MCID: MYC022
MIFTS: 32

Mycoplasmal Pneumonia

Categories: Rare diseases

Aliases & Classifications for Mycoplasmal Pneumonia

MalaCards integrated aliases for Mycoplasmal Pneumonia:

Name: Mycoplasmal Pneumonia 53
Mycoplasma Pneumonia 73

Classifications:



External Ids:

UMLS 73 C0032302

Summaries for Mycoplasmal Pneumonia

MalaCards based summary : Mycoplasmal Pneumonia, also known as mycoplasma pneumonia, is related to measles and bronchiolitis. An important gene associated with Mycoplasmal Pneumonia is IFNG (Interferon Gamma), and among its related pathways/superpathways are Regulation of IFNA signaling and NF-kappaB Signaling. The drugs Azithromycin and Ofloxacin have been mentioned in the context of this disorder. Affiliated tissues include testes, lung and heart.

Related Diseases for Mycoplasmal Pneumonia

Diseases related to Mycoplasmal Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 measles 29.5 IFNG IL4
2 bronchiolitis 29.5 IFNG IL4
3 pneumonia 10.8
4 hyperlucent lung 9.9 IFNG IL4
5 b-cell growth factor 9.9 IFNG IL4
6 baylisascariasis 9.9 IFNG IL4
7 penicillin allergy 9.9 IFNG IL4
8 atopic keratoconjunctivitis 9.9 IFNG IL4
9 microscopic colitis 9.9 IFNG IL4
10 urinary schistosomiasis 9.9 IFNG IL4
11 buruli ulcer 9.9 IFNG IL4
12 folliculitis 9.9 IFNG IL4
13 toxic oil syndrome 9.9 IFNG IL4
14 primary systemic mycosis 9.9 IFNG IL4
15 poliomyelitis 9.9 IFNG IL4
16 vulvovaginal candidiasis 9.9 IFNG IL4
17 hyper ige syndrome 9.9 IFNG IL4
18 orofacial granulomatosis 9.9 IFNG IL4
19 coccidiosis 9.9 IFNG IL4
20 eales disease 9.9 IFNG IL4
21 lichen disease 9.9 IFNG IL4
22 proliferative glomerulonephritis 9.9 IFNG IL4
23 cryptococcosis 9.9 IFNG IL4
24 paranasal sinus disease 9.9 IFNG IL4
25 rasmussen encephalitis 9.9 IFNG IL4
26 acute graft versus host disease 9.9 IFNG IL4
27 allergic conjunctivitis 9.9 IFNG IL4
28 opportunistic mycosis 9.9 IFNG IL4
29 vernal conjunctivitis 9.9 IFNG IL4
30 paracoccidioidomycosis 9.9 IFNG IL4
31 brucellosis 9.9 IFNG IL4
32 tonsillitis 9.9 IFNG IL4
33 leprosy 3 9.9 IFNG IL4
34 neuritis 9.9 IFNG IL4
35 spondyloarthropathy 9.9 IFNG IL4
36 conjunctivitis 9.9 IFNG IL4
37 parasitic protozoa infectious disease 9.9 IFNG IL4
38 keratoconjunctivitis 9.9 IFNG IL4
39 food allergy 9.9 IFNG IL4
40 allergic contact dermatitis 9.9 IFNG IL4
41 gastroenteritis 9.9 IFNG IL4
42 cutaneous leishmaniasis 9.9 IFNG IL4
43 primary bacterial infectious disease 9.9 IFNG IL4
44 aspergillosis 9.9 IFNG IL4
45 autoinflammation, lipodystrophy, and dermatosis syndrome 9.9 IFNG IL4
46 contact dermatitis 9.9 IFNG IL4
47 toxoplasmosis 9.9 IFNG IL4
48 bone inflammation disease 9.9 IFNG IL4
49 ige responsiveness, atopic 9.9 IFNG IL4
50 idiopathic interstitial pneumonia 9.9 IFNG IL4

Comorbidity relations with Mycoplasmal Pneumonia via Phenotypic Disease Network (PDN):


Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Ischemic Heart Disease
Respiratory Failure

Graphical network of the top 20 diseases related to Mycoplasmal Pneumonia:



Diseases related to Mycoplasmal Pneumonia

Symptoms & Phenotypes for Mycoplasmal Pneumonia

Drugs & Therapeutics for Mycoplasmal Pneumonia

Drugs for Mycoplasmal Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 63)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Azithromycin Approved Phase 4,Phase 2,Not Applicable 83905-01-5 55185 447043
2
Ofloxacin Approved Phase 4 82419-36-1 4583
3
Prednisolone Approved, Vet_approved Phase 4,Not Applicable 50-24-8 5755
4
Methylprednisolone Approved, Vet_approved Phase 4,Not Applicable 83-43-2 6741
5
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
6 Gastrointestinal Agents Phase 4,Not Applicable
7 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
8 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
9 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3
10 Topoisomerase Inhibitors Phase 4,Not Applicable
11 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2,Not Applicable
12 Prednisolone acetate Phase 4,Not Applicable
13 glucocorticoids Phase 4,Not Applicable
14 Renal Agents Phase 4
15 Methylprednisolone acetate Phase 4,Not Applicable
16 Methylprednisolone Hemisuccinate Phase 4,Not Applicable
17 Neuroprotective Agents Phase 4,Not Applicable
18 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
19 Hormone Antagonists Phase 4,Not Applicable
20 Hormones Phase 4,Not Applicable
21 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Not Applicable
22 Peripheral Nervous System Agents Phase 4,Not Applicable
23 Prednisolone hemisuccinate Phase 4,Not Applicable
24 Prednisolone phosphate Phase 4,Not Applicable
25 Antiemetics Phase 4,Not Applicable
26 Protective Agents Phase 4,Not Applicable
27 Anti-Inflammatory Agents Phase 4,Not Applicable
28 Autonomic Agents Phase 4,Not Applicable
29 Antineoplastic Agents, Hormonal Phase 4,Not Applicable
30
Ceftriaxone Approved Phase 3 73384-59-5 5479530 5361919
31
Clarithromycin Approved Phase 3 81103-11-9 84029
32 Cephalosporins Phase 3,Not Applicable
33 Cytochrome P-450 CYP3A Inhibitors Phase 3
34 Lactams Phase 3
35 beta-Lactams Phase 3
36 Antitubercular Agents Phase 2,Not Applicable
37
Erythromycin Approved, Investigational, Vet_approved Not Applicable 114-07-8 12560
38
Doxycycline Approved, Investigational, Vet_approved Not Applicable 564-25-0 54671203
39
Moxifloxacin Approved, Investigational Not Applicable 354812-41-2, 151096-09-2 152946
40 Estradiol valerate Approved, Investigational, Vet_approved Not Applicable 979-32-8
41
Cefuroxime Approved Not Applicable 55268-75-2 5361202 5479529
42
Norgestimate Approved, Investigational Not Applicable 35189-28-7 6540478
43
Estradiol Approved, Investigational, Vet_approved Not Applicable 50-28-2 5757
44
Ethinyl Estradiol Approved Not Applicable 57-63-6 5991
45
Polyestradiol phosphate Approved Not Applicable 28014-46-2
46 Erythromycin Estolate Not Applicable
47 Erythromycin Ethylsuccinate Not Applicable
48 Erythromycin stearate Not Applicable
49 cefuroxime axetil Not Applicable
50 Contraceptive Agents Not Applicable

Interventional clinical trials:

(show all 22)
# Name Status NCT ID Phase Drugs
1 AZithromycin Against pLacebo in Exacerbations of Asthma Completed NCT01444469 Phase 4 Zithromax;Placebo
2 Effects of Oral Steroid in Mycoplasma Pneumoniae Pneumonia Recruiting NCT02618057 Phase 4 Prednisolone;Levofloxacin
3 Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia Completed NCT00509106 Phase 3 Ceftaroline fosamil for Injection;Ceftriaxone;Placebo
4 Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia Completed NCT00621504 Phase 3 Ceftaroline fosamil for Injection;IV Ceftriaxone;Placebo;Clarithromycin
5 Antibiotic Treatment Trial for the PANDAS/PANS Phenotype Completed NCT01617083 Phase 2 Azithromycin;Placebo
6 Prevalence and Clinical Significance of Co-infection of Mycoplasma Pneumoniae in Patients With Pulmonary Tuberculosis Unknown status NCT00926601
7 Effectiveness Study of Integrative Treatment for Pediatric Community Acquired Pneumonia Unknown status NCT02362906 Not Applicable Xiyanping injection;wind-heat formula granules;phlegm-heat formula granules;Fu-xiong San;second generation cephalosporin;Erythromycin;Azithromycin
8 Randomized Controlled Trial of Doxycycline to Prevent Acquisition of Mycoplasma Pneumoniae in an Outbreak Setting Completed NCT00207584 Not Applicable Doxycycline treatment
9 Detection of Mycoplasma Pneumoniae Completed NCT02511262
10 The Optimization of Mycoplasm Pneumonia Antibiotic Therapy Completed NCT01259141 Not Applicable Moxifloxacin;Cephalosporins and azithromycin
11 Chlamydia and Mycoplasma in Coronary Artery Disease Completed NCT00561028
12 Etiology of Community Acquired Pneumonia Completed NCT00471757
13 Microbiologic Findings of Acute Facial Palsy in Children Completed NCT01537952
14 Treatment of Macrolide-resistant Mycoplasma Pneumoniae Recruiting NCT03530319 Not Applicable Doxycycline;Azithromycin
15 Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP) Recruiting NCT02303587 Not Applicable methylprednisolone
16 Assessment of Pharyngeal Carriage of Microorganisms Responsible for Transmissible Acute Respiratory Infections in HAJJ Pilgrims. Recruiting NCT02868541
17 Etiology Study of Kawasaki Disease Recruiting NCT00154596
18 DiagNostic Study of Low-dose CT and multipleX PCR on Antibiotic Treatment and Outcome of Community-Acquired Pneumonia Recruiting NCT03360851 Not Applicable
19 Comparative Autoantibody and Immunologic Cell Marker Study Enrolling by invitation NCT02422875
20 A Molecular Toolkit for the Microbial Investigation of Severe Community Acquired Pneumonia Not yet recruiting NCT02963142
21 Methylprednisolone Pulse Macrolide Therapy for Refractory Mycoplasma Pneumoniae Pneumonia in Children Terminated NCT01217099 Not Applicable methylprednisolone;azithromycin
22 Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For CAP Withdrawn NCT01662258 Not Applicable

Search NIH Clinical Center for Mycoplasmal Pneumonia

Genetic Tests for Mycoplasmal Pneumonia

Anatomical Context for Mycoplasmal Pneumonia

MalaCards organs/tissues related to Mycoplasmal Pneumonia:

41
Testes, Lung, Heart

Publications for Mycoplasmal Pneumonia

Articles related to Mycoplasmal Pneumonia:

(show top 50) (show all 72)
# Title Authors Year
1
Reply to 'Influenza follicles and their buds as early diagnostic markers of influenza: typical images' and demonstration of lymphoid follicles in the posterior pharyngeal walls of patients with mycoplasmal pneumonia. ( 29440479 )
2018
2
Determinants for swine mycoplasmal pneumonia reproduction under experimental conditions: A systematic review and recursive partitioning analysis. ( 28742802 )
2017
3
Effects of mycoplasmal pneumonia of swine (MPS) lung lesion-selected Landrace pigs on MPS resistance and immune competence in three-way crossbred pigs. ( 27612216 )
2016
4
Induction of mycoplasmal pneumonia in experimentally infected pigs by means of different inoculation routes. ( 27160189 )
2016
5
Ameliorative effects of Qingfei Tongluo formula on experimental mycoplasmal pneumonia in mice. ( 26590157 )
2016
6
Association of swine leukocyte antigen class II haplotypes and immune-related traits in a swine line selected for resistance to mycoplasmal pneumonia. ( 27638117 )
2016
7
Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions in Large White pigs selected for higher peripheral blood immune capacity. ( 26388420 )
2015
8
Correlated responses of respiratory disease and immune capacity traits of Landrace pigs selected for Mycoplasmal pneumonia of swine (MPS) lesion. ( 26608237 )
2015
9
Composite factors, including mycoplasmal pneumonia, hypersensitivity syndrome, and medicine, leading to bronchiolitis obliterans in a school-age child. ( 25022946 )
2014
10
Evaluation of recombinant Mycoplasma hyopneumoniae P97/P102 paralogs formulated with selected adjuvants as vaccines against mycoplasmal pneumonia in pigs. ( 24930717 )
2014
11
Impact of bacterial and viral coinfection on mycoplasmal pneumonia in childhood community-acquired pneumonia. ( 23927825 )
2013
12
Genetic selection for resistance to mycoplasmal pneumonia of swine (MPS) in the Landrace line influences the expression of soluble factors in blood after MPS vaccine sensitization. ( 24329865 )
2013
13
Mycoplasma pneumoniae extract induces an IL-17-associated inflammatory reaction in murine lung: implication for mycoplasmal pneumonia. ( 23001692 )
2013
14
Immunological characterization of peripheral blood leukocytes using vaccine for mycoplasmal pneumonia of swine (MPS) in swine line selected for resistance to MPS. ( 23607374 )
2013
15
Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal pneumonia in pigs after experimental challenge with two field isolates. ( 22863144 )
2012
16
Recognizing and preventing Mycoplasmal pneumonia. ( 20164718 )
2010
17
Effectiveness of coupled administration of Bioimmuno immunomodulator and Respisure One vaccine in the prophylaxis of mycoplasmal pneumonia of swine. ( 20731188 )
2010
18
Indices of non-specific and specific humoral immunity in pigs immunomodulated with the Bioimmuno preparation and/or immunised with the Respisure One vaccine against mycoplasmal pneumonia of swine. ( 21033558 )
2010
19
Oral vaccination against mycoplasmal pneumonia of swine using a live Erysipelothrix rhusiopathiae vaccine strain as a vector. ( 19433128 )
2009
20
Mycoplasmal pneumonia proceeding acute focal bacterial nephritis. ( 18793558 )
2008
21
[Serum levels of IFN-gamma and IL-4 in children with Mycoplasmal pneumonia at the acute phase]. ( 17052393 )
2006
22
Vaccine efficacy of the attenuated Erysipelothrix rhusiopathiae YS-19 expressing a recombinant protein of Mycoplasma hyopneumoniae P97 adhesin against mycoplasmal pneumonia of swine. ( 12531653 )
2003
23
Reduction of economic losses caused by mycoplasmal pneumonia of pigs by vaccination with Respisure and by Tiamutin treatment. ( 14516155 )
2003
24
Clinical efficacy of sparfloxacin in mycoplasmal pneumonia: a pilot study. ( 18370484 )
1998
25
Gene amplification (PCR) to detect and differentiate mycoplasmas in porcine mycoplasmal pneumonia. ( 9418066 )
1997
26
Mycoplasmal pneumonia in pigs in Croatia: first evaluation of a vaccine in fattening pigs. ( 9055454 )
1996
27
Recombinant 46-kilodalton surface antigen (P46) of Mycoplasma hyopneumoniae expressed in Escherichia coli can be used for early specific diagnosis of mycoplasmal pneumonia of swine by enzyme-linked immunosorbent assay. ( 7751376 )
1995
28
Mediastinal lymphadenopathy in mycoplasmal pneumonia. ( 8192050 )
1994
29
Seroepidemiology of mycoplasmal pneumonia of swine in Japan as surveyed by an enzyme-linked immunosorbent assay. ( 8451831 )
1993
30
Mycoplasmal pneumonia. Are you thinking of atypical presentations? ( 2235794 )
1990
31
Evaluation of tiamulin for treatment of mycoplasmal pneumonia in swine. ( 3170319 )
1988
32
Uncommon presentation of a common infection: mycoplasmal pneumonia. ( 3372204 )
1988
33
Mycoplasmal pneumonia--review of 202 hospitalized cases in Tokai University Hospital from 1975 to 1987. ( 3075822 )
1988
34
Cross-reactions between Mycoplasma hyopneumoniae and Mycoplasma flocculare--practical implications for the serodiagnosis of mycoplasmal pneumonia of swine. ( 3667232 )
1987
35
Community acquired mycoplasmal pneumonia. ( 3423800 )
1987
36
Immunoglobulin M rheumatoid factor in patients with mycoplasmal pneumonia. ( 3789522 )
1986
37
Mycoplasmal pneumonia in children. ( 3564543 )
1986
38
A case of mycoplasmal pneumonia secondary to measles pneumonia. With some observations on 20 hospitalized patients with mycoplasmal pneumonia in 1984. ( 4066902 )
1985
39
Evaluation of the indirect hemagglutination assay as a practical serodiagnostic test for mycoplasmal pneumonia of swine. ( 6433540 )
1984
40
Mycoplasmal pneumonia. Three severe cases of a common infection. ( 6494082 )
1984
41
Evaluation of criteria for the postmortem diagnosis of mycoplasmal pneumonia of swine. ( 6434167 )
1984
42
Circulating immune complexes in patients with mycoplasmal pneumonia. ( 6486561 )
1984
43
Mycoplasmal pneumonia associated with mesangiocapillary glomerulonephritis type II (dense deposit disease). ( 6516912 )
1984
44
Diagnosis of mycoplasmal pneumonia of swine: sequential study by direct immunofluorescence. ( 24049896 )
1984
45
Tiamulin feed medication for the maintenance of weight gains in the presence of mycoplasmal pneumonia in swine. ( 6674286 )
1983
46
Clinical features of mycoplasmal pneumonia in adults. ( 6679146 )
1983
47
Comparison of manually performed Microtiter plate and semiautomated (cuvette) indirect enzyme-linked immunosorbent assays for the serodiagnosis of mycoplasmal pneumonia of swine. ( 6354018 )
1983
48
Lung function in adults with mycoplasmal pneumonia. ( 7069939 )
1982
49
Mycoplasmal pneumonia and adult respiratory distress syndrome: a complication to be recognized. ( 7241615 )
1981
50
Evaluation of diagnostic procedures for detection of mycoplasmal pneumonia of swine. ( 447548 )
1979

Variations for Mycoplasmal Pneumonia

Expression for Mycoplasmal Pneumonia

Search GEO for disease gene expression data for Mycoplasmal Pneumonia.

Pathways for Mycoplasmal Pneumonia

Pathways related to Mycoplasmal Pneumonia according to GeneCards Suite gene sharing:

(show all 21)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.18 IFNG IL4
2 12.11 IFNG IL4
3
Show member pathways
12.05 IFNG IL4
4
Show member pathways
11.99 IFNG IL4
5
Show member pathways
11.97 IFNG IL4
6
Show member pathways
11.88 IFNG IL4
7
Show member pathways
11.87 IFNG IL4
8
Show member pathways
11.8 IFNG IL4
9
Show member pathways
11.73 IFNG IL4
10
Show member pathways
11.61 IFNG IL4
11 11.57 IFNG IL4
12 11.54 IFNG IL4
13
Show member pathways
11.51 IFNG IL4
14 11.35 IFNG IL4
15 11.31 IFNG IL4
16
Show member pathways
11.25 IFNG IL4
17 10.98 IFNG IL4
18 10.78 IFNG IL4
19 10.66 IFNG IL4
20 10.43 IFNG IL4
21 10.04 IFNG IL4

GO Terms for Mycoplasmal Pneumonia

Biological processes related to Mycoplasmal Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 8.62 IFNG IL4

Molecular functions related to Mycoplasmal Pneumonia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.62 IFNG IL4

Sources for Mycoplasmal Pneumonia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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