MYP17
MCID: MYP140
MIFTS: 19

Myopia 17, Autosomal Dominant (MYP17)

Categories: Eye diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Myopia 17, Autosomal Dominant

MalaCards integrated aliases for Myopia 17, Autosomal Dominant:

Name: Myopia 17, Autosomal Dominant 56 71
Myopia 17 56 13
Myopia 4, Formerly; Myp4, Formerly 56
Myopia 4, Formerly 56
Myp4, Formerly 56
Myp17 56

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant


HPO:

31
myopia 17, autosomal dominant:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 56 608367
OMIM Phenotypic Series 56 PS160700
MedGen 41 C3888211
UMLS 71 C3888211

Summaries for Myopia 17, Autosomal Dominant

OMIM : 56 Myopia, or nearsightedness, is a refractive error of the eye. Light rays from a distant object are focused in front of the retina and those from a near object are focused in the retina; therefore distant objects are blurry and near objects are clear (summary by Kaiser et al., 2004). For a discussion of genetic heterogeneity of susceptibility to myopia, see 160700. (608367)

MalaCards based summary : Myopia 17, Autosomal Dominant, also known as myopia 17, is related to myopia. An important gene associated with Myopia 17, Autosomal Dominant is MYP17 (Myopia 17). Affiliated tissues include retina and eye, and related phenotypes are high myopia and presenile cataracts

Related Diseases for Myopia 17, Autosomal Dominant

Symptoms & Phenotypes for Myopia 17, Autosomal Dominant

Human phenotypes related to Myopia 17, Autosomal Dominant:

31
# Description HPO Frequency HPO Source Accession
1 high myopia 31 HP:0011003
2 presenile cataracts 31 HP:0007819
3 retinal hole 31 HP:0011530

Symptoms via clinical synopsis from OMIM:

56
Head And Neck Eyes:
presenile cataract
myopia, high-grade bilateral (range -5.50 to -50 diopters, average adult refractive error -13.925 diopters)
increased ocular axial length (35 mm vs. 24 mm in normal non-myopes)
multiple retinal holes

Clinical features from OMIM:

608367

Drugs & Therapeutics for Myopia 17, Autosomal Dominant

Search Clinical Trials , NIH Clinical Center for Myopia 17, Autosomal Dominant

Genetic Tests for Myopia 17, Autosomal Dominant

Anatomical Context for Myopia 17, Autosomal Dominant

MalaCards organs/tissues related to Myopia 17, Autosomal Dominant:

40
Retina, Eye

Publications for Myopia 17, Autosomal Dominant

Articles related to Myopia 17, Autosomal Dominant:

(show all 11)
# Title Authors PMID Year
1
Genomewide scan of ocular refraction in African-American families shows significant linkage to chromosome 7p15. 56
18293391 2008
2
Linkage analysis of high myopia susceptibility locus in 26 families. 56
19122830 2008
3
Confirmation of linkage to ocular refraction on chromosome 22q and identification of a novel linkage region on 1q. 56
17210856 2007
4
A genome wide scan for familial high myopia suggests a novel locus on chromosome 7q36. 56
11836361 2002
5
The prevalence of visual disorders in Iranian students: A meta-analysis study and systematic review. 61
29238492 2017
6
Intravitreal bevacizumab for retinopathy of prematurity: refractive error results. 61
23490192 2013
7
Pediatric rhegmatogenous retinal detachment: clinical features and surgical outcomes. 61
18536601 2008
8
The aetiology of paediatric rhegmatogenous retinal detachment: 15 years experience. 61
17293792 2008
9
Refractive changes during 72-hour exposure to high altitude after refractive surgery. 61
8764786 1996
10
Retreatment after excimer laser photorefractive keratectomy. The Melbourne Excimer Laser Group. 61
8597267 1996
11
Limited retinal detachment. A retrospective analysis of treatment with transconjunctival retinocryopexy. 61
3951828 1986

Variations for Myopia 17, Autosomal Dominant

Expression for Myopia 17, Autosomal Dominant

Search GEO for disease gene expression data for Myopia 17, Autosomal Dominant.

Pathways for Myopia 17, Autosomal Dominant

GO Terms for Myopia 17, Autosomal Dominant

Sources for Myopia 17, Autosomal Dominant

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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