MCID: MYL003
MIFTS: 52

Myeloid Sarcoma

Categories: Blood diseases, Bone diseases, Cancer diseases, Immune diseases, Nephrological diseases, Rare diseases

Aliases & Classifications for Myeloid Sarcoma

MalaCards integrated aliases for Myeloid Sarcoma:

Name: Myeloid Sarcoma 12 53 59 15
Granulocytic Sarcoma 12 53 59 73
Extramedullary Myeloid Tumor 12 53 59
Chloroma 12 53 59
Sarcoma, Granulocytic 76
Sarcoma Granulocytic 55
Sarcoma, Myeloid 44

Characteristics:

Orphanet epidemiological data:

59
myeloid sarcoma
Inheritance: Not applicable; Age of onset: All ages;

Classifications:



External Ids:

Disease Ontology 12 DOID:8683
ICD10 33 C92.3 C92.30
ICD9CM 35 205.3
MeSH 44 D023981
NCIt 50 C3520 C35815
SNOMED-CT 68 35287006 94719007
Orphanet 59 ORPHA86850
UMLS via Orphanet 74 C0152276
MESH via Orphanet 45 D023981
ICD10 via Orphanet 34 C92.3
UMLS 73 C0152276

Summaries for Myeloid Sarcoma

NIH Rare Diseases : 53 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.Orpha Number: 86850Disease definitionMyeloid sarcoma is a rare solid tumor of the myelogenous cells occurring in an extramedullary site.EpidemiologyThe exact prevalence is unknown.Clinical descriptionThe clinical presentation depends on the site of involvement. Commonly involved sites of occurrence include the subperiosteal bone structures of the skull, paranasal sinuses, sternum, ribs, vertebrae, pelvis, as well as the lymph nodes and skin. Rare sites include the pancreas, heart, brain, mouth, breast, gastrointestinal and biliary tract, prostate, urinary bladder and gynecologic tract.Visit the Orphanet disease page for more resources.

MalaCards based summary : Myeloid Sarcoma, also known as granulocytic sarcoma, is related to myeloid leukemia and acute myeloblastic leukemia with maturation. An important gene associated with Myeloid Sarcoma is MPO (Myeloperoxidase), and among its related pathways/superpathways are NF-kappaB Signaling and Transcriptional misregulation in cancer. The drugs Fludarabine and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include myeloid, bone and breast, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 76 A myeloid sarcoma (chloroma, granulocytic sarcoma,extramedullary myeloid tumor), is a solid tumor... more...

Related Diseases for Myeloid Sarcoma

Diseases related to Myeloid Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 209)
# Related Disease Score Top Affiliating Genes
1 myeloid leukemia 30.9 FLT3 KIT NPM1
2 acute myeloblastic leukemia with maturation 30.0 FLT3 KIT NPM1
3 acute myeloid leukemia with t(8;21)(q22;q22) translocation 29.8 FLT3 KIT
4 lymphocytic leukemia 29.7 DNTT KMT2A PAX5
5 dendritic cell tumor 29.7 DNTT MPO PTPRC
6 blastic plasmacytoid dendritic cell 29.6 NCAM1 NPM1
7 leukemia, acute monocytic 29.6 KMT2A MPO
8 leukemia, chronic myeloid 29.5 DNTT FLT3 KIT KMT2A MPO
9 acute biphenotypic leukemia 29.5 DNTT KMT2A MPO
10 lymphoblastic lymphoma 29.4 DNTT KMT2A MPO PTPRC
11 lymphoma, hodgkin, classic 29.4 PAX5 PTPRC
12 myeloma, multiple 29.4 KIT NCAM1 PTPRC
13 myelodysplastic syndrome 29.3 ANPEP DNTT FLT3 KIT KMT2A NPM1
14 acute promyelocytic leukemia 29.3 ANPEP FLT3 MPO NCAM1 NPM1 PTPRC
15 leukemia, chronic lymphocytic 29.3 ANPEP DNTT PAX5 PTPRC
16 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 29.2 DNTT FLT3 KIT KMT2A MPO
17 ewing sarcoma 29.2 DNTT KIT NCAM1 PTPRC
18 leukemia, acute myeloid 29.2 ANPEP DNTT FLT3 KIT KMT2A MPO
19 precursor t-cell acute lymphoblastic leukemia 28.9 ANPEP DNTT FLT3 KMT2A MPO
20 leukemia, acute lymphoblastic 28.9 ANPEP DNTT FLT3 KMT2A PAX5
21 acute leukemia 28.8 ANPEP DNTT FLT3 KIT KMT2A MPO
22 sarcoma 11.0
23 leukemia 10.6
24 spindle cell sarcoma 10.3
25 acute myeloid leukemia with minimal differentiation 10.2 FLT3 MPO
26 acute myeloblastic leukemia without maturation 10.2 FLT3 NPM1
27 lymphoma 10.2
28 chronic monocytic leukemia 10.2 MPO PTPRC
29 primary cutaneous anaplastic large cell lymphoma 10.2 NPM1 PTPRC
30 epidural neoplasm 10.1 DNTT PTPRC
31 photokeratitis 10.1 DNTT PTPRC
32 natural killer cell leukemia 10.1 MPO NCAM1
33 hodgkin's lymphoma, lymphocytic depletion 10.1 PAX5 PTPRC
34 brain sarcoma 10.1
35 tetrasomy 21 10.1 ANPEP DNTT
36 malignant leydig cell tumor 10.1 KIT PAX5
37 anterior scleritis 10.1 MPO NCAM1
38 chronic eosinophilic leukemia 10.1 FLT3 KIT
39 extracutaneous mastocytoma 10.1 KIT PTPRC
40 conventional fibrosarcoma 10.1 KIT PTPRC
41 testicular infarct 10.1 KIT PTPRC
42 8p11 myeloproliferative syndrome 10.1 FLT3 KIT
43 radiculopathy 10.1
44 gastric small cell carcinoma 10.1 NCAM1 PTPRC
45 cutaneous ganglioneuroma 10.1 KIT NCAM1
46 core binding factor acute myeloid leukemia 10.1 FLT3 KIT
47 pediatric lymphoma 10.1 DNTT NCAM1
48 mediastinal cancer 10.0 KIT NCAM1
49 angiomyoma 10.0 KIT NCAM1
50 helsmoortel-van der aa syndrome 10.0 KIT NCAM1

Graphical network of the top 20 diseases related to Myeloid Sarcoma:



Diseases related to Myeloid Sarcoma

Symptoms & Phenotypes for Myeloid Sarcoma

GenomeRNAi Phenotypes related to Myeloid Sarcoma according to GeneCards Suite gene sharing:

26 (show all 31)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 10.06 MPO
2 Increased shRNA abundance (Z-score > 2) GR00366-A-102 10.06 DNTT FLT3 KIT
3 Increased shRNA abundance (Z-score > 2) GR00366-A-115 10.06 FLT3
4 Increased shRNA abundance (Z-score > 2) GR00366-A-120 10.06 FLT3
5 Increased shRNA abundance (Z-score > 2) GR00366-A-121 10.06 FLT3
6 Increased shRNA abundance (Z-score > 2) GR00366-A-122 10.06 FLT3
7 Increased shRNA abundance (Z-score > 2) GR00366-A-123 10.06 DNTT FLT3
8 Increased shRNA abundance (Z-score > 2) GR00366-A-126 10.06 MPO
9 Increased shRNA abundance (Z-score > 2) GR00366-A-138 10.06 DNTT
10 Increased shRNA abundance (Z-score > 2) GR00366-A-151 10.06 DNTT
11 Increased shRNA abundance (Z-score > 2) GR00366-A-152 10.06 KIT
12 Increased shRNA abundance (Z-score > 2) GR00366-A-157 10.06 DNTT KIT MPO
13 Increased shRNA abundance (Z-score > 2) GR00366-A-16 10.06 DNTT
14 Increased shRNA abundance (Z-score > 2) GR00366-A-163 10.06 FLT3
15 Increased shRNA abundance (Z-score > 2) GR00366-A-170 10.06 KIT
16 Increased shRNA abundance (Z-score > 2) GR00366-A-176 10.06 MPO
17 Increased shRNA abundance (Z-score > 2) GR00366-A-182 10.06 DNTT
18 Increased shRNA abundance (Z-score > 2) GR00366-A-186 10.06 MPO
19 Increased shRNA abundance (Z-score > 2) GR00366-A-197 10.06 DNTT
20 Increased shRNA abundance (Z-score > 2) GR00366-A-25 10.06 FLT3
21 Increased shRNA abundance (Z-score > 2) GR00366-A-29 10.06 MPO
22 Increased shRNA abundance (Z-score > 2) GR00366-A-30 10.06 KIT
23 Increased shRNA abundance (Z-score > 2) GR00366-A-36 10.06 MPO
24 Increased shRNA abundance (Z-score > 2) GR00366-A-42 10.06 KIT
25 Increased shRNA abundance (Z-score > 2) GR00366-A-57 10.06 MPO
26 Increased shRNA abundance (Z-score > 2) GR00366-A-7 10.06 MPO
27 Increased shRNA abundance (Z-score > 2) GR00366-A-70 10.06 FLT3 MPO
28 Increased shRNA abundance (Z-score > 2) GR00366-A-73 10.06 DNTT
29 Increased shRNA abundance (Z-score > 2) GR00366-A-85 10.06 KIT
30 Increased shRNA abundance (Z-score > 2) GR00366-A-9 10.06 KIT
31 Increased shRNA abundance (Z-score > 2) GR00366-A-99 10.06 KIT

MGI Mouse Phenotypes related to Myeloid Sarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.91 ANPEP DNTT FLT3 KIT KMT2A MPO
2 cellular MP:0005384 9.87 FLT3 KIT KMT2A NCAM1 NPM1 PAX5
3 cardiovascular system MP:0005385 9.85 ANPEP DNTT KIT KMT2A MPO NPM1
4 immune system MP:0005387 9.81 ANPEP DNTT FLT3 KIT KMT2A MPO
5 mortality/aging MP:0010768 9.56 FLT3 KIT KMT2A MPO NCAM1 NPM1
6 neoplasm MP:0002006 9.1 FLT3 KIT KMT2A NPM1 PAX5 PTPRC

Drugs & Therapeutics for Myeloid Sarcoma

Drugs for Myeloid Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 106)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fludarabine Approved Phase 3,Phase 2,Phase 1 75607-67-9, 21679-14-1 30751
2
Cyclophosphamide Approved, Investigational Phase 3,Phase 2 6055-19-2, 50-18-0 2907
3
Aldesleukin Approved Phase 3,Phase 2 85898-30-2, 110942-02-4
4
leucovorin Approved Phase 3 58-05-9 6006 143
5
Lenograstim Approved, Investigational Phase 3,Phase 2,Phase 1 135968-09-1
6
Etoposide Approved Phase 3 33419-42-0 36462
7
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
8
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
9
Hydrocortisone Approved, Vet_approved Phase 3 50-23-7 5754
10
Daunorubicin Approved Phase 3 20830-81-3 30323
11
Methotrexate Approved Phase 3 59-05-2, 1959-05-2 126941
12
Busulfan Approved, Investigational Phase 3 55-98-1 2478
13
Cytarabine Approved, Investigational Phase 3,Phase 2,Phase 1 147-94-4 6253
14
Thioguanine Approved Phase 3 154-42-7 2723601
15
Idarubicin Approved Phase 3,Phase 2 58957-92-9 42890
16
Hydrocortisone acetate Approved, Vet_approved Phase 3 50-03-3
17
Darbepoetin alfa Approved, Investigational Phase 3 11096-26-7, 209810-58-2
18
Mitoxantrone Approved, Investigational Phase 3,Phase 2 65271-80-9 4212
19
Bortezomib Approved, Investigational Phase 3 179324-69-7 387447 93860
20
Nicotinamide Approved, Investigational Phase 3 98-92-0 936
21
Sorafenib Approved, Investigational Phase 3 284461-73-0 216239 406563
22
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
23
Niacin Approved, Investigational, Nutraceutical Phase 3 59-67-6 938
24 Anti-Infective Agents Phase 3,Phase 2,Phase 1
25 Aspartic Acid Phase 3
26 Anti-HIV Agents Phase 3,Phase 2
27 Vidarabine Phosphate Phase 3,Phase 1
28 Antirheumatic Agents Phase 3,Phase 2
29 Hydrocortisone-17-butyrate Phase 3
30 Antineoplastic Agents, Phytogenic Phase 3
31 Alkylating Agents Phase 3,Phase 2
32 Analgesics, Non-Narcotic Phase 3,Phase 2
33 Dermatologic Agents Phase 3
34 N-Methylaspartate Phase 3
35 Folic Acid Antagonists Phase 3
36 Antiemetics Phase 3
37 Immunologic Factors Phase 3,Phase 2,Phase 1
38 Gastrointestinal Agents Phase 3
39 Hormone Antagonists Phase 3
40 Vitamin B Complex Phase 3
41 Etoposide phosphate Phase 3
42 Vitamin B9 Phase 3
43 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
44 Analgesics Phase 3,Phase 2
45 glucocorticoids Phase 3
46 Peripheral Nervous System Agents Phase 3,Phase 2
47 Hormones Phase 3
48 Autonomic Agents Phase 3
49 Anti-Retroviral Agents Phase 3,Phase 2
50 Folate Phase 3

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome Completed NCT00002798 Phase 3 asparaginase;daunorubicin hydrochloride;fludarabine phosphate;therapeutic hydrocortisone;cytarabine;idarubicin;dexamethasone;thioguanine;etoposide;methotrexate;cyclophosphamide;busulfan
2 Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML Completed NCT00574873 Phase 3 Bosutinib;imatinib
3 Darbepoetin Alfa in Patients With Anemic Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) Completed NCT01362140 Phase 3 Darbepoetin alfa;Placebo
4 Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia Active, not recruiting NCT01371981 Phase 3 Asparaginase;Bortezomib;Cytarabine;Daunorubicin Hydrochloride;Etoposide;Mitoxantrone Hydrochloride;Sorafenib Tosylate
5 CIP-613, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Granulocytic Sarcoma Recruiting NCT02484391 Phase 2 6,8-Bis(benzylthio)octanoic Acid;Cytarabine;Mitoxantrone Hydrochloride
6 MG4101 for Refractory or Relapsed AML Recruiting NCT03349502 Phase 2 MG4101
7 Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation Recruiting NCT02790515 Phase 2 Anti-thymocyte globulin (rabbit);Blinatumomab;Cyclophosphamide;Fludarabine;G-CSF;Melphalan;Mesna;Rituximab;Tacrolimus;Thiotepa;Sirolimus
8 Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancers Recruiting NCT03589729 Phase 2 Cladribine;Cytarabine;Dexrazoxane Hydrochloride;Gemtuzumab Ozogamicin;Idarubicin
9 Vosaroxin and Infusional Cytarabine in Treating Patients With Untreated Acute Myeloid Leukemia Suspended NCT02658487 Phase 2 Cytarabine;Vosaroxin
10 Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation Terminated NCT02259348 Phase 2 Cyclophosphamide;Fludarabine;Melphalan;Thiotepa;Rituximab
11 Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia Withdrawn NCT02791919 Phase 1 Cytarabine;Fludarabine Phosphate;WEE1 Inhibitor AZD1775
12 PET-CT in AML for Detection of Extramedullary AML Manifestations Completed NCT01278069
13 Central Nervous System (CNS) Involvement in Acute Myeloid Leukemia (AML) Not yet recruiting NCT03410407

Search NIH Clinical Center for Myeloid Sarcoma

Cochrane evidence based reviews: sarcoma, myeloid

Genetic Tests for Myeloid Sarcoma

Anatomical Context for Myeloid Sarcoma

MalaCards organs/tissues related to Myeloid Sarcoma:

41
Myeloid, Bone, Breast, Bone Marrow, Skin, Brain, Lymph Node

Publications for Myeloid Sarcoma

Articles related to Myeloid Sarcoma:

(show top 50) (show all 1127)
# Title Authors Year
1
RTK-RAS pathway mutation is enriched in myeloid sarcoma. ( 29789584 )
2018
2
Coexistent cutaneous myeloid sarcoma in a patient with invasive papillary carcinoma of thyroid - A rare presentation. ( 29855456 )
2018
3
Activity of decitabine in pericardial myeloid sarcoma. ( 29779081 )
2018
4
A Rare Case of Relapsed Pediatric Acute Promyelocytic Leukemia with Skin Involvement by Myeloid Sarcoma. ( 29650946 )
2018
5
A unique clinical presentation of de novo acute promyelocytic leukemia as a myeloid sarcoma of the breast. ( 29931624 )
2018
6
Intermediate dose cytarabine in treatment myeloid sarcoma of the bilateral breast after allogeneic stem cell transplantation: A case report and literature review. ( 29893346 )
2018
7
Detection of prognostically relevant mutations and translocations in myeloid sarcoma by next generation sequencing. ( 28633614 )
2018
8
Loss of RKIP is a frequent event in myeloid sarcoma and promotes leukemic tissue infiltration. ( 29295844 )
2018
9
Myeloid sarcoma involving the greater wing of the sphenoid bone and additional skeletal sites presenting with unilateral proptosis and fevers. ( 29557698 )
2018
10
Connecting the Dots: A Case of Myeloid Sarcoma. ( 29729239 )
2018
11
Myeloid Sarcoma Presented as Generalized Lymphadenopathy: Mimicking Malignant Lymphoma. ( 29398826 )
2018
12
Expression of programmed death ligand 1 is associated with poor prognosis in myeloid sarcoma patients. ( 29602174 )
2018
13
Clinicopathological characteristics of de novo and secondary myeloid sarcoma: A monocentric retrospective study. ( 29532520 )
2018
14
A Rare Cause of Paraplegia: Myeloid Sarcoma. ( 29393854 )
2018
15
Peritoneal Myeloid Sarcoma in a Patient Treated for a Testicular Seminoma. ( 29955031 )
2018
16
Clinical characteristics of pediatric patients with myeloid sarcoma without bone marrow involvement in Japan. ( 29971602 )
2018
17
Primary Myeloid Sarcoma of the Prostate: A Case Report and Literature Review. ( 29854498 )
2018
18
Sacral Myeloid Sarcoma Manifesting as Radiculopathy in a Pediatric Patient: An Unusual Form of Myeloid Leukemia Relapse. ( 29888021 )
2018
19
Myeloid sarcoma of the small intestine in a patient without overt acute myeloid leukaemia: a challenging diagnosis of a rare condition. ( 29848520 )
2018
20
Myeloid sarcoma as a simulator of advanced ovarian cancer: A case report. ( 29666016 )
2018
21
Case Report of Myeloid Sarcoma Masquerading as In-Transit Metastasis at a Previous Melanoma Site: Avoiding a Diagnostic Pitfall. ( 29863571 )
2018
22
Myeloid Sarcoma Predicts Superior Outcome in Pediatric AML; Can Cytogenetics Solve the Puzzle? ( 29680411 )
2018
23
Isolated Pancreatic Myeloid Sarcoma Associated with t(8;21)/RUNX1-RUNX1T1 Rearrangement. ( 29151502 )
2018
24
Myeloid Sarcoma after Allogenic Stem Cell Transplantation for Acute Myeloid Leukemia: Successful Consolidation Treatment Approaches in Two Patients. ( 29682375 )
2018
25
Role of Positron Emission Tomography Imaging in Myeloid Sarcoma. ( 29430131 )
2018
26
Myeloid sarcoma with megakaryoblastic differentiation presenting as a breast mass. ( 29684340 )
2018
27
Case report: Purulent transformation of granulocytic sarcoma: An unusual pattern of differentiation in acute promyelocytic leukemia. ( 29465554 )
2018
28
Successful Treatment of Relapsed Pediatric Acute Myeloid Leukemia Presenting as Central Nervous System Myeloid Sarcoma: A Single-Institution Case Series. ( 30543582 )
2018
29
A Case of Granulocytic Sarcoma or Extramedullary Acute Myelomonocytic Leukemia of the Gallbladder. ( 30352989 )
2018
30
Myeloid Sarcoma of the Paranasal Sinuses in a Patient with Acute Myeloid Leukemia. ( 30369515 )
2018
31
Intraoral granulocytic sarcoma as a manifestation of myelofibrosis: A case report and review of the literature. ( 30188579 )
2018
32
Mediastinal Myeloid Sarcoma with TP53 Mutation Preceding Acute Myeloid Leukemia with a PICALM-MLLT10 Fusion Gene. ( 30227397 )
2018
33
Myeloid sarcoma arising in malignant phyllodes tumour: clonal relationships revealed by comparative genome-wide analyses. ( 28211578 )
2018
34
A case of ureteral myeloid sarcoma post-renal transplantation. ( 29486724 )
2018
35
Myeloid sarcoma without circulating leukemia mimicking gastrointestinal malignancy and lymphoma. ( 30046410 )
2018
36
Obstructive jaundice caused by myeloid sarcoma in duodenal ampulla. ( 30253977 )
2018
37
Myeloid Sarcoma of Orbits: Effectiveness of a Low-Dose Radiation Regimen. ( 30271643 )
2018
38
Isolated myeloid sarcoma in the pancreas and orbit: A case report and review of literature. ( 30294614 )
2018
39
Acute myeloid leukaemia relapse presenting as cardiac myeloid sarcoma. ( 30389743 )
2018
40
Isolated Orbital Myeloid Sarcoma as a Therapy-related Myeloid Neoplasm. ( 30449814 )
2018
41
Primary Myeloid Sarcoma of the Breast: A Case Report and Review of Literature. ( 30464895 )
2018
42
Increased angiogenesis seems to correlate with inferior overall survival in myeloid sarcoma patients. ( 30509052 )
2018
43
A case of myeloid sarcoma presenting with an orbital mass, hearing loss, and multiple cranial neuropathies. ( 30511548 )
2018
44
A Lateral Neck Myeloid Sarcoma Presenting as Acute Otitis Externa. ( 30551696 )
2018
45
Primary granulocytic sarcoma presenting as a lumbar plexopathy in a nonleukemic patient. ( 30038120 )
2018
46
Granulocytic sarcoma and mediastinal germ cell tumor: A common cell of origin? ( 29913128 )
2018
47
An uncommon granulocytic sarcoma of the breast: a case report and literature review. ( 29983576 )
2018
48
Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature. ( 29642189 )
2018
49
Radiotherapy for isolated granulocytic sarcoma: Case report and review of literature. ( 29594235 )
2018
50
Fine-needle aspiration cytology of granulocytic sarcoma presenting as a breast lump - Report of a rare case with a comprehensive literature search. ( 29403218 )
2018

Variations for Myeloid Sarcoma

Expression for Myeloid Sarcoma

Search GEO for disease gene expression data for Myeloid Sarcoma.

Pathways for Myeloid Sarcoma

GO Terms for Myeloid Sarcoma

Cellular components related to Myeloid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasmic side of plasma membrane GO:0009898 8.96 KIT PTPRC
2 external side of plasma membrane GO:0009897 8.92 ANPEP KIT NCAM1 PTPRC

Biological processes related to Myeloid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.67 FLT3 KIT MPO NPM1
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.63 FLT3 KIT PTPRC
3 viral process GO:0016032 9.62 ANPEP FLT3 NCAM1 NPM1
4 MAPK cascade GO:0000165 9.61 FLT3 KIT NCAM1
5 T cell differentiation GO:0030217 9.48 KIT PTPRC
6 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 9.4 FLT3 KIT
7 positive regulation of MAPK cascade GO:0043410 9.33 FLT3 KIT PTPRC
8 embryonic hemopoiesis GO:0035162 9.26 KIT KMT2A
9 regulation of B cell receptor signaling pathway GO:0050855 8.96 PAX5 PTPRC
10 myeloid progenitor cell differentiation GO:0002318 8.62 FLT3 KIT

Molecular functions related to Myeloid Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.13 FLT3 KIT NCAM1
2 protein homodimerization activity GO:0042803 9.02 FLT3 KIT KMT2A NPM1 PTPRC

Sources for Myeloid Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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