MCID: NSL005
MIFTS: 27

Nasal Cavity Olfactory Neuroblastoma

Categories: Cancer diseases, Neuronal diseases, Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Nasal Cavity Olfactory Neuroblastoma

MalaCards integrated aliases for Nasal Cavity Olfactory Neuroblastoma:

Name: Nasal Cavity Olfactory Neuroblastoma 12 15 71
Olfactory Neuroblastoma of the Nasal Cavity 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10812
NCIt 49 C7604
UMLS 71 C1334923

Summaries for Nasal Cavity Olfactory Neuroblastoma

MalaCards based summary : Nasal Cavity Olfactory Neuroblastoma, also known as olfactory neuroblastoma of the nasal cavity, is related to olfactory neuroblastoma and urethra adenocarcinoma. An important gene associated with Nasal Cavity Olfactory Neuroblastoma is PTN (Pleiotrophin), and among its related pathways/superpathways are Neuroscience and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Related phenotypes are cellular and nervous system

Related Diseases for Nasal Cavity Olfactory Neuroblastoma

Diseases related to Nasal Cavity Olfactory Neuroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 477)
# Related Disease Score Top Affiliating Genes
1 olfactory neuroblastoma 30.6 SYP NKX2-1 ENO2
2 urethra adenocarcinoma 10.6 PAX8 PAX2
3 urethra cancer 10.5 PAX8 PAX2
4 primary congenital hypothyroidism 10.5 PAX8 NKX2-1
5 apocrine adenocarcinoma 10.5 KRT7 KRT5
6 thyroid malformation 10.5 PAX8 NKX2-1
7 ovarian mesodermal adenosarcoma 10.5 PAX8 KRT7
8 bladder signet ring cell adenocarcinoma 10.5 KRT7 CDX2
9 ureterocele 10.5 PAX8 PAX2
10 anal canal paget's disease 10.5 KRT7 CDX2
11 gastric signet ring cell adenocarcinoma 10.5 KRT7 CDX2
12 adenosquamous colon carcinoma 10.5 KRT7 CDX2
13 nasal cavity adenocarcinoma 10.5 KRT7 CDX2
14 anus adenocarcinoma 10.5 KRT7 CDX2
15 inverted transitional papilloma 10.4 KRT7 KRT5
16 cystitis cystica 10.4 KRT7 CDX2
17 ceruminoma 10.4 KRT7 KRT5
18 benign breast adenomyoepithelioma 10.4 KRT7 KRT5
19 breast adenomyoepithelioma 10.4 KRT7 KRT5
20 urethral diverticulum 10.4 PAX8 KRT7
21 bone leiomyosarcoma 10.4 KRT7 KRT5
22 proliferating trichilemmal cyst 10.4 KRT7 KRT19
23 microinvasive cervical squamous cell carcinoma 10.4 KRT7 KRT5
24 intrahepatic bile duct adenoma 10.4 KRT7 KRT19
25 breast hemangiopericytoma 10.4 KRT7 KRT19
26 solid adenocarcinoma with mucin production 10.4 NKX2-1 KRT7
27 jejunal cancer 10.4 KRT7 CDX2
28 ceruminous adenocarcinoma 10.4 KRT7 KRT5
29 combined thymoma 10.4 PAX8 KRT5
30 atypical follicular adenoma 10.4 TG PAX8
31 gastric squamous cell carcinoma 10.4 KRT7 KRT5
32 odontoma 10.4 KRT5 KRT19
33 breast myoepithelial neoplasm 10.4 KRT7 KRT5
34 necrotizing sialometaplasia 10.4 KRT7 KRT5
35 pericardial mesothelioma 10.4 KRT5 KRT19
36 breast metaplastic carcinoma 10.4 KRT7 KRT5
37 mucinous stomach adenocarcinoma 10.4 KRT7 CDX2
38 breast mucinous carcinoma 10.4 KRT7 KRT5
39 metatypical basal cell carcinoma 10.4 KRT7 KRT5
40 lipoadenoma 10.4 KRT7 KRT19
41 tumor of exocrine pancreas 10.4 KRT7 CDX2
42 intrahepatic gall duct cancer 10.4 KRT7 KRT19
43 large cell acanthoma 10.4 KRT7 KRT5
44 lung meningioma 10.4 SYP NKX2-1
45 cervix endometriosis 10.3 PAX2 MME
46 nephrogenic adenoma 10.3 PAX8 PAX2 KRT7
47 ovarian cystic teratoma 10.3 SYP NKX2-1
48 clear cell adenocarcinoma 10.3 PAX8 PAX2 KRT7
49 lung acinar adenocarcinoma 10.3 NKX2-1 KRT7
50 paratesticular lipoma 10.3 KRT19 ENO2

Graphical network of the top 20 diseases related to Nasal Cavity Olfactory Neuroblastoma:



Diseases related to Nasal Cavity Olfactory Neuroblastoma

Symptoms & Phenotypes for Nasal Cavity Olfactory Neuroblastoma

MGI Mouse Phenotypes related to Nasal Cavity Olfactory Neuroblastoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.65 CDX2 ENO2 KRT19 KRT7 MME NCAM1
2 nervous system MP:0003631 9.32 ENO2 KRT19 MME NCAM1 NKX2-1 PAX2

Drugs & Therapeutics for Nasal Cavity Olfactory Neuroblastoma

Search Clinical Trials , NIH Clinical Center for Nasal Cavity Olfactory Neuroblastoma

Genetic Tests for Nasal Cavity Olfactory Neuroblastoma

Anatomical Context for Nasal Cavity Olfactory Neuroblastoma

Publications for Nasal Cavity Olfactory Neuroblastoma

Articles related to Nasal Cavity Olfactory Neuroblastoma:

# Title Authors PMID Year
1
[Extensive olfactory neuroblastoma of the nasal cavity and paranasal sinuses]. 61
20684358 2010
2
[Olfactory neuroblastoma of the nasal cavity (author's transl)]. 61
7341184 1981
3
Olfactory neuroblastoma (esthesioneuroblastoma): a light and ultrastructural study of two cases. 61
383258 1979

Variations for Nasal Cavity Olfactory Neuroblastoma

Expression for Nasal Cavity Olfactory Neuroblastoma

Search GEO for disease gene expression data for Nasal Cavity Olfactory Neuroblastoma.

Pathways for Nasal Cavity Olfactory Neuroblastoma

Pathways related to Nasal Cavity Olfactory Neuroblastoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.89 SYP NKX2-1 NCAM1 ENO2 CALCA
2 11.56 NCAM1 MME CEACAM5
3
Show member pathways
11.47 KRT7 KRT5 KRT19
4 11.23 SYP PAX2 NCAM1
5 11.05 PAX2 NCAM1 KRT19 CDX2
6 10.57 PAX8 PAX2

GO Terms for Nasal Cavity Olfactory Neuroblastoma

Biological processes related to Nasal Cavity Olfactory Neuroblastoma according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.74 KRT7 KRT5 KRT19
2 lung development GO:0030324 9.72 PTN NKX2-1 MME
3 regulation of myelination GO:0031641 9.59 TG PTN
4 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.58 PAX8 PAX2
5 urogenital system development GO:0001655 9.58 PAX8 PAX2
6 mesonephros development GO:0001823 9.56 PAX8 PAX2
7 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.54 PAX8 PAX2
8 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.52 PAX8 PAX2
9 pronephros development GO:0048793 9.51 PAX8 PAX2
10 metanephric epithelium development GO:0072207 9.49 PAX8 PAX2
11 metanephric nephron tubule formation GO:0072289 9.48 PAX8 PAX2
12 metanephric distal convoluted tubule development GO:0072221 9.46 PAX8 PAX2
13 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.43 PAX8 PAX2
14 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.4 PAX8 PAX2
15 positive regulation of metanephric DCT cell differentiation GO:2000594 9.37 PAX8 PAX2
16 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.32 PAX8 PAX2
17 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.26 PAX8 PAX2
18 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.16 PAX8 PAX2
19 pronephric field specification GO:0039003 8.96 PAX8 PAX2
20 thyroid gland development GO:0030878 8.8 TG PAX8 NKX2-1

Sources for Nasal Cavity Olfactory Neuroblastoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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