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MCID: MYF002
MIFTS: 42

Myofascial Pain Syndrome

Categories: Muscle diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Myofascial Pain Syndrome

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MalaCards integrated aliases for Myofascial Pain Syndrome:

Name: Myofascial Pain Syndrome 12 15 17
Myofascial Pain Syndromes 43 71
Myofascial Pain Dysfunction Syndrome 54
Fibromyalgia 71

Classifications:

MalaCards categories:
Anatomical: Muscle diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:431
MeSH 43 D009209
UMLS 71 C0016053 C0027073
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Summaries for Myofascial Pain Syndrome

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MalaCards based summary : Myofascial Pain Syndrome, also known as myofascial pain syndromes, is related to fibromyalgia and glossopharyngeal neuralgia, and has symptoms including muscle weakness, fatigue and myoclonus. An important gene associated with Myofascial Pain Syndrome is POMC (Proopiomelanocortin), and among its related pathways/superpathways is G alpha (s) signalling events. The drugs Histamine and Etoricoxib have been mentioned in the context of this disorder. Affiliated tissues include brain, breast and testes.

Wikipedia : 74 Myofascial pain syndrome (MPS), also known as chronic myofascial pain (CMP), is a syndrome characterized... more...

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Related Diseases for Myofascial Pain Syndrome

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Diseases related to Myofascial Pain Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 143)
# Related Disease Score Top Affiliating Genes
1 fibromyalgia 32.8 POMC CALCA BDNF
2 glossopharyngeal neuralgia 30.9 TAC1 POMC
3 facial neuralgia 30.6 TAC1 LAPTM4A
4 radiculopathy 30.4 TAC1 LAPTM4A HECTD4
5 frozen shoulder 30.4 LAPTM4A ASIC3
6 algoneurodystrophy 30.3 TAC1 NPS CALCA
7 complex regional pain syndrome 30.2 TAC1 POMC CALCA
8 hypochondriasis 29.8 POMC BDNF
9 reflex sympathetic dystrophy 29.7 TAC1 NPS HECTD4 CALCA
10 mental depression 29.7 POMC NPS BDNF
11 sleep disorder 29.5 POMC NPS BDNF
12 bursitis 29.5 TAC1 NDUFB8 LAPTM4A KNG1 HECTD4
13 anxiety 29.4 TAC1 POMC NPS BDNF
14 pulpitis 29.4 TRPV1 KNG1
15 trigeminal neuralgia 29.4 TRPV1 TAC1 NPS CALCA
16 irritable bowel syndrome 29.2 TRPV1 TAC1 POMC BDNF
17 major depressive disorder 29.1 TAC1 POMC NPS BDNF
18 paine syndrome 27.8 TRPV1 TAC1 NPS LAPTM4A KNG1 HECTD4
19 somatoform disorder 27.3 TRPV1 TAC1 NPS LAPTM4A KNG1 HECTD4
20 peripheral nervous system disease 27.1 TRPV1 TAC1 POMC NPS KNG1 HECTD4
21 chronic pain 10.6
22 trichorhinophalangeal syndrome 10.5
23 chronic fatigue syndrome 10.4
24 acute thyroiditis 10.4 POMC CALCA
25 arachnoiditis 10.4 TAC1 POMC
26 bruxism 10.4
27 lung oat cell carcinoma 10.4 POMC CALCA
28 colon neuroendocrine neoplasm 10.4 POMC CALCA
29 autonomic nervous system benign neoplasm 10.3 POMC CALCA
30 peripheral nervous system benign neoplasm 10.3 POMC CALCA
31 graves disease 1 10.3 POMC CALCA
32 aids phobia 10.3 TAC1 NPS
33 motion sickness 10.3 TAC1 POMC
34 interval angle-closure glaucoma 10.2 TAC1 KNG1
35 autonomic dysfunction 10.2
36 back pain 10.2
37 headache 10.2
38 patellofemoral pain syndrome 10.2 LAPTM4A HECTD4
39 neurogenic arthropathy 10.2 HECTD4 CALCA
40 neurodermatitis 10.2 TAC1 POMC NPS
41 achilles bursitis 10.2 SLC6A6 HECTD4
42 enthesopathy 10.2
43 spasticity 10.2
44 temporomandibular joint anomaly 10.1
45 periarthritis 10.1 NDUFB8 HECTD4
46 carbamazepine allergy 10.1 TAC1 NPS CALCA
47 hyperhidrosis, gustatory 10.1 TRPV1 TAC1
48 sick building syndrome 10.1 TRPV1 POMC
49 cough variant asthma 10.1 TRPV1 TAC1
50 carpal tunnel syndrome 10.1

Graphical network of the top 20 diseases related to Myofascial Pain Syndrome:



Diseases related to Myofascial Pain Syndrome
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Symptoms & Phenotypes for Myofascial Pain Syndrome

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UMLS symptoms related to Myofascial Pain Syndrome:


muscle weakness, fatigue, myoclonus, myalgia, back pain, torticollis, pain, chronic pain, sciatica, muscle cramp, muscle rigidity, muscle spasticity, myofascial trigger point pain
Sources

Drugs & Therapeutics for Myofascial Pain Syndrome

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Drugs for Myofascial Pain Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 297)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Histamine Approved, Investigational Phase 4 51-45-6 774
2
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
3
Flunarizine Approved Phase 4 52468-60-7 941361
4
Dinoprostone Approved Phase 4 363-24-6 5280360
5
Amitriptyline Approved Phase 4 50-48-6 2160
6
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
7
Perphenazine Approved Phase 4 58-39-9 4748
8
Eszopiclone Approved, Investigational Phase 4 138729-47-2 969472
9
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
10
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
11
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
12
Granisetron Approved, Investigational Phase 4 109889-09-0 3510
13
Citalopram Approved Phase 4 59729-33-8 2771
14
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
15
Clonazepam Approved, Illicit Phase 4 1622-61-3 2802
16
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
17
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
18
tannic acid Approved Phase 4 1401-55-4
19
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337
20
Sodium oxybate Approved Phase 4 502-85-2 5360545
21
Trazodone Approved, Investigational Phase 4 19794-93-5 5533
22
Promethazine Approved, Investigational Phase 4 60-87-7 4927
23
Suvorexant Approved, Investigational Phase 4 1030377-33-3
24
Diphenhydramine Approved, Investigational Phase 4 58-73-1, 147-24-0 3100
25
Naloxone Approved, Vet_approved Phase 4 465-65-6 5284596
26
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4 52485-79-7 40400 644073
27
Glutamic acid Approved, Nutraceutical Phase 4 56-86-0 33032
28
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 22737-96-8, 68-26-8, 11103-57-4 9904001 445354
29 Histamine Antagonists Phase 4
30 Histamine H1 Antagonists Phase 4
31
Histamine Phosphate Phase 4 51-74-1 65513
32 Cyclooxygenase 2 Inhibitors Phase 4
33 Nutrients Phase 4
34 Micronutrients Phase 4
35 Trace Elements Phase 4
36 Quetiapine Fumarate Phase 4 111974-72-2
37 Antipsychotic Agents Phase 4
38 Antiemetics Phase 4
39 Amitriptyline, perphenazine drug combination Phase 4
40 Cytochrome P-450 Enzyme Inhibitors Phase 4
41 Mitogens Phase 4
42 Antipyretics Phase 4
43 Hydrocortisone 17-butyrate 21-propionate Phase 4
44 Hydrocortisone hemisuccinate Phase 4
45 Cyclooxygenase Inhibitors Phase 4
46 Lisdexamfetamine Dimesylate Phase 4
47 Excitatory Amino Acid Antagonists Phase 4
48 Anesthetics, Dissociative Phase 4
49 Immunoglobulins Phase 4
50 Antibodies Phase 4

Interventional clinical trials:

(show top 50) (show all 1016)
# Name Status NCT ID Phase Drugs
1 Low Dose Naltrexone for Treatment of Pain in Patients With Fibromyalgia - Effect Via a Central Mechanism? A Randomized, Double-blinded, Placebo-controlled, Crossover Study. Unknown status NCT02806440 Phase 4 Low dose naltrexone;Placebo
2 An Eight Week, Double-Blind Efficacy Study of Cyclobenzaprine ER (Amrix TM) Augmentation to Alleviate Fibromyalgia Fatigue and Muscle Pain Unknown status NCT01041495 Phase 4 cyclobenzaprine ER (AMRIX);placebo
3 Study Proposal - A Randomized Double-blinded Study Comparing Adding Etoricoxib Versus Placebo to Female Patients With Fibromyalgia-analysis of Organic and Psychiatric Measures Unknown status NCT00755521 Phase 4 etoricoxib
4 Neurologic Signatures of Chronic Pain Disorders Unknown status NCT02747940 Phase 4 flunarizine and/or pregabalin
5 A Double-Blind, Placebo-Controlled, Enriched Enrollment Randomized Withdrawal Study to Evaluate the Efficacy of Milnacipran in the Treatment of Pain Due to Osteoarthritis Unknown status NCT01329406 Phase 4 Milnacipran;Placebo
6 The Impact of Perioperative Gabapentin on Chronic Groin Pain After Inguinal Hernia Repair Unknown status NCT02419443 Phase 4 Gabapentin;Placebo
7 The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain Unknown status NCT01417923 Phase 4 vitamin D
8 The Efficacy of Topical Thiocolchicoside in Cervical Myofascial Pain Syndrome: Triple-Arm, Single-Blind, Randomized, Prospective, Phase IV Clinical Study Completed NCT00272532 Phase 4 Thiocolchicoside
9 Treatment of Myofascial Pain Syndrome With Lidocaine Injection and Physical Therapy, Alone or in Combination: a Single-blind, Randomized, Controlled Clinical Trial. Completed NCT01250184 Phase 4 Lidocaine injection
10 A 6-month, Open-label, Safety Trial Of Pregabalin In Adolescent Patients With Fibromyalgia Completed NCT01020526 Phase 4 pregabalin
11 Quetiapine (Seroquel XR) for the Treatment of Fibromyalgia: a Clinical and Mechanistic Pilot Study Completed NCT00983320 Phase 4 quetiapine;placebo
12 A 15 Week, Randomized, Double Blind, Parallel-group, Placebo-controlled, Flexible-dose, Safety And Efficacy Study Of Pregabalin In Adolescents (12-17 Years Old) With Fibromyalgia Completed NCT01020474 Phase 4 placebo;pregabalin (Lyrica)
13 A Randomized, Double-Blind Comparison of Duloxetine 30 mg QD and Placebo in Adult Patients With Fibromyalgia Completed NCT00965081 Phase 4 Duloxetine;Placebo
14 Open Label Trial Concerning the Effectiveness of Trazodone in the Treatment of Fibromyalgia (Phase I) and Its Augmentation With Pregabalin in Trazodone Partial Responders (Phase II) Completed NCT00791739 Phase 4 trazodone, pregabalin
15 A Randomized, Pilot Clinical Trial to Assess the Comparative Efficacy and Tolerability of Quetiapine XR Versus Amitriptyline for the Treatment of Patients With Fibromyalgia Completed NCT00766350 Phase 4 amitriptyline;quetiapine
16 A Multicenter, Randomized, Double-blind, Placebo-Controlled Discontinuation Study of the Durability of Effect of Milnacipran for the Treatment of Fibromyalgia in Patients Receiving Long-term Milnacipran Treatment Completed NCT01014585 Phase 4 Placebo;Milnacipran
17 Flexible Dosed Duloxetine Versus Placebo in the Treatment of Fibromyalgia Completed NCT00673452 Phase 4 duloxetine hydrochloride;placebo
18 A Randomized Controlled Trial Comparing the Efficay and Tolerability of Ai Chi Versus Stretching in Fibromyalgia Management: a Six Months Study Completed NCT00600574 Phase 4
19 Eszopiclone in the Treatment of Insomnia and Associated Symptoms of Fibromyalgia Completed NCT00392041 Phase 4 Eszopiclone;placebo
20 The Effects of Milnacipran on Sleep Disturbance in Fibromyalgia Completed NCT01234675 Phase 4 Milnacipran;Placebo
21 Pool-based Exercise in Fibromyalgia Management: a Prospective Randomized Comparison Between Stretching and Ai Chi Completed NCT00550641 Phase 4
22 Quetiapine Compared With Placebo in the Management of Fibromyalgia Completed NCT01458964 Phase 4 Quetiapine
23 An Open-Label Pilot Study to Assess Potential Mechanisms for Fibromyalgia in Peripheral Tissue Innervation That Could Predict Therapeutic Responsiveness to Milnacipran Completed NCT01125423 Phase 4 Milnacipran
24 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Switch Study to Evaluate the Safety, Tolerability and Efficacy of Milnacipran in Patients With an Inadequate Response to Duloxetine for the Treatment of Fibromyalgia Completed NCT01077375 Phase 4 Placebo;Milnacipran
25 Fixed Versus Flexible Dosing of Pregabalin in Patients With Fibromyalgia Completed NCT01226667 Phase 4 Pregabalin
26 Effectiveness of Strengthening Exercises Using the Swiss Ball for Patients With Fibromyalgia: a Randomized Controlled Trial Completed NCT02063750 Phase 4
27 Ultracet (Tramadol HCL [37.5 mg]/Acetaminophen [325 mg]) Combination Tablets in the Treatment of the Pain of Fibromyalgia Completed NCT00766675 Phase 4 Tramadol hydrochloride;Acetaminophen
28 Probe Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome Completed NCT00241215 Phase 4 Botulinum toxin serotype A
29 Effects of a 12 Week Milnacipran 200 mg Treatment on Pain Perception and Pain Processing in Fibromyalgia - An Open Label Study Completed NCT01288807 Phase 4 Milnacipram
30 A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and Tolerability of Quetiapine Fumarate Sustained Release(Seroquel SRTM) in the Treatment of Major Depression With Comorbid Fibromyalgia Syndrome. Completed NCT00675896 Phase 4 Quetiapine Fumarate Sustained Release;Placebo
31 Perception of Discomfort and Psychosocial Difficulties in People With Diagnosis of Fibromyalgia and Predominant Neck Pain Completed NCT02078791 Phase 4 Botox infiltration
32 A Randomized, Double-blind,Placebo-controlled, Two-way Crossover Study to Evaluate the Effect of Milnacipran on Pain Processing and Functional Magnetic Resonance Imaging Activation Patterns in Patients With Fibromyalgia Completed NCT01173055 Phase 4 milnacipran;Placebo
33 An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia Fatigue Completed NCT00678691 Phase 4 armodafinil;placebo
34 A Pilot Study on the Combined Use of Cognitive Behavioral Therapy (CBT) and Milnacipran Completed NCT01038323 Phase 4 Educational with milnacipran
35 A Pilot Study on the Use of Nociceptive Flexion Reflex for Fibromyalgia Completed NCT00965601 Phase 4
36 Combining N-of-1 Trials to Assess Fibromyalgia Therapies Completed NCT00000428 Phase 4 Amitriptyline;Amitriptyline plus Fluoxitine
37 The Study of Heart Rate Variability in Patients With Fibromyalgia - Effects of Strengthening Exercises Completed NCT02004405 Phase 4
38 Paroxetine-CR (Paxil-CR) in the Treatment of Patients With Fibromyalgia Syndrome: A Randomized, Double Blind, Parallel Group, Flexible Dose, Placebo Controlled Trial. Completed NCT00610610 Phase 4 Paroxetine CR;Placebo
39 Randomized, Double-blind, Placebo-controlled Trial to Measure the Efficacy and Safety of Vitamin D3 in Patients With Fibromyalgia. Completed NCT03369379 Phase 4 D3 Vitamin
40 Plasma Rich in Growth Factors Effectiveness for Myofascial Pain Treatment in Masticatory Muscles: a Randomized Controlled Clinical Trial Completed NCT04040309 Phase 4 Lidocaine injection
41 The Serotonin Receptor Type 3 Antagonist Granisetron as a New Treatment Approach for Patients With Chronic Myofascial Pain in the Orofacial Muscles Completed NCT02230371 Phase 4 Granisetron;Control (placebo)
42 MuscleCareâ„¢ Pain Relief Therapy vs. Voltaren® in the Relief of Trapezius Trigger Point Musculoskeletal Pain. Completed NCT03939884 Phase 4 MuscleCare Topical Product;Voltaren Topical;Nivea, Topical Cream
43 A Randomized, Single-dose, Parallel-group Study to Evaluate the Pharmacokinetic Profiles of Two Formulation of Pregabalin in Healthy Volunteers Under Fasting Conditions Completed NCT03712475 Phase 4 Pregabalin
44 Patient Self-administration of Cortisol for Cortisol-responding Disorders in Men and Women Over the Age of 17, Demonstration of Double-blind Trial Results Completed NCT03558971 Phase 4 Cortisol
45 Use of Lisdexamfetamine Dimesylate in Treatment of Cognitive Impairment (Chronic Fatigue Syndrome): A Double Blind, Placebo Controlled Study Completed NCT01071044 Phase 4 Lisdexamfetamine Dimesylate;Placebo "30, 50 or 70 mg"
46 Milnacipran in the Treatment of Widespread, Non-Joint Pain in Rheumatoid Arthritis Completed NCT01207453 Phase 4 Milnacipran;Placebo
47 Efficacy of Pregabalin in Patients With Radicular Pain Completed NCT00908375 Phase 4 Pregabalin;Sugar Pill
48 An Open-Label Trial of Duloxetine for the Treatment of Irritable Bowel Syndrome Without Comorbid Major Depressive Disorder Completed NCT00401258 Phase 4 duloxetine
49 An Open Label Trial of Duloxetine in the Treatment of Irritable Bowel Syndrome and Comorbid Generalized Anxiety Disorder Completed NCT00961298 Phase 4 Duloxetine
50 Randomized Double-blind Study Comparing the Efficacy of Duloxetine With Placebo in Patients With Chronic Low Back Pain With a Radicular Component Completed NCT01166048 Phase 4 Duloxetine;Duloxetine

Search NIH Clinical Center for Myofascial Pain Syndrome

Cochrane evidence based reviews: myofascial pain syndromes

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Genetic Tests for Myofascial Pain Syndrome

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Anatomical Context for Myofascial Pain Syndrome

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MalaCards organs/tissues related to Myofascial Pain Syndrome:

40
Brain, Breast, Testes, Spinal Cord, Cortex, Heart, Skeletal Muscle
Sources

Publications for Myofascial Pain Syndrome

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Articles related to Myofascial Pain Syndrome:

(show top 50) (show all 758)
# Title Authors PMID Year
1
Ultrasound Imaging and Rehabilitation of Muscle Disorders: Part 2: Nontraumatic Conditions. 61
31764227 2020
2
Plasma rich in growth factors injection effectiveness for myofascial pain treatment in masticatory muscles. Randomised controlled trial. 61
32271467 2020
3
Sympathetic hyperinnervation in myofascial trigger points. 61
32087493 2020
4
Utilization of Botulinum Toxin for Musculoskeletal Disorders. 61
32516192 2020
5
The Effect of extracorporeal shock wave therapy on pain intensity and neck disability for patients with myofascial pain syndrome in the neck and shoulder: a meta-analysis of randomized controlled trials. 61
32520797 2020
6
Evaluation of Sensory Mapping of Erector Spinae Plane Block. 61
32517405 2020
7
Peripheral FGFR1 Regulates Myofascial Pain in Rats via the PI3K/AKT Pathway. 61
32278061 2020
8
Relative Effectiveness of Electroacupuncture and Biofeedback in the Treatment of Neck and Upper Back Myofascial Pain: A Randomized Clinical Trial. 61
31954696 2020
9
Spasticity-induced Pectoralis minor syndrome: a case-report. 61
31774031 2020
10
C4 radiculopathy misdiagnosed as myofascial pain syndrome in the upper trapezius. 61
32498538 2020
11
Erector spinae plane block for myofascial pain syndrome: only a short term relief? 61
32449341 2020
12
Authors' Reply: Letter to the Editor Regarding "The Effectiveness of Dry Needling and Exercise Therapy in Patients with Dizziness Caused by Cervical Myofascial Pain Syndrome; Prospective Randomized Clinical Study". 61
32358610 2020
13
Comments on Aydin et al: The Effectiveness of Dry Needling and Exercise Therapy in Patients with Dizziness Caused by Cervical Myofascial Pain Syndrome; a Prospective Randomized Clinical Study. 61
32358602 2020
14
Acute effects of myofascial induction technique in plantar fascia complex in patients with myofascial pain syndrome on postural sway and plantar pressures: A quasi-experimental study. 61
32114316 2020
15
[Effect of Resistance Exercise Program for Middle-Aged Women with Myofascial Pain Syndrome on Shoulder Pain, Angle of Shoulder Range of Motion, and Body Composition Randomized Controlled Trial, RCT]. 61
32376815 2020
16
Novel application of dry needling for neuropathic myofascial ankle pain and dysfunction following insidious integumentary infection: A case report. 61
32507139 2020
17
Ultrasound-guided Dextrose Injection Treatment for Chronic Myofascial Pain Syndrome: A Retrospective Case Series. 61
32349034 2020
18
Manual Therapy in the Treatment of Myofascial Pain Related to Temporomandibular Disorders: A Systematic Review. 61
32255579 2020
19
Efficacy of Extracorporeal Shockwave Therapy on Pain and Function in Myofascial Pain Syndrome of the Trapezius: A Systematic Review and Meta-Analysis. 61
32234411 2020
20
Improving characterization and diagnosis quality of Myofascial Pain Syndrome: a systematic review of the clinical and biomarker overlap with Delayed Onset Muscle Soreness. 61
32072791 2020
21
The effect of focused extracorporeal shock wave therapy on myofascial pain syndrome of trapezius: A systematic review and meta-analysis. 61
32049811 2020
22
Normal Saline Trigger Point Injections vs Conventional Active Drug Mix for Myofascial Pain Syndromes. 61
31477359 2020
23
Does low back pain or leg pain in gluteus medius syndrome contribute to lumbar degenerative disease and hip osteoarthritis and vice versa? A literature review. 61
32158082 2020
24
An Anatomical Basis for the Myofascial Trigger Points of the Abductor Hallucis Muscle. 61
32076620 2020
25
Dry Cupping, Ischemic Compression, or Their Combination for the Treatment of Trigger Points: A Pilot Randomized Trial. 61
31580695 2020
26
Ultrasound-Guided Subcostal TAP Block with Depot Steroids in the Management of Chronic Abdominal Pain Secondary to Chronic Pancreatitis: A Three-Year Prospective Audit in 54 Patients. 61
31560756 2020
27
[Myofascial trigger point: an indicator of acupoint sensitization]. 61
32144910 2020
28
Effect of Repetitive Transcranial Magnetic Stimulation on Pain Management: A Systematic Narrative Review. 61
32132973 2020
29
Ultrasound-Guided Inactivation of Trigger Points Combined with Muscle Fascia Stripping by Liquid Knife in Treatment of Postherpetic Neuralgia Complicated with Abdominal Myofascial Pain Syndrome: A Prospective and Controlled Clinical Study. 61
32509046 2020
30
Effect of Inhalation Aromatherapy on Pain, Anxiety, Comfort, and Cortisol Levels During Trigger Point Injection. 61
31567306 2020
31
Efficacy of Combination Therapies on Neck Pain and Muscle Tenderness in Male Patients with Upper Trapezius Active Myofascial Trigger Points. 61
32258159 2020
32
Fear Avoidance Beliefs and Kinesiophobia Are Presented in Athletes who Suffer from Gastrocnemius Chronic Myofascial Pain. 61
32003802 2020
33
Rhomboid intercostal block for myofascial pain syndrome in a patient with amyotrophic lateral sclerosis. 61
31334619 2019
34
Early results of supervised versus unsupervised rehabilitation of patients with cervical pain. 61
31177899 2019
35
Ultrasound-Guided Intermediate Cervical Plexus Block With Depot Steroids in the Management of Refractory Neck Pain Secondary to Cervicothoracic Myofascial Pain Syndrome: A Case Series. 61
31592828 2019
36
Myofascial Pain Syndrome: A Narrative Review Identifying Inconsistencies in Nomenclature. 61
31736284 2019
37
Ultrasound guided erector spinae plane block for myofascial pain syndrome. 61
30995595 2019
38
Feasibility of Ultrasound-Guided Trigger Point Injection in Patients with Myofascial Pain Syndrome. 61
31618922 2019
39
Effect of transcutaneous electrical acupuncture point stimulation on expression of p-JNK in the dorsal root ganglion in a rat model of myofascial pain syndrome. 61
31219313 2019
40
Comparison of intravenous NSAIDs and trigger point injection for low back pain in ED: A prospective randomized study. 61
30660342 2019
41
Effectiveness between Dry Needling and Ischemic Compression in the Triceps Surae Latent Myofascial Trigger Points of Triathletes on Pressure Pain Threshold and Thermography: A Single Blinded Randomized Clinical Trial. 61
31590390 2019
42
Efficacy of Topical Vibratory Stimulation for Reducing Pain During Trigger Point Injection to the Gastrocnemius: A Randomized Controlled Trial. 61
30926293 2019
43
Performance of the revised 2016 fibromyalgia diagnostic criteria in Korean patients with fibromyalgia. 61
31342642 2019
44
The Effect of Trigger Point Injections on Pain in Patients with Advanced Cancer. 61
31487973 2019
45
[Capsaicin topical cream (8%) for the treatment of myofascial pain syndrome]. 61
31519301 2019
46
Myofascial pain syndrome and trigger points: evaluation and treatment in patients with musculoskeletal pain. 61
31313700 2019
47
Interventions for myofascial pain syndrome in cancer pain: recent advances: why, when, where and how. 61
31348012 2019
48
Feasibility of a Support Vector Machine Classifier for Myofascial Pain Syndrome: Diagnostic Case-Control Study. 61
30614553 2019
49
Piriformis Syndrome: A Narrative Review of the Anatomy, Diagnosis, and Treatment. 61
31102324 2019
50
A systematic review of manual therapy techniques, dry cupping and dry needling in the reduction of myofascial pain and myofascial trigger points. 61
31563367 2019
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Variations for Myofascial Pain Syndrome

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Expression for Myofascial Pain Syndrome

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Search GEO for disease gene expression data for Myofascial Pain Syndrome.
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Pathways for Myofascial Pain Syndrome

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Pathways related to Myofascial Pain Syndrome according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
G alpha (s) signalling events 65
10.96 POMC NPS CALCA
Sources

GO Terms for Myofascial Pain Syndrome

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Biological processes related to Myofascial Pain Syndrome according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.95 TAC1 POMC PDGFRB NPS KNG1 CALCA
2 inflammatory response GO:0006954 9.83 TRPV1 TAC1 KNG1 CALCA
3 positive regulation of cytosolic calcium ion concentration GO:0007204 9.67 TRPV1 TAC1 KNG1 CALCA
4 regulation of blood pressure GO:0008217 9.63 TAC1 POMC CALCA
5 response to heat GO:0009408 9.58 TRPV1 CALCA ASIC3
6 glutamate secretion GO:0014047 9.55 TRPV1 BDNF
7 vasodilation GO:0042311 9.54 KNG1 CALCA
8 positive regulation of synaptic transmission, GABAergic GO:0032230 9.51 TAC1 NPS
9 negative regulation of heart rate GO:0010459 9.49 TRPV1 TAC1
10 neuropeptide signaling pathway GO:0007218 9.46 TAC1 POMC NPS CALCA
11 positive regulation of action potential GO:0045760 9.43 TAC1 NPS
12 cellular response to nerve growth factor stimulus GO:1990090 9.43 TRPV1 TAC1 CALCA
13 detection of chemical stimulus involved in sensory perception of pain GO:0050968 9.32 TRPV1 ASIC3
14 response to pain GO:0048265 9.13 TRPV1 TAC1 CALCA
15 detection of temperature stimulus involved in sensory perception of pain GO:0050965 8.8 TRPV1 CALCA ASIC3

Molecular functions related to Myofascial Pain Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.02 POMC PDGFRB KNG1 CALCA BDNF
Sources

Sources for Myofascial Pain Syndrome

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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