Aliases & Classifications for Myxosarcoma

MalaCards integrated aliases for Myxosarcoma:

Name: Myxosarcoma 12 43 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:4136
MeSH 43 D009236
NCIt 49 C3255
SNOMED-CT 67 28351005
UMLS 71 C0027155

Summaries for Myxosarcoma

MalaCards based summary : Myxosarcoma is related to fibroma and neurofibrosarcoma. An important gene associated with Myxosarcoma is MB (Myoglobin), and among its related pathways/superpathways are Sphingolipid metabolism and Phospholipase D signaling pathway. The drugs Fluorouracil and Parathyroid hormone have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and lung.

Wikipedia : 74 Myxosarcoma is a rare malignant tumor of the... more...

Related Diseases for Myxosarcoma

Diseases related to Myxosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 fibroma 30.0 S100A1 PECAM1
2 neurofibrosarcoma 10.2 S100A1 MXD3
3 carney complex variant 10.2
4 pulmonary hypertension 10.2
5 chondroma 10.2
6 congestive heart failure 10.2
7 posttransplant acute limbic encephalitis 10.2
8 bartholin's duct cyst 10.1 MXD3 CALD1
9 malignant mesenchymoma 10.1 MB CALD1
10 breast leiomyosarcoma 10.1 MB CALD1
11 conventional fibrosarcoma 10.1 MB CALD1
12 glomus tumor 10.1 S100A1 CALD1
13 epithelioid leiomyosarcoma 10.1 MB CALD1
14 intussusception 10.0
15 otitis media 10.0
16 chordoma 10.0
17 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.0
18 yemenite deaf-blind hypopigmentation syndrome 10.0
19 hemiplegia 10.0
20 pulmonary edema 10.0
21 hemopericardium 10.0
22 pericardial effusion 10.0
23 diarrhea 10.0
24 pericarditis 10.0
25 bronchiolo-alveolar adenocarcinoma 10.0
26 heart sarcoma 10.0
27 adrenal adenoma 10.0
28 adenoma 10.0
29 hyperthyroidism 10.0
30 exophthalmos 10.0
31 intracranial hypertension 10.0
32 stomatitis 10.0
33 odontogenic myxoma 10.0
34 aneurysm 10.0
35 back pain 10.0
36 cerebral aneurysms 10.0
37 foot drop 10.0
38 syncope 10.0
39 rare tumor 10.0
40 intestinal polyposis syndrome 10.0
41 infantile myofibromatosis 10.0 MB CALD1
42 myofibroma 10.0 S100A1 MB CALD1
43 dedifferentiated liposarcoma 9.9 S100A1 MB CALD1
44 intravascular angioleiomyoma 9.8 PECAM1 CALD1
45 leiomyosarcoma 9.8 S100A1 PECAM1 MB
46 angiomyoma 9.7 PECAM1 CALD1
47 glomangiosarcoma 9.7 PECAM1 CALD1
48 benign perivascular tumor 9.7 PECAM1 CALD1
49 cavernous hemangioma 9.7 S100A1 PECAM1 MB
50 sarcomatoid squamous cell skin carcinoma 9.7 PECAM1 CALD1

Graphical network of the top 20 diseases related to Myxosarcoma:



Diseases related to Myxosarcoma

Symptoms & Phenotypes for Myxosarcoma

Drugs & Therapeutics for Myxosarcoma

Drugs for Myxosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fluorouracil Approved Phase 1 51-21-8 3385
2
Parathyroid hormone Approved, Investigational Phase 1 9002-64-6
3
Belinostat Approved, Investigational Phase 1 866323-14-0
4 Immunologic Factors Phase 1
5 Histone Deacetylase Inhibitors Phase 1
6 Androgens Phase 1
7 Immunosuppressive Agents Phase 1
8 Antimetabolites Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase I Safety, Pharmacodynamic, Anti-Tumor Activity, and Pharmacokinetic Study of PXD101 Alone and in Combination With 5-Fluorouracil in Patients With Advanced Solid Tumors Completed NCT00413322 Phase 1 belinostat;5-Fluorouracil (5-FU)

Search NIH Clinical Center for Myxosarcoma

Cochrane evidence based reviews: myxosarcoma

Genetic Tests for Myxosarcoma

Anatomical Context for Myxosarcoma

MalaCards organs/tissues related to Myxosarcoma:

40
Heart, Brain, Lung, Breast, Bone, Spleen, Skin

Publications for Myxosarcoma

Articles related to Myxosarcoma:

(show top 50) (show all 158)
# Title Authors PMID Year
1
Obstructive right ventricular outflow tract myxosarcoma in an adult dog. 61
32464578 2020
2
Neuropathogenicity of newly isolated avian leukosis viruses from chickens with osteopetrosis and mesenchymal neoplasms. 61
32301629 2020
3
Myxosarcoma Associated with the Kidney in a Cat: Case Report. 61
31961219 2020
4
An extraskeletal osteosarcoma in the auricle of a Wistar Hannover rat. 61
31404367 2019
5
Canine myxosarcomas, a retrospective analysis of 32 dogs (2003-2018). 61
31248415 2019
6
TAENIA CRASSICEPS CYSTICERCOSIS IN A NILGIRI LANGUR ( SEMNOPITHECUS JOHNII). 61
29900783 2018
7
MHC-B haplotypes impact susceptibility and resistance to RSV-A infection. 61
29772523 2018
8
Extracardiac intrapericardial myxosarcoma causing right ventricular outflow tract obstruction in a dog. 61
29500126 2018
9
Retrobulbar malignant peripheral nerve sheath tumor in a golden retriever dog: A challenging diagnosis. 61
29606723 2018
10
Metastatic myxosarcoma in a Quarter Horse gelding. 61
28677418 2018
11
Charcot-Leyden crystals: do they exist in veterinary species? A case report and literature review. 61
28782436 2017
12
Clinical, computed tomographic, magnetic resonance imaging, and histologic findings associated with myxomatous neoplasia of the temporomandibular joint in two dogs. 61
27875090 2016
13
What Is Your Diagnosis? Myxosarcoma in a cat. 61
26331415 2015
14
Metronomic Chemotherapy for Myxosarcoma Treatment in a Kori Bustard (Ardeotis kori). 61
26378667 2015
15
Canine low-grade intra-orbital myxosarcoma: case report. 61
24837165 2015
16
Myxosarcoma of the maxilla - a case report. 61
25954712 2015
17
Multiple intra-abdominal serosal myxosarcomas in two koalas (Phascolarctos cinereus). 61
25728815 2015
18
Long-term survival after extended resection of primary atrial myxosarcoma. 61
25583907 2015
19
What is your diagnosis? Grade 2 myxosarcoma of the subcutis and bone. 61
25406700 2014
20
Axillary artery tumor embolism secondary to mitral valve myxosarcoma in a dog. 61
25471647 2014
21
Diagnosis and treatment of a periocular myxosarcoma in a bearded dragon (Pogona vitticeps). 61
24982518 2014
22
Cardiac myxosarcoma with thoracic spinal metastasis. 61
23677508 2014
23
One hundred two tumors in 100 goats (1987-2011). 61
23341420 2013
24
What is your diagnosis? Low-grade myxosarcoma arising from the heart valve. 61
23547667 2013
25
Intrathoracic myxosarcoma in a dog. 61
22520813 2012
26
Primary and metastatic cardiac sarcomas: a 12-year experience at a German heart center. 61
23119110 2012
27
Cutaneous myxosarcoma with pulmonary metastases in a dog. 61
21310431 2011
28
Multiple cerebral aneurysms and brain metastasis from primary cardiac myxosarcoma: a case report and literature review. 61
21733362 2011
29
Bilateral skin fold rotation-advancement flaps for the closure of large lumbosacral wounds in three dogs. 61
21495989 2011
30
Surgical treatment of cardiac myxosarcoma. 61
21484557 2011
31
Cardiac myxosarcoma with adrenal adenoma and pituitary hyperplasia resembling Carney complex in a dog. 61
20110224 2010
32
Primary myxosarcoma of the right inferior pulmonary vein presenting clinically as benign left atrial myxoma with a concurrent right lower lung tumor. 61
19139592 2009
33
What is your diagnosis? Vertebral mass in a dog. 61
19490569 2009
34
Use of destained cytology slides for the application of routine special stains. 61
19171014 2009
35
Endobronchial polyp derived from a myxosarcoma in the lung of a dog. 61
18981198 2008
36
What is your diagnosis? Muculent pleural effusion from a dog. 61
18761532 2008
37
Familial risk for soft tissue tumors: a nation-wide epidemiological study from Sweden. 61
17929055 2008
38
Imaging features of orbital myxosarcoma in dogs. 61
18546781 2008
39
The ataxia telangiectasia-mutated target site Ser18 is required for p53-mediated tumor suppression. 61
18089799 2007
40
Malignant tumours of the heart: a review of tumour type, diagnosis and therapy. 61
17693068 2007
41
Imaging diagnosis--spinal myxosarcoma in a dog. 61
18018729 2007
42
Odontogenic myxosarcoma of the jaw in a dog. 61
17993660 2007
43
Cutaneous neoplasms in pet rabbits: a retrospective study. 61
17846230 2007
44
Left atrium myxosarcoma: an exceptional cardiac malignant primary tumor. 61
17551954 2007
45
Left atrial myxosarcoma with previously detected intestinal metastasis. 61
17420810 2007
46
Carpal myxosarcoma and forelimb amputation in a ferret (Mustela putorius furo). 61
17142629 2006
47
Spontaneous subcutaneous myxosarcoma in a captive European hedgehog (Erinsceus europaeus). 61
17121099 2006
48
Intermandibular malignant mesenchymoma in a crossbreed dog. 61
16961475 2006
49
Second primary malignancies among patients with soft tissue tumors in Sweden. 61
16557572 2006
50
Measurement of tumor hypoxia in spontaneous canine sarcomas. 61
16229439 2005

Variations for Myxosarcoma

Expression for Myxosarcoma

Search GEO for disease gene expression data for Myxosarcoma.

Pathways for Myxosarcoma

GO Terms for Myxosarcoma

Cellular components related to Myxosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 8.8 PLPP3 PLPP1 PECAM1

Biological processes related to Myxosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phospholipid metabolic process GO:0006644 9.5 PLPP3 PLPP2 PLPP1
2 sphingolipid biosynthetic process GO:0030148 9.43 PLPP3 PLPP2 PLPP1
3 ceramide metabolic process GO:0006672 9.33 PLPP3 PLPP2 PLPP1
4 phospholipid dephosphorylation GO:0046839 9.13 PLPP3 PLPP2 PLPP1
5 sphingosine metabolic process GO:0006670 8.8 PLPP3 PLPP2 PLPP1

Molecular functions related to Myxosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phosphatase activity GO:0016791 9.43 PLPP3 PLPP2 PLPP1
2 lipid phosphatase activity GO:0042577 9.33 PLPP3 PLPP2 PLPP1
3 phosphatidate phosphatase activity GO:0008195 9.13 PLPP3 PLPP2 PLPP1
4 sphingosine-1-phosphate phosphatase activity GO:0042392 8.8 PLPP3 PLPP2 PLPP1

Sources for Myxosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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