MYP7
MCID: MYP040
MIFTS: 20

Myopia 7 (MYP7)

Categories: Eye diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Myopia 7

MalaCards integrated aliases for Myopia 7:

Name: Myopia 7 56 13 71
Myp7 56

Characteristics:

OMIM:

56
Inheritance:
multifactorial


Classifications:



External Ids:

OMIM 56 609256
OMIM Phenotypic Series 56 PS160700
MedGen 41 C1836506
SNOMED-CT via HPO 68 57190000
UMLS 71 C1836506

Summaries for Myopia 7

OMIM : 56 Myopia, or nearsightedness, is a refractive error of the eye. Light rays from a distant object are focused in front of the retina and those from a near object are focused in the retina; therefore distant objects are blurry and near objects are clear (summary by Kaiser et al., 2004). For a discussion of genetic heterogeneity of susceptibility to myopia, see 160700. (609256)

MalaCards based summary : Myopia 7, also known as myp7, is related to myopia. An important gene associated with Myopia 7 is MYP7 (Myopia 7). The drugs Atropine and Caffeine have been mentioned in the context of this disorder. Affiliated tissues include retina and eye, and related phenotype is myopia.

Related Diseases for Myopia 7

Symptoms & Phenotypes for Myopia 7

Human phenotypes related to Myopia 7:

31
# Description HPO Frequency HPO Source Accession
1 myopia 31 HP:0000545

Symptoms via clinical synopsis from OMIM:

56
Head And Neck Eyes:
myopia, low to moderate (-12.12 d to +7.25 d)

Clinical features from OMIM:

609256

Drugs & Therapeutics for Myopia 7

Drugs for Myopia 7 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Atropine Approved, Vet_approved Phase 1 51-55-8, 5908-99-6 174174
2
Caffeine Approved Phase 1 58-08-2 2519
3 Anti-Arrhythmia Agents Phase 1
4 Neurotransmitter Agents Phase 1
5 Respiratory System Agents Phase 1
6 Adjuvants, Anesthesia Phase 1
7 Anesthetics Phase 1
8 Muscarinic Antagonists Phase 1
9 Anti-Asthmatic Agents Phase 1
10 Parasympatholytics Phase 1
11 Pharmaceutical Solutions Phase 1
12 Ophthalmic Solutions Phase 1
13 Cholinergic Agents Phase 1
14 Bronchodilator Agents Phase 1
15 Cholinergic Antagonists Phase 1
16 Autonomic Agents Phase 1
17 Mydriatics Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase 2 Study of the Effect of 7-Methylxanthine on the Progression of Childhood Myopia Unknown status NCT00263471 Phase 2 7-methylxanthine
2 A One-month, Randomized, Single Centre, Double-masked, Comparative Study to Evaluate the Short-term Ocular Effects of Experimental BHVI2 and 0.02% Atropine Eye Drops Either Alone or in Combination Active, not recruiting NCT03690414 Phase 1 Experimental BHVI2;Atropine sulfate 0.02% eye drops

Search NIH Clinical Center for Myopia 7

Genetic Tests for Myopia 7

Anatomical Context for Myopia 7

MalaCards organs/tissues related to Myopia 7:

40
Retina, Eye

Publications for Myopia 7

Articles related to Myopia 7:

(show all 11)
# Title Authors PMID Year
1
A susceptibility locus for myopia in the normal population is linked to the PAX6 gene region on chromosome 11: a genomewide scan of dizygotic twins. 56
15307048 2004
2
Exome genotyping and linkage analysis identifies two novel linked regions and replicates two others for myopia in Ashkenazi Jewish families. 61
30704416 2019
3
A randomized controlled trial of peeling and aspiration of Elschnig pearls and neodymium: yttrium-aluminium-garnet laser capsulotomy. 61
26086014 2015
4
Dissecting the genetic heterogeneity of myopia susceptibility in an Ashkenazi Jewish population using ordered subset analysis. 61
21738393 2011
5
AC and AG dinucleotide repeats in the PAX6 P1 promoter are associated with high myopia. 61
19907666 2009
6
A critical evaluation of the evidence supporting the practice of behavioural vision therapy. 61
19154276 2009
7
Genetic mapping of myopia susceptibility loci. 61
17962440 2007
8
Familial pathologic myopia, corneal dystrophy, and deafness: a new syndrome. 61
11754903 2001
9
[Analysis of energy levels for Nd:YAG laser capsulotomy in secondary cataract]. 61
10663781 2000
10
[Epikeratophakia surgery for refractive errors and keratoconus]. 61
2613086 1989
11
Epikeratoplasty for adult and pediatric aphakia, myopia, and keratoconus: the Massachusetts Eye and Ear Infirmary experience. 61
2554656 1989

Variations for Myopia 7

Expression for Myopia 7

Search GEO for disease gene expression data for Myopia 7.

Pathways for Myopia 7

GO Terms for Myopia 7

Sources for Myopia 7

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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