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MCID: NSP003
MIFTS: 37

Nasopharyngeal Disease

Categories: Respiratory diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Nasopharyngeal Disease

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MalaCards integrated aliases for Nasopharyngeal Disease:

Name: Nasopharyngeal Disease 12 15
Nasopharyngeal Diseases 55 44 73

Classifications:

MalaCards categories:
Anatomical: Respiratory diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:9561
MeSH 44 D009302
NCIt 50 C35723
UMLS 73 C0027438
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Summaries for Nasopharyngeal Disease

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MalaCards based summary : Nasopharyngeal Disease, also known as nasopharyngeal diseases, is related to nasopharyngitis and rare adenocarcinoma of the breast. An important gene associated with Nasopharyngeal Disease is PSMB9 (Proteasome Subunit Beta 9), and among its related pathways/superpathways are Human cytomegalovirus infection and fMLP Pathway. The drugs Erythromycin and Erythromycin Ethylsuccinate have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and brain, and related phenotypes are Decreased viability and Decreased viability

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Related Diseases for Nasopharyngeal Disease

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Diseases related to Nasopharyngeal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 117)
# Related Disease Score Top Affiliating Genes
1 nasopharyngitis 11.0
2 rare adenocarcinoma of the breast 10.3 AKT1 TP53
3 bartholin's duct cyst 10.3 SMUG1 TP53
4 breast papillomatosis 10.3 CCND1 CDKN2A
5 cerebral convexity meningioma 10.3 CDH1 TP53
6 bile duct adenocarcinoma 10.3 AKT1 CDH1 TP53
7 malignant spiradenoma 10.3 SMUG1 TP53
8 ovarian cancer 1 10.3 AKT1 CDH1 TP53
9 anal squamous cell carcinoma 10.3 AKT1 CDKN2A TP53
10 cellular ependymoma 10.3 SMUG1 TP53
11 short-rib thoracic dysplasia 4 with or without polydactyly 10.3 CASP3 TP53
12 malignant ovarian surface epithelial-stromal neoplasm 10.3 AKT1 CDH1 TP53
13 ovary epithelial cancer 10.3 AKT1 CDH1 TP53
14 protoplasmic astrocytoma 10.3 SMUG1 TP53
15 pharynx squamous cell carcinoma 10.3 AKT1 CASP3 SMUG1
16 tongue disease 10.3 CDH1 CDKN2A TP53
17 tonsil squamous cell carcinoma 10.3 CCND1 CDKN2A
18 tonsil cancer 10.3 CDH1 CDKN2A TP53
19 verrucous carcinoma 10.3 CCND1 CDKN2A TP53
20 connective tissue cancer 10.3 AKT1 SMUG1 TP53
21 estrogen-receptor positive breast cancer 10.3 AKT1 CCND1 TP53
22 epstein-barr virus-associated gastric carcinoma 10.3 CDH1 CDKN2A PSMB9
23 colloid adenoma 10.3 SMUG1 TP53
24 pleural cancer 10.3 AKT1 CDKN2A SMUG1
25 in situ carcinoma 10.3 CDH1 CDKN2A TP53
26 bladder squamous cell carcinoma 10.3 CDKN2A TP53
27 inverted papilloma 10.3 CCND1 CDKN2A TP53
28 penile cancer 10.3 CCND1 CDKN2A TP53
29 cholecystitis 10.3 CDH1 CDKN2A TP53
30 cervical squamous cell carcinoma 10.3 CDH1 CDKN2A TP53
31 megaesophagus 10.3 CDKN2A MYC TP53
32 suppressor of tumorigenicity 3 10.3 CDKN2A MYC TP53
33 breast ductal carcinoma 10.2 CCND1 CDH1 TP53
34 ductal carcinoma in situ 10.2 AKT1 CCND1 CDH1 TP53
35 anaplastic thyroid cancer 10.2 CASP3 CDH1 TP53
36 pleomorphic adenoma carcinoma 10.2 BPIFB1 TP53
37 keratinizing squamous cell carcinoma 10.2 CDKN2A TP53
38 endometrial adenocarcinoma 10.2 AKT1 CDKN2A TP53
39 pre-malignant neoplasm 10.2 CCND1 CDH1 CDKN2A TP53
40 laryngeal disease 10.2 CCND1 CDH1 CDKN2A TP53
41 skin melanoma 10.2 CASP3 CDKN2A TP53
42 esophageal disease 10.2 CCND1 CDKN2A SMUG1 TP53
43 bowenoid papulosis 10.2 CCND1 CDKN2A
44 laryngeal squamous cell carcinoma 10.2 CCND1 CDH1 CDKN2A TP53
45 upper respiratory tract disease 10.2 CDKN2A TMEM8B TP53
46 gallbladder cancer 10.2 AKT1 CDH1 CDKN2A TP53
47 supratentorial cancer 10.2 AKT1 CASP3 CDKN2A TP53
48 cerebrum cancer 10.2 AKT1 CASP3 CDKN2A TP53
49 suppression of tumorigenicity 12 10.2 AKT1 CDH1 TP53
50 gastrointestinal stromal tumor 10.2 AKT1 CCND1 CDKN2A TP53

Graphical network of the top 20 diseases related to Nasopharyngeal Disease:



Diseases related to Nasopharyngeal Disease
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Symptoms & Phenotypes for Nasopharyngeal Disease

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GenomeRNAi Phenotypes related to Nasopharyngeal Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00221-A-1 9.96 AKT1 CDH1 CDKN2A MAPK9 MYC
2 Decreased viability GR00221-A-2 9.96 AKT1 MAPK9
3 Decreased viability GR00221-A-3 9.96 AKT1 CDKN2A MAPK9 MYC
4 Decreased viability GR00221-A-4 9.96 AKT1 CDKN2A
5 Decreased viability GR00301-A 9.96 CDH1 MAPK9
6 Decreased viability GR00402-S-2 9.96 AKT1 CDH1 CDKN2A MAPK9 MYC
7 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.4 AKT1 CASP3 CDKN2A PSMB9 TP53
8 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.4 AKT1 CASP3 CCND1 CDKN2A MYC PSMB9

MGI Mouse Phenotypes related to Nasopharyngeal Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.17 AKT1 BPIFB1 BRD7 CASP3 CCND1 CDH1
2 immune system MP:0005387 10.11 AKT1 BPIFA1 CASP3 CCND1 CDH1 CDKN2A
3 mortality/aging MP:0010768 10.07 AKT1 B4GALT5 BPIFA1 BRD7 CASP3 CCND1
4 integument MP:0010771 9.97 AKT1 BRD7 CASP3 CCND1 CDH1 CDKN2A
5 digestive/alimentary MP:0005381 9.95 CASP3 CCND1 CDH1 CDKN2A MAPK9 MYC
6 neoplasm MP:0002006 9.81 AKT1 CCND1 CDH1 CDKN2A MAPK9 MYC
7 reproductive system MP:0005389 9.61 AKT1 BPIFB1 CASP3 CCND1 CDH1 CDKN2A
8 respiratory system MP:0005388 9.28 AKT1 BPIFA1 BPIFB1 CASP3 CCND1 CDKN2A
Sources

Drugs & Therapeutics for Nasopharyngeal Disease

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Drugs for Nasopharyngeal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 297)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Erythromycin Approved, Investigational, Vet_approved Phase 4 114-07-8 12560
2 Erythromycin Ethylsuccinate Phase 4
3 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
4 Erythromycin stearate Phase 4
5 Erythromycin Estolate Phase 4
6 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
7 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
8 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
9 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
10 Cyclooxygenase 2 Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
11 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
12 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
13 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
14 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
15 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
16
Docetaxel Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 114977-28-5 148124
17
Cisplatin Approved Phase 3,Phase 2,Phase 1,Not Applicable 15663-27-1 2767 441203 84093
18
Gemcitabine Approved Phase 3,Phase 2,Phase 1,Not Applicable 95058-81-4 60750
19
Fluorouracil Approved Phase 3,Phase 2,Phase 1,Not Applicable 51-21-8 3385
20
Celecoxib Approved, Investigational Phase 3,Phase 2,Phase 1 169590-42-5 2662
21
Nedaplatin Approved, Investigational Phase 3,Phase 2,Phase 1 95734-82-0
22
Hydroxyurea Approved Phase 3,Phase 1 127-07-1 3657
23
Ursodeoxycholic acid Approved, Investigational Phase 2, Phase 3,Phase 3 128-13-2 31401
24
leucovorin Approved Phase 3,Phase 2 58-05-9 6006 143
25
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 33069-62-4 36314
26
Capecitabine Approved, Investigational Phase 2, Phase 3,Phase 3,Not Applicable 154361-50-9 60953
27
Cetuximab Approved Phase 3,Phase 2,Phase 1 205923-56-4 56842117 2333
28
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
29
Sulindac Approved, Investigational Phase 3,Phase 2 38194-50-2 5352 1548887
30
Budesonide Approved Phase 3,Not Applicable 51333-22-3 63006 5281004
31
Prednisone Approved, Vet_approved Phase 3,Not Applicable 53-03-2 5865
32
Fluticasone Approved, Experimental Phase 3 90566-53-3 62924
33
Amifostine Approved, Investigational Phase 3,Phase 2 20537-88-6 2141
34
Epirubicin Approved Phase 3 56420-45-2 41867
35
Oprelvekin Approved, Investigational Phase 3 145941-26-0
36
mometasone furoate Approved, Vet_approved Phase 3,Phase 2 83919-23-7
37
Levoleucovorin Approved, Investigational Phase 3 68538-85-2
38
Pembrolizumab Approved Phase 3,Phase 2,Phase 1 1374853-91-4
39
Acyclovir Approved Phase 3 59277-89-3 2022
40
Tegafur Approved, Investigational Phase 3 17902-23-7 5386
41
Vinorelbine Approved, Investigational Phase 3 71486-22-1 60780 44424639
42
Methotrexate Approved Phase 3 59-05-2, 1959-05-2 126941
43
Serine Approved, Nutraceutical Phase 3 56-45-1 5951
44
Ornithine Approved, Nutraceutical Phase 3,Phase 2 3184-13-2, 70-26-8 6262
45 Antimetabolites Phase 3,Phase 2,Phase 1,Not Applicable
46 Endostatins Phase 3,Phase 2 71581480
47 Antiviral Agents Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1,Not Applicable
49 Angiogenesis Modulating Agents Phase 3,Phase 2,Phase 1
50 Immunosuppressive Agents Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 423)
# Name Status NCT ID Phase Drugs
1 Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyposis-minors' Adjusted Version Unknown status NCT02354560 Phase 4 Erythromycin
2 Phase IV Clinical Trial of Nimotuzumab in the Treatment of Nasopharyngeal Carcinoma Unknown status NCT02293356 Phase 4 Nimotuzumab Injection
3 Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis Unknown status NCT02175914 Phase 4 Erythromycin
4 Stereotactic Body Radiotherapy for Head and Neck Tumors Completed NCT01344356 Phase 4
5 A Research About Nutrition Impact for Local Advanced Nasopharyngeal Carcinoma Patients Active, not recruiting NCT02948699 Phase 4
6 A Study of Rofecoxib in Familial Adenomatous Polyposis (FAP) (0966-205)(TERMINATED) Terminated NCT00140894 Phase 4 MK0966; rofecoxib / Duration of Treatment: 24 weeks;Comparator: placebo / Duration of Treatment: 24 weeks
7 EUS-FNA for Retropharyngeal Lymph Node (RPLN) in Recurrent Nasopharyngeal Carcinoma (NPC) Patients Unknown status NCT03006588 Phase 2, Phase 3
8 Trial Evaluating Maintenance Chemotherapy for Metastatic Nasopharyngeal Carcinoma Unknown status NCT02944708 Phase 3 Conventional chemotherapy;Maintenance chemotherapy 1;Maintenance chemotherapy 2
9 A Trial of Endostar in Combination With Chemotherapy of DF and Sequential Intensity Modulated Radiation Therapy for Patients With Advanced Nasopharyngeal Carcinoma Unknown status NCT02444949 Phase 3 endostar;cisplatin
10 The Effect of COX-2 Inhibitor on Radiosensitivity in Nasopharyngeal Carcinoma Unknown status NCT02537925 Phase 3 Celecoxib;Nedaplatin
11 Weekly Cisplatin or Nedaplatin Concurrent With Intensity-modulated Radiation Therapy in Nasopharyngeal Carcinoma Unknown status NCT02301208 Phase 3 Nedaplatin;Cisplatin
12 Phase â…¢ Study of Neoadjuvant TPF Chemotherapy Followed by Radiotherapy and Concurrent Nimotuzumab or Cisplatin for Locoregionally Advanced Nasopharyngeal Carcinoma (NPC). Unknown status NCT02012062 Phase 3 TPF neoadjuvant chemotherapy;Concurrent chemotherapy with cisplatin during radiotherapy;Concurrent nimotuzumab during radiotherapy
13 Endostatin in Combination With Chemotherapy for Metastatic Nasopharyngeal Carcinoma Unknown status NCT01915134 Phase 3 Recombinant Human Endostatin plus gemcitabine and cisplatin;Gemcitabine and cisplatin
14 Combination of Cisplatin Plus Gemcitabine Induction Chemotherapy and Intensity-modulated radiotherapyIntensity-modulated Radiotherapy With or Without Concurrent Cisplatin for NPC Unknown status NCT01854203 Phase 2, Phase 3 Inductive chemotherapy + concurrent cisplatin and IMRT;Inductive chemotherapy + IMRT
15 The Role of Concurrent Chemotherapy for Lower Risk Locally Advanced Nasopharyngeal Carcinoma(NPC) in the Era of IMRT Unknown status NCT01817023 Phase 3 Cisplatin
16 Recombine Endostatin With Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation in Advanced Nasopharynx Cancer Unknown status NCT01689558 Phase 2, Phase 3 Recombine Endostatin
17 Efficacy Study of Neoadjuvant Chemotherapy With Chemoradiation Therapy for Nasopharyngeal Carcinoma Unknown status NCT01536223 Phase 3 PF (cisplatin and 5-fluorouracil) group;TPF (docetaxel plus cisplatin and 5-fluorouracil) group
18 Effect and Safety Study of GP/FP Regimens in Advanced Nasopharyngeal Carcinoma Unknown status NCT01528618 Phase 3 gemcitabine and cisplatin;5-Fluorouracil and cisplatin
19 A Multicenter Trial Evaluating the Efficacy of Nedaplatin in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma Unknown status NCT01479504 Phase 3 nedaplatin and docetaxel;cisplatin and docetaxel;nedaplatin and docetaxel;cisplatin and docetaxel
20 Nimotuzumab in Combination With Chemoradiation for Nasopharyngeal Cancer Unknown status NCT01074021 Phase 3 Nimotuzumab;placebo plus chemoradiotherapy
21 Induction Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma Unknown status NCT01245959 Phase 3 Docetaxel, cisplatin and fluorouracil
22 A Multicenter Trial Comparing Multi-course Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma Unknown status NCT00705627 Phase 3 neoadjuvant chemotherapy plus concurrent chemoradiotherapy
23 Adjuvant Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma Unknown status NCT00677118 Phase 3 Cisplatin,fluorouracil;Cisplatin
24 PHASE III TRIAL COMPARING, NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY VERSUS THE SAME NEOADJUVANT CHEMOTHERAPY FOLLOWED BY STANDARD RADIOTHERAPY ASSOCIATED WITH DAILY HYDROXYUREA IN THE TREATMENT OF LOCALLY ADVANCED UNDIFFERENTIATED CARCINOMA NASOPHARYNGEAL TYPE. Unknown status NCT00180973 Phase 3 Hydroxyurea
25 Ursodeoxycholic Acid in the Treatment of Duodenal Adenomas in Familial Adenomatous Polyposis (FAP) Patients Unknown status NCT00134758 Phase 2, Phase 3 Ursodeoxycholic acid;Placebo
26 Efficacy and Safety of Budesonide Inhalation Suspension for the Treatment of Chronic Rhinosinusitis With Polyposis. Completed NCT03687515 Phase 3 budesonide;budesonide;Prednisone
27 Study Evaluating the Efficacy and Safety of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi Directional Device in Subjects With Bilateral Nasal Polyposis Followed by an 8-Week Open-Label Extension Phase to Assess Safety Completed NCT01622569 Phase 3 Fluticasone Propionate
28 Concurrent Chemoradiotherapy With Nedaplatin Versus Cisplatin in Nasopharyngeal Carcinoma Completed NCT01540136 Phase 3 Nedaplatin;Cisplatin
29 Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis Completed NCT01197612 Phase 3 pulmicort
30 Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis Completed NCT00808743 Phase 2, Phase 3 Celecoxib;Ursodeoxycholic acid;Placebo
31 Late-Course Accelerated Hyperfractionated IMRT for Locoregionally Advanced Nasopharyngeal Carcinoma Completed NCT00778908 Phase 2, Phase 3 Concomitant cisplatin chemotherapy
32 Phase III: Assess Conventional RT w/ Conventional Plus Accelerated Boost RT in the Treatment of Nasopharyngeal CA Completed NCT00535795 Phase 3
33 Chemoprevention Trial in Familial Adenomatous Polyposis (FAP) Coli Using EPA Completed NCT00510692 Phase 2, Phase 3 Eicosapentanoic Acid (EPA);Placebo
34 Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer Completed NCT00274937 Phase 3 amifostine trihydrate;fluorouracil;cisplatin
35 A Multicenter Trial Comparing Induction C/T Followed by CCRT v.s. CCRT Alone in Stage IV Nasopharyngeal Carcinoma Completed NCT00201396 Phase 3 Mitomycin C,Epirubicin,Cisplatin,5-Fluorouracil,Leucovorin
36 Adjuvant PD-1 Antibody in Locoregionally Advanced Nasopharyngeal Carcinoma After Chemoradiotherapy Recruiting NCT03427827 Phase 3 PD-1 antibody
37 Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis Recruiting NCT03806426 Phase 3 Eicosapentaenoic acid free fatty acid (EPA-FFA);Placebo
38 Acute Radiation Oral Mucositis in Nasopharyngeal Carcinoma(NPC) Patients Treated With Combined Radio-Chemotherapy Recruiting NCT03720340 Phase 3 Recombinant Human Interleukin-11;Saline
39 Phase III Study of Camrelizumab in Combination With Chemotherapy in Recurrent/Metastatic Nasopharyngeal Carcinoma Recruiting NCT03707509 Phase 3 Camrelizumab;Placebos;Gemcitabine;Cisplatin
40 GP Induction Chemotherapy us TPF Adjuvant Chemotherapy Combined With DDP Concurrent Chemoradiotherapy in the Treatment of Locally Advanced NPC Recruiting NCT03604965 Phase 3 GP+CCRT;TPF+CCRT
41 Gemcitabine and Cisplatin With/Without Anlotinib in Advanced Nasopharyngeal Carcinoma Recruiting NCT03601975 Phase 3 Gemcitabine/Cisplatin
42 TPF Induction Chemotherapy vs PF Adjuvant Chemotherapy Combined With Concurrent Chemoradiotherapy in the Treatment of Locally Advanced NPC Recruiting NCT03574324 Phase 3 TPF+CCRT;CCRT+PF
43 Maintenance Chemotherapy in High-metastatic Risk Nasopharyngeal Carcinoma Patients of N3 Stage Recruiting NCT03403829 Phase 3 Gemcitabine
44 Efficacy and Safety Study of Benralizumab for Patients With Severe Nasal Polyposis Recruiting NCT03401229 Phase 3
45 Efficacy of Ulinastatin for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients Recruiting NCT03387774 Phase 3 Cisplatin;Ulinastatin
46 Sequential or Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced NPC Recruiting NCT03366415 Phase 3 gemcitabine and cisplatin (Induction and adjuvant chemotherapy);gemcitabine and cisplatin (Induction chemotherapy)
47 Mometasone vs Budesonide in CRS With Polyposis Recruiting NCT03323866 Phase 3 Budesonide 0.5 MG/ML;Mometasone nasal spray
48 Phase â…¢ Trial of Adjuvant Chemotherapy in Patients With N2-3 Nasopharyngeal Carcinoma Recruiting NCT03321539 Phase 3 CCRT+GP;CCRT+PF
49 TPF+CCRT vs.CCRT+PF in High Risk Nasopharyngeal Carcinoma Recruiting NCT03306121 Phase 3 TPF+CCRT;CCRT+ PF
50 Induction Chemotherapy Followed by Radiotherapy Alone or Concurrent Chemoradiotherapy in Nasopharyngeal Carcinoma Recruiting NCT03015727 Phase 3 Docetaxel;Cisplatin;Chemotherapy

Search NIH Clinical Center for Nasopharyngeal Disease

Cochrane evidence based reviews: nasopharyngeal diseases

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Genetic Tests for Nasopharyngeal Disease

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Anatomical Context for Nasopharyngeal Disease

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MalaCards organs/tissues related to Nasopharyngeal Disease:

41
Lung, Skin, Brain, Bone, Colon, Tongue, Thyroid
Sources

Publications for Nasopharyngeal Disease

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Articles related to Nasopharyngeal Disease:

# Title Authors Year
1
Expression of GRIN2A in benign and malignant nasopharyngeal diseases and its clinical significance. ( 26681223 )
2015
2
Expression and clinical significance of LRRC4 in benign and malignant nasopharyngeal diseases. ( 26662436 )
2015
3
Nasopharyngeal disease in cats: 1. Diagnostic investigation. ( 22511473 )
2012
4
Nasopharyngeal disease in cats: 2. Specific conditions and their management. ( 22511474 )
2012
5
Nasopharyngeal diseases in cats: a retrospective study of 53 cases (1991-1998). ( 10580903 )
1999
6
Management of some benign nasopharyngeal diseases in the adult; supplementary report. ( 13356856 )
1956
7
Surgical treatment of benign nasopharyngeal disease in the adult. ( 14943338 )
1952
8
A new pharyngoscope; facilitating diagnosis and treatment of nasopharyngeal diseases. ( 20994675 )
1946
Sources

Variations for Nasopharyngeal Disease

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Expression for Nasopharyngeal Disease

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Search GEO for disease gene expression data for Nasopharyngeal Disease.
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Pathways for Nasopharyngeal Disease

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Pathways related to Nasopharyngeal Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Super pathways Score Top Affiliating Genes
1
Human cytomegalovirus infection 37
Show member pathways
 13.09 AKT1 CASP3 CCND1 CDKN2A MAPK9 MYC
2
fMLP Pathway 64
Show member pathways
 13.05 AKT1 CASP3 CDH1 MAPK9 PSMB9 TP53
3
Apoptosis Modulation and Signaling 1
Show member pathways
 12.85 AKT1 CASP3 CDKN2A MAPK9 MYC TP53
4
Influenza A 37
Show member pathways
 12.83 AKT1 CASP3 CCND1 MAPK9 TP53
5
Endometrial cancer 37
Show member pathways
 12.82 AKT1 CASP3 CCND1 CDH1 CDKN2A MAPK9
6
Glioma 37
Show member pathways
 12.81 AKT1 CCND1 CDH1 CDKN2A MAPK9 TP53
7
MAPK signaling pathway 37 1
12.8 AKT1 CASP3 MAPK9 MYC TP53
8
Gastric cancer 37
Show member pathways
 12.76 AKT1 BRD7 CCND1 CDH1 CDKN2A MYC
9
Development HGF signaling pathway 22
Show member pathways
 12.75 AKT1 CASP3 CDH1 MAPK9 TP53
10
Pathways in cancer 37
12.73 AKT1 CASP3 CCND1 CDH1 CDKN2A MAPK9
11
Chks in Checkpoint Regulation 64
Show member pathways
 12.69 CASP3 CCND1 MAPK9 MYC PSMB9 SMUG1
12
Mitotic G1-G1/S phases 66
Show member pathways
 12.6 AKT1 CCND1 CDKN2A MYC PSMB9 TP53
13
MicroRNAs in cancer 37
12.57 CASP3 CCND1 CDKN2A MYC TP53
14
Prolactin Signaling Pathway 1 37
Show member pathways
 12.54 AKT1 CASP3 CCND1 MAPK9 MYC
15
ErbB signaling pathway 1 37
Show member pathways
 12.53 AKT1 CCND1 MAPK9 MYC TP53
16
Apoptosis Pathway 72
Show member pathways
 12.47 AKT1 CASP3 MAPK9 TP53
17
Human T-cell leukemia virus 1 infection 37
12.47 AKT1 CCND1 CDKN2A MYC TP53
18
Development EGFR signaling pathway 22
Show member pathways
 12.46 AKT1 CASP3 CCND1 CDH1 MAPK9 MYC
19
Development IGF-1 receptor signaling 22
Show member pathways
 12.43 AKT1 CCND1 MYC TP53
20
DNA Damage Response 1
Show member pathways
 12.42 CASP3 CCND1 CDKN2A MYC TP53
21
Cell cycle 1 37
12.4 CCND1 CDH1 CDKN2A MYC TP53
22
Viral carcinogenesis 37
12.33 CASP3 CCND1 CDKN2A TP53
23
Proteoglycans in cancer 37
12.33 AKT1 CASP3 CCND1 MYC TP53
24
Apoptosis and survival Caspase cascade 22
Show member pathways
 12.3 AKT1 CASP3 MAPK9 PSMB9
25
G-protein signaling Ras family GTPases in kinase cascades (scheme) 22
Show member pathways
 12.29 AKT1 CASP3 MAPK9 TP53
26
p53 Signaling 64
Show member pathways
 12.28 AKT1 CASP3 CCND1 MAPK9 TP53
27
Epstein-Barr virus infection 37
12.28 AKT1 CASP3 CCND1 MAPK9 MYC TP53
28
Cell cycle Role of SCF complex in cell cycle regulation 22
Show member pathways
 12.27 CCND1 CDKN2A MAPK9 MYC
29
MAPK Signaling: Mitogen Stimulation Pathway 65
Show member pathways
 12.25 AKT1 CASP3 CCND1 MYC TP53
30
Cellular senescence (KEGG) 37
12.2 AKT1 CCND1 CDKN2A MYC TP53
31
AKT Signaling Pathway 67
12.18 AKT1 CASP3 CCND1 MYC TP53
32
NGF Pathway 64
Show member pathways
 12.17 AKT1 CASP3 MAPK9 MYC TP53
33
SMAD Signaling Network 64
12.1 CDKN2A MAPK9 PSMB9 TP53
34
UVA-Induced MAPK Signaling 64
Show member pathways
 12.1 AKT1 CASP3 MAPK9 TP53
35
WNT Signaling 64
12.1 AKT1 CCND1 CDH1 MAPK9 MYC PSMB9
36
TGF-beta Signaling Pathway (WikiPathways) 1
12.09 AKT1 CCND1 MAPK9 MYC TP53
37
Spinal Cord Injury 1
12.07 CASP3 CCND1 MYC TP53
38
Thyroid hormone signaling pathway 37
12.05 AKT1 CCND1 MYC TP53
39
Interleukin-4 and 13 signaling 66
12.03 AKT1 CCND1 MYC TP53
40
Colorectal Cancer Metastasis 64
12.02 AKT1 CASP3 CCND1 CDH1 MYC TP53
41
Glioblastoma Multiforme 64
11.97 AKT1 CCND1 CDKN2A MYC TP53
42
AGE-RAGE signaling pathway in diabetic complications 37
11.95 AKT1 CASP3 CCND1 MAPK9
43
Cell cycle Cell cycle (generic schema) 22
Show member pathways
 11.93 AKT1 CCND1 CDH1 MAPK9 MYC PSMB9
44
Integrated Breast Cancer Pathway 1
11.92 AKT1 CASP3 CCND1 CDH1 MYC TP53
45
TGF-beta Signaling Pathways 65
11.91 AKT1 MAPK9 MYC
46
Corticotropin-releasing hormone signaling pathway 1
11.9 AKT1 CASP3 MAPK9
47
Small cell lung cancer 37
11.88 AKT1 CASP3 CCND1 MYC TP53
48
Retinoblastoma (RB) in Cancer 1
11.87 CCND1 MYC TP53
49
LT-BetaR Pathway 64
Show member pathways
 11.84 AKT1 CASP3 MAPK9
50
Glucocorticoid receptor regulatory network 1
11.84 AKT1 MAPK9 TP53
Sources

GO Terms for Nasopharyngeal Disease

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Cellular components related to Nasopharyngeal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.8 AKT1 ARL2BP BRD7 CASP3 CCND1 CDKN2A
2 nucleoplasm GO:0005654 9.36 AKT1 BRD7 CASP3 CCND1 CDKN2A CFAP45

Biological processes related to Nasopharyngeal Disease according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.85 AKT1 CDKN2A MAPK9 MYC TP53
2 positive regulation of transcription, DNA-templated GO:0045893 9.85 AKT1 BRD7 CDH1 CDKN2A MYC TP53
3 positive regulation of apoptotic process GO:0043065 9.8 AKT1 CASP3 CDKN2A MAPK9 TP53
4 G1/S transition of mitotic cell cycle GO:0000082 9.72 CCND1 CDKN2A MYC
5 regulation of signal transduction by p53 class mediator GO:1901796 9.69 AKT1 BRD7 TP53
6 cellular response to organic cyclic compound GO:0071407 9.67 AKT1 CASP3 MYC
7 striated muscle cell differentiation GO:0051146 9.56 AKT1 CASP3
8 cytokine-mediated signaling pathway GO:0019221 9.55 AKT1 CASP3 CCND1 MYC TP53
9 replicative senescence GO:0090399 9.54 CDKN2A TP53
10 positive regulation of mitochondrial membrane potential GO:0010918 9.52 AKT1 MYC
11 cellular response to organic substance GO:0071310 9.5 CASP3 CCND1 MAPK9
12 mitotic G1 DNA damage checkpoint GO:0031571 9.48 CCND1 TP53
13 re-entry into mitotic cell cycle GO:0000320 9.43 CCND1 MYC
14 cellular response to DNA damage stimulus GO:0006974 9.43 AKT1 CASP3 CCND1 MYC SMUG1 TP53
15 response to UV-A GO:0070141 9.26 AKT1 CCND1
16 response to organic substance GO:0010033 8.92 AKT1 CASP3 CCND1 CDH1

Molecular functions related to Nasopharyngeal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 GTPase activating protein binding GO:0032794 9.16 AKT1 CDH1
2 transcription factor binding GO:0008134 9.1 BRD7 CCND1 CDKN2A MAPK9 MYC TP53
3 cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0004861 8.96 CASP3 CDKN2A
Sources

Sources for Nasopharyngeal Disease

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
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46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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