MCID: MYC058
MIFTS: 25

Myocardial Infarction 2

Categories: Genetic diseases, Cardiovascular diseases

Aliases & Classifications for Myocardial Infarction 2

MalaCards integrated aliases for Myocardial Infarction 2:

Name: Myocardial Infarction 2 57
Myocardial Infarction, Susceptibility to, 2 57 13 73
Mci2 57

Classifications:



External Ids:

OMIM 57 608557
UMLS 73 C1837871

Summaries for Myocardial Infarction 2

MalaCards based summary : Myocardial Infarction 2, also known as myocardial infarction, susceptibility to, 2, is related to myocardial infarction and acute myocardial infarction. An important gene associated with Myocardial Infarction 2 is MCI2 (Myocardial Infarction, Susceptiblity To, 2). The drugs Simvastatin and Aspirin have been mentioned in the context of this disorder. Affiliated tissues include heart and atrioventricular node.

Description from OMIM: 608557

Related Diseases for Myocardial Infarction 2

Diseases in the Myocardial Infarction family:

Myocardial Infarction 2 Acute Myocardial Infarction
Posterior Myocardial Infarction

Diseases related to Myocardial Infarction 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 myocardial infarction 29.1 MCI2 PLAT
2 acute myocardial infarction 10.4
3 progressive familial heart block, type ia 9.9
4 diabetes mellitus 9.7
5 left bundle branch hemiblock 9.7
6 inferior myocardial infarction 9.7
7 cardiogenic shock 9.7

Graphical network of the top 20 diseases related to Myocardial Infarction 2:



Diseases related to Myocardial Infarction 2

Symptoms & Phenotypes for Myocardial Infarction 2

Clinical features from OMIM:

608557

Drugs & Therapeutics for Myocardial Infarction 2

Drugs for Myocardial Infarction 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 37)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Simvastatin Approved Phase 4 79902-63-9 54454
2
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
3
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
4
Everolimus Approved Phase 4 159351-69-6 6442177
5
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
6
Paclitaxel Approved, Vet_approved Phase 4 33069-62-4 36314
7
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
8
Ticlopidine Approved Phase 4 55142-85-3 5472
9 Anticholesteremic Agents Phase 4
10 Antimetabolites Phase 4
11 Atorvastatin Calcium Phase 4 134523-03-8
12 Calcium, Dietary Phase 4
13 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
14 Hypolipidemic Agents Phase 4
15 Lipid Regulating Agents Phase 4
16 Albumin-Bound Paclitaxel Phase 4
17 Analgesics Phase 4
18 Analgesics, Non-Narcotic Phase 4
19 Anti-Bacterial Agents Phase 4
20 Antibiotics, Antitubercular Phase 4
21 Antifungal Agents Phase 4
22 Anti-Infective Agents Phase 4
23 Anti-Inflammatory Agents Phase 4
24 Anti-Inflammatory Agents, Non-Steroidal Phase 4
25 Antimitotic Agents Phase 4
26 Antineoplastic Agents, Phytogenic Phase 4
27 Antipyretics Phase 4
28 Antirheumatic Agents Phase 4
29 Cyclooxygenase Inhibitors Phase 4
30 Cytochrome P-450 Enzyme Inhibitors Phase 4
31 Fibrinolytic Agents Phase 4
32 Immunosuppressive Agents Phase 4
33 Neurotransmitter Agents Phase 4
34 Peripheral Nervous System Agents Phase 4
35 Platelet Aggregation Inhibitors Phase 4
36 Purinergic P2 Receptor Antagonists Phase 4
37 Purinergic P2Y Receptor Antagonists Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHD Completed NCT00159835 Phase 4 atorvastatin;simvastatin
2 Synergy Between Stent and Drugs to Avoid Ischemic Recurrences After Percutaneous Coronary Intervention Completed NCT00611286 Phase 4 clopidogrel treatment after bare metal stent implantation;clopidogrel treatment after bare metal stent implantation;clopidogrel after zotarolimus-eluting stent implantation;clopidogrel after paclitaxel-eluting stent implantation;clopidogrel after everolimus-eluting stent implantation;clopidogrel after zotarolimus-eluting stent implantation;clopidogrel after paclitaxel-eluting stent implantation;clopidogrel after everolimus-eluting stent implantation

Search NIH Clinical Center for Myocardial Infarction 2

Genetic Tests for Myocardial Infarction 2

Anatomical Context for Myocardial Infarction 2

MalaCards organs/tissues related to Myocardial Infarction 2:

41
Heart, Atrioventricular Node

Publications for Myocardial Infarction 2

Articles related to Myocardial Infarction 2:

(show all 32)
# Title Authors Year
1
Letter by Fresco regarding article "Primary angioplasty versus fibrinolysis in acute myocardial infarction: long-term follow-up in the Danish Acute Myocardial Infarction 2 trial". ( 21173360 )
2010
2
Primary angioplasty versus fibrinolysis in acute myocardial infarction: long-term follow-up in the Danish acute myocardial infarction 2 trial. ( 20308618 )
2010
3
Timing of ischemic onset estimated from the electrocardiogram is better than historical timing for predicting outcome after reperfusion therapy for acute anterior myocardial infarction: a DANish trial in Acute Myocardial Infarction 2 (DANAMI-2) substudy. ( 17584552 )
2007
4
A risk model derived from the National Registry of Myocardial Infarction 2 database for predicting mortality after coronary artery bypass grafting during acute myocardial infarction. ( 12088769 )
2002
5
Use of emergency medical services in acute myocardial infarction and subsequent quality of care: observations from the National Registry of Myocardial Infarction 2. ( 12473545 )
2002
6
Smoking and mortality following acute myocardial infarction: results from the National Registry of Myocardial Infarction 2 (NRMI 2). ( 11906686 )
2002
7
Death or nonfatal stroke in patients with acute myocardial infarction treated with tissue plasminogen activator. Participants in the National Registry of Myocardial Infarction 2. ( 11230850 )
2001
8
The use of intra-aortic balloon counterpulsation in patients with cardiogenic shock complicating acute myocardial infarction: data from the National Registry of Myocardial Infarction 2. ( 11376306 )
2001
9
The volume of primary angioplasty procedures and survival after acute myocardial infarction. National Registry of Myocardial Infarction 2 Investigators. ( 10824077 )
2000
10
Treatment and outcomes of left bundle-branch block patients with myocardial infarction who present without chest pain. National Registry of Myocardial Infarction 2 Investigators. ( 10987588 )
2000
11
Impact of history of diabetes mellitus on hospital mortality in men and women with first acute myocardial infarction. The National Registry of Myocardial Infarction 2 Participants. ( 10856398 )
2000
12
Payer status and the utilization of hospital resources in acute myocardial infarction: a report from the National Registry of Myocardial Infarction 2. ( 10737281 )
2000
13
Sex-based differences in early mortality after myocardial infarction. National Registry of Myocardial Infarction 2 Participants. ( 10413733 )
1999
14
Reperfusion therapy for acute myocardial infarction: observations from the National Registry of Myocardial Infarction 2. ( 10423667 )
1999
15
The association between the on-site availability of cardiac procedures and the utilization of those services for acute myocardial infarction by payer group. The National Registry of Myocardial Infarction 2 Investigators. ( 10492841 )
1999
16
Early use of ACE inhibitors in the treatment of acute myocardial infarction in the United States: experience from the National Registry of Myocardial Infarction 2. National Registry of Myocardial Infarction 2 participants. ( 10569326 )
1999
17
A comparison of the national registry of myocardial infarction 2 with the cooperative cardiovascular project. ( 10362189 )
1999
18
Risk for intracranial hemorrhage after tissue plasminogen activator treatment for acute myocardial infarction. Participants in the National Registry of Myocardial Infarction 2. ( 9786806 )
1998
19
Bundle-branch block and in-hospital mortality in acute myocardial infarction. National Registry of Myocardial Infarction 2 Investigators. ( 9841600 )
1998
20
Use of reperfusion therapy for acute myocardial infarction in the United States: data from the National Registry of Myocardial Infarction 2. ( 9537341 )
1998
21
Presenting characteristics, treatment patterns, and clinical outcomes of non-black minorities in the National Registry of Myocardial Infarction 2. ( 9817473 )
1998
22
Use of angiotensin-converting enzyme inhibitors at discharge in patients with acute myocardial infarction in the United States: data from the National Registry of Myocardial Infarction 2. ( 9708461 )
1998
23
Management and outcomes for black patients with acute myocardial infarction in the reperfusion era. National Registry of Myocardial Infarction 2 Investigators. ( 9817474 )
1998
24
The prehospital electrocardiogram in acute myocardial infarction: is its full potential being realized? National Registry of Myocardial Infarction 2 Investigators. ( 9060884 )
1997
25
Recurrent myocardial infarction. 2. Possibilities of prediction. ( 4029186 )
1985
26
Thrombolytic therapy. A new strategy for the treatment of acute myocardial infarction (2). ( 6236369 )
1984
27
Dissociation of the atrioventricular node in acute inferior wall myocardial infarction. 2. Longitudinal dissociation (dual atrioventricular nodal pathways). ( 648218 )
1978
28
The clinical significance of bundle branch block complicating acute myocardial infarction. 2. Indications for temporary and permanent pacemaker insertion. ( 688580 )
1978
29
Myocardial infarction. 2. ( 4844740 )
1974
30
Management of dysrhythmias associated with acute myocardial infarction. 2. ( 5130352 )
1971
31
Treatment of acute myocardial infarction. 2. Ventricular ectopic arrhythmias. ( 4194547 )
1970
32
Diseases of the heart and blood-vessels. Recovery after myocardial infarction--2. ( 5941505 )
1966

Variations for Myocardial Infarction 2

Expression for Myocardial Infarction 2

Search GEO for disease gene expression data for Myocardial Infarction 2.

Pathways for Myocardial Infarction 2

GO Terms for Myocardial Infarction 2

Sources for Myocardial Infarction 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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