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HAM
MCID: MYL057
MIFTS: 42

Myelopathy, Htlv-1-Associated (HAM)

Categories: Genetic diseases, Immune diseases, Infectious diseases, Neuronal diseases, Rare diseases, Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Myelopathy, Htlv-1-Associated

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MalaCards integrated aliases for Myelopathy, Htlv-1-Associated:

Name: Myelopathy, Htlv-1-Associated 57 55
Tropical Spastic Paraparesis 59 73
Human T-Lymphotropic Virus Type I-Associated Myelopathy/tropical Spastic Paraparesis 59
Human T-Lymphotropic Virus Type-1-Associated Myelopathy/tropical Spastic Paraparesis 59
Htlv-1-Associated Myelopathy/tropical Spastic Paraparesis 59
Familial Spastic Paraparesis, Htlv-1-Associated 57
Htlv-1 Associated Myelopathy 54
Htlv1-Associated Myelopathy 37
Ham/tsp 59
Ham 57
Tsp 59

Characteristics:

Orphanet epidemiological data:

59
tropical spastic paraparesis
Inheritance: Not applicable; Age of onset: Adult;

OMIM:

57
Inheritance:
possible genetic factors


Classifications:

MalaCards categories:
Global: Infectious diseases Rare diseases Genetic diseases
Anatomical: Neuronal diseases Skin diseases Immune diseases
See all MalaCards categories (disease lists)
ICD10: 34
Orphanet: 59  
Rare neurological diseases
Rare infectious diseases


External Ids:

OMIM 57 159580
Orphanet 59 ORPHA289326
UMLS via Orphanet 74 C0030481
ICD10 via Orphanet 34 G04.1
MedGen 42 C0030481
KEGG 37 H01724
SNOMED-CT via HPO 69 48522003 312444006 14648003
UMLS 73 C0030481
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Summaries for Myelopathy, Htlv-1-Associated

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NINDS : 54 For several decades the term “tropical spastic paraparesis” (TSP) has been used to describe a chronic and progressive disease of the nervous system that affects adults living in equatorial areas of the world and causes progressive weakness, stiff muscles, muscle spasms, sensory disturbance, and sphincter dysfunction. The cause of TSP was obscure until the mid-1980s, when an important association was established between the human retrovirus — human T-cell lymphotrophic virus type 1 (also known as HTLV-1) — and TSP. TSP is now called HTLV-1 associated myelopathy/ tropical spastic paraparesis or HAM/TSP. The HTLV-1 retrovirus is thought to cause at least 80 percent of the cases of HAM/TSP by impairing the immune system. In addition to neurological symptoms of weakness and muscle stiffness or spasms, in rare cases individuals with HAM/TSP also exhibit uveitis (inflammation of the uveal tract of the eye), arthritis (inflammation of one or more joints), pulmonary lymphocytic alveolitis (inflammation of the lung), polymyositis (an inflammatory muscle disease), keratoconjunctivitis sicca (persistent dryness of the cornea and conjunctiva), and infectious dermatitis (inflammation of the skin). The other serious complication of HTLV-1 infection is the development of adult T-cell leukemia or lymphoma. Nervous system and blood-related complications occur only in a very small proportion of infected individuals, while most remain largely without symptoms throughout their lives. The HTLV-1 virus is transmitted person-to-person via infected cells: breast-feeding by mothers who are seropositive (in other words, have high levels of virus antibodies in their blood), sharing infected needles during intravenous drug use, or having sexual relations with a seropositive partner. Less than 2 percent of HTLV-1 seropositive carriers will become HAM/TSP patients.

MalaCards based summary : Myelopathy, Htlv-1-Associated, also known as tropical spastic paraparesis, is related to htlv-1 associated myelopathy/tropical spastic paraparesis and tropical spastic paraparesis. An important gene associated with Myelopathy, Htlv-1-Associated is CNTN2 (Contactin 2), and among its related pathways/superpathways is Human T-cell leukemia virus 1 infection. The drugs Zidovudine and Lamivudine have been mentioned in the context of this disorder. Affiliated tissues include t cells, skin and lung, and related phenotypes are spastic paraparesis and myelopathy

Wikipedia : 76 Tropical spastic paraparesis (TSP), also called HTLV-I-associated myelopathy (HAM) or HTLV-I-associated... more...

Description from OMIM: 159580
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Related Diseases for Myelopathy, Htlv-1-Associated

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Diseases related to Myelopathy, Htlv-1-Associated via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 htlv-1 associated myelopathy/tropical spastic paraparesis 12.0
2 tropical spastic paraparesis 11.8
3 retrovirus-associated myelopathy 11.4
4 human t-cell leukemia virus type 1 11.4
5 autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasia 11.1
6 spastic paraparesis 10.7
7 leukemia 10.3
8 t-cell leukemia 10.3
9 vasculitis 10.2
10 polymyositis 10.2
11 adult t-cell leukemia 10.2
12 staphyloenterotoxemia 10.1
13 creutzfeldt-jakob disease 10.1
14 systemic lupus erythematosus 10.1
15 sexual disorder 10.1
16 cutaneous t cell lymphoma 10.1
17 sarcoma 10.1
18 lyme disease 10.1
19 interstitial cystitis 10.1
20 prostatitis 10.1
21 cystitis 10.1
22 malignant fibroxanthoma 10.1
23 neuroaxonal dystrophy 10.1
24 protein s deficiency 10.1
25 syphilis 10.1
26 pseudohypoparathyroidism 10.1
27 histiocytoma 10.1
28 folliculitis 10.1
29 fibrous histiocytoma 10.1
30 paraplegia 10.1
31 thyroiditis 10.1
32 lupus erythematosus 10.1
33 psoriasis 10.1
34 viral infectious disease 10.1
35 postpartum depression 10.1
36 quinquaud's decalvans folliculitis 10.1
37 syringohydromyelia 10.1
38 dysautonomia 10.1
39 encephalopathy 10.1
40 histiocytic sarcoma 10.1
41 paroxysmal nocturnal hemoglobinuria 10.0
42 hemoglobinuria 10.0
43 lepromatous leprosy 10.0
44 central nervous system leukemia 10.0
45 amyloidosis 10.0
46 amyotrophic lateral sclerosis 1 9.9
47 leukemia, acute myeloid 9.9
48 anxiety 9.9
49 pseudopseudohypoparathyroidism 9.9
50 hematopoietic stem cell transplantation 9.9

Graphical network of the top 20 diseases related to Myelopathy, Htlv-1-Associated:



Diseases related to Myelopathy, Htlv-1-Associated
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Symptoms & Phenotypes for Myelopathy, Htlv-1-Associated

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Symptoms via clinical synopsis from OMIM:

57
Neuro:
myelopathy
pyramidal signs
tropical spastic paraparesis
mild or no sensory disturbance

Lab:
anti-htlv-i antibodies in both serum and csf


Clinical features from OMIM:

159580

Human phenotypes related to Myelopathy, Htlv-1-Associated:

32
# Description HPO Frequency HPO Source Accession
1 spastic paraparesis 32 HP:0002313
2 myelopathy 32 HP:0002196
3 abnormal pyramidal sign 32 HP:0007256
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Drugs & Therapeutics for Myelopathy, Htlv-1-Associated

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Drugs for Myelopathy, Htlv-1-Associated (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 45)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Zidovudine Approved Phase 2, Phase 3,Early Phase 1 30516-87-1 35370
2
Lamivudine Approved, Investigational Phase 2, Phase 3 134678-17-4 60825
3
Miconazole Approved, Investigational, Vet_approved Phase 2, Phase 3 22916-47-8 4189
4
Valproic Acid Approved, Investigational Phase 3,Not Applicable 99-66-1 3121
5
Pentoxifylline Approved, Investigational Phase 3 6493-05-6 4740
6 Reverse Transcriptase Inhibitors Phase 2, Phase 3,Early Phase 1
7 Nucleic Acid Synthesis Inhibitors Phase 2, Phase 3,Early Phase 1
8 Anti-HIV Agents Phase 2, Phase 3,Early Phase 1
9 Antiviral Agents Phase 2, Phase 3,Early Phase 1
10 Anti-Retroviral Agents Phase 2, Phase 3,Early Phase 1
11 Anti-Infective Agents Phase 2, Phase 3,Phase 3,Early Phase 1
12 Antimetabolites Phase 2, Phase 3,Early Phase 1
13 Immunosuppressive Agents Phase 2, Phase 3
14 Calcineurin Inhibitors Phase 2, Phase 3
15 Antifungal Agents Phase 2, Phase 3
16 Immunologic Factors Phase 2, Phase 3
17 Dermatologic Agents Phase 2, Phase 3
18 Cyclosporins Phase 2, Phase 3
19 Antirheumatic Agents Phase 2, Phase 3
20 Psychotropic Drugs Phase 3,Not Applicable
21 GABA Agents Phase 3,Not Applicable
22 Central Nervous System Depressants Phase 3,Not Applicable
23 Antimanic Agents Phase 3,Not Applicable
24 Anticonvulsants Phase 3,Not Applicable
25 Tranquilizing Agents Phase 3,Not Applicable
26 Neurotransmitter Agents Phase 3,Not Applicable
27 Vasodilator Agents Phase 3
28 Phosphodiesterase Inhibitors Phase 3
29 Free Radical Scavengers Phase 3
30 Radiation-Protective Agents Phase 3
31 Protective Agents Phase 3
32 Platelet Aggregation Inhibitors Phase 3
33 Antioxidants Phase 3
34
Interferon beta-1a Approved, Investigational Phase 2 145258-61-3 6438354
35
Infliximab Approved Phase 2 170277-31-3
36 Interferon-beta Phase 2
37 interferons Phase 2
38 Adjuvants, Immunologic Phase 2
39 Gastrointestinal Agents Phase 2
40 Immunoglobulins Phase 1
41 Antibodies, Monoclonal Phase 1
42 Antibodies Phase 1
43 HIV Integrase Inhibitors Early Phase 1
44 Integrase Inhibitors Early Phase 1
45 Raltegravir Potassium Early Phase 1

Interventional clinical trials:

(show all 22)
# Name Status NCT ID Phase Drugs
1 MP Diagnostics HTLV Blot 2.4 Post-Market Clinical Study Completed NCT03226119 Phase 4
2 Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) Unknown status NCT01343355 Phase 2, Phase 3 Tamibarotene
3 Zidovudine Plus Lamivudine in HTLV-I-associated Myelopathy: a Randomised Trial Completed NCT00272480 Phase 2, Phase 3 Zidovudine/lamivudine
4 Ciclosporin in HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP) Completed NCT00773292 Phase 2, Phase 3 ciclosporin
5 Use Of Valproid Acid To Treat Tropical Spastic Paraparesis/HTLV-1-Associated Myelopathy (TSP/HAM) Completed NCT00681980 Phase 3 Valproic acid;costicosteroids;valproid acid plus corticosteroids
6 Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) Diseases Completed NCT01472263 Phase 3 Pentoxifylline;Placebo
7 A Study of KW-0761 in Subjects With HTLV-1 Associated Myelopathy (HAM) Active, not recruiting NCT03191526 Phase 3 KW-0761 0.3 mg/kg IV;Placebo (saline)
8 Recombinant Human Interferon Beta-1a (Avonex) for the Treatment of Patients With HTLV-1-Associated Myelopathy (HAM) Completed NCT00001785 Phase 2 Recombinant human interferon beta-1a
9 The HAM Infliximab Study Terminated NCT00823641 Phase 2 Infliximab
10 Immunotherapy of Natural Killer(NK) Cells in Human T Lymphotropic Virus Type 1(HTLV-1) Associated Myelopathy(HAM) Unknown status NCT02961712 Phase 1
11 Hu Mik-Beta-1 to Treat HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Completed NCT00076843 Phase 1 Hu MiK-Beta-1
12 Evaluation of the MP Diagnostics HTLV Blot 2.4 Unknown status NCT01467024
13 MRI Brain Studies in Patients With HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis Completed NCT00034723
14 A Study of Familial and Genetic Aspects of Adult T-Cell: Leukemia/Lymphoma , Tropical Spastic Paraparesis, and Infective Dermatitis Completed NCT00340821
15 Raltegravir for HAM/TSP Completed NCT01867320 Early Phase 1 Raltegravir
16 Urological Physical Therapy in HTLV-1 With Urinary Symptoms Completed NCT01651819 Not Applicable
17 Influence of IL28B Genetic Variation on the Phenotype Infection of HTLV-1 Completed NCT01754311
18 Assessment of Patients With Multiple Sclerosis (MS) Completed NCT00001156
19 Dual Algorithm Post Market Clinical Study Completed NCT03146013
20 Effect of Raltegravir in Patients With Acute Tropical Spastic Paraparesis - Human T-Lymphotropic Virus 1 Infection Recruiting NCT02655471 Early Phase 1 "Raltegravir" and "Zidovudine"
21 Evaluation of Patients With HAM/TSP Recruiting NCT00001778
22 Safety and Efficiency Study of Valproic Acid In HAM/TSP Terminated NCT00519181 Not Applicable Valproic Acid

Search NIH Clinical Center for Myelopathy, Htlv-1-Associated

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Genetic Tests for Myelopathy, Htlv-1-Associated

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Anatomical Context for Myelopathy, Htlv-1-Associated

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MalaCards organs/tissues related to Myelopathy, Htlv-1-Associated:

41
T Cells, Skin, Lung, Eye, Breast, Spinal Cord, Thyroid
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Publications for Myelopathy, Htlv-1-Associated

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Articles related to Myelopathy, Htlv-1-Associated:

(show top 50) (show all 434)
# Title Authors Year
1
Balance, functional mobility, and fall occurrence in patients with human T-cell lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis: a cross-sectional study. ( 29768548 )
2018
2
Role of Integrin Signaling Activation on the Development of Human T-Cell Leukemia VIrus-1 (HTLV-1)-Associated Myelopathy/Tropical Spastic Paraparesis: Its Relationship to HTLV-1-infected CD4+ T Cell Transmigrating Activity into the Tissues. ( 29400072 )
2018
3
Temporal trends in Human T-Lymphotropic virus 1 (HTLV-1) associated myelopathy/tropical spastic paraparesis (HAM/TSP) incidence in Martinique over 25 years (1986-2010). ( 29554087 )
2018
4
Early Juvenile HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP): Study of 25 Patients. ( 29912303 )
2018
5
Prosultiamine for treatment of lower urinary tract dysfunction accompanied by human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis. ( 28965354 )
2018
6
Proposal of Classification Criteria for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Disease Activity. ( 30090093 )
2018
7
Different roles of CXCR1 and CXCR2 in HTLV-1 carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. ( 30341468 )
2018
8
Interferon Lambda Family along with HTLV-1 Proviral Load, Tax, and HBZ Implicated in the Pathogenesis of Myelopathy/Tropical Spastic Paraparesis. ( 29990995 )
2018
9
Human T-Lymphotropic Virus-1-Associated Myelopathy/Tropical Spastic Paraparesis Is Associated With Sexual Dysfunction in Infected Women of Reproductive Age. ( 30181035 )
2018
10
Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil. ( 30466392 )
2018
11
Role of IL-21 in HTLV-1 infections with emphasis on HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). ( 28378248 )
2017
12
Modulatory effects of curcumin on apoptosis and cytotoxicity-related molecules in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. ( 27894665 )
2017
13
Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study. ( 28536850 )
2017
14
Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis. ( 28420387 )
2017
15
Evaluation of T Regulatory Lymphocytes Transcription Factors in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Patients. ( 28101786 )
2017
16
Clinical and laboratory features of HTLV-I asymptomatic carriers and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis from the Brazilian Amazon. ( 28380116 )
2017
17
Indigenous tropical spastic paraparesis in Madrid (Spain). Experience on screening of human T-lymphotropic virus. ( 26282070 )
2017
18
Multiple spotty lesions of the spinal cord in a Chinese patient with human T-lymphotropic virus type 1-associated myelopathy/tropical spastic paraparesis. ( 29292042 )
2017
19
The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis. ( 29202792 )
2017
20
Early Onset of HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) and Adult T-cell Leukemia/Lymphoma (ATL): Systematic Search and Review. ( 28582585 )
2017
21
IL17A Polymorphism Is Not Associated with Human T-Lymphotropic Virus 1-Associated Myelopathy/Tropical Spastic Paraparesis. ( 28410448 )
2017
22
Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). ( 28095504 )
2017
23
Mediators Go Together: High Production of CXCL9, CXCL10, IFN-γ, and TNF-α in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. ( 28648091 )
2017
24
The effect of HTLV-1 virulence factors (HBZ, Tax, proviral load), HLA class I and plasma neopterin on manifestation of HTLV-1 associated myelopathy tropical spastic paraparesis. ( 27845163 )
2017
25
Human T-Lymphotropic Virus Type-1-Associated Myelopathy/Tropical Spastic Paraparesis: The First Case Report in Southeast Asia. ( 28343405 )
2017
26
Correction: Familial Clusters of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. ( 27028551 )
2016
27
Two Cases of Human T-Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis Caused by Living-Donor Renal Transplantation. ( 27777805 )
2016
28
HLA-G 3' untranslated region polymorphisms are associated with HTLV-1 infection, proviral load and HTLV-associated myelopathy/tropical spastic paraparesis development. ( 27449667 )
2016
29
Retrospective clinic and urodynamic study in the neurogenic bladder dysfunction caused by human T cell lymphotrophic virus type 1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). ( 26756420 )
2016
30
Clonus Associated with Tropical Spastic Paraparesis. ( 27783915 )
2016
31
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): A comparative study to identify factors that influence disease progression. ( 27871430 )
2016
32
Electrophysiological Analysis Shows Dizziness as the First Symptom in Human T Cell Lymphotropic Virus Type-Associated Myelopathy/Tropical Spastic Paraparesis. ( 25760424 )
2015
33
Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) and HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. ( 25820278 )
2015
34
Hypometabolism of watershed areas of the brain in HTLV-1-associated myelopathy/tropical spastic paraparesis. ( 26156876 )
2015
35
High IFN-I^/IL-10 Expression Ratio and Increased Frequency of Persistent Human T-Cell Lymphotropic Virus Type 1-Infected Clones Are Associated with Human T-Cell Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis Development. ( 25833232 )
2015
36
Neurological manifestations in individuals with HTLV-1-associated myelopathy/tropical spastic paraparesis in the Amazon. ( 26169165 )
2015
37
Common I^-chain blocking peptide reduces in vitro immune activation markers in HTLV-1-associated myelopathy/tropical spastic paraparesis. ( 26283355 )
2015
38
Neurological Manifestations in Human T-Cell Lymphotropic Virus Type 1 (HTLV-1)-Infected Individuals Without HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Longitudinal Cohort Study. ( 25820277 )
2015
39
Human T-lymphotropic virus 1 (HTLV-1)-associated lichenoid dermatitis induced by CD8(+) T cells in HTLV-1 carrier, HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T-cell leukemia/lymphoma. ( 26077665 )
2015
40
Postrenal Transplant Human T-Cell Lymphotropic Virus Type I-Associated Myelopathy/Tropical Spastic Paraparesis: A Case Report and Review of the Literature. ( 27500208 )
2015
41
HTLV-1-associated myelopathy/tropical spastic paraparesis. ( 27188208 )
2015
42
Deep Sequencing Analysis of Human T Cell Lymphotropic Virus Type 1 Long Terminal Repeat 5' Region from Patients with Tropical Spastic Paraparesis/Human T Cell Lymphotropic Virus Type 1-Associated Myelopathy and Asymptomatic Carriers. ( 26472535 )
2015
43
Tax secretion from peripheral blood mononuclear cells and tax detection in plasma of patients with human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis and asymptomatic carriers. ( 26241614 )
2015
44
Triple Therapy with Prednisolone, Pegylated Interferon and Sodium Valproate Improves Clinical Outcome and Reduces Human T-Cell Leukemia Virus Type 1 (HTLV-1) Proviral Load, Tax and HBZ mRNA Expression in Patients with HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis. ( 26174324 )
2015
45
HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Is Not Associated with SNP rs12979860 of the IL-28B Gene. ( 26609200 )
2015
46
Clinical presentation of axial myopathy in two siblings with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). ( 25884435 )
2015
47
Visualization of HTLV-1-specific cytotoxic T lymphocytes in the spinal cords of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis. ( 25470342 )
2015
48
A Peruvian family with a high burden of HTLV-1-associated myelopathy/tropical spastic paraparesis. ( 26392440 )
2015
49
Immunopathogenesis of HTLV-1-assoaciated myelopathy/tropical spastic paraparesis (HAM/TSP). ( 24704970 )
2014
50
Interferon beta-1a treatment in HTLV-1-associated myelopathy/tropical spastic paraparesis: a case report. ( 25229227 )
2014
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Variations for Myelopathy, Htlv-1-Associated

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Expression for Myelopathy, Htlv-1-Associated

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Search GEO for disease gene expression data for Myelopathy, Htlv-1-Associated.
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Pathways for Myelopathy, Htlv-1-Associated

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Pathways related to Myelopathy, Htlv-1-Associated according to KEGG:

37
# Name Kegg Source Accession
1 Human T-cell leukemia virus 1 infection hsa05166
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GO Terms for Myelopathy, Htlv-1-Associated

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Cellular components related to Myelopathy, Htlv-1-Associated according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 8.62 CNTN2 FASLG
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Sources for Myelopathy, Htlv-1-Associated

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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