Aliases & Classifications for Myxosarcoma

MalaCards integrated aliases for Myxosarcoma:

Name: Myxosarcoma 12 44 15 17 72

Classifications:



External Ids:

Disease Ontology 12 DOID:4136
MeSH 44 D009236
NCIt 50 C3255
SNOMED-CT 68 28351005
UMLS 72 C0027155

Summaries for Myxosarcoma

MalaCards based summary : Myxosarcoma is related to carney complex variant and pulmonary hypertension. An important gene associated with Myxosarcoma is MB (Myoglobin), and among its related pathways/superpathways is Factors involved in megakaryocyte development and platelet production. The drugs Parathyroid hormone and Fluorouracil have been mentioned in the context of this disorder. Affiliated tissues include heart, brain and lung.

Wikipedia : 75 Myxosarcoma is a rare malignant tumor of the... more...

Related Diseases for Myxosarcoma

Diseases related to Myxosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 carney complex variant 10.2
2 pulmonary hypertension 10.2
3 chondroma 10.2
4 congestive heart failure 10.2
5 posttransplant acute limbic encephalitis 10.2
6 intussusception 10.0
7 otitis media 10.0
8 chordoma 10.0
9 congenital heart defects, hamartomas of tongue, and polysyndactyly 10.0
10 yemenite deaf-blind hypopigmentation syndrome 10.0
11 hydrops, lactic acidosis, and sideroblastic anemia 10.0
12 fibroma 10.0
13 hemiplegia 10.0
14 pulmonary edema 10.0
15 diarrhea 10.0
16 pericarditis 10.0
17 mesenchymoma 10.0
18 bronchiolo-alveolar adenocarcinoma 10.0
19 heart sarcoma 10.0
20 adrenal adenoma 10.0
21 adenoma 10.0
22 hyperthyroidism 10.0
23 hard palate cancer 10.0
24 exophthalmos 10.0
25 intracranial hypertension 10.0
26 stomatitis 10.0
27 odontogenic myxoma 10.0
28 aneurysm 10.0
29 back pain 10.0
30 cerebral aneurysms 10.0
31 foot drop 10.0
32 syncope 10.0
33 rare tumor 10.0
34 intestinal polyposis syndrome 10.0
35 autosomal genetic disease 9.2 PRKAR1A HBD

Graphical network of the top 20 diseases related to Myxosarcoma:



Diseases related to Myxosarcoma

Symptoms & Phenotypes for Myxosarcoma

Drugs & Therapeutics for Myxosarcoma

Drugs for Myxosarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Parathyroid hormone Approved, Investigational Phase 1 9002-64-6
2
Fluorouracil Approved Phase 1 51-21-8 3385
3
Belinostat Approved, Investigational Phase 1 866323-14-0
4 Androgens Phase 1
5 Immunologic Factors Phase 1
6 Histone Deacetylase Inhibitors Phase 1
7 Immunosuppressive Agents Phase 1
8 Antimetabolites Phase 1
9 Antimetabolites, Antineoplastic Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase I Safety, Pharmacodynamic, Anti-Tumor Activity, and Pharmacokinetic Study of PXD101 Alone and in Combination With 5-Fluorouracil in Patients With Advanced Solid Tumors Completed NCT00413322 Phase 1 belinostat;5-Fluorouracil (5-FU)

Search NIH Clinical Center for Myxosarcoma

Cochrane evidence based reviews: myxosarcoma

Genetic Tests for Myxosarcoma

Anatomical Context for Myxosarcoma

MalaCards organs/tissues related to Myxosarcoma:

41
Heart, Brain, Lung, Breast, Skin, Bone, Spleen

Publications for Myxosarcoma

Articles related to Myxosarcoma:

(show top 50) (show all 155)
# Title Authors PMID Year
1
An extraskeletal osteosarcoma in the auricle of a Wistar Hannover rat. 38
31404367 2019
2
Canine myxosarcomas, a retrospective analysis of 32 dogs (2003-2018). 38
31248415 2019
3
TAENIA CRASSICEPS CYSTICERCOSIS IN A NILGIRI LANGUR ( SEMNOPITHECUS JOHNII). 38
29900783 2018
4
MHC-B haplotypes impact susceptibility and resistance to RSV-A infection. 38
29772523 2018
5
Extracardiac intrapericardial myxosarcoma causing right ventricular outflow tract obstruction in a dog. 38
29500126 2018
6
Retrobulbar malignant peripheral nerve sheath tumor in a golden retriever dog: A challenging diagnosis. 38
29606723 2018
7
Metastatic myxosarcoma in a Quarter Horse gelding. 38
28677418 2018
8
Charcot-Leyden crystals: do they exist in veterinary species? A case report and literature review. 38
28782436 2017
9
Clinical, computed tomographic, magnetic resonance imaging, and histologic findings associated with myxomatous neoplasia of the temporomandibular joint in two dogs. 38
27875090 2016
10
What Is Your Diagnosis? Myxosarcoma in a cat. 38
26331415 2015
11
Metronomic Chemotherapy for Myxosarcoma Treatment in a Kori Bustard (Ardeotis kori). 38
26378667 2015
12
Canine low-grade intra-orbital myxosarcoma: case report. 38
24837165 2015
13
Myxosarcoma of the maxilla - a case report. 38
25954712 2015
14
Multiple intra-abdominal serosal myxosarcomas in two koalas (Phascolarctos cinereus). 38
25728815 2015
15
Long-term survival after extended resection of primary atrial myxosarcoma. 38
25583907 2015
16
What is your diagnosis? Grade 2 myxosarcoma of the subcutis and bone. 38
25406700 2014
17
Axillary artery tumor embolism secondary to mitral valve myxosarcoma in a dog. 38
25471647 2014
18
Diagnosis and treatment of a periocular myxosarcoma in a bearded dragon (Pogona vitticeps). 38
24982518 2014
19
Cardiac myxosarcoma with thoracic spinal metastasis. 38
23677508 2014
20
One hundred two tumors in 100 goats (1987-2011). 38
23341420 2013
21
What is your diagnosis? Low-grade myxosarcoma arising from the heart valve. 38
23547667 2013
22
Intrathoracic myxosarcoma in a dog. 38
22520813 2012
23
Primary and metastatic cardiac sarcomas: a 12-year experience at a German heart center. 38
23119110 2012
24
Cutaneous myxosarcoma with pulmonary metastases in a dog. 38
21310431 2011
25
Multiple cerebral aneurysms and brain metastasis from primary cardiac myxosarcoma: a case report and literature review. 38
21733362 2011
26
Bilateral skin fold rotation-advancement flaps for the closure of large lumbosacral wounds in three dogs. 38
21495989 2011
27
Surgical treatment of cardiac myxosarcoma. 38
21484557 2011
28
Cardiac myxosarcoma with adrenal adenoma and pituitary hyperplasia resembling Carney complex in a dog. 38
20110224 2010
29
Primary myxosarcoma of the right inferior pulmonary vein presenting clinically as benign left atrial myxoma with a concurrent right lower lung tumor. 38
19139592 2009
30
What is your diagnosis? Vertebral mass in a dog. 38
19490569 2009
31
Use of destained cytology slides for the application of routine special stains. 38
19171014 2009
32
Endobronchial polyp derived from a myxosarcoma in the lung of a dog. 38
18981198 2008
33
What is your diagnosis? Muculent pleural effusion from a dog. 38
18761532 2008
34
Familial risk for soft tissue tumors: a nation-wide epidemiological study from Sweden. 38
17929055 2008
35
Imaging features of orbital myxosarcoma in dogs. 38
18546781 2008
36
The ataxia telangiectasia-mutated target site Ser18 is required for p53-mediated tumor suppression. 38
18089799 2007
37
Malignant tumours of the heart: a review of tumour type, diagnosis and therapy. 38
17693068 2007
38
Odontogenic myxosarcoma of the jaw in a dog. 38
17993660 2007
39
Imaging diagnosis--spinal myxosarcoma in a dog. 38
18018729 2007
40
Cutaneous neoplasms in pet rabbits: a retrospective study. 38
17846230 2007
41
Left atrium myxosarcoma: an exceptional cardiac malignant primary tumor. 38
17551954 2007
42
Left atrial myxosarcoma with previously detected intestinal metastasis. 38
17420810 2007
43
Carpal myxosarcoma and forelimb amputation in a ferret (Mustela putorius furo). 38
17142629 2006
44
Spontaneous subcutaneous myxosarcoma in a captive European hedgehog (Erinsceus europaeus). 38
17121099 2006
45
Intermandibular malignant mesenchymoma in a crossbreed dog. 38
16961475 2006
46
Second primary malignancies among patients with soft tissue tumors in Sweden. 38
16557572 2006
47
Measurement of tumor hypoxia in spontaneous canine sarcomas. 38
16229439 2005
48
Carcinosarcoma of the parotid gland: an unusual case with large-cell neuroendocrine carcinoma and rhabdomyosarcoma. 38
15996163 2005
49
[A rare cardiac tumor: the malignant fibrous histiocytoma. Description of a case]. 38
15554023 2004
50
Histopathological characteristics of spindle-cell proliferative disease in broiler chickens and its experimental reproduction in specific pathogen-free chickens. 38
15107549 2004

Variations for Myxosarcoma

Expression for Myxosarcoma

Search GEO for disease gene expression data for Myxosarcoma.

Pathways for Myxosarcoma

Pathways related to Myxosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.82 PRKAR1A HBD

GO Terms for Myxosarcoma

Biological processes related to Myxosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heart development GO:0007507 9.16 PRKAR1A MB
2 blood coagulation GO:0007596 8.96 PRKAR1A HBD
3 oxygen transport GO:0015671 8.62 MB HBD

Molecular functions related to Myxosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heme binding GO:0020037 9.16 MB HBD
2 oxygen binding GO:0019825 8.96 MB HBD
3 oxygen carrier activity GO:0005344 8.62 MB HBD

Sources for Myxosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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