MCID: MYB001
MIFTS: 28

Myoblastoma

Categories: Cancer diseases, Muscle diseases

Aliases & Classifications for Myoblastoma

MalaCards integrated aliases for Myoblastoma:

Name: Myoblastoma 12 15 70
Benign Granular Cell Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5039
MeSH 44 D009379
NCIt 50 C3252
UMLS 70 C0027043

Summaries for Myoblastoma

MalaCards based summary : Myoblastoma, also known as benign granular cell tumor, is related to malignant granular cell myoblastoma and congenital epulis. An important gene associated with Myoblastoma is ENO2 (Enolase 2), and among its related pathways/superpathways is Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include tongue, breast and lung.

Related Diseases for Myoblastoma

Diseases related to Myoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 273)
# Related Disease Score Top Affiliating Genes
1 malignant granular cell myoblastoma 32.3 ENO2 CD68
2 congenital epulis 32.1 ENO2 CD68
3 epulis 30.8 ENO2 CD68
4 granular cell tumor 30.8 SYP ENO2 CD68 CALB2
5 connective tissue benign neoplasm 30.3 ENO2 CD68 CALB2
6 gangliocytoma 30.0 SYP ENO2
7 glomus tumor 29.8 SYP ENO2 CALB2
8 alveolar soft part sarcoma 29.4 SYP MYOG ENO2 ASPSCR1
9 mediastinal granular cell myoblastoma 11.0
10 large cell carcinoma with rhabdoid phenotype 10.3 ENO2 CALB2
11 retroperitoneal hemangiopericytoma 10.3 ENO2 CD68
12 breast leiomyosarcoma 10.3 ENO2 CD68
13 pacinian tumor 10.3 ENO2 CALB2
14 spindle cell thymoma 10.3 ENO2 CALB2
15 congenital granular cell tumor 10.3 ENO2 CD68
16 pulmonary artery leiomyosarcoma 10.3 ENO2 CD68
17 skin granular cell tumor 10.3 ENO2 CD68
18 epididymal neoplasm 10.3 CD68 CALB2
19 vaginal glandular tumor 10.3 ENO2 CEACAM5
20 conventional fibrosarcoma 10.3 ENO2 CD68
21 liver leiomyosarcoma 10.3 ENO2 CALB2
22 neurilemmoma 10.3
23 fox-fordyce disease 10.3 CEACAM5 CD68
24 vulvar apocrine adenocarcinoma 10.3 ENO2 CEACAM5
25 paratesticular lipoma 10.3 ENO2 CEACAM5
26 lipoma of spermatic cord 10.3 ENO2 CEACAM5
27 malignant epithelial mesothelioma 10.3 CEACAM5 CALB2
28 dermoid cyst of ovary 10.3 CEACAM5 CALB2
29 heart lymphoma 10.3 MYOG CD68
30 myoma 10.3
31 liver sarcoma 10.3 CEACAM5 CD68
32 xanthogranulomatous cholecystitis 10.3 CEACAM5 CD68
33 central nervous system mesenchymal non-meningothelial tumor 10.3 MYOG ENO2
34 pericardial tuberculosis 10.3 CEACAM5 CALB2
35 malignant glandular tumor of peripheral nerve sheath 10.3 MYOG CALB2
36 pericardium cancer 10.3 CEACAM5 CALB2
37 esophageal tuberculosis 10.3 CEACAM5 CD68
38 pancreatic mucinous cystadenoma 10.3 CEACAM5 CALB2
39 ectomesenchymoma 10.3 MYOG ENO2
40 bone benign neoplasm 10.3 ENO2 CD68
41 urethral benign neoplasm 10.3 CEACAM5 CALB2
42 uterus leiomyosarcoma 10.3 MYOG ENO2
43 sclerosing hemangioma 10.2 SYP ENO2
44 malignant melanocytic neoplasm of the peripheral nerve sheath 10.2 SYP ENO2
45 malignant spiradenoma 10.2 CEACAM5 CALB2
46 breast rhabdomyosarcoma 10.2 MYOG ENO2
47 anal neuroendocrine tumor 10.2 SYP ENO2
48 optic nerve astrocytoma 10.2 SYP ENO2
49 cerebral neuroblastoma 10.2 SYP ENO2
50 neuronal intestinal dysplasia, type b 10.2 SYP ENO2

Graphical network of the top 20 diseases related to Myoblastoma:



Diseases related to Myoblastoma

Symptoms & Phenotypes for Myoblastoma

Drugs & Therapeutics for Myoblastoma

Search Clinical Trials , NIH Clinical Center for Myoblastoma

Genetic Tests for Myoblastoma

Anatomical Context for Myoblastoma

MalaCards organs/tissues related to Myoblastoma:

40
Tongue, Breast, Lung, Pineal, Trachea, Colon, Heart

Publications for Myoblastoma

Articles related to Myoblastoma:

(show top 50) (show all 767)
# Title Authors PMID Year
1
Laryngeal granular cell tumors in children: A literature review. 61
32705988 2020
2
A Case of Synchronous Malignant and Benign Granular Cell Tumor of the Vulva. 61
32947331 2020
3
Glass-coated ferromagnetic microwire-induced magnetic hyperthermia for in vitro cancer cell treatment. 61
31753330 2020
4
Pediatric Granular Cell Tumor of the Breast: An uncommon neoplasm in an uncommon site and age group. 61
31372359 2019
5
Benign Granular Cell Tumor of the Cecum. 61
31019852 2019
6
Granular Cell Tumor over the Mons Pubis: An Uncommon Tumor. 61
31223510 2019
7
Granular cell tumor of the breast mimicking malignancy: a case report with a literature review. 61
30559976 2018
8
Granular cell tumor in breast: a case report. 61
28442932 2017
9
Intramuscular Hibernoma of the Scapular Region Misdiagnosed on Cytology as a Malignant Lesion: A Report of a Rare Case. 61
29563939 2017
10
Benign Granular Cell Tumor of Breast. 61
27124422 2016
11
In Vitro Selective Anti-Proliferative Effect of Zinc Oxide Nanoparticles Against Co-Cultured C2C12 Myoblastoma Cancer and 3T3-L1 Normal Cells. 61
26563419 2016
12
Granular cell tumor presenting in the scrotum of a pediatric patient: a case report and review of the literature. 61
27259474 2016
13
Abrikossoff's tumor mimicking endometrial tumor--literature review and case report of the first described granular cell tumor in scar tissue after caesarean section. 61
27172759 2016
14
Myoblastoma of the breast: Our experience and review of literature. 61
26971123 2016
15
Anabolic effect of the traditional Chinese medicine compound tanshinone IIA on myotube hypertrophy is mediated by estrogen receptor. 61
26018796 2015
16
Granular cell tumor of the esophagus with elevated preoperative serum carbohydrate antigen 19-9: a case report. 61
25692443 2015
17
Benign granular-cell tumor of the breast: Case report and literature review. 61
27398126 2015
18
Granular cell tumor in the breast mimicking breast carcinoma. 61
25597209 2014
19
Estrogen receptor beta is involved in skeletal muscle hypertrophy induced by the phytoecdysteroid ecdysterone. 61
24974955 2014
20
Extra-nuclear telomerase reverse transcriptase (TERT) regulates glucose transport in skeletal muscle cells. 61
24970747 2014
21
Benign granular cell tumor of the lung in a child--a case report. 61
24617707 2014
22
Is fine needle aspiration cytology a useful diagnostic tool for granular cell tumors? A cytohistological review with emphasis on pitfalls. 61
25379050 2014
23
Abrikossoff's Tumor: An Unusual Presentation. 61
24082205 2013
24
Granular cell tumor of the abdominal wall: case report and review of the literature. 61
24294803 2013
25
Granular cell tumor on perianal region: a case report. 61
23945899 2013
26
Granular cell tumor in a male breast: mammographic, sonographic, and pathologic features. 61
22730008 2013
27
Uterine cervical malignant granular cell tumor. 61
22414028 2012
28
Benign granular cell tumor of the vulva: first report of multiple cases in a family. 61
22517025 2012
29
Malignant clinical presentation of a benign granular cell tumor of breast in a patient with previously treated contralateral invasive ductal carcinoma. 61
23243536 2012
30
Granular cell tumor of the male breast. 61
21318418 2011
31
Granular cell tumour of the tongue in a 14-year-old boy: case report. 61
22058595 2011
32
Endoscopic resection of intrathoracic tumors: experience with and long-term results for 26 patients. 61
21250809 2011
33
The molecular basis for venation patterning of pigmentation and its effect on pollinator attraction in flowers of Antirrhinum. 61
21039563 2011
34
Granular cell tumor of the lung. 61
20066540 2010
35
alpha-Lipoic acid increases energy expenditure by enhancing adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling in the skeletal muscle of aged mice. 61
20015518 2010
36
Granular cell myoblastoma of the tongue in a 2-year-old girl: a case report. 61
21043356 2010
37
Granular cell myoblastoma of tongue: a rare cause of unanticipated difficult intubation. 61
20394257 2010
38
Vascular invasion demonstrated by elastic stain-a common phenomenon in benign granular cell tumors. 61
19066954 2009
39
Laryngeal granular cell tumor. 61
17134875 2008
40
C2C12 myoblastoma cell differentiation and proliferation is stimulated by androgens and associated with a modulation of myostatin and Pax7 expression. 61
18434429 2008
41
Intramedullary astrocytoma with granular cell differentiation. 61
17483971 2007
42
Recurrent granular cell tumor: how to treat. 61
17912112 2007
43
A case of granular cell tumor of the trachea. 61
17616025 2007
44
[Statistical study of the evolution over ten years of the clinical and therapeutic approach in childhood soft tissue sarcoma]. 61
17983168 2007
45
Cytodiagnosis of granular cell tumor: a case report. 61
17474262 2007
46
[Prenatal diagnosis of granular cell myoblastoma--a case report]. 61
17633900 2006
47
[Granular cell tumor -- a rare tumor lesion of submandibular gland origin]. 61
16231244 2005
48
Multiple plaques on the back: S-100 negative benign granular cell tumor. 61
16335876 2005
49
A rare female genital tract tumor: benign granular cell tumor of vulva: case report and review of the literature. 61
15863174 2005
50
Pediatric subglottic granular cell myoblastoma. 61
15806064 2005

Variations for Myoblastoma

Expression for Myoblastoma

Search GEO for disease gene expression data for Myoblastoma.

Pathways for Myoblastoma

Pathways related to Myoblastoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.86 CEACAM6 CEACAM5 CD68

GO Terms for Myoblastoma

Cellular components related to Myoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 synaptic membrane GO:0097060 8.62 CDH8 CALB2

Biological processes related to Myoblastoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 9.13 CEACAM6 CEACAM5 CDH8
2 negative regulation of anoikis GO:2000811 8.62 CEACAM6 CEACAM5

Sources for Myoblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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