MCID: NSL006
MIFTS: 30

Nasal Cavity Squamous Cell Carcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Nasal Cavity Squamous Cell Carcinoma

MalaCards integrated aliases for Nasal Cavity Squamous Cell Carcinoma:

Name: Nasal Cavity Squamous Cell Carcinoma 12 15 17 70
Squamous Cell Carcinoma of the Nasal Cavity 12
Squamous Cell Carcinoma of Nasal Cavity 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5515
MeSH 44 D000077195
NCIt 50 C8192
UMLS 70 C0280333

Summaries for Nasal Cavity Squamous Cell Carcinoma

Disease Ontology : 12 A nasal cavity carcinoma that has material basis in squamous cells.

MalaCards based summary : Nasal Cavity Squamous Cell Carcinoma, also known as squamous cell carcinoma of the nasal cavity, is related to squamous cell carcinoma, head and neck and squamous cell carcinoma, and has symptoms including pain and rhinorrhea. An important gene associated with Nasal Cavity Squamous Cell Carcinoma is MMP2 (Matrix Metallopeptidase 2), and among its related pathways/superpathways are Angiogenesis (CST) and Regulation of Wnt-mediated beta catenin signaling and target gene transcription. Affiliated tissues include heart, lymph node and neutrophil.

Related Diseases for Nasal Cavity Squamous Cell Carcinoma

Diseases related to Nasal Cavity Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
# Related Disease Score Top Affiliating Genes
1 squamous cell carcinoma, head and neck 11.7
2 squamous cell carcinoma 10.3
3 granulomatosis with polyangiitis 10.2
4 rare tumor 10.2
5 extracranial arteriovenous malformation 10.2 MMP9 MMP2
6 arteriovenous malformation 10.2 MMP9 MMP2
7 focal myositis 10.2 MMP9 MMP2
8 spastic entropion 10.2 MMP9 MMP2
9 acute transverse myelitis 10.2 MMP9 MMP2
10 transverse myelitis 10.2 MMP9 MMP2
11 lentigo maligna melanoma 10.2 MMP9 MMP2
12 light chain deposition disease 10.2 MMP9 MMP2
13 senile ectropion 10.2 MMP9 MMP2
14 odontogenic myxoma 10.2 MMP9 MMP2
15 mucositis 10.2
16 dry eye syndrome 10.2
17 squamous cell papilloma 10.2
18 papilloma 10.2
19 inverted papilloma 10.2
20 nasal cavity benign neoplasm 10.2 MMP9 MMP2
21 parotitis 10.1 MMP9 MMP2
22 periapical periodontitis 10.1 MMP9 MMP2
23 conjunctivochalasis 10.1 MMP9 MMP2
24 dental fluorosis 10.1 MMP9 MMP2
25 ischemic colitis 10.1 MMP9 MMP2
26 corneal ulcer 10.1 MMP9 MMP2
27 lung giant cell carcinoma 10.1 MMP9 MMP2
28 diastolic heart failure 10.1 MMP9 MMP2
29 oral submucous fibrosis 10.1 MMP9 MMP2
30 systolic heart failure 10.1 MMP9 MMP2
31 dysphagia 10.1
32 adenomyosis 10.1 MMP9 MMP2
33 supravalvular aortic stenosis 10.1 MMP9 MMP2
34 hypertensive heart disease 10.1 MMP9 MMP2
35 pelvic organ prolapse 10.1 MMP9 MMP2
36 preterm premature rupture of the membranes 10.1 MMP9 MMP2
37 pneumothorax 10.1 MMP9 MMP2
38 pelvic inflammatory disease 10.1 MMP9 MMP2
39 actinic keratosis 10.1 MMP9 MMP2
40 limb ischemia 10.1 MMP9 MMP2
41 oral cancer 10.1 MMP9 MMP2
42 ameloblastoma 10.1 MMP9 MMP2
43 aortic aneurysm, familial thoracic 1 10.0 MMP9 MMP2
44 varicose veins 10.0 MMP9 MMP2
45 takayasu arteritis 10.0 MMP9 MMP2
46 aggressive periodontitis 10.0 MMP9 MMP2
47 hyperostosis 9.9 MMP9 MMP2
48 tongue disease 9.9 MMP9 MMP2
49 lymphangioleiomyomatosis 9.8 MMP9 MMP2
50 macular degeneration, age-related, 1 9.6 MMP9 MMP2 IMPG1

Graphical network of the top 20 diseases related to Nasal Cavity Squamous Cell Carcinoma:



Diseases related to Nasal Cavity Squamous Cell Carcinoma

Symptoms & Phenotypes for Nasal Cavity Squamous Cell Carcinoma

UMLS symptoms related to Nasal Cavity Squamous Cell Carcinoma:


pain; rhinorrhea

Drugs & Therapeutics for Nasal Cavity Squamous Cell Carcinoma

Search Clinical Trials , NIH Clinical Center for Nasal Cavity Squamous Cell Carcinoma

Genetic Tests for Nasal Cavity Squamous Cell Carcinoma

Anatomical Context for Nasal Cavity Squamous Cell Carcinoma

MalaCards organs/tissues related to Nasal Cavity Squamous Cell Carcinoma:

40
Heart, Lymph Node, Neutrophil, Eye, Lung, Tongue

Publications for Nasal Cavity Squamous Cell Carcinoma

Articles related to Nasal Cavity Squamous Cell Carcinoma:

(show all 37)
# Title Authors PMID Year
1
Impact of pretherapeutic neutrophil-to-lymphocyte ratio, serum albumin, body-mass index, and advanced lung cancer inflammation index on clinical outcome in sinonasal squamous cell carcinoma. 61
31810849 2020
2
Squamous cell carcinoma of the nasal cavity: A descriptive analysis of cases from the head and neck 5000 study. 61
31419373 2019
3
Organ preservation for patients with anterior mucosal squamous cell carcinoma of the nasal cavity: Rhinectomy-free survival in those refusing surgery. 61
30933393 2019
4
Copy number variation in progression of inverted papilloma to squamous cell carcinoma of the nasal cavity. 61
31949863 2018
5
A case of squamous cell carcinoma of the nasal cavity in a patient with granulomatosis with polyangiitis (Wegener granulomatosis). 61
29493730 2018
6
Combination Intensity Modulated Proton Therapy and Passive Scatter Boost for Rapidly Progressing Nasal Cavity Squamous Cell Carcinoma. 61
29152442 2017
7
[Clinicopathologic features of non-keratinizing carcinoma of nasal cavity and paranasal sinus]. 61
27646894 2016
8
[Nasal cavity and paranasal sinus cancer]. 61
27528562 2016
9
Risk of lymph node metastasis and recommendations for elective nodal treatment in squamous cell carcinoma of the nasal cavity and maxillary sinus: a SEER analysis. 61
27685421 2016
10
A clinical study of multimodal treatment for orbital organ preservation in locally advanced squamous cell carcinoma of the nasal cavity and paranasal sinus. 61
27207888 2016
11
Squamous cell carcinoma of the nasal cavity: A population-based analysis. 61
26297930 2016
12
Management for squamous cell carcinoma of the nasal cavity and ethmoid sinus: A single institution experience. 61
25748513 2015
13
Expression of c-Met Is Different along the Location and Associated with Lymph Node Metastasis of Head and Neck Carcinoma. 61
23323101 2012
14
Basaloid squamous cell carcinoma of the nasal septum presenting as a primary cutaneous lesion. 61
22971318 2012
15
Treatment of malignant sinonasal tumours with intensity-modulated radiotherapy (IMRT) and carbon ion boost (C12). 61
21600049 2011
16
[Expression and significance of matrix metalloproteinase and tissue inhibitor of metalloproteinase in nasal cavity squamous cell carcinoma]. 61
21624249 2011
17
Microsatellite instability analysis of sinonasal carcinomas. 61
19130962 2009
18
Wood dust exposure and the risk of upper aero-digestive and respiratory cancers in males. 61
18182588 2008
19
Regional recurrence of squamous cell carcinoma of the nasal cavity: a systematic review and meta-analysis. 61
17709619 2007
20
Investigation and management of adult periorbital and orbital cellulitis. 61
17164026 2007
21
[Epidemiologic analysis of 72 carcinomas of the nasal cavity and paranasal sinuses]. 61
17117693 2006
22
Nasal cavity squamous cell carcinoma presenting as a nasal sidewall nodule: treatment with Mohs surgery, partial rhinectomy, and adjuvant radiotherapy. 61
16681669 2006
23
Cerebral radionecrosis with cystic degeneration following radiotherapy for nasal cavity squamous cell carcinoma: a case report. 61
15253473 2004
24
Efficacy of cobalt-60 radiation therapy for the treatment of nasal cavity nonkeratinizing squamous cell carcinoma in the dog. 61
12549620 2003
25
Nasal cavity squamous cell carcinoma in Wegener's granulomatosis. 61
11405874 2001
26
Caffeine-derived N-nitroso compounds. V. Carcinogenicity of mononitrosocaffeidine and dinitrosocaffeidine in bd-ix rats. 61
9635885 1998
27
Cobalt 60 radiotherapy for treatment of squamous cell carcinoma of the nasal cavity and paranasal sinuses in three horses. 61
9530425 1998
28
Metastatic carcinoma to the male and female breast. 61
9509597 1998
29
Clinical assessment of squamous cell carcinoma of the nasal cavity proper. 61
8561698 1995
30
Radiotherapy for squamous cell carcinoma of the nasal cavity. 61
8372243 1993
31
The determination of parts per billion concentrations of hexamethylphosphoramide and its metabolite, pentamethylphosphoramide, in urine. 61
3434539 1987
32
Risk assessment of laboratory rats and mice chronically exposed to formaldehyde vapors. 61
3916550 1985
33
[Squamous cell carcinoma of the nasal cavity (data from the Institute of Oncology in Cracow)]. 61
3834362 1985
34
Nasal cancer in a worker exposed to formaldehyde. 61
6848853 1983
35
Squamous cell carcinoma of the nasal cavity. 61
706430 1978
36
Epithelial papilloma and squamous cell carcinoma of the nasal cavity and paranasal sinuses: a clinicopathological study. 61
1000480 1976
37
Squamous cell carcinoma of the nasal cavity. 61
18897184 1947

Variations for Nasal Cavity Squamous Cell Carcinoma

Expression for Nasal Cavity Squamous Cell Carcinoma

Search GEO for disease gene expression data for Nasal Cavity Squamous Cell Carcinoma.

Pathways for Nasal Cavity Squamous Cell Carcinoma

GO Terms for Nasal Cavity Squamous Cell Carcinoma

Cellular components related to Nasal Cavity Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular matrix GO:0031012 8.8 MMP9 MMP2 IMPG1

Biological processes related to Nasal Cavity Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ephrin receptor signaling pathway GO:0048013 9.46 MMP9 MMP2
2 extracellular matrix disassembly GO:0022617 9.43 MMP9 MMP2
3 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.4 MMP9 MMP2
4 collagen catabolic process GO:0030574 9.37 MMP9 MMP2
5 cellular response to reactive oxygen species GO:0034614 9.32 MMP9 MMP2
6 embryo implantation GO:0007566 9.26 MMP9 MMP2
7 endodermal cell differentiation GO:0035987 9.16 MMP9 MMP2
8 response to amyloid-beta GO:1904645 8.96 MMP9 MMP2
9 cellular response to UV-A GO:0071492 8.62 MMP9 MMP2

Sources for Nasal Cavity Squamous Cell Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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