MCID: NRC003
MIFTS: 27

Narcissistic Personality Disorder

Categories: Mental diseases

Aliases & Classifications for Narcissistic Personality Disorder

MalaCards integrated aliases for Narcissistic Personality Disorder:

Name: Narcissistic Personality Disorder 12 77 56 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:2745
ICD9CM 36 301.81
MeSH 45 D010554
NCIt 51 C92635
SNOMED-CT 69 80711002
ICD10 34 F60.81
UMLS 74 C0027402

Summaries for Narcissistic Personality Disorder

Disease Ontology : 12 A personality disorder that involves an excessive preoccupation with issues of personal adequacy, power, prestige and vanity.

MalaCards based summary : Narcissistic Personality Disorder is related to personality disorder and borderline personality disorder. An important gene associated with Narcissistic Personality Disorder is SMPD1 (Sphingomyelin Phosphodiesterase 1), and among its related pathways/superpathways are Human Thyroid Stimulating Hormone (TSH) signaling pathway and Transcription_Role of VDR in regulation of genes involved in osteoporosis. Affiliated tissues include brain.

Wikipedia : 77 Narcissistic personality disorder (NPD) is a personality disorder with a long-term pattern of abnormal... more...

Related Diseases for Narcissistic Personality Disorder

Diseases related to Narcissistic Personality Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 personality disorder 11.1
2 borderline personality disorder 10.3
3 disease of mental health 10.2
4 depression 10.2
5 histrionic personality disorder 10.0 OPRM1 PIR
6 attention deficit-hyperactivity disorder 10.0
7 frontotemporal dementia 10.0
8 bipolar disorder 10.0
9 pol iii-related leukodystrophies 10.0
10 dementia 10.0
11 mood disorder 10.0
12 separation anxiety disorder 10.0 OPRM1 PIR
13 ocular hypertension 9.8 CA2 JUN
14 dependent personality disorder 9.7 PIR SMPD1 WASF2

Comorbidity relations with Narcissistic Personality Disorder via Phenotypic Disease Network (PDN):


Anxiety Dependent Personality Disorder
Dysthymic Disorder Histrionic Personality Disorder
Hypertension, Essential Major Depressive Disorder

Graphical network of the top 20 diseases related to Narcissistic Personality Disorder:



Diseases related to Narcissistic Personality Disorder

Symptoms & Phenotypes for Narcissistic Personality Disorder

Drugs & Therapeutics for Narcissistic Personality Disorder

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Plasticity of the Compassionate Brain Completed NCT01833104 Not Applicable

Search NIH Clinical Center for Narcissistic Personality Disorder

Genetic Tests for Narcissistic Personality Disorder

Anatomical Context for Narcissistic Personality Disorder

MalaCards organs/tissues related to Narcissistic Personality Disorder:

42
Brain

Publications for Narcissistic Personality Disorder

Articles related to Narcissistic Personality Disorder:

(show top 50) (show all 131)
# Title Authors Year
1
Quasi-psychosis in covert Narcissistic Personality Disorder-A case report. ( 29272784 )
2018
2
Does Religiosity Reduce Narcissistic Personality Disorder? Examining the Case of Muslim University Students. ( 29691791 )
2018
3
Comparing self-report measures of grandiose narcissism, vulnerable narcissism, and narcissistic personality disorder in a male offender sample. ( 29792507 )
2018
4
Narcissist or narcissistic? Evaluation of the latent structure of narcissistic personality disorder. ( 30010367 )
2018
5
Symptom severity and mindreading in narcissistic personality disorder. ( 30110368 )
2018
6
A parallel process latent growth model of narcissistic personality disorder symptoms and normal personality traits. ( 30556721 )
2018
7
The role of shame and self-compassion in psychotherapy for narcissistic personality disorder: An exploratory study. ( 29265698 )
2017
8
Clinical Characteristics of Comorbid Narcissistic Personality Disorder in Patients With Borderline Personality Disorder. ( 28758884 )
2017
9
Countertransference when working with narcissistic personality disorder: An empirical investigation. ( 28581327 )
2017
10
Narcissistic Personality Disorder in Clinical Health Psychology Practice: Case Studies of Comorbid Psychological Distress and Life-Limiting Illness. ( 28767013 )
2017
11
Narcissistic Personality Disorder and suicidal behavior in mood disorders. ( 27816770 )
2017
12
Intersect between self-esteem and emotion regulation in narcissistic personality disorder - implications for alliance building and treatment. ( 28191317 )
2017
13
Clinician Ratings of Vulnerable and Grandiose Narcissistic Features: Implications for an Expanded Narcissistic Personality Disorder Diagnosis. ( 29215903 )
2017
14
Examining sex differences in DSM-IV-TR narcissistic personality disorder symptom expression using Item Response Theory (IRT). ( 29291575 )
2017
15
Demystifying Complexes, Transference, and Narcissistic Personality Disorder with Jung and Lacan. ( 27335529 )
2016
16
Borderline Personality Disorder and Narcissistic Personality Disorder Diagnoses From the Perspective of the DSM-5 Personality Traits: A Study on Italian Clinical Participants. ( 27660996 )
2016
17
Narcissistic personality disorder and suicide. ( 27658843 )
2016
18
Narcissistic Personality Disorder and the Structure of Common Mental Disorders. ( 27617650 )
2016
19
A systematic review on the relationship between antisocial, borderline and narcissistic personality disorder diagnostic traits and risk of violence to others in a clinical and forensic sample. ( 27777779 )
2016
20
A masked negative self-esteem? Implicit and explicit self-esteem in patients with Narcissistic Personality Disorder. ( 27254651 )
2016
21
Beauvoir and demystifying paradoxical characteristics of narcissistic personality disorder. ( 25969623 )
2015
22
Sex Bias in Classifying Borderline and Narcissistic Personality Disorder. ( 26421970 )
2015
23
Inpatient Therapeutic Assessment With Narcissistic Personality Disorder. ( 26408333 )
2015
24
Brain structure in narcissistic personality disorder: a VBM and DTI pilot study. ( 25492857 )
2015
25
Narcissistic personality disorder: diagnostic and clinical challenges. ( 25930131 )
2015
26
Ruminations on narcissistic personality disorder. ( 24796569 )
2014
27
The narcissism epidemic: commentary on modernity and narcissistic personality disorder. ( 24796568 )
2014
28
Moving the field forward: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314233 )
2014
29
Response to commentaries: modernity and narcissistic personality disorder. ( 24796571 )
2014
30
Empathy in narcissistic personality disorder: from clinical and empirical perspectives. ( 24512457 )
2014
31
Phenomenology in need of treatment: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314234 )
2014
32
Stability of narcissistic personality disorder: tracking categorical and dimensional rating systems over a two-year period. ( 24512458 )
2014
33
Narcissistic personality disorder: an integrative review of recent empirical data and current definitions. ( 24633939 )
2014
34
Beyond the diagnostic traits: A collaborative exploratory diagnostic process for dimensions and underpinnings of narcissistic personality disorder. ( 25314232 )
2014
35
Narcissistic personality disorder and becoming old. ( 24399659 )
2014
36
Introduction to the special series on "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314230 )
2014
37
A Fairbairnian structural analysis of the narcissistic personality disorder. ( 24866161 )
2014
38
Vulnerable narcissism: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314236 )
2014
39
The maturation of narcissism: Commentary for the special series "Narcissistic personality disorder-New perspectives on diagnosis and treatment". ( 25314235 )
2014
40
A comparison of the criterion validity of popular measures of narcissism and narcissistic personality disorder via the use of expert ratings. ( 24773036 )
2014
41
How to spot a narcissist: Mental health literacy with respect to Narcissistic Personality Disorder. ( 25279811 )
2014
42
Borderline personality disorder, bipolar disorder, depression, attention deficit/hyperactivity disorder, and narcissistic personality disorder: Practical differential diagnosis. ( 23428169 )
2013
43
The Narcissistic Personality Inventory: a useful tool for assessing pathological narcissism? Evidence from patients with Narcissistic Personality Disorder. ( 23101721 )
2013
44
Gray matter abnormalities in patients with narcissistic personality disorder. ( 23777939 )
2013
45
Fear and decision-making in narcissistic personality disorder-a link between psychoanalysis and neuroscience. ( 24174893 )
2013
46
Attachment and object relations in patients with narcissistic personality disorder: implications for therapeutic process and outcome. ( 23996275 )
2013
47
An update on narcissistic personality disorder. ( 23187086 )
2013
48
The validity of the Personality Diagnostic Questionnaire-4 Narcissistic Personality Disorder scale for assessing pathological grandiosity. ( 23101760 )
2013
49
Shame in patients with narcissistic personality disorder. ( 24321228 )
2013
50
Narcissistic Personality Disorder in DSM-5. ( 23834518 )
2013

Variations for Narcissistic Personality Disorder

Expression for Narcissistic Personality Disorder

Search GEO for disease gene expression data for Narcissistic Personality Disorder.

Pathways for Narcissistic Personality Disorder

Pathways related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.96 CGA JUN TTF2
2 10.45 CA2 CGA JUN

GO Terms for Narcissistic Personality Disorder

Biological processes related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to hydrogen peroxide GO:0042542 9.37 FKBP1B JUN
2 cellular response to hormone stimulus GO:0032870 9.32 CGA JUN
3 response to cocaine GO:0042220 9.26 OPRM1 SMPD1
4 response to radiation GO:0009314 9.16 JUN OPRM1
5 monocyte differentiation GO:0030224 8.96 JUN PIR
6 response to organic substance GO:0010033 8.8 CA2 FKBP1B JUN

Molecular functions related to Narcissistic Personality Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.32 BAZ2B CA2 CGA FKBP1B JUN OPRM1

Sources for Narcissistic Personality Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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