MCID: MYP060
MIFTS: 21

Myopic Macular Degeneration

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Myopic Macular Degeneration

MalaCards integrated aliases for Myopic Macular Degeneration:

Name: Myopic Macular Degeneration 58 17 71
Myopic Maculopathy 58

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 58  
Rare eye diseases


External Ids:

ICD10 via Orphanet 33 H35.3
UMLS via Orphanet 72 C0730271
Orphanet 58 ORPHA178493
UMLS 71 C0730271

Summaries for Myopic Macular Degeneration

MalaCards based summary : Myopic Macular Degeneration, also known as myopic maculopathy, is related to macular degeneration, age-related, 1 and joint laxity, short stature, and myopia. The drugs Atropine and Respiratory System Agents have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and retina.

Related Diseases for Myopic Macular Degeneration

Diseases related to Myopic Macular Degeneration via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 15)
# Related Disease Score Top Affiliating Genes
1 macular degeneration, age-related, 1 10.7
2 joint laxity, short stature, and myopia 10.5
3 myopia 10.5
4 macular holes 10.4
5 eye disease 10.2
6 scotoma 10.2
7 retinal detachment 10.1
8 yemenite deaf-blind hypopigmentation syndrome 10.1
9 myopia 6 10.1
10 refractive error 10.1
11 48,xyyy 10.1
12 retinoschisis 1, x-linked, juvenile 10.1
13 degenerative myopia 10.1
14 optic nerve disease 10.1
15 vitreous detachment 10.1

Graphical network of the top 20 diseases related to Myopic Macular Degeneration:



Diseases related to Myopic Macular Degeneration

Symptoms & Phenotypes for Myopic Macular Degeneration

Drugs & Therapeutics for Myopic Macular Degeneration

Drugs for Myopic Macular Degeneration (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Atropine Approved, Vet_approved Phase 2 51-55-8, 5908-99-6 174174
2 Respiratory System Agents Phase 2
3 Parasympatholytics Phase 2
4 Cholinergic Agents Phase 2
5 Anti-Asthmatic Agents Phase 2
6 Anti-Arrhythmia Agents Phase 2
7 Muscarinic Antagonists Phase 2
8 Cholinergic Antagonists Phase 2
9 Neurotransmitter Agents Phase 2
10 Ophthalmic Solutions Phase 2
11 Bronchodilator Agents Phase 2
12 Mydriatics Phase 2

Interventional clinical trials:

(show all 12)
# Name Status NCT ID Phase Drugs
1 Low-dose Atropine for the Prevention of Myopia Progression in Danish Children - a Randomized, Double-masked, Multicenter, 36-month Prospective 1:1:1 Study of Safety and Efficacy of 0.1% Atropine Loading Dose to Single 0.01% Atropine and Placebo Recruiting NCT03911271 Phase 2 0.1% atropine and 0.01% atropine;0.01% atropine;0.9% Sodium-chloride
2 A Phase I/II, Open-Label, Prospective Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (MA09-hRPE) Cells in Patients With Geographic Atrophy Secondary to Myopic Macular Degeneration Withdrawn NCT02122159 Phase 1, Phase 2
3 Visual Rehabilitation of Patients With Myopic Maculopathy Completed NCT01244074
4 Correlation Between Choroidal Thickness and Myopia Using Swept Source OCT Completed NCT03542448
5 ¿Es Util la Acupuntura en la Degeneracion Macular? Prospective Study of Efficacy of Acupuncture in Macular Diseases Completed NCT02255981
6 Bone Marrow Derived Stem Cell Ophthalmology Treatment Study II Recruiting NCT03011541
7 Does Specialty Soft Contact Lens Wear Decrease the Onset and Progression of Myopia in Optometry School Interns? Active, not recruiting NCT04334369
8 Near Visual Acuity and Quality of Life Improvement After Implantation of the add-on Scharioth Macula Lens (SML, Medicontur) in Patients With Dry Age-related Macular Degeneration and Myopic Maculopathy Enrolling by invitation NCT03882606
9 Bone Marrow Derived Stem Cell Ophthalmology Treatment Study Enrolling by invitation NCT01920867
10 Myopia Progression in Children and Adolescents Before and After Use of a Novel Extended Depth of Focus Daily Disposable Soft Contact Lens Enrolling by invitation NCT03358862
11 Shanghai Child and Adolescent Large-scale Eye Study -High Myopia Registration Enrolling by invitation NCT03666052
12 Myopia Progression in Children Wearing Near Center and Distance Center Multifocals - a Randomized Controlled Clinical Trial Withdrawn NCT03519490

Search NIH Clinical Center for Myopic Macular Degeneration

Genetic Tests for Myopic Macular Degeneration

Anatomical Context for Myopic Macular Degeneration

MalaCards organs/tissues related to Myopic Macular Degeneration:

40
Eye, Bone, Retina, Endothelial

Publications for Myopic Macular Degeneration

Articles related to Myopic Macular Degeneration:

(show top 50) (show all 170)
# Title Authors PMID Year
1
Quantitative assessment of the retinal microvasculature and choriocapillaris in myopic patients using swept-source optical coherence tomography angiography. 61
32144487 2020
2
Progression of myopic maculopathy in a Caucasian cohort of highly myopic patients with long follow-up: a multistate analysis. 61
32564136 2020
3
Three-year outcomes of macular buckling for macular holes and foveoschisis in highly myopic eyes. 61
31742899 2020
4
How does spending time outdoors protect against myopia? A review. 61
31722876 2020
5
Characteristics of myopic traction maculopathy in myopic Singaporean adults. 61
32447325 2020
6
Treatment of macular hole retinal detachment with macular plug in highly myopic eyes: three-year results. 61
32243725 2020
7
The Complications of Myopia: A Review and Meta-Analysis. 61
32347918 2020
8
Six-Year Changes in Myopic Macular Degeneration in Adults of the Singapore Epidemiology of Eye Diseases Study. 61
32298432 2020
9
Prevalence of myopic macular degeneration worldwide: a systematic review and meta-analysis. 61
32188679 2020
10
Prevalence of Myopic Maculopathy Among Adults in a Russian Population. 61
32142129 2020
11
Permanent visual work disabilities: 321 cases review. 61
32035740 2020
12
Risk factors for subretinal fibrosis after anti-VEGF treatment of myopic choroidal neovascularisation. 61
32161005 2020
13
MORPHOLOGICAL CHARACTERISTICS AND VISUAL ACUITY OF HIGHLY MYOPIC EYES WITH DIFFERENT SEVERITIES OF MYOPIC MACULOPATHY. 61
30576301 2020
14
Histology of myopic posterior scleral staphylomas. 61
32190987 2020
15
Prognostic Factors Related with Surgical Outcome of Vitrectomy in Myopic Traction Maculopathy. 61
32037751 2020
16
RIDGE-SHAPED MACULA IN YOUNG MYOPIC PATIENTS AND ITS DIFFERENTIATION FROM TYPICAL DOME-SHAPED MACULA IN ELDERLY MYOPIC PATIENTS. 61
31972791 2020
17
VALIDATION OF THE RECENTLY DEVELOPED ATN CLASSIFICATION AND GRADING SYSTEM FOR MYOPIC MACULOPATHY. 61
32073545 2020
18
Patchy Scotoma Observed in Chorioretinal Patchy Atrophy of Myopic Macular Degeneration. 61
32053726 2020
19
A review on the epidemiology of myopia in school children worldwide. 61
31937276 2020
20
Morphological Characteristics and Risk Factors of Myopic Maculopathy in an Older High Myopia Population-Based on the New Classification System (ATN). 61
31351050 2019
21
Prevalence of myopic maculopathy in the German population: results from the Gutenberg health study. 61
31843792 2019
22
Prevalence and risk factors of myopic maculopathy in rural southern China: the Yangxi Eye Study. 61
30770357 2019
23
Association between Axial Length and Myopic Maculopathy: The Hisayama Study. 61
31202664 2019
24
Correlation of axial length and myopic macular degeneration to levels of molecular factors in the aqueous. 61
31673022 2019
25
CHARACTERIZATION OF THE CHOROIDAL VASCULATURE IN MYOPIC MACULOPATHY WITH OPTICAL COHERENCE TOMOGRAPHIC ANGIOGRAPHY. 61
29952919 2019
26
Influence of myopic macular degeneration severity on treatment outcomes with intravitreal aflibercept in the MYRROR study. 61
30690902 2019
27
SURGICAL OUTCOMES OF MYOPIC TRACTION MACULOPATHY ACCORDING TO THE INTERNATIONAL PHOTOGRAPHIC CLASSIFICATION FOR MYOPIC MACULOPATHY. 61
31453929 2019
28
Trends in the Prevalence of Myopia and Myopic Maculopathy in a Japanese Population: The Hisayama Study. 61
31260519 2019
29
Tessellated fundus appearance and its association with myopic refractive error. 61
30091794 2019
30
OCT-Based Diagnostic Criteria for Different Stages of Myopic Maculopathy. 61
30703442 2019
31
Myopia Control: Why Each Diopter Matters. 61
31116165 2019
32
POSTERIOR FUNDUS HEMORRHAGES: Frequency and Associated Factors: The Beijing Eye Study. 61
29533284 2019
33
[Epidemiology and anatomy of myopia]. 61
30796602 2019
34
CORRELATIONS BETWEEN EXPERIMENTAL MYOPIA MODELS AND HUMAN PATHOLOGIC MYOPIA. 61
30586351 2019
35
Visual rehabilitation using microperimetric acoustic biofeedback training in individuals with central scotoma. 61
30253443 2019
36
Progression of Myopic Maculopathy in Highly Myopic Chinese Eyes. 61
30901386 2019
37
Potential Lost Productivity Resulting from the Global Burden of Myopia: Systematic Review, Meta-analysis, and Modeling. 61
30342076 2019
38
We can't afford to turn a blind eye to myopia. 61
30911761 2019
39
Myopic maculopathy: Current status and proposal for a new classification and grading system (ATN). 61
30391362 2019
40
Imaging of Pathologic Myopia. 61
30924327 2019
41
Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium. 61
31415580 2019
42
Correction: Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium. 61
31600355 2019
43
Retinal Vasculature and Microstructure in Early Dry-Type Myopic Maculopathy. 61
31467694 2019
44
Axial length and its associations in a Russian population: The Ural Eye and Medical Study. 61
30707718 2019
45
Observational study of clinical characteristics of dome-shaped macula in Chinese Han with high myopia at Zhongshan Ophthalmic Centre. 61
30580257 2018
46
Reducing the impact of the impending myopia epidemic in New Zealand. 61
30543614 2018
47
Diagnosis and Treatment of Myopic Maculopathy. 61
30255668 2018
48
RIDGE-SHAPED MACULA IN YOUNG MYOPIC PATIENTS AND ITS DIFFERENTIATION FROM TYPICAL DOME-SHAPED MACULA IN ELDERLY MYOPIC PATIENTS. 61
30475289 2018
49
Distribution and Severity of Myopic Maculopathy Among Highly Myopic Eyes. 61
30347081 2018
50
Longitudinal Changes in Disc and Retinal Lesions Among Highly Myopic Adolescents in Singapore Over a 10-Year Period. 61
29369230 2018

Variations for Myopic Macular Degeneration

Expression for Myopic Macular Degeneration

Search GEO for disease gene expression data for Myopic Macular Degeneration.

Pathways for Myopic Macular Degeneration

GO Terms for Myopic Macular Degeneration

Sources for Myopic Macular Degeneration

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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