MCID: NSL005
MIFTS: 27

Nasal Cavity Olfactory Neuroblastoma

Categories: Cancer diseases, Neuronal diseases, Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Nasal Cavity Olfactory Neuroblastoma

MalaCards integrated aliases for Nasal Cavity Olfactory Neuroblastoma:

Name: Nasal Cavity Olfactory Neuroblastoma 12 15 71
Olfactory Neuroblastoma of the Nasal Cavity 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10812
NCIt 49 C7604
UMLS 71 C1334923

Summaries for Nasal Cavity Olfactory Neuroblastoma

MalaCards based summary : Nasal Cavity Olfactory Neuroblastoma, also known as olfactory neuroblastoma of the nasal cavity, is related to olfactory neuroblastoma and primary congenital hypothyroidism. An important gene associated with Nasal Cavity Olfactory Neuroblastoma is PTN (Pleiotrophin), and among its related pathways/superpathways are Neuroscience and Hematopoietic Stem Cells and Lineage-specific Markers. Affiliated tissues include pituitary, and related phenotypes are cellular and nervous system

Related Diseases for Nasal Cavity Olfactory Neuroblastoma

Diseases related to Nasal Cavity Olfactory Neuroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 495)
# Related Disease Score Top Affiliating Genes
1 olfactory neuroblastoma 30.6 SYP NKX2-1 ENO2
2 primary congenital hypothyroidism 10.5 PAX8 NKX2-1
3 combined thymoma 10.5 PAX8 KRT5
4 thyroid malformation 10.5 PAX8 NKX2-1
5 apocrine adenocarcinoma 10.5 KRT7 KRT5
6 ureterocele 10.4 PAX8 PAX2
7 anal canal paget's disease 10.4 KRT7 CDX2
8 anal gland adenocarcinoma 10.4 KRT7 CDX2
9 clear cell adenoma 10.4 TG PAX8
10 gastric signet ring cell adenocarcinoma 10.4 KRT7 CDX2
11 adenosquamous colon carcinoma 10.4 KRT7 CDX2
12 nasal cavity adenocarcinoma 10.4 KRT7 CDX2
13 anus adenocarcinoma 10.4 KRT7 CDX2
14 ureter squamous cell carcinoma 10.4 KRT7 KRT5
15 bartholin's gland carcinoma 10.4 KRT7 CDX2
16 benign struma ovarii 10.4 TG KRT19
17 inverted transitional papilloma 10.4 KRT7 KRT5
18 bartholin's gland disease 10.4 KRT7 CDX2
19 ceruminoma 10.4 KRT7 KRT5
20 proliferating trichilemmal cyst 10.4 KRT7 KRT19
21 jejunal cancer 10.4 KRT7 CDX2
22 microinvasive cervical squamous cell carcinoma 10.4 KRT7 KRT5
23 jejunal adenocarcinoma 10.4 KRT7 CDX2
24 benign breast adenomyoepithelioma 10.4 KRT7 KRT5
25 urethral diverticulum 10.4 PAX8 KRT7
26 ovarian primitive germ cell tumor 10.4 KRT7 CDX2
27 ceruminous adenocarcinoma 10.4 KRT7 KRT5
28 odontoma 10.4 KRT5 KRT19
29 intrahepatic bile duct adenoma 10.4 KRT7 KRT19
30 lung clear cell carcinoma 10.4 KRT7 KRT5
31 gastric squamous cell carcinoma 10.4 KRT7 KRT5
32 necrotizing sialometaplasia 10.4 KRT7 KRT5
33 cloacogenic carcinoma 10.4 KRT5 ENO2
34 glandular cystitis 10.3 KRT7 CDX2
35 lung meningioma 10.3 SYP NKX2-1
36 breast mucinous carcinoma 10.3 KRT7 KRT5
37 pericardial mesothelioma 10.3 KRT5 KRT19
38 intrahepatic gall duct cancer 10.3 KRT7 KRT19
39 malignant biphasic mesothelioma 10.3 KRT7 KRT5
40 lipoadenoma 10.3 KRT7 KRT19
41 large cell acanthoma 10.3 KRT7 KRT5
42 cervix endometriosis 10.3 PAX2 MME
43 thymus basaloid carcinoma 10.3 PAX8 NKX2-1 KRT5
44 laryngeal mucoepidermoid carcinoma 10.3 CEACAM5 CDX2
45 classic pulmonary blastoma 10.3 NKX2-1 CEACAM5
46 nephrogenic adenoma 10.3 PAX8 PAX2 KRT7
47 larynx sarcoma 10.3 NKX2-1 CEACAM5
48 clear cell adenocarcinoma 10.3 PAX8 PAX2 KRT7
49 breast papillary carcinoma 10.3 SYP KRT5
50 bladder benign neoplasm 10.3 PAX8 PAX2 KRT7

Graphical network of the top 20 diseases related to Nasal Cavity Olfactory Neuroblastoma:



Diseases related to Nasal Cavity Olfactory Neuroblastoma

Symptoms & Phenotypes for Nasal Cavity Olfactory Neuroblastoma

MGI Mouse Phenotypes related to Nasal Cavity Olfactory Neuroblastoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.65 CDX2 ENO2 KRT19 KRT7 MME NCAM1
2 nervous system MP:0003631 9.32 ENO2 KRT19 MME NCAM1 NKX2-1 PAX2

Drugs & Therapeutics for Nasal Cavity Olfactory Neuroblastoma

Search Clinical Trials , NIH Clinical Center for Nasal Cavity Olfactory Neuroblastoma

Genetic Tests for Nasal Cavity Olfactory Neuroblastoma

Anatomical Context for Nasal Cavity Olfactory Neuroblastoma

MalaCards organs/tissues related to Nasal Cavity Olfactory Neuroblastoma:

40
Pituitary

Publications for Nasal Cavity Olfactory Neuroblastoma

Articles related to Nasal Cavity Olfactory Neuroblastoma:

# Title Authors PMID Year
1
A Unilateral Nasal Mass With Generalized Seizures: Potential Diagnostic Pitfalls in Giant Pituitary Adenoma. 61
31897352 2019
2
[Extensive olfactory neuroblastoma of the nasal cavity and paranasal sinuses]. 61
20684358 2010
3
[Olfactory neuroblastoma of the nasal cavity (author's transl)]. 61
7341184 1981
4
Olfactory neuroblastoma (esthesioneuroblastoma): a light and ultrastructural study of two cases. 61
383258 1979

Variations for Nasal Cavity Olfactory Neuroblastoma

Expression for Nasal Cavity Olfactory Neuroblastoma

Search GEO for disease gene expression data for Nasal Cavity Olfactory Neuroblastoma.

Pathways for Nasal Cavity Olfactory Neuroblastoma

Pathways related to Nasal Cavity Olfactory Neuroblastoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.89 SYP NKX2-1 NCAM1 ENO2 CALCA
2 11.56 NCAM1 MME CEACAM5
3
Show member pathways
11.47 KRT7 KRT5 KRT19
4 11.23 SYP PAX2 NCAM1
5 11.05 PAX2 NCAM1 KRT19 CDX2
6 10.57 PAX8 PAX2

GO Terms for Nasal Cavity Olfactory Neuroblastoma

Biological processes related to Nasal Cavity Olfactory Neuroblastoma according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.74 KRT7 KRT5 KRT19
2 lung development GO:0030324 9.72 PTN NKX2-1 MME
3 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.58 PAX8 PAX2
4 urogenital system development GO:0001655 9.58 PAX8 PAX2
5 mesonephros development GO:0001823 9.56 PAX8 PAX2
6 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.54 PAX8 PAX2
7 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.52 PAX8 PAX2
8 pronephros development GO:0048793 9.51 PAX8 PAX2
9 metanephric epithelium development GO:0072207 9.49 PAX8 PAX2
10 metanephric nephron tubule formation GO:0072289 9.48 PAX8 PAX2
11 metanephric distal convoluted tubule development GO:0072221 9.46 PAX8 PAX2
12 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.43 PAX8 PAX2
13 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.4 PAX8 PAX2
14 positive regulation of metanephric DCT cell differentiation GO:2000594 9.37 PAX8 PAX2
15 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.32 PAX8 PAX2
16 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.26 PAX8 PAX2
17 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.16 PAX8 PAX2
18 pronephric field specification GO:0039003 8.96 PAX8 PAX2
19 thyroid gland development GO:0030878 8.8 TG PAX8 NKX2-1

Sources for Nasal Cavity Olfactory Neuroblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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