MCID: NSL010
MIFTS: 32

Nasal Cavity Neoplasm

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Nasal Cavity Neoplasm

MalaCards integrated aliases for Nasal Cavity Neoplasm:

Name: Nasal Cavity Neoplasm 12 15
Tumor of the Nasal Cavity 12
Neoplasm of Nasal Cavity 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9310
NCIt 51 C4413
UMLS 74 C0345630

Summaries for Nasal Cavity Neoplasm

MalaCards based summary : Nasal Cavity Neoplasm, also known as tumor of the nasal cavity, is related to nasal cavity cancer and hemangiopericytoma, malignant. An important gene associated with Nasal Cavity Neoplasm is AVP (Arginine Vasopressin), and among its related pathways/superpathways are Degradation of the extracellular matrix and Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways. The drugs Cisplatin and Etoposide have been mentioned in the context of this disorder.

Related Diseases for Nasal Cavity Neoplasm

Diseases related to Nasal Cavity Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 nasal cavity cancer 11.3
2 hemangiopericytoma, malignant 10.4
3 olfactory neuroblastoma 10.3
4 middle ear carcinoma 10.3
5 kaposiform hemangioendothelioma 10.1 CD34 PECAM1
6 erythema elevatum diutinum 10.1 CD34 PECAM1
7 extracranial arteriovenous malformation 10.1 MMP2 MMP9
8 inflammatory myofibroblastic tumor 10.1
9 focal myositis 10.1 MMP2 MMP9
10 villous adenocarcinoma 10.1 MMP2 MMP9
11 spastic entropion 10.1 MMP2 MMP9
12 lentigo maligna melanoma 10.1 MMP2 MMP9
13 acute transverse myelitis 10.1 MMP2 MMP9
14 transverse myelitis 10.1 MMP2 MMP9
15 senile ectropion 10.1 MMP2 MMP9
16 ischemic colitis 10.1 MMP2 MMP9
17 light chain deposition disease 10.1 MMP2 MMP9
18 conjunctival nevus 10.1 MMP2 MMP9
19 parotitis 10.1 MMP2 MMP9
20 klatskin's tumor 10.1 MMP2 MMP9
21 middle ear squamous cell carcinoma 10.1 CD34 MMP9
22 corneal ulcer 10.1 MMP2 MMP9
23 nasal cavity squamous cell carcinoma 10.1 MMP2 MMP9
24 odontogenic myxoma 10.1 MMP2 MMP9
25 newcastle disease 10.1 MMP2 MMP9
26 laryngeal disease 10.1 MMP2 MMP9
27 hypertensive heart disease 10.1 MMP2 MMP9
28 pneumothorax 10.1 MMP2 MMP9
29 aortic aneurysm, familial abdominal, 1 10.1 MMP2 MMP9
30 adenomyosis 10.0 MMP2 MMP9
31 fibroma 10.0
32 giant cell tumor 10.0
33 glomus tumor 10.0
34 neurofibroma 10.0
35 grade iii astrocytoma 10.0 MMP2 MMP9
36 skin melanoma 10.0 MMP2 MMP9
37 aortic disease 10.0 MMP2 MMP9
38 varicose veins 10.0 MMP2 MMP9
39 inguinal hernia 10.0 MMP2 MMP9
40 tongue cancer 10.0 MMP2 MMP9
41 oral cancer 10.0 MMP2 MMP9
42 female reproductive system disease 9.9 MMP2 MMP9
43 reproductive system disease 9.9 MMP2 MMP9
44 chondrosarcoma 9.9
45 osteoblastoma 9.9
46 fibrous dysplasia 9.9
47 ossifying fibroma 9.9
48 chondroma 9.9
49 perivascular epithelioid cell tumor 9.9
50 fibrosarcoma 9.9

Graphical network of the top 20 diseases related to Nasal Cavity Neoplasm:



Diseases related to Nasal Cavity Neoplasm

Symptoms & Phenotypes for Nasal Cavity Neoplasm

Drugs & Therapeutics for Nasal Cavity Neoplasm

Drugs for Nasal Cavity Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 11)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 2 15663-27-1 441203 84093 2767
2
Etoposide Approved Phase 2 33419-42-0 36462
3
Ipilimumab Approved Phase 2 477202-00-9
4
nivolumab Approved Phase 2 946414-94-4
5 Etoposide phosphate Phase 2
6 Topoisomerase Inhibitors Phase 2
7 Antineoplastic Agents, Phytogenic Phase 2
8 Antibodies Phase 2
9 Antibodies, Monoclonal Phase 2
10 Antineoplastic Agents, Immunological Phase 2
11 Immunoglobulins Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages Recruiting NCT03274414 Phase 2 Cisplatin;cisplatin and etoposide
2 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2

Search NIH Clinical Center for Nasal Cavity Neoplasm

Genetic Tests for Nasal Cavity Neoplasm

Anatomical Context for Nasal Cavity Neoplasm

Publications for Nasal Cavity Neoplasm

Articles related to Nasal Cavity Neoplasm:

(show all 29)
# Title Authors Year
1
Malignant peripheral nerve sheath tumor of the nasal cavity and nasopharynx in a child: A case report. ( 30681599 )
2019
2
Phosphaturic mesenchymal tumor of the nasal cavity and paranasal sinuses: A clinical curiosity presenting a diagnostic challenge. ( 28579442 )
2018
3
Haemangiopericytoma-like tumor of the nasal cavity treated by endoscopy - a case report. ( 27760096 )
2016
4
Inflammatory Myofibroblastic Tumor of the Nasal Cavity. ( 26483083 )
2015
5
Solitary fibrous tumor of the nasal cavity and paranasal sinuses: A case report. ( 26258025 )
2015
6
Hemangiopericytoma like tumor of the nasal cavity: a case report. ( 22339571 )
2012
7
Hybrid peripheral nerve sheath tumor of the nasal cavity showing schwannomatous, neurofibromatous, and perineuriomatous areas. ( 20683694 )
2010
8
Inaccurate summary of peripheral nerve sheath tumors in extradigital sites. Comment on "Hybrid peripheral nerve sheath tumor of the nasal cavity showing schwannomatous, neurofibromatus, and perineuriomatous areas. Med Mol Morphol (2010) 43:82-85". ( 21267704 )
2010
9
Perivascular epithelioid cell tumor of the nasal cavity with TFE3 expression. ( 19788626 )
2009
10
Solitary fibrous tumor of the nasal cavity. ( 19893953 )
2009
11
Pathology case quiz 2. Solitary fibrous tumor of the nasal cavity and ethmoid sinus with intracranial extension. ( 18347266 )
2008
12
Inflammatory myofibroblastic tumor of the nasal cavity. ( 17213441 )
2007
13
Giant cell tumor of the nasal cavity: case report. ( 16977452 )
2007
14
Malignant solitary fibrous tumor of the nasal cavity. ( 18174924 )
2007
15
Typical carcinoid tumor of the nasal cavity. ( 17481837 )
2007
16
Solitary fibrous tumor of the nasal cavity and paranasal sinuses. ( 17141102 )
2006
17
Malignant mixed tumor of the nasal cavity. ( 16188415 )
2006
18
Invasive glomus tumor of the nasal cavity. ( 15858779 )
2005
19
The role of intensity modulated radiation therapy for favorable stage tumor of the nasal cavity or ethmoid sinus. ( 16199987 )
2005
20
A rare case of solitary fibrous tumor of the nasal cavity. ( 12927298 )
2003
21
Malignant triton tumor of the nasal cavity. ( 11774393 )
2001
22
Inflammatory myofibroblastic tumor of the nasal cavity: a case report and review of the literature. ( 11589984 )
2001
23
Pyogenic granuloma (pregnancy tumor) of the nasal cavity. A case report. ( 11027085 )
2000
24
Solitary fibrous tumor of the nasal cavity. ( 10580246 )
1999
25
Solitary fibrous tumor of the nasal cavity and orbit. ( 8808301 )
1995
26
Solitary fibrous tumor of the nasal cavity and paranasal sinuses. ( 1989459 )
1991
27
An unusual embryonal tumor of the nasal cavity in a neonate--a nasal blastoma? A clinical, histologic, and ultrastructural study. ( 2555819 )
1989
28
Hemangiopericytoma-like tumor of the nasal cavity. Report of a case and review of the literature. ( 7469906 )
1981
29
Glomus tumor of the nasal cavity. ( 4302687 )
1968

Variations for Nasal Cavity Neoplasm

Expression for Nasal Cavity Neoplasm

Search GEO for disease gene expression data for Nasal Cavity Neoplasm.

Pathways for Nasal Cavity Neoplasm

Pathways related to Nasal Cavity Neoplasm according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.39 MMP2 MMP9 PECAM1
2
Show member pathways
12.22 MMP2 MMP9 PECAM1
3 11.46 MMP2 MMP9
4 11.41 MMP2 MMP9
5 11.36 MMP2 MMP9
6 11.34 MMP2 MMP9
7 11.31 MMP2 MMP9
8
Show member pathways
11.29 MMP2 MMP9
9 11.27 MMP2 MMP9 PECAM1
10 11.26 MMP2 MMP9
11 11.11 MMP2 MMP9
12
Show member pathways
11.06 MMP2 MMP9
13 10.9 MMP2 MMP9
14 10.83 MMP2 MMP9
15 10.75 MMP2 MMP9 PECAM1
16 10.67 MMP2 MMP9
17 10.52 MMP2 MMP9

GO Terms for Nasal Cavity Neoplasm

Cellular components related to Nasal Cavity Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 CD34 PECAM1

Biological processes related to Nasal Cavity Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ephrin receptor signaling pathway GO:0048013 9.43 MMP2 MMP9
2 extracellular matrix disassembly GO:0022617 9.4 MMP2 MMP9
3 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.37 MMP2 MMP9
4 embryo implantation GO:0007566 9.32 MMP2 MMP9
5 collagen catabolic process GO:0030574 9.26 MMP2 MMP9
6 endodermal cell differentiation GO:0035987 9.16 MMP2 MMP9
7 leukocyte migration GO:0050900 9.13 CD34 MMP9 PECAM1
8 glomerular endothelium development GO:0072011 8.62 CD34 PECAM1

Sources for Nasal Cavity Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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