable
38
Erythromycin Approved, Investigational, Vet_approved Not Applicable 114-07-8 12560
39
Doxycycline Approved, Investigational, Vet_approved Not Applicable 564-25-0 54671203
40
Norgestimate Approved, Investigational Not Applicable 35189-28-7 6540478
41
Polyestradiol phosphate Approved Not Applicable 28014-46-2
42
Ethinyl Estradiol Approved Not Applicable 57-63-6 5991
43
Moxifloxacin Approved, Investigational Not Applicable 354812-41-2, 151096-09-2 152946
44
Cefuroxime Approved Not Applicable 55268-75-2 5361202 5479529
45
Estradiol Approved, Investigational, Vet_approved Not Applicable 50-28-2 5757
46 Estradiol valerate Approved, Investigational, Vet_approved Not Applicable 979-32-8
47 Erythromycin stearate Not Applicable
48 Erythromycin Estolate Not Applicable
49 Erythromycin Ethylsuccinate Not Applicable
50 Antimalarials Not Applicable

Interventional clinical trials:

(show all 23)
# Name Status NCT ID Phase Drugs
1 AZithromycin Against pLacebo in Exacerbations of Asthma Completed NCT01444469 Phase 4 Zithromax;Placebo
2 Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia Recruiting NCT02618057 Phase 4 Prednisolone;Levofloxacin
3 Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Completed NCT00509106 Phase 3 Ceftaroline fosamil for Injection;Ceftriaxone;Placebo
4 Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Completed NCT00621504 Phase 3 Ceftaroline fosamil for Injection;IV Ceftriaxone;Placebo;Clarithromycin
5 Antibiotic Treatment Trial for the PANDAS/PANS Phenotype Completed NCT01617083 Phase 2 Azithromycin;Placebo
6 Prevalence and Clinical Significance of Co-infection of Mycoplasma Pneumoniae in Patients With Pulmonary Tuberculosis Unknown status NCT00926601
7 Etiology Study of Kawasaki Disease Unknown status NCT00154596
8 Effectiveness Study of Integrative Treatment for Pediatric Community Acquired Pneumonia Unknown status NCT02362906 Not Applicable Xiyanping injection;wind-heat formula granules;phlegm-heat formula granules;Fu-xiong San;second generation cephalosporin;Erythromycin;Azithromycin
9 Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting Completed NCT00207584 Not Applicable Doxycycline treatment
10 Detection of Mycoplasma Pneumoniae Completed NCT02511262
11 Evaluation of Pathogenesis and Diagnosis of Mycoplasma Pneumoniae Community-acquired Pneumonia (CAP) Completed NCT03613636
12 The Optimization of Mycoplasm Pneumonia Antibiotic Therapy Completed NCT01259141 Not Applicable Moxifloxacin;Cephalosporins and azithromycin
13 Chlamydia and Mycoplasma in Coronary Artery Disease Completed NCT00561028
14 Etiology of Community Acquired Pneumonia Completed NCT00471757
15 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
16 Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP) Recruiting NCT02303587 Not Applicable methylprednisolone
17 Treatment of Macrolide-resistant Mycoplasma Pneumoniae Recruiting NCT03530319 Not Applicable Doxycycline;Azithromycin
18 Assessment of Pharyngeal Carriage of Microorganisms Responsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims. Recruiting NCT02868541
19 A Molecular Toolkit for the Microbial Investigation of Severe Community Acquired Pneumonia Recruiting NCT02963142
20 DiagNostic Study of Low-dose CT and multipleX PCR on Antibiotic Treatment and Outcome of Community-Acquired Pneumonia Recruiting NCT03360851 Not Applicable
21 Comparative Autoantibody and Immunologic Cell Marker Study Enrolling by invitation NCT02422875
22 Methylprednisolone Pulse Macrolide Therapy for Refractory Mycoplasma Pneumoniae Pneumonia in Children Terminated NCT01217099 Not Applicable methylprednisolone;azithromycin
23 Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For CAP Withdrawn NCT01662258 Not Applicable

Search NIH Clinical Center for Mycoplasma Pneumoniae Pneumonia

Cochrane evidence based reviews: pneumonia, mycoplasma

Genetic Tests for Mycoplasma Pneumoniae Pneumonia

Anatomical Context for Mycoplasma Pneumoniae Pneumonia

MalaCards organs/tissues related to Mycoplasma Pneumoniae Pneumonia:

41
Lung, T Cells, Heart, Brain, Bone, Lymph Node, Eye

Publications for Mycoplasma Pneumoniae Pneumonia

Articles related to Mycoplasma Pneumoniae Pneumonia:

(show top 50) (show all 314)
# Title Authors Year
1
Viral and bacterial co-infection in hospitalised children with refractory Mycoplasma pneumoniae pneumonia. ( 29970200 )
2018
2
Reply to 'Influenza follicles and their buds as early diagnostic markers of influenza: typical images' and demonstration of lymphoid follicles in the posterior pharyngeal walls of patients with mycoplasmal pneumonia. ( 29440479 )
2018
3
Contribution of Co-detected Respiratory Viruses and Patient Age to the Clinical Manifestations of Mycoplasma Pneumoniae Pneumonia in Children. ( 29095244 )
2018
4
Leukoagglutination, Mycoplasma pneumoniae Pneumonia, and EDTA Acid Blood. ( 29192604 )
2018
5
Antimicrobial therapy of macrolide-resistant Mycoplasma pneumoniae pneumonia in children. ( 29212389 )
2018
6
Serum lactate dehydrogenase isoenzymes 4 plus 5 is a better biomarker than total lactate dehydrogenase for refractory Mycoplasma pneumoniae pneumonia in children. ( 29337082 )
2018
7
The timing of azithromycin treatment is not associated with the clinical prognosis of childhood Mycoplasma pneumoniae pneumonia in high macrolide-resistant prevalence settings. ( 29377957 )
2018
8
Refractory Mycoplasma pneumoniae pneumonia with concomitant acute cerebral infarction in a child: A case report and literature review. ( 29595632 )
2018
9
Clinical features of Mycoplasma pneumoniae pneumonia in older adults. ( 29722163 )
2018
10
The concordance between upper and lower respiratory microbiota in children with Mycoplasma pneumoniae pneumonia. ( 29789582 )
2018
11
Transcriptome Analysis of Bronchoalveolar Lavage Fluid From Children With Mycoplasma pneumoniae Pneumonia Reveals Natural Killer and T Cell-Proliferation Responses. ( 29967623 )
2018
12
The role of granulocyte macrophage colony stimulating factor in hospitalized children with Mycoplasma pneumoniae pneumonia. ( 30007865 )
2018
13
A 6-year-old girl with severe, focal Mycoplasma pneumoniae pneumonia. ( 30066973 )
2018
14
High expression of HMGB1 in children with refractory Mycoplasma pneumoniae pneumonia. ( 30157804 )
2018
15
Clinical effect of sequential therapy with azithromycin in children mycoplasma pneumoniae pneumonia. ( 30203754 )
2018
16
Mycoplasma pneumoniae Pneumonia with Worsening Pleural Effusion Despite Treatment with Appropriate Antimicrobials: Case report. ( 30210860 )
2018
17
Serum Tumor Necrosis Factor-α and Interferon-γ Levels in Pediatric Mycoplasma pneumoniae Pneumonia: A Systematic Review and Meta-Analysis. ( 30275916 )
2018
18
Ameliorative Effects of Infantile Feire Kechuan Oral Solution on Mycoplasma Pneumoniae Pneumonia in Infant Mouse and Rat Models. ( 30305831 )
2018
19
Therapeutic Efficacy and Safety of Prolonged Macrolide, Corticosteroid, Doxycycline, and Levofloxacin against Macrolide-Unresponsive Mycoplasma pneumoniae Pneumonia in Children. ( 30344461 )
2018
20
Low Bacterial Co-infection Invalidates the Early Use of Non-anti-Mycoplasma pneumoniae Antibiotics in Pediatric Refractory Mycoplasma pneumoniae Pneumonia Patients. ( 30416990 )
2018
21
Mycoplasma Pneumoniae Pneumonia: Walking Pneumonia Can Cripple the Susceptible. ( 30425761 )
2018
22
Assessment of levels of D-dimer and interferon-γ in pediatric patients with Mycoplasma pneumoniae pneumonia and its clinical implication. ( 30546408 )
2018
23
Wanted: The Best Second Option to Treat Macrolide-Unresponsive Mycoplasmal Pneumonia in Children. ( 30344464 )
2018
24
Role of E-selectin for diagnosing myocardial injury in paediatric patients with mycoplasma pneumoniae pneumonia. ( 26843511 )
2017
25
Association of the ACE, GSTM1, IL-6, NOS3, and CYP1A1 polymorphisms with susceptibility of mycoplasma pneumoniae pneumonia in Chinese children. ( 28403117 )
2017
26
Determinants for swine mycoplasmal pneumonia reproduction under experimental conditions: A systematic review and recursive partitioning analysis. ( 28742802 )
2017
27
The Correlation between Chest X-ray Scores and the Clinical Findings in Children and Adults with Mycoplasma pneumoniae Pneumonia. ( 28943541 )
2017
28
Increased Serum Interleukin-10 but not Interleukin-4 Level in Children with Mycoplasma pneumoniae Pneumonia. ( 28057814 )
2017
29
Prediction of Bronchial Mucus Plugs Formation in Patients with Refractory Mycoplasma Pneumoniae Pneumonia. ( 27686558 )
2017
30
iTRAQ-based Quantitative Proteomics Study in Patients with Refractory Mycoplasma pneumoniae Pneumonia. ( 28003598 )
2017
31
Corrigendum to "Imbalance of peripheral blood Th17 and Treg responses in children with refractory Mycoplasma pneumoniae pneumonia" [J Infect Chemother 22 (2016) 162-166]. ( 28117170 )
2017
32
Effects of methylprednisolone or immunoglobulin when added to standard treatment with intravenous azithromycin for refractory Mycoplasma pneumoniae pneumonia in children. ( 28130749 )
2017
33
A severe Mycoplasma pneumoniae pneumonia inducing an acute antibody-mediated pulmonary graft rejection. ( 28144069 )
2017
34
Therapeutic efficacy of azithromycin, clarithromycin, minocycline and tosufloxacin against macrolide-resistant and macrolide-sensitive Mycoplasma pneumoniae pneumonia in pediatric patients. ( 28288170 )
2017
35
Transcriptome analysis of bronchoalveolar lavage fluid from children with severe Mycoplasma pneumoniae pneumonia reveals novel gene expression and immunodeficiency. ( 28302172 )
2017
36
Histological findings in severe Mycoplasma pneumoniae pneumonia. ( 28513419 )
2017
37
Radiologic findings as a determinant and no effect of macrolide resistance on clinical course of Mycoplasma pneumoniae pneumonia. ( 28592263 )
2017
38
Prevalence and clinical manifestations of macrolide resistant Mycoplasma pneumoniae pneumonia in Korean children. ( 28592978 )
2017
39
Peculiar Cold-Induced Leukoagglutination in Mycoplasma pneumoniae Pneumonia. ( 28611012 )
2017
40
Evaluation of variation in coagulation among children with Mycoplasma pneumoniae pneumonia: a case-control study. ( 28643533 )
2017
41
Comparison of the ameliorative effects of Qingfei Tongluo formula and azithromycin on Mycoplasma pneumoniae pneumonia. ( 28664473 )
2017
42
Mechanism of resistance acquisition and treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children. ( 28690643 )
2017
43
CYTOKINES AS THE PREDICTORS OF SEVERE MYCOPLASMA PNEUMONIAE PNEUMONIA IN CHILDREN (REVIEW). ( 28726662 )
2017
44
Spontaneous pneumomediastinum, emphysema, and pulmonary bullae associated with refractory Mycoplasma pneumoniae pneumonia in a child. ( 28752681 )
2017
45
Effect of Qingfei Mixture () on pediatric mycoplasma pneumoniae pneumonia with phlegm heat obstructing Fei (Lung) syndrome. ( 28861888 )
2017
46
Unexplained Dyspnea in a Young Adult with Epstein-Barr Virus Infectious Mononucleosis: Pulmonary Involvement or Co-Infection with Mycoplasma pneumoniae Pneumonia? ( 28869530 )
2017
47
Comparison of Efficacy of Antimicrobial Agents Among Hospitalized Patients With Mycoplasma pneumoniae Pneumonia in Japan During Large Epidemics of Macrolide-Resistant M. pneumoniae Infections: A Nationwide Observational Study. ( 29020161 )
2017
48
Interleukin 17A as a good predictor of the severity of Mycoplasma pneumoniae pneumonia in children. ( 29021577 )
2017
49
Additional corticosteroids or alternative antibiotics for the treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia. ( 29042865 )
2017
50
Adjunctive corticosteroid therapy for inpatients with Mycoplasma pneumoniae pneumonia. ( 29284447 )
2017

Variations for Mycoplasma Pneumoniae Pneumonia

Expression for Mycoplasma Pneumoniae Pneumonia

Search GEO for disease gene expression data for Mycoplasma Pneumoniae Pneumonia.

Pathways for Mycoplasma Pneumoniae Pneumonia

Pathways related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

(show top 50) (show all 70)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.96 CRP IFNG IL10 IL13 IL17A IL18
2
Show member pathways
13.75 IL10 IL13 IL17A IL18 IL4 IL6
3
Show member pathways
13.64 IFNG IL10 IL13 IL17A IL18 IL4
4
Show member pathways
13.52 IFNG IL10 IL13 IL17A IL18 IL4
5
Show member pathways
13.4 IL10 IL13 IL17A IL18 IL4 IL6
6
Show member pathways
13.34 IFNG IL10 IL13 IL17A IL18 IL4
7
Show member pathways
13.29 IL10 IL13 IL17A IL18 IL4 IL6
8
Show member pathways
13.02 IFNG IL10 IL18 IL6 TLR2 TNF
9
Show member pathways
12.9 IFNG IL10 IL13 IL17A IL18 IL4
10
Show member pathways
12.82 IFNG IL13 IL18 IL4 IL6 TLR2
11 12.76 IFNG IL13 IL4 IL6
12
Show member pathways
12.7 IFNG IL18 IL6 TNF
13
Show member pathways
12.66 IFNG IL10 IL18 IL4 TNF
14
Show member pathways
12.64 IFNG IL10 IL17A IL18 IL6 TNF
15 12.61 IFNG IL10 IL17A IL4 TLR2 TNF
16
Show member pathways
12.48 IFNG IL10 IL17A IL4 IL6 TNF
17
Show member pathways
12.45 IFNG IL10 IL13 IL4 IL6
18
Show member pathways
12.4 CRP IFNG IL4 IL6 TNF
19
Show member pathways
12.39 IFNG IL13 IL17A IL4 IL6 TLR2
20
Show member pathways
12.35 IFNG IL10 IL13 IL17A IL18 IL4
21
Show member pathways
12.33 IFNG IL10 IL4 TLR2 TNF
22 12.31 IFNG IL10 IL18 IL6 TLR2 TNF
23
Show member pathways
12.29 IFNG IL10 IL13 IL17A IL18 IL4
24
Show member pathways
12.26 IL18 IL6 TLR2 TNF
25
Show member pathways
12.26 IFNG IL4 IL6 TLR2 TNF
26 12.23 IFNG IL6 TLR2 TNF
27 12.22 IL6 TLR2 TNF
28 12.22 IL10 IL13 IL6 TNF
29
Show member pathways
12.2 IL6 TLR2 TNF
30
Show member pathways
12.15 IL10 IL6 TNF
31
Show member pathways
12.13 IFNG IL13 IL4 IL6 TLR2 TNF
32
Show member pathways
12.12 IFNG IL10 IL13 IL17A IL18 IL4
33
Show member pathways
12.11 IFNG IL10 IL17A IL18 IL6 TLR2
34 12.08 IFNG IL10 IL4 IL6 TNF
35 12.07 IFNG IL4 IL6 TNF
36 11.97 IFNG IL10 IL6 TLR2 TNF
37 11.97 IL10 IL13 IL17A IL18 IL4 IL6
38
Show member pathways
11.96 IFNG IL18 IL4
39 11.96 IFNG IL17A IL18 IL6 TLR2 TNF
40 11.89 IL4 IL6 TNF
41 11.89 IFNG IL13 IL4 IL6
42 11.85 IFNG IL10 IL6
43 11.84 IFNG IL10 IL6 TNF
44 11.83 IFNG IL18 IL6
45
Show member pathways
11.78 IFNG IL4 TNF
46 11.78 IL10 IL6 TNF
47 11.77 IL13 IL4 IL6 TNF
48 11.7 IL18 IL6 TLR2 TNF
49 11.7 IFNG IL10 IL13 IL17A IL18 IL4
50
Show member pathways
11.69 IFNG IL6 TNF

GO Terms for Mycoplasma Pneumoniae Pneumonia

Cellular components related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CRP IFNG IL10 IL13 IL17A IL18
2 extracellular space GO:0005615 9.28 CRP IFNG IL10 IL13 IL17A IL18

Biological processes related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.87 IL10 IL13 IL17A IL18 IL4 IL6
2 response to lipopolysaccharide GO:0032496 9.86 IL10 IL13 TLR2
3 cellular response to lipopolysaccharide GO:0071222 9.86 IL10 IL6 TNF
4 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.86 IL18 IL6 TLR2 TNF
5 regulation of signaling receptor activity GO:0010469 9.86 IFNG IL10 IL13 IL17A IL18 IL4
6 positive regulation of DNA-binding transcription factor activity GO:0051091 9.84 IL10 IL6 TNF
7 positive regulation of cold-induced thermogenesis GO:0120162 9.83 IL13 IL18 IL4
8 positive regulation of inflammatory response GO:0050729 9.83 IL18 TLR2 TNF
9 response to glucocorticoid GO:0051384 9.81 IL10 IL6 TNF
10 defense response to Gram-positive bacterium GO:0050830 9.81 CRP IL6 TLR2 TNF
11 positive regulation of interleukin-6 production GO:0032755 9.8 IL6 TLR2 TNF
12 humoral immune response GO:0006959 9.8 IFNG IL6 TNF
13 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.79 IL18 TLR2 TNF
14 positive regulation of smooth muscle cell proliferation GO:0048661 9.78 IL13 IL18 IL6 TNF
15 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.77 IFNG IL13 IL18 IL4 IL6
16 negative regulation of endothelial cell apoptotic process GO:2000352 9.76 IL10 IL13 IL4
17 positive regulation of gene expression GO:0010628 9.76 CRP IFNG IL13 IL18 IL4 IL6
18 lipopolysaccharide-mediated signaling pathway GO:0031663 9.75 IL18 TLR2 TNF
19 positive regulation of osteoclast differentiation GO:0045672 9.72 IFNG IL17A TNF
20 negative regulation of interleukin-6 production GO:0032715 9.71 IL10 TNF
21 positive regulation of cytokine secretion GO:0050715 9.71 IL10 TNF
22 positive regulation of interleukin-8 production GO:0032757 9.71 TLR2 TNF
23 positive regulation of chemokine production GO:0032722 9.71 IL6 TLR2 TNF
24 regulation of synapse organization GO:0050807 9.7 IL10 TNF
25 negative regulation of myoblast differentiation GO:0045662 9.7 IL18 TNF
26 negative regulation of neurogenesis GO:0050768 9.7 IL6 TNF
27 positive regulation of interleukin-12 production GO:0032735 9.7 IFNG TLR2
28 microglial cell activation GO:0001774 9.7 IL13 TLR2 TNF
29 positive regulation of protein complex assembly GO:0031334 9.69 IFNG TNF
30 protein import into nucleus, translocation GO:0000060 9.69 IFNG TNF
31 positive regulation of glial cell proliferation GO:0060252 9.68 IL6 TNF
32 positive regulation of macrophage activation GO:0043032 9.68 IL10 IL13
33 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.68 IFNG TNF
34 negative regulation of growth of symbiont in host GO:0044130 9.67 IL10 TNF
35 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.67 IL10 TNF
36 response to molecule of bacterial origin GO:0002237 9.67 IL10 TLR2
37 endothelial cell apoptotic process GO:0072577 9.65 IL10 TNF
38 positive regulation of MHC class II biosynthetic process GO:0045348 9.65 IL10 IL4
39 negative regulation of cytokine secretion involved in immune response GO:0002740 9.64 IL10 TNF
40 positive regulation of interleukin-23 production GO:0032747 9.63 IFNG IL17A
41 negative regulation of lipid storage GO:0010888 9.63 CRP IL6 TNF
42 regulation of isotype switching GO:0045191 9.62 IL10 IL4
43 negative regulation of complement-dependent cytotoxicity GO:1903660 9.61 IL13 IL4
44 positive regulation of neuroinflammatory response GO:0150078 9.61 IL18 IL6 TNF
45 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.6 IFNG TNF
46 receptor biosynthetic process GO:0032800 9.59 IL10 TNF
47 type 2 immune response GO:0042092 9.58 IL10 IL18 IL4
48 positive regulation of vitamin D biosynthetic process GO:0060557 9.57 IFNG TNF
49 inflammatory response GO:0006954 9.56 CRP IL10 IL13 IL17A IL18 IL6
50 immune response GO:0006955 9.28 IFNG IL10 IL13 IL17A IL18 IL4

Molecular functions related to Mycoplasma Pneumoniae Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.85 CRP IFNG IL10 IL13 IL17A IL18
2 cytokine receptor binding GO:0005126 9.26 IL13 IL4
3 cytokine activity GO:0005125 9.23 IFNG IL10 IL13 IL17A IL18 IL4
4 growth factor activity GO:0008083 9.13 IL10 IL4 IL6

Sources for Mycoplasma Pneumoniae Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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