Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect
Release Notes Disease Lists/Categories
About
About MalaCards Datasets Our Publications Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: MYF002
MIFTS: 44

Myofascial Pain Syndrome

Categories: Muscle diseases
Data Licensing
For inquiries, contact:
[email protected]
Genes Tissues Related diseases Publications Symptoms & Phenotypes Drugs
Sources

Aliases & Classifications for Myofascial Pain Syndrome

About this section

MalaCards integrated aliases for Myofascial Pain Syndrome:

Name: Myofascial Pain Syndrome 11 14 16 75
Myofascial Pain Syndromes 43 71
Myofascial Pain Dysfunction Syndrome 53
Fibromyalgia 71

Classifications:

MalaCards categories:
Anatomical: Muscle diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 11 DOID:431
MeSH 43 D009209
UMLS 71 C0016053 C0027073
Sources

Summaries for Myofascial Pain Syndrome

About this section

MalaCards based summary: Myofascial Pain Syndrome, also known as myofascial pain syndromes, is related to fibromyalgia and chronic pain, and has symptoms including muscle weakness, fatigue and myoclonus. An important gene associated with Myofascial Pain Syndrome is LAPTM4A (Lysosomal Protein Transmembrane 4 Alpha), and among its related pathways/superpathways are CREB Pathway and Sudden infant death syndrome (SIDS) susceptibility pathways. The drugs Etoricoxib and Modafinil have been mentioned in the context of this disorder. Affiliated tissues include brain, skeletal muscle and spinal cord, and related phenotypes are homeostasis/metabolism and behavior/neurological

Wikipedia: 75 Myofascial pain syndrome (MPS), also known as chronic myofascial pain (CMP), is a syndrome characterized... more...
Sources

Related Diseases for Myofascial Pain Syndrome

About this section

Diseases related to Myofascial Pain Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 179)
# Related Disease Score Top Affiliating Genes
1 fibromyalgia 31.8 P2RX3 NGF CALCA BDNF
2 chronic pain 30.7 P2RX3 BDNF
3 radiculopathy 30.4 TAC1 LAPTM4A CALCA
4 facial neuralgia 30.3 LIPN LAPTM4A
5 paine syndrome 30.1 TRPV1 TAC1 P2RX3 NGF LAPTM4A KNG1
6 allergic disease 29.9 TAC1 KNG1 BDNF
7 irritable bowel syndrome 29.9 TRPV1 TAC1 NGF BDNF
8 glossopharyngeal neuralgia 29.9 TRPV1 TAC1 P2RX3 CALCA
9 anxiety 29.8 TRPV1 TAC1 NGF BDNF
10 bursitis 29.6 TAC1 PARPBP LAPTM4A KNG1 CALCA
11 reflex sympathetic dystrophy 29.4 TRPV1 TAC1 PARPBP NGF CALCA
12 trigeminal neuralgia 29.1 TRPV1 TAC1 P2RX3 NGF CALCA BDNF
13 complex regional pain syndrome 28.8 TRPV1 TAC1 P2RX3 NGF KNG1 CALCA
14 interstitial cystitis 28.6 TRPV1 TAC1 P2RX3 NGF KNG1 CALCA
15 peripheral nervous system disease 28.6 TRPV1 TAC1 P2RX3 NGF KNG1 CALCA
16 somatoform disorder 28.5 TRPV1 TAC1 P2RX3 NGF LAPTM4A KNG1
17 scheie syndrome 10.9
18 trichorhinophalangeal syndrome 10.5
19 chronic fatigue syndrome 10.5
20 bruxism 10.5
21 blood group, cromer system 10.4
22 carbamazepine allergy 10.3 TAC1 CALCA
23 patellofemoral pain syndrome 10.3 TAC1 LAPTM4A
24 taylor's syndrome 10.3 TAC1 CALCA
25 lateral medullary syndrome 10.3 TAC1 CALCA
26 glossopharyngeal nerve disease 10.3 TAC1 CALCA
27 hyperhidrosis, gustatory 10.2 TRPV1 TAC1
28 dermatographia 10.2 TAC1 KNG1
29 paralytic ileus 10.2 TAC1 CALCA
30 ocular hyperemia 10.2 TRPV1 TAC1
31 uvulitis 10.2 TRPV1 KNG1
32 spasticity 10.2
33 physical urticaria 10.2 TAC1 KNG1
34 photokeratitis 10.2 TRPV1 TAC1
35 akinetopsia 10.2 TAC1 KNG1
36 endobronchial lipoma 10.2 TAC1 KNG1
37 neurogenic arthropathy 10.2 NGF CALCA
38 pyogenic sterile arthritis, pyoderma gangrenosum, and acne 10.2
39 fasciitis 10.2
40 48,xyyy 10.2
41 heel spur 10.1 LIPN LAPTM4A
42 punctate epithelial keratoconjunctivitis 10.1 TAC1 NGF
43 perianal hematoma 10.1 TAC1 KNG1 CALCA
44 lagophthalmos 10.1 TAC1 NGF
45 interval angle-closure glaucoma 10.1 TAC1 KNG1 CALCA
46 patellar tendinitis 10.1 TAC1 PARPBP
47 recurrent corneal erosion 10.1 TAC1 NGF
48 mononeuritis of lower limb 10.1 TRPV1 NGF
49 brain stem infarction 10.1 TAC1 LIPN
50 horner's syndrome 10.1 NGF CALCA

Graphical network of the top 20 diseases related to Myofascial Pain Syndrome:



Diseases related to Myofascial Pain Syndrome
Sources

Symptoms & Phenotypes for Myofascial Pain Syndrome

About this section

UMLS symptoms related to Myofascial Pain Syndrome:


muscle weakness; fatigue; myoclonus; back pain; myalgia; torticollis; pain; chronic pain; sciatica; muscle cramp; muscle rigidity; muscle spasticity; myofascial trigger point pain

MGI Mouse Phenotypes related to Myofascial Pain Syndrome:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.85 ASIC3 BDNF CALCA KNG1 LAPTM4A LIPN
2 behavior/neurological MP:0005386 9.61 ASIC3 BDNF CALCA KNG1 NGF P2RX3
3 integument MP:0010771 9.23 ASIC3 BDNF CALCA NGF P2RX3 PDGFRB
Sources

Drugs & Therapeutics for Myofascial Pain Syndrome

About this section

Drugs for Myofascial Pain Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 318)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
2
Modafinil Approved, Investigational Phase 4 68693-11-8 4236
3
Tramadol Approved, Investigational Phase 4 27203-92-5 33741 5523
4
Trazodone Approved, Investigational Phase 4 19794-93-5 5533
5
Fluoxetine Approved, Vet_approved Phase 4 54910-89-3 3386
6
Eszopiclone Approved, Investigational Phase 4 138729-47-2 969472
7
Paroxetine Approved, Investigational Phase 4 61869-08-7 43815
8
Sodium citrate Approved, Investigational Phase 4 68-04-2 23431961
9
Histamine Approved, Investigational Phase 4 51-45-6 774
10
Granisetron Approved, Investigational Phase 4 109889-09-0 3510 5284566
11
Flunarizine Approved Phase 4 52468-60-7 941361
12
Amitriptyline Approved Phase 4 50-48-6 2160
13
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
14
Ibuprofen Approved Phase 4 15687-27-1 3672
15
Ethanol Approved Phase 4 64-17-5 702
16
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
17
Cyclobenzaprine Approved Phase 4 303-53-7 2895
18
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
19
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
20
Diphenhydramine Approved, Investigational Phase 4 147-24-0, 58-73-1 3100
21
Suvorexant Approved, Investigational Phase 4 1030377-33-3 57505028 24965990
22
Promethazine Approved, Investigational Phase 4 60-87-7 4927
23
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
24
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 22737-96-8, 68-26-8 5280382 445354
25 Cyclooxygenase 2 Inhibitors Phase 4
26 Antiviral Agents Phase 4
27 Opiate Alkaloids Phase 4
28 Central Nervous System Stimulants Phase 4
29 Antiemetics Phase 4
30 Gastrointestinal Agents Phase 4
31 Serotonin Uptake Inhibitors Phase 4
32 Antipsychotic Agents Phase 4
33
Quetiapine Fumarate Phase 4 111974-72-2
34 Cytochrome P-450 Enzyme Inhibitors Phase 4
35 Mitogens Phase 4
36 Anticoagulants Phase 4
37 Citrate Phase 4
38
Histamine phosphate Phase 4 51-74-1 134614
39 Histamine H1 Antagonists Phase 4
40 Histamine Antagonists Phase 4
41 Antirheumatic Agents Phase 4
42 Antipyretics Phase 4
43
Ketorolac Tromethamine Phase 4
44 Cyclooxygenase Inhibitors Phase 4
45 Anti-Inflammatory Agents, Non-Steroidal Phase 4
46 Immunoglobulins Phase 4
47 Antibodies Phase 4
48 Antibodies, Blocking Phase 4
49 Narcotics Phase 4
50 Narcotic Antagonists Phase 4

Interventional clinical trials:

(show top 50) (show all 996)
# Name Status NCT ID Phase Drugs
1 Study Proposal - A Randomized Double-blinded Study Comparing Adding Etoricoxib Versus Placebo to Female Patients With Fibromyalgia-analysis of Organic and Psychiatric Measures Unknown status NCT00755521 Phase 4 etoricoxib
2 Efficacy and Tolerability of Micronized and Ultramicronized Palmitoylethanolamide in Fibromyalgia Patients: A Double-blind, Randomized, Placebo-controlled Clinical Trial Unknown status NCT04488926 Phase 4 Standard Therapy;Rescue Drug
3 Low Dose Naltrexone for Treatment of Pain in Patients With Fibromyalgia - Effect Via a Central Mechanism? A Randomized, Double-blinded, Placebo-controlled, Crossover Study. Unknown status NCT02806440 Phase 4 Low dose naltrexone;Placebo
4 The Efficacy of Topical Thiocolchicoside in Cervical Myofascial Pain Syndrome: Triple-Arm, Single-Blind, Randomized, Prospective, Phase IV Clinical Study Completed NCT00272532 Phase 4 Thiocolchicoside
5 Treatment of Myofascial Pain Syndrome With Lidocaine Injection and Physical Therapy, Alone or in Combination: a Single-blind, Randomized, Controlled Clinical Trial. Completed NCT01250184 Phase 4 Lidocaine injection
6 Probe Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome Completed NCT00241215 Phase 4 Botulinum toxin serotype A
7 An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia Fatigue Completed NCT00678691 Phase 4 armodafinil;placebo
8 Ultracet (Tramadol HCL [37.5 mg]/Acetaminophen [325 mg]) Combination Tablets in the Treatment of the Pain of Fibromyalgia Completed NCT00766675 Phase 4 Tramadol hydrochloride;Acetaminophen
9 Magnesium Sulphate Injection in Treatment of Myofascial Trigger Points in Masseter Muscle Completed NCT04742140 Phase 4 Magnesium sulfate;Saline
10 Open Label Trial Concerning the Effectiveness of Trazodone in the Treatment of Fibromyalgia (Phase I) and Its Augmentation With Pregabalin in Trazodone Partial Responders (Phase II) Completed NCT00791739 Phase 4 trazodone, pregabalin
11 A Randomized, Pilot Clinical Trial to Assess the Comparative Efficacy and Tolerability of Quetiapine XR Versus Amitriptyline for the Treatment of Patients With Fibromyalgia Completed NCT00766350 Phase 4 amitriptyline;quetiapine
12 Pool-based Exercise in Fibromyalgia Management: a Prospective Randomized Comparison Between Stretching and Ai Chi Completed NCT00550641 Phase 4
13 Effectiveness of Strengthening Exercises Using the Swiss Ball for Patients With Fibromyalgia: a Randomized Controlled Trial Completed NCT02063750 Phase 4
14 A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and Tolerability of Quetiapine Fumarate Sustained Release(Seroquel SRTM) in the Treatment of Major Depression With Comorbid Fibromyalgia Syndrome. Completed NCT00675896 Phase 4 Quetiapine Fumarate Sustained Release;Placebo
15 Flexible Dosed Duloxetine Versus Placebo in the Treatment of Fibromyalgia Completed NCT00673452 Phase 4 duloxetine hydrochloride;placebo
16 Ambulatory Infusions of Lidocaine and Ketamine for Management of Chronic Pain: an Observational Prospective Study Completed NCT04123652 Phase 4 Lidocaine Hydrochloride 2% Intravenous Solution, DIN 02421992
17 Perception of Discomfort and Psychosocial Difficulties in People With Diagnosis of Fibromyalgia and Predominant Neck Pain Completed NCT02078791 Phase 4 Botox infiltration
18 The Study of Heart Rate Variability in Patients With Fibromyalgia - Effects of Strengthening Exercises Completed NCT02004405 Phase 4
19 Eszopiclone in the Treatment of Insomnia and Associated Symptoms of Fibromyalgia Completed NCT00392041 Phase 4 Eszopiclone;placebo
20 Combining N-of-1 Trials to Assess Fibromyalgia Therapies Completed NCT00000428 Phase 4 Amitriptyline;Amitriptyline plus Fluoxitine
21 A 6-month, Open-label, Safety Trial Of Pregabalin In Adolescent Patients With Fibromyalgia Completed NCT01020526 Phase 4 pregabalin
22 Plasma Rich in Growth Factors Effectiveness for Myofascial Pain Treatment in Masticatory Muscles: a Randomized Controlled Clinical Trial Completed NCT04040309 Phase 4 Lidocaine injection
23 A Randomized Controlled Trial Comparing the Efficay and Tolerability of Ai Chi Versus Stretching in Fibromyalgia Management: a Six Months Study Completed NCT00600574 Phase 4
24 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Switch Study to Evaluate the Safety, Tolerability and Efficacy of Milnacipran in Patients With an Inadequate Response to Duloxetine for the Treatment of Fibromyalgia Completed NCT01077375 Phase 4 Placebo;Milnacipran
25 A Pilot Study on the Combined Use of Cognitive Behavioral Therapy (CBT) and Milnacipran Completed NCT01038323 Phase 4 Educational with milnacipran
26 Paroxetine-CR (Paxil-CR) in the Treatment of Patients With Fibromyalgia Syndrome: A Randomized, Double Blind, Parallel Group, Flexible Dose, Placebo Controlled Trial. Completed NCT00610610 Phase 4 Paroxetine CR;Placebo
27 A Multicenter, Randomized, Double-blind, Placebo-Controlled Discontinuation Study of the Durability of Effect of Milnacipran for the Treatment of Fibromyalgia in Patients Receiving Long-term Milnacipran Treatment Completed NCT01014585 Phase 4 Placebo;Milnacipran
28 A Randomized, Double-Blind Comparison of Duloxetine 30 mg QD and Placebo in Adult Patients With Fibromyalgia Completed NCT00965081 Phase 4 Duloxetine;Placebo
29 An Open-Label Pilot Study to Assess Potential Mechanisms for Fibromyalgia in Peripheral Tissue Innervation That Could Predict Therapeutic Responsiveness to Milnacipran Completed NCT01125423 Phase 4 Milnacipran
30 Quetiapine (Seroquel XR) for the Treatment of Fibromyalgia: a Clinical and Mechanistic Pilot Study Completed NCT00983320 Phase 4 quetiapine;placebo
31 A Pilot Study on the Use of Nociceptive Flexion Reflex for Fibromyalgia Completed NCT00965601 Phase 4
32 A 15 Week, Randomized, Double Blind, Parallel-group, Placebo-controlled, Flexible-dose, Safety And Efficacy Study Of Pregabalin In Adolescents (12-17 Years Old) With Fibromyalgia Completed NCT01020474 Phase 4 placebo;pregabalin (Lyrica)
33 Randomized, Double-blind, Placebo-controlled Trial to Measure the Efficacy and Safety of Vitamin D3 in Patients With Fibromyalgia. Completed NCT03369379 Phase 4 D3 Vitamin
34 The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia Completed NCT01234675 Phase 4 Milnacipran;Placebo
35 Fixed Versus Flexible Dosing of Pregabalin in Patients With Fibromyalgia Completed NCT01226667 Phase 4 Pregabalin
36 A Randomized, Double-blind,Placebo-controlled, Two-way Crossover Study to Evaluate the Effect of Milnacipran on Pain Processing and Functional Magnetic Resonance Imaging Activation Patterns in Patients With Fibromyalgia Completed NCT01173055 Phase 4 milnacipran;Placebo
37 The Serotonin Receptor Type 3 Antagonist Granisetron as a New Treatment Approach for Patients With Chronic Myofascial Pain in the Orofacial Muscles Completed NCT02230371 Phase 4 Granisetron;Control (placebo)
38 Effects of a 12 Week Milnacipran 200 mg Treatment on Pain Perception and Pain Processing in Fibromyalgia - An Open Label Study Completed NCT01288807 Phase 4 Milnacipram
39 Quetiapine Compared With Placebo in the Management of Fibromyalgia Completed NCT01458964 Phase 4 Quetiapine
40 A Randomized, Single-dose, Parallel-group Study to Evaluate the Pharmacokinetic Profiles of Two Formulation of Pregabalin in Healthy Volunteers Under Fasting Conditions Completed NCT03712475 Phase 4 Pregabalin
41 Neurologic Signatures of Chronic Pain Disorders Completed NCT02747940 Phase 4 flunarizine and/or pregabalin
42 Trigger Point Injection for Myofascial Pain Syndrome in the Low Back (T-PIMPS): A Randomized Controlled Trial. Recruiting NCT04704297 Phase 4 Treatment of Myofascial Pain Syndrome in the low back. This intervention will be based on outcomes of the medications listed below.;Evaluation of functional ability using a patient centered functional score known as the Modified Oswestry Disability Index (MODI). The intervention will be based on outcomes of medications below.;Following up with participants 60-72 hours after treatment in the Emergency Department. This intervention will be based on outcomes of the medications listed below.
43 Evaluation of the Effect of Dextrose Prolotherapy on Pain and Function in Women With Myofascial Pain Syndrome Recruiting NCT04941118 Phase 4 Injection of dextrose, local anesthetic and saline to the myofascial trigger point;Local anesthetic and saline injection to the myofascial trigger point
44 A Randomized Controlled Study Comparing Trigger Point Injections With 1% Lidocaine Versus 5% Lidocaine Patch for Myofascial Pain in the Emergency Department Recruiting NCT05151510 Phase 4 Lidocaine patch 5%
45 Anti-CGRP Neutralizing Antibody for Modulation of Neurogenic Inflammation in Trigeminal and Glossopharyngeal Pain Associated With Small Fiber Neuropathy/Fibromyalgia Active, not recruiting NCT04158752 Phase 4 Galcanezumab
46 12-month Randomized, Double-blind, Placebo-controlled, Pharmacological Clinical Trial to Evaluate the Effectiveness, Cost-utility and Neurobiological Effects of Low-dose Naltrexone in Patients With Fibromyalgia (INNOVA Project) Enrolling by invitation NCT04739995 Phase 4 Low-dose naltrexone
47 Local Injection of Lidocaine Versus Ischemic Compression in Treatment of Woman With Chronic Pelvic Pain Caused by Abdominal Myofascial Pain Syndrome: Randomized Clinical Trial. Terminated NCT00628355 Phase 4 lidocaine
48 Using Saline for Myofascial Pain Syndromes (USAMPS) Terminated NCT02120261 Phase 4 Normal Saline;Lidocaine Hydrochloride;Triamcinolone acetonide
49 A Double-blind, Crossover, Study to Compare the Hypnotic, Daytime Sleepiness/Fatigue, and Pain Effects of Nighttime Administration of Suvorexant 20 mg Versus Placebo in Patients With Fibromyalgia and Comorbid Insomnia Terminated NCT02684136 Phase 4 suvorexant;placebo
50 An Eight Week, Double-Blind Efficacy Study of Cyclobenzaprine ER (Amrix TM) Augmentation to Alleviate Fibromyalgia Fatigue and Muscle Pain Terminated NCT01041495 Phase 4 cyclobenzaprine ER (AMRIX);placebo

Search NIH Clinical Center for Myofascial Pain Syndrome

Cochrane evidence based reviews: myofascial pain syndromes

Sources

Genetic Tests for Myofascial Pain Syndrome

About this section
Sources

Anatomical Context for Myofascial Pain Syndrome

About this section

Organs/tissues related to Myofascial Pain Syndrome:

MalaCards : Brain, Skeletal Muscle, Spinal Cord, Amygdala, Cortex, Pineal, Heart
Sources

Publications for Myofascial Pain Syndrome

About this section

Articles related to Myofascial Pain Syndrome:

(show top 50) (show all 996)
# Title Authors PMID Year
1
Potential Role of Insulin-Like Growth Factors in Myofascial Pain Syndrome: A Narrative Review. 62
35067552 2022
2
Guidance to trigger point injection for treating myofascial pain syndrome: Intramuscular neural distribution of the quadratus lumborum. 62
35655442 2022
3
Comparative Efficacy of Platelet-Rich Plasma and Dry Needling for Management of Trigger Points in Masseter Muscle in Myofascial Pain Syndrome Patients: A Randomized Controlled Trial. 62
36445907 2022
4
Clinical efficacy of electromagnetic field therapy combined with traditional Chinese pain-reducing paste in myofascial pain syndrome. 62
36405282 2022
5
Assessment of Concordance Between Chairside Ultrasonography and Digital Palpation in Detecting Myofascial Trigger Points in Masticatory Myofascial Pain Syndrome. 62
36455705 2022
6
Sonoanatomy and an ultrasound scanning protocol of the intramuscular innervation pattern of the infraspinatus muscle. 62
36427902 2022
7
Myofascial Pain Syndrome in Women with Primary Dysmenorrhea: A Case-Control Study. 62
36359567 2022
8
A randomized clinical trial of self-stretching with and without mindful breathing - immediate effect on pressure pain and range of motion in myofascial pain syndrome. 62
36180155 2022
9
Effectiveness of Photobiomodulation Therapy in the Treatment of Myofascial Pain Syndrome of the Upper Trapezius Muscle: A Systematic Review and Meta-Analysis. 62
36219747 2022
10
Ultrasound-Guided Trigger Point Injections for the Treatment of Neck and Back Pain in the Emergency Department: A Randomized Trial. 62
36214230 2022
11
An Atypical Path of the Lingual Nerve in the Retromolar Region: Incidence in Oral Surgery. 62
34287645 2022
12
Myofascial Trigger Points and Central Sensitization Signs, but No Anxiety, Are Shown in Women with Dysmenorrhea: A Case-Control Study. 62
36358253 2022
13
Visualizing Anatomic Variants of the Sciatic Nerve Using Diagnostic Ultrasound During Piriformis Muscle Injection: An Example of 4 Cases. 62
36118109 2022
14
Analgesic Electrical Stimulation Combined with Wrist-ankle Acupuncture Reduces the Cortical Response to Pain in Patients with Myofasciitis: A Randomized Clinical Trial. 62
36102803 2022
15
Clinical efficacy of magnesium sulfate injection in the treatment of masseter muscle trigger points: a randomized clinical study. 62
36123724 2022
16
Differential Sensitization of Muscle versus Fascia in Individuals with Low Back Pain. 62
36134986 2022
17
Silver Needle Thermal Therapy Relieves Pain, Repairs the Damaged Myofascial Fiber, and Reduces the Expression of 5-HT3 Receptors in the Spinal Cord of Rats with Myofascial Pain Syndrome. 62
36412383 2022
18
Effect of ischemic compression on myofascial pain syndrome: a systematic review and meta-analysis. 62
36050701 2022
19
Ultrasound-guided rhomboid intercostal block for myofascial pain syndrome: a prospective clinical study. 62
36422491 2022
20
Ultrasound-guided 3-in-1 trigger point injection for treating myofascial pain syndrome in muscles of the lateral scapular area: a case report. 62
35306823 2022
21
Therapeutic ultrasound versus injection of local anesthetic in the treatment of women with chronic pelvic pain secondary to abdominal myofascial syndrome: a randomized clinical trial. 62
35918696 2022
22
Efficacy and Effectiveness of Extracorporeal Shockwave Therapy in Patients with Myofascial Pain or Fibromyalgia: A Scoping Review. 62
36013480 2022
23
Trigger Point Injection as a Rare Cause of Ischemic Stroke: A Case Report. 62
34855672 2022
24
Prevalence of Myofascial Pain Syndrome and Efficacy of Trigger Point Injection in Patients with Incurable Cancer: A Multicenter, Prospective Observational Study (MyCar Study). 62
34940848 2022
25
Subacute postoperative myofascial pain diagnosed and treated successfully by ultrasound: a case after laparoscopic hepatectomy. 62
35852721 2022
26
Results of ultrasound-guided interfascial block of the trapezius muscle for myofascial pain. 62
35792700 2022
27
Interactions between the painful disorders and the autonomic nervous system. 62
35792695 2022
28
The role of acupuncture for myofascial pain syndrome (MPS) in interventional pain management. 62
35179004 2022
29
Neuralgia and Atypical Facial, Ear, and Head Pain. 62
35680205 2022
30
Diaphragmatic Mobility and Chest Expansion in Patients with Scapulocostal Syndrome: A Cross-Sectional Study. 62
35628087 2022
31
First Case of Occipital Neuralgia Treated by Fascial Hydrodissection. 62
35578561 2022
32
Molecular Mechanisms Underlying the Pain-Relieving Effects of Extracorporeal Shock Wave Therapy: A Focus on Fascia Nociceptors. 62
35629410 2022
33
Effect of dry-needling and exercise treatment on myofascial trigger point: A single-blind randomized controlled trial. 62
35272249 2022
34
Effect of ischemic compression performed by family caregivers on myofascial pain syndrome and the care burden of the families of patients: a multicenter open-label randomized comparative study. 62
34894707 2022
35
Intramuscular Innervation of the Supraspinatus Muscle Assessed Using Sihler's Staining: Potential Application in Myofascial Pain Syndrome. 62
35622557 2022
36
Myofascial pain syndrome and SARS-CoV-2: a case series. 62
34601951 2022
37
Intramuscular Neural Distribution of the Serratus Anterior Muscle: Regarding Botulinum Neurotoxin Injection for Treating Myofascial Pain Syndrome. 62
35448880 2022
38
The assessment of affective temperament and life quality in myofascial pain syndrome patients. 62
33084454 2022
39
Specialty-Specific Diagnoses in Pediatric Patients With Postconcussion Syndrome: Experience From a Multidisciplinary Concussion Clinic. 62
33605602 2022
40
Infrared Radiation in the Management of Musculoskeletal Conditions and Chronic Pain: A Systematic Review. 62
35323210 2022
41
Comparison of Dry Needling and Inhibitory Kinesio Taping in Treatment of Myofascial Pain Syndrome of the Upper Trapezius Muscle: A Randomized Controlled Trial. 62
35747613 2022
42
Efficacy of extracorporeal shock waves in the treatment of myofascial pain syndrome: a systematic review and meta-analysis of controlled clinical studies. 62
35280414 2022
43
Pain modulation induced by electronic wrist-ankle acupuncture: A functional near-infrared spectroscopy study. 62
34519161 2022
44
Effectiveness of intracavitary monopolar dielectric radiofrequency in women with endometriosis-associated pain: A case series. 62
34864492 2022
45
The efficacy of low-level diode laser versus laser acupuncture for the treatment of myofascial pain dysfunction syndrome (MPDS). 62
35169617 2022
46
Comparative Efficacy of Low-Level Laser Acupuncture and Cupping for Treatment of Patients with Myofascial Pain Dysfunction Syndrome: A Double-blinded, Randomized Clinical Trial: Comparison of the Effects of LLL Acupuncture and Cupping. 62
36408486 2022
47
Dry Needling Produces Mild Injuries Irrespective to Muscle Stiffness and Tension in Ex Vivo Mice Muscles. 62
35845982 2022
48
Scoping review and interpretation of myofascial pain/fibromyalgia syndrome: An attempt to assemble a medical puzzle. 62
35171940 2022
49
Altered Brain Activity and Effective Connectivity within the Nonsensory Cortex during Stimulation of a Latent Myofascial Trigger Point. 62
35992300 2022
50
Clinical Management of Chronic Pelvic Pain in Endometriosis Unresponsive to Conventional Therapy. 62
35055416 2022
Sources

Variations for Myofascial Pain Syndrome

About this section
Sources

Expression for Myofascial Pain Syndrome

About this section
Search GEO for disease gene expression data for Myofascial Pain Syndrome.
Sources

Pathways for Myofascial Pain Syndrome

About this section

Pathways related to Myofascial Pain Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
CREB Pathway 64
Show member pathways
 12.64 TRPV1 PDGFRB P2RX3 NGF BDNF
2
Sudden infant death syndrome (SIDS) susceptibility pathways 74
11.33 TAC1 NGF BDNF
3
SHP2 signaling 61
10.53 PDGFRB NGF BDNF
Sources

GO Terms for Myofascial Pain Syndrome

About this section

Cellular components related to Myofascial Pain Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 9.23 TAC1 P2RX3 NGF CALCA BDNF
2 obsolete intrinsic component of plasma membrane GO:0031226 8.96 TRPV1 PDGFRB

Biological processes related to Myofascial Pain Syndrome according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cytosolic calcium ion concentration GO:0007204 9.97 CALCA KNG1 TAC1 TRPV1
2 modulation of chemical synaptic transmission GO:0050804 9.85 P2RX3 NGF BDNF
3 cellular response to ATP GO:0071318 9.83 TRPV1 P2RX3
4 nerve development GO:0021675 9.8 NGF BDNF
5 cellular response to nerve growth factor stimulus GO:1990090 9.8 TRPV1 TAC1 CALCA
6 nerve growth factor signaling pathway GO:0038180 9.78 NGF BDNF
7 positive regulation of collateral sprouting GO:0048672 9.73 NGF BDNF
8 behavioral response to pain GO:0048266 9.69 TRPV1 P2RX3
9 detection of temperature stimulus involved in sensory perception of pain GO:0050965 9.63 TRPV1 CALCA ASIC3
10 urinary bladder smooth muscle contraction GO:0014832 9.58 TRPV1 P2RX3
11 detection of chemical stimulus involved in sensory perception of pain GO:0050968 9.56 TRPV1 ASIC3
12 response to pain GO:0048265 9.35 TRPV1 TAC1 CALCA
13 response to heat GO:0009408 9.17 TRPV1 P2RX3 CALCA ASIC3

Molecular functions related to Myofascial Pain Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.5 PDGFRB NGF KNG1 CALCA BDNF
2 nerve growth factor receptor binding GO:0005163 8.92 NGF BDNF
Sources

Sources for Myofascial Pain Syndrome

About this section
2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....