MCI2
MCID: MYC058
MIFTS: 26

Myocardial Infarction 2 (MCI2)

Categories: Blood diseases, Cardiovascular diseases, Genetic diseases, Oral diseases, Respiratory diseases

Aliases & Classifications for Myocardial Infarction 2

MalaCards integrated aliases for Myocardial Infarction 2:

Name: Myocardial Infarction 2 57
Myocardial Infarction, Susceptibility to, 2 57 13 73
Mci2 57

Classifications:



External Ids:

OMIM 57 608557
UMLS 73 C1837871

Summaries for Myocardial Infarction 2

MalaCards based summary : Myocardial Infarction 2, also known as myocardial infarction, susceptibility to, 2, is related to myocardial infarction and acute myocardial infarction. An important gene associated with Myocardial Infarction 2 is MCI2 (Myocardial Infarction, Susceptiblity To, 2). The drugs Simvastatin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and neutrophil.

Description from OMIM: 608557

Related Diseases for Myocardial Infarction 2

Diseases in the Myocardial Infarction family:

Myocardial Infarction 2 Acute Myocardial Infarction
Posterior Myocardial Infarction

Diseases related to Myocardial Infarction 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 myocardial infarction 30.3 MCI2 PLAT
2 acute myocardial infarction 10.5
3 progressive familial heart block, type ia 10.0
4 diabetes mellitus 9.9
5 left bundle branch hemiblock 9.8
6 inferior myocardial infarction 9.8
7 cardiogenic shock 9.8

Graphical network of the top 20 diseases related to Myocardial Infarction 2:



Diseases related to Myocardial Infarction 2

Symptoms & Phenotypes for Myocardial Infarction 2

Clinical features from OMIM:

608557

Drugs & Therapeutics for Myocardial Infarction 2

Drugs for Myocardial Infarction 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 39)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Simvastatin Approved Phase 4 79902-63-9 54454
2
Clopidogrel Approved Phase 4 113665-84-2, 120202-66-6 60606
3
Paclitaxel Approved, Vet_approved Phase 4 33069-62-4 36314
4
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
5
Ticlopidine Approved Phase 4 55142-85-3 5472
6
Everolimus Approved Phase 4 159351-69-6 6442177
7
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
8
Sirolimus Approved, Investigational Phase 4 53123-88-9 46835353 6436030 5284616
9 Lipid Regulating Agents Phase 4
10 Calcium, Dietary Phase 4
11 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
12 Atorvastatin Calcium Phase 4 134523-03-8
13 Hypolipidemic Agents Phase 4
14 Antimetabolites Phase 4
15 Anticholesteremic Agents Phase 4
16 Neurotransmitter Agents Phase 4
17 Purinergic P2 Receptor Antagonists Phase 4
18 Antibiotics, Antitubercular Phase 4
19 Anti-Inflammatory Agents Phase 4
20 Immunologic Factors Phase 4
21 Cytochrome P-450 CYP2C19 Inhibitors Phase 4
22 Platelet Aggregation Inhibitors Phase 4
23 Antineoplastic Agents, Phytogenic Phase 4
24 Anti-Inflammatory Agents, Non-Steroidal Phase 4
25 Antifungal Agents Phase 4
26 Purinergic P2Y Receptor Antagonists Phase 4
27 Analgesics Phase 4
28 Cytochrome P-450 Enzyme Inhibitors Phase 4
29 Peripheral Nervous System Agents Phase 4
30 Antimitotic Agents Phase 4
31 Anti-Bacterial Agents Phase 4
32 Albumin-Bound Paclitaxel Phase 4
33 Immunosuppressive Agents Phase 4
34 Anti-Infective Agents Phase 4
35 Analgesics, Non-Narcotic Phase 4
36 Fibrinolytic Agents Phase 4
37 Cyclooxygenase Inhibitors Phase 4
38 Antipyretics Phase 4
39 Antirheumatic Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHD Completed NCT00159835 Phase 4 atorvastatin;simvastatin
2 Synergy Between Stent and Drugs to Avoid Ischemic Recurrences After Percutaneous Coronary Intervention Completed NCT00611286 Phase 4 clopidogrel treatment after bare metal stent implantation;clopidogrel treatment after bare metal stent implantation;clopidogrel after zotarolimus-eluting stent implantation;clopidogrel after paclitaxel-eluting stent implantation;clopidogrel after everolimus-eluting stent implantation;clopidogrel after zotarolimus-eluting stent implantation;clopidogrel after paclitaxel-eluting stent implantation;clopidogrel after everolimus-eluting stent implantation

Search NIH Clinical Center for Myocardial Infarction 2

Genetic Tests for Myocardial Infarction 2

Anatomical Context for Myocardial Infarction 2

MalaCards organs/tissues related to Myocardial Infarction 2:

41
Heart, Testes, Neutrophil, Atrioventricular Node

Publications for Myocardial Infarction 2

Articles related to Myocardial Infarction 2:

(show all 50)
# Title Authors Year
1
Copeptin and insulin-like growth factor binding protein-1 during follow-up after an acute myocardial infarction in patients with type 2 diabetes: A report from the Diabetes Mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction 2 cohort. ( 30309264 )
2018
2
Early-Phase Vascular Healing of Bioabsorbable vs. Durable Polymer-Coated Everolimus-Eluting Stents in Patients With ST-Elevation Myocardial Infarction - 2-Week and 4-Month Analyses With Optical Coherence Tomography. ( 29998921 )
2018
3
Direct Comparison of 2 Rule-Out Strategies for Acute Myocardial Infarction: 2-h Accelerated Diagnostic Protocol vs 2-h Algorithm. ( 28515106 )
2017
4
Development of an experimentally useful model of acute myocardial infarction: 2/3 nephrectomized triple nitric oxide synthases-deficient mouse. ( 25265498 )
2014
5
The EXAMINATION Trial (Everolimus-Eluting Stents Versus Bare-Metal Stents in ST-Segment Elevation Myocardial Infarction): 2-Year Results From a Multicenter Randomized Controlled Trial. ( 24332423 )
2014
6
Comparison of drug-eluting stents with bare metal stents implantation for the treatment of acute ST-elevation myocardial infarction: 2-year clinical outcomes from single-center registry. ( 21518587 )
2011
7
System delay and timing of intervention in acute myocardial infarction (from the Danish Acute Myocardial Infarction-2 [DANAMI-2] trial). ( 21757183 )
2011
8
Time to treatment and three-year mortality after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction-a DANish Trial in Acute Myocardial Infarction-2 (DANAMI-2) substudy. ( 20494656 )
2010
9
Letter by Fresco regarding article "Primary angioplasty versus fibrinolysis in acute myocardial infarction: long-term follow-up in the Danish Acute Myocardial Infarction 2 trial". ( 21173360 )
2010
10
Primary angioplasty versus fibrinolysis in acute myocardial infarction: long-term follow-up in the Danish acute myocardial infarction 2 trial. ( 20308618 )
2010
11
Long-term prognostic value of ST-segment resolution in patients treated with fibrinolysis or primary percutaneous coronary intervention results from the DANAMI-2 (DANish trial in acute myocardial infarction-2). ( 19874989 )
2009
12
Timing of ischemic onset estimated from the electrocardiogram is better than historical timing for predicting outcome after reperfusion therapy for acute anterior myocardial infarction: a DANish trial in Acute Myocardial Infarction 2 (DANAMI-2) substudy. ( 17584552 )
2007
13
Prognostic evaluation by clinical exercise test scores in patients treated with primary percutaneous coronary intervention or fibrinolysis for acute myocardial infarction (a Danish Trial in Acute Myocardial Infarction-2 Sub-Study). ( 17884364 )
2007
14
Prevalence and prognostic implications of ST-segment deviations from ambulatory Holter monitoring after ST-segment elevation myocardial infarction treated with either fibrinolysis or primary percutaneous coronary intervention (a Danish Trial in Acute Myocardial Infarction-2 Substudy). ( 17826373 )
2007
15
Neutrophil-mediated accumulation of 2-ClHDA during myocardial infarction: 2-ClHDA-mediated myocardial injury. ( 15681699 )
2005
16
Outcome in patients transferred for percutaneous coronary intervention (a national registry of myocardial infarction 2/3/4 analysis). ( 16253587 )
2005
17
Danish multicenter randomized study on fibrinolytic therapy versus acute coronary angioplasty in acute myocardial infarction: rationale and design of the DANish trial in Acute Myocardial Infarction-2 (DANAMI-2). ( 12891190 )
2003
18
A risk model derived from the National Registry of Myocardial Infarction 2 database for predicting mortality after coronary artery bypass grafting during acute myocardial infarction. ( 12088769 )
2002
19
Use of emergency medical services in acute myocardial infarction and subsequent quality of care: observations from the National Registry of Myocardial Infarction 2. ( 12473545 )
2002
20
Prognostic value of colour Doppler echocardiography in patients after myocardial infarction--2-year follow-up. ( 11918159 )
2002
21
Smoking and mortality following acute myocardial infarction: results from the National Registry of Myocardial Infarction 2 (NRMI 2). ( 11906686 )
2002
22
Death or nonfatal stroke in patients with acute myocardial infarction treated with tissue plasminogen activator. Participants in the National Registry of Myocardial Infarction 2. ( 11230850 )
2001
23
The use of intra-aortic balloon counterpulsation in patients with cardiogenic shock complicating acute myocardial infarction: data from the National Registry of Myocardial Infarction 2. ( 11376306 )
2001
24
The volume of primary angioplasty procedures and survival after acute myocardial infarction. National Registry of Myocardial Infarction 2 Investigators. ( 10824077 )
2000
25
Intracranial hemorrhage rates and effect of immediate beta-blocker use in patients with acute myocardial infarction treated with tissue plasminogen activator. Participants in the National Registry of Myocardial Infarction-2. ( 11078295 )
2000
26
Treatment and outcomes of left bundle-branch block patients with myocardial infarction who present without chest pain. National Registry of Myocardial Infarction 2 Investigators. ( 10987588 )
2000
27
Impact of history of diabetes mellitus on hospital mortality in men and women with first acute myocardial infarction. The National Registry of Myocardial Infarction 2 Participants. ( 10856398 )
2000
28
Payer status and the utilization of hospital resources in acute myocardial infarction: a report from the National Registry of Myocardial Infarction 2. ( 10737281 )
2000
29
Sex-based differences in early mortality after myocardial infarction. National Registry of Myocardial Infarction 2 Participants. ( 10413733 )
1999
30
Reperfusion therapy for acute myocardial infarction: observations from the National Registry of Myocardial Infarction 2. ( 10423667 )
1999
31
The association between the on-site availability of cardiac procedures and the utilization of those services for acute myocardial infarction by payer group. The National Registry of Myocardial Infarction 2 Investigators. ( 10492841 )
1999
32
Early use of ACE inhibitors in the treatment of acute myocardial infarction in the United States: experience from the National Registry of Myocardial Infarction 2. National Registry of Myocardial Infarction 2 participants. ( 10569326 )
1999
33
A comparison of the national registry of myocardial infarction 2 with the cooperative cardiovascular project. ( 10362189 )
1999
34
Reperfusion therapy in patients with acute myocardial infarction and prior coronary artery bypass graft surgery (National Registry of Myocardial Infarction-2). ( 10614792 )
1999
35
Risk for intracranial hemorrhage after tissue plasminogen activator treatment for acute myocardial infarction. Participants in the National Registry of Myocardial Infarction 2. ( 9786806 )
1998
36
Bundle-branch block and in-hospital mortality in acute myocardial infarction. National Registry of Myocardial Infarction 2 Investigators. ( 9841600 )
1998
37
Use of reperfusion therapy for acute myocardial infarction in the United States: data from the National Registry of Myocardial Infarction 2. ( 9537341 )
1998
38
Presenting characteristics, treatment patterns, and clinical outcomes of non-black minorities in the National Registry of Myocardial Infarction 2. ( 9817473 )
1998
39
Use of angiotensin-converting enzyme inhibitors at discharge in patients with acute myocardial infarction in the United States: data from the National Registry of Myocardial Infarction 2. ( 9708461 )
1998
40
Management and outcomes for black patients with acute myocardial infarction in the reperfusion era. National Registry of Myocardial Infarction 2 Investigators. ( 9817474 )
1998
41
The prehospital electrocardiogram in acute myocardial infarction: is its full potential being realized? National Registry of Myocardial Infarction 2 Investigators. ( 9060884 )
1997
42
Critical appraisal of secondary prevention after myocardial infarction. 2-3 September 1983, LiA"ge, Belgium. ( 3758096 )
1986
43
Recurrent myocardial infarction. 2. Possibilities of prediction. ( 4029186 )
1985
44
Thrombolytic therapy. A new strategy for the treatment of acute myocardial infarction (2). ( 6236369 )
1984
45
Dissociation of the atrioventricular node in acute inferior wall myocardial infarction. 2. Longitudinal dissociation (dual atrioventricular nodal pathways). ( 648218 )
1978
46
The clinical significance of bundle branch block complicating acute myocardial infarction. 2. Indications for temporary and permanent pacemaker insertion. ( 688580 )
1978
47
Myocardial infarction. 2. ( 4844740 )
1974
48
Management of dysrhythmias associated with acute myocardial infarction. 2. ( 5130352 )
1971
49
Treatment of acute myocardial infarction. 2. Ventricular ectopic arrhythmias. ( 4194547 )
1970
50
Diseases of the heart and blood-vessels. Recovery after myocardial infarction--2. ( 5941505 )
1966

Variations for Myocardial Infarction 2

Expression for Myocardial Infarction 2

Search GEO for disease gene expression data for Myocardial Infarction 2.

Pathways for Myocardial Infarction 2

GO Terms for Myocardial Infarction 2

Sources for Myocardial Infarction 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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