RCUD
MCID: MYL078
MIFTS: 13

Myelodysplastic Syndrome with Single Lineage Dysplasia (RCUD)

Categories: Rare diseases

Aliases & Classifications for Myelodysplastic Syndrome with Single Lineage Dysplasia

MalaCards integrated aliases for Myelodysplastic Syndrome with Single Lineage Dysplasia:

Name: Myelodysplastic Syndrome with Single Lineage Dysplasia 52 6
Refractory Cytopenia with Unilineage Dysplasia 52
Mds-Sld 52
Rcud 52

Classifications:



Summaries for Myelodysplastic Syndrome with Single Lineage Dysplasia

MalaCards based summary : Myelodysplastic Syndrome with Single Lineage Dysplasia, also known as refractory cytopenia with unilineage dysplasia, is related to neutropenia and thrombocytopenia. An important gene associated with Myelodysplastic Syndrome with Single Lineage Dysplasia is MSH6 (MutS Homolog 6). Affiliated tissues include bone, myeloid and bone marrow.

Related Diseases for Myelodysplastic Syndrome with Single Lineage Dysplasia

Diseases related to Myelodysplastic Syndrome with Single Lineage Dysplasia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 neutropenia 10.5
2 thrombocytopenia 10.5
3 refractory anemia 10.5
4 leukemia, acute myeloid 10.3
5 myelodysplastic syndrome 10.3

Graphical network of the top 20 diseases related to Myelodysplastic Syndrome with Single Lineage Dysplasia:



Diseases related to Myelodysplastic Syndrome with Single Lineage Dysplasia

Symptoms & Phenotypes for Myelodysplastic Syndrome with Single Lineage Dysplasia

Drugs & Therapeutics for Myelodysplastic Syndrome with Single Lineage Dysplasia

Search Clinical Trials , NIH Clinical Center for Myelodysplastic Syndrome with Single Lineage Dysplasia

Genetic Tests for Myelodysplastic Syndrome with Single Lineage Dysplasia

Anatomical Context for Myelodysplastic Syndrome with Single Lineage Dysplasia

MalaCards organs/tissues related to Myelodysplastic Syndrome with Single Lineage Dysplasia:

40
Bone, Myeloid, Bone Marrow

Publications for Myelodysplastic Syndrome with Single Lineage Dysplasia

Articles related to Myelodysplastic Syndrome with Single Lineage Dysplasia:

(show all 25)
# Title Authors PMID Year
1
Soluble NKG2D Ligands Are Potential Biomarkers and Sentinels of Immune-Mediated Bone Marrow Injury in Bone Marrow Failure Syndromes. 61
31216534 2020
2
Dyserythropoiesis evaluated by the RED score and hepcidin:ferritin ratio predicts response to erythropoietin in lower-risk myelodysplastic syndromes. 61
30287621 2019
3
Hospital-Based Case-Control Study of MDS Subtypes and Benzene Exposure in Shanghai. 61
28146040 2017
4
Monitoring of the Clonal Fraction by Fluorescence In Situ Hybridization in Myelodysplastic Syndrome: Comparison With International Working Group Treatment Response Criteria. 61
27232348 2016
5
Spectrum of the WHO Classification De Novo Myelodysplastic Syndrome: Experience from Southern Pakistan. 61
27039723 2016
6
[Serum Erythropoietin as Prognostic Marker in Myelodysplastic Syndromes]. 61
26849756 2015
7
Is chronic neutropenia always a benign disease? Evidences from a 5-year prospective study. 61
26066399 2015
8
In patients with myelodysplastic syndromes with del(5q), factors other than age and sex contribute to the prognostic advantage, which diminishes over time. 61
25960152 2015
9
Interobserver variance in myelodysplastic syndromes with less than 5 % bone marrow blasts: unilineage vs. multilineage dysplasia and reproducibility of the threshold of 2 % blasts. 61
25387664 2015
10
[Analysis of the karyotype abnormalities and its prognostic in 298 patients with myelodysplastic syndrome]. 61
25916290 2015
11
Refractory thrombocytopenia and neutropenia: a diagnostic challenge. 61
25745545 2015
12
Late hematological improvement of myelodysplastic syndrome following treatment with 5-azacitidine therapy. 61
25274238 2014
13
Increased plasma thrombopoietin levels in patients with myelodysplastic syndrome: a reliable marker for a benign subset of bone marrow failure. 61
23403320 2013
14
[Myelodysplastic syndrome classification]. 61
23587576 2013
15
Single nucleotide polymorphism array-based karyotyping in acute myeloid leukemia or myelodysplastic syndrome with trisomy 8 as the sole chromosomal abnormality. 61
23208021 2013
16
Inter-observer variance with the diagnosis of myelodysplastic syndromes (MDS) following the 2008 WHO classification. 61
22948274 2013
17
Prediction of progression from refractory cytopenia with unilineage dysplasia by analysis of bone marrow blast cell composition. 61
22706533 2012
18
NAD(P)H: quinone oxidoreductase 1 deficiency conjoint with marginal vitamin C deficiency causes cigarette smoke induced myelodysplastic syndromes. 61
21655231 2011
19
Recent advances in the diagnosis and classification of myeloid neoplasms--comments on the 2008 WHO classification. 61
20626469 2010
20
Differences in the distribution of subtypes according to the WHO classification 2008 between Japanese and German patients with refractory anemia according to the FAB classification in myelodysplastic syndromes. 61
20022110 2010
21
[Value of imprint in bone marrow morphological examination]. 61
20973233 2010
22
Refractory cytopenia with unilineage dysplasia: analysis of prognostic factors and survival in 126 patients. 61
20302387 2010
23
Integrating WHO 2001-2008 criteria for the diagnosis of Myelodysplastic Syndrome (MDS): a case-case analysis of benzene exposure. 61
19941839 2010
24
Myelodysplastic syndromes/neoplasms: recent classification system based on World Health Organization Classification of Tumors - International Agency for Research on Cancer for Hematopoietic and Lymphoid Tissues. 61
22282696 2010
25
[Classification of myeloid leukemias]. 61
19860179 2009

Variations for Myelodysplastic Syndrome with Single Lineage Dysplasia

ClinVar genetic disease variations for Myelodysplastic Syndrome with Single Lineage Dysplasia:

6 ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 MSH6 NM_000179.2(MSH6):c.3961A>G (p.Arg1321Gly)SNV Conflicting interpretations of pathogenicity 89490 rs41295278 2:48033750-48033750 2:47806611-47806611

Expression for Myelodysplastic Syndrome with Single Lineage Dysplasia

Search GEO for disease gene expression data for Myelodysplastic Syndrome with Single Lineage Dysplasia.

Pathways for Myelodysplastic Syndrome with Single Lineage Dysplasia

GO Terms for Myelodysplastic Syndrome with Single Lineage Dysplasia

Sources for Myelodysplastic Syndrome with Single Lineage Dysplasia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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