MCID: NSL003
MIFTS: 32

Nasal Cavity Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Nasal Cavity Adenocarcinoma

MalaCards integrated aliases for Nasal Cavity Adenocarcinoma:

Name: Nasal Cavity Adenocarcinoma 12 15
Adenocarcinoma of Nasal Cavity 12 70
Adenocarcinoma of the Nasal Cavity 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4930
NCIt 50 C6015
UMLS 70 C1334920

Summaries for Nasal Cavity Adenocarcinoma

Disease Ontology : 12 A nasal cavity carcinoma that derives from epithelial cells of glandular origin.

MalaCards based summary : Nasal Cavity Adenocarcinoma, also known as adenocarcinoma of nasal cavity, is related to adenocarcinoma and mucoepidermoid carcinoma, and has symptoms including pain and rhinorrhea. An important gene associated with Nasal Cavity Adenocarcinoma is CXCL11 (C-X-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Gastric cancer and Human T-cell leukemia virus 1 infection. Affiliated tissues include lung, skin and colon, and related phenotypes are homeostasis/metabolism and digestive/alimentary

Related Diseases for Nasal Cavity Adenocarcinoma

Diseases related to Nasal Cavity Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 406)
# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 30.1 TP53 KRT7 KRAS HRAS CDX2 CDKN2A
2 mucoepidermoid carcinoma 30.1 TP53 KRT7 CDKN2A CALCA
3 mucinous adenocarcinoma 30.0 TP53 KRT7 KRAS CDX2 CDKN2A
4 appendix adenocarcinoma 30.0 SYP KRT7 KRAS HRAS CDX2
5 colorectal adenocarcinoma 29.9 TP53 KRT7 KRAS HRAS CDX2 CDKN2A
6 adenoid cystic carcinoma 29.3 TP53 SOX10 NFIB KRT7 KRAS HRAS
7 hepatic flexure cancer 10.4 KRAS HRAS
8 ethmoid sinus cancer 10.4 HRAS CDX2
9 signet ring basal cell carcinoma 10.4 KRAS HRAS
10 cobblestone retinal degeneration 10.4 KRAS HRAS
11 gastric signet ring cell adenocarcinoma 10.4 KRT7 CDX2
12 anal gland adenocarcinoma 10.4 KRT7 CDX2
13 ureter adenocarcinoma 10.4 KRT7 CDX2
14 anus adenocarcinoma 10.4 KRT7 CDX2
15 immature teratoma of ovary 10.4 KRAS HRAS
16 adenosquamous colon carcinoma 10.4 KRT7 CDX2
17 bartholin's gland disease 10.4 KRT7 CDX2
18 urinary bladder villous adenoma 10.4 KRT7 CDX2
19 bartholin's gland carcinoma 10.4 KRT7 CDX2
20 vulva adenocarcinoma 10.4 KRT7 CDX2
21 female urethral cancer 10.4 KRT7 CDX2
22 cystitis cystica 10.4 KRT7 CDX2
23 mucinous intrahepatic cholangiocarcinoma 10.4 KRT7 CDX2
24 periampullary adenoma 10.4 KRAS HRAS
25 rectosigmoid junction neoplasm 10.4 KRT7 KRAS
26 acneiform dermatitis 10.4 KRAS HRAS
27 jejunal cancer 10.4 KRT7 CDX2
28 adenosquamous lung carcinoma 10.4 KRAS HRAS
29 cervical basaloid squamous cell carcinoma 10.4 KRT7 CDKN2A
30 anal canal adenocarcinoma 10.4 KRT7 CDX2
31 mucinous lung adenocarcinoma 10.4 KRAS HRAS
32 mucinous bronchioloalveolar adenocarcinoma 10.4 KRT7 CDX2
33 inverted transitional papilloma 10.4 KRT7 CDKN2A
34 jejunal adenocarcinoma 10.4 KRT7 CDX2
35 breast hemangioma 10.3 TP53 KRT7
36 atrophic vulva 10.3 KRT7 CDKN2A
37 necrotizing sialometaplasia 10.3 TP53 KRT7
38 descending colon cancer 10.3 KRAS HRAS CDX2
39 intratubular embryonal carcinoma 10.3 TP53 KRT7
40 lung adenoid cystic carcinoma 10.3 NFIB KRT7
41 ascending colon cancer 10.3 KRAS HRAS CDX2
42 postcholecystectomy syndrome 10.3 GAST CCK
43 transverse colon cancer 10.3 KRT7 KRAS HRAS
44 maxillary sinus adenocarcinoma 10.3 TP53 CXCL11
45 gallbladder benign neoplasm 10.3 KRT7 KRAS HRAS
46 gastric diffuse adenocarcinoma 10.3 KRT7 CDX2
47 wolffian duct adenocarcinoma 10.3 KRT7 KRAS HRAS
48 papillary transitional carcinoma 10.3 TP53 KRT7
49 external ear carcinoma 10.3 KRT7 CALCA
50 sigmoid neoplasm 10.3 KRT7 KRAS CDX2

Graphical network of the top 20 diseases related to Nasal Cavity Adenocarcinoma:



Diseases related to Nasal Cavity Adenocarcinoma

Symptoms & Phenotypes for Nasal Cavity Adenocarcinoma

UMLS symptoms related to Nasal Cavity Adenocarcinoma:


pain; rhinorrhea

MGI Mouse Phenotypes related to Nasal Cavity Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.21 ANO1 ANXA1 CCK CDKN2A CDX2 GAST
2 digestive/alimentary MP:0005381 10.17 ANO1 ANXA1 CDKN2A CDX2 GAST HRAS
3 endocrine/exocrine gland MP:0005379 10.14 ANXA1 CCK CDKN2A CDX2 GAST HRAS
4 integument MP:0010771 9.97 ANO1 CDKN2A HRAS KRAS MLANA PDYN
5 nervous system MP:0003631 9.93 ANO1 ANXA1 CCK CDKN2A HRAS KRAS
6 neoplasm MP:0002006 9.91 ANXA1 CDKN2A CDX2 GAST HRAS KRAS
7 no phenotypic analysis MP:0003012 9.61 CCK CDKN2A HRAS KRAS MLANA PDYN
8 pigmentation MP:0001186 9.1 CDKN2A KRAS MLANA POMC SOX10 TP53

Drugs & Therapeutics for Nasal Cavity Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Nasal Cavity Adenocarcinoma

Genetic Tests for Nasal Cavity Adenocarcinoma

Anatomical Context for Nasal Cavity Adenocarcinoma

MalaCards organs/tissues related to Nasal Cavity Adenocarcinoma:

40
Lung, Skin, Colon, Thyroid, Ovary, Breast, Bone

Publications for Nasal Cavity Adenocarcinoma

Articles related to Nasal Cavity Adenocarcinoma:

# Title Authors PMID Year
1
Intestinal and non-intestinal nasal cavity adenocarcinoma: Impact of wood dust exposure. 61
30201443 2018
2
[Low-grade adenocarcinoma of nasal cavities: a case report]. 61
25284635 2014
3
[Adenocarcinomas of nasal cavities and paranasal sinuses: Diagnostic pitfalls in sinonasal glandular lesions]. 61
19900634 2009
4
Low-grade adenocarcinoma of the nasal cavity--an unusual presentation: case report and review of the literature. 61
17385618 2007

Variations for Nasal Cavity Adenocarcinoma

Expression for Nasal Cavity Adenocarcinoma

Search GEO for disease gene expression data for Nasal Cavity Adenocarcinoma.

Pathways for Nasal Cavity Adenocarcinoma

GO Terms for Nasal Cavity Adenocarcinoma

Cellular components related to Nasal Cavity Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 terminal bouton GO:0043195 8.8 SYP CCK CALCA

Biological processes related to Nasal Cavity Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.72 TP53 SOX10 KRAS HRAS CDKN2A
2 G protein-coupled receptor signaling pathway GO:0007186 9.7 POMC PDYN GAST CXCL11 CCK CALCA
3 response to isolation stress GO:0035900 9.26 KRAS HRAS
4 regulation of long-term neuronal synaptic plasticity GO:0048169 9.13 SYP KRAS HRAS
5 Ras protein signal transduction GO:0007265 8.92 TP53 KRAS HRAS CDKN2A

Molecular functions related to Nasal Cavity Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding GO:0001216 9.16 TP53 SOX10
2 MDM2/MDM4 family protein binding GO:0097371 8.96 TP53 CDKN2A
3 hormone activity GO:0005179 8.92 POMC GAST CCK CALCA

Sources for Nasal Cavity Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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