MCID: NSP002
MIFTS: 43

Nasopharyngitis

Categories: Oral diseases, Respiratory diseases

Aliases & Classifications for Nasopharyngitis

Summaries for Nasopharyngitis

Disease Ontology : 12 A nasopharyngeal disease which involves inflammation of the nasal passages and upper part of the pharynx.

MalaCards based summary : Nasopharyngitis, also known as chronic nasopharyngitis, is related to candidiasis and nasopharyngeal carcinoma. An important gene associated with Nasopharyngitis is DPP4 (Dipeptidyl Peptidase 4), and among its related pathways/superpathways are Cytokine Signaling in Immune system and IL-17 Family Signaling Pathways. The drugs Pioglitazone and Metformin have been mentioned in the context of this disorder. Affiliated tissues include pituitary, tongue and bone, and related phenotypes are craniofacial and digestive/alimentary

Wikipedia : 77 The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory... more...

Related Diseases for Nasopharyngitis

Diseases related to Nasopharyngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 469)
# Related Disease Score Top Affiliating Genes
1 candidiasis 29.2 IL17A IL17F IL17RA
2 nasopharyngeal carcinoma 12.8
3 nasopharyngeal carcinoma 3 12.6
4 juvenile nasopharyngeal angiofibroma 12.5
5 nasopharyngeal carcinoma 2 12.4
6 nasopharyngeal disease 12.3
7 nasopharyngeal teratoma 12.2
8 dandy-walker malformation with nasopharyngeal teratoma and diaphragmatic hernia 12.1
9 nasopharyngeal cancer, childhood 12.0
10 lymphoepithelioma-like carcinoma 11.9
11 common cold 11.8
12 pharyngitis 11.7
13 otosalpingitis 11.4
14 diphtheria 10.6
15 chronic rhinitis 10.5
16 haemophilus influenzae 10.5
17 otitis media 10.5
18 lymphoma 10.5
19 teratoma 10.5
20 fibroma 10.3
21 bronchiolitis 10.3
22 burkitt lymphoma 10.3
23 adenocarcinoma 10.3
24 hypoxia 10.3
25 papillary adenocarcinoma 10.2
26 dermatomyositis 10.2
27 pertussis 10.2
28 squamous cell carcinoma 10.2
29 adenoma 10.2
30 cleft palate, isolated 10.2
31 mucositis 10.2
32 pneumonia 10.2
33 stromal keratitis 10.2 IL17A IL17RA
34 chordoma 10.2
35 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
36 papilloma 10.2
37 opportunistic mycosis 10.1 IL17A IL17RA
38 pfeiffer syndrome 10.1
39 sinusitis 10.1
40 sleep apnea 10.1
41 squamous cell papilloma 10.1
42 isolated pierre robin sequence 10.1
43 acute generalized exanthematous pustulosis 10.1 IL17A IL17F
44 adenoid cystic carcinoma 10.1
45 sensorineural hearing loss 10.1
46 hypothyroidism 10.1
47 panuveitis 10.1 IL17A TNFRSF1B
48 familial candidiasis 10.1 IL17F IL17RA
49 pierre robin syndrome 10.1
50 sarcoma 10.1

Graphical network of the top 20 diseases related to Nasopharyngitis:



Diseases related to Nasopharyngitis

Symptoms & Phenotypes for Nasopharyngitis

MGI Mouse Phenotypes related to Nasopharyngitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.35 DHRS3 EDAR IL17A IL17F TNFRSF1B
2 digestive/alimentary MP:0005381 9.02 DHRS3 EDAR IL17A IL17F TNFRSF1B

Drugs & Therapeutics for Nasopharyngitis

Drugs for Nasopharyngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 51)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
2
Metformin Approved Phase 4 657-24-9 14219 4091
3
Mirabegron Approved Phase 4 223673-61-8 9865528
4
Glycine Approved, Nutraceutical, Vet_approved Phase 4 56-40-6 750
5
protease inhibitors Phase 4
6 Hormones Phase 4,Phase 2
7 Sitagliptin Phosphate Phase 4
8 Hormone Antagonists Phase 4
9 Dipeptidyl-Peptidase IV Inhibitors Phase 4
10 HIV Protease Inhibitors Phase 4
11 Incretins Phase 4
12 Hypoglycemic Agents Phase 4
13 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
14 Adrenergic Agonists Phase 4
15 Solifenacin succinate Phase 4 242478-38-2
16 Neurotransmitter Agents Phase 4
17 Adrenergic beta-3 Receptor Agonists Phase 4
18 Muscarinic Antagonists Phase 4
19 Adrenergic Agents Phase 4
20 Cholinergic Antagonists Phase 4
21 Cholinergic Agents Phase 4
22 Adrenergic beta-Agonists Phase 4
23 Immunologic Factors Phase 4,Phase 2
24 Vaccines Phase 4,Phase 2
25
Tocopherol Approved, Investigational Phase 3 1406-66-2 14986
26
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
27
Coenzyme Q10 Approved, Investigational, Nutraceutical Phase 3 303-98-0 5281915
28 Tocotrienol Investigational Phase 3 6829-55-6
29 Protective Agents Phase 3
30 Tocopherols Phase 3
31 Vitamins Phase 3
32 Antioxidants Phase 3
33 Trace Elements Phase 3
34 Tocotrienols Phase 3
35 Nutrients Phase 3
36 Micronutrients Phase 3
37 Ubiquinone Phase 3
38
Vancomycin Approved Phase 2 1404-90-6 14969 441141
39
Isradipine Approved, Investigational Phase 2 75695-93-1 3784
40
Calcium Approved, Nutraceutical Phase 2 7440-70-2 271
41 Anti-Infective Agents Phase 2,Not Applicable
42 Pharmaceutical Solutions Phase 2
43 Cola Phase 2
44 Anti-Bacterial Agents Phase 2,Not Applicable
45 Calcium, Dietary Phase 2
46 Antihypertensive Agents Phase 2
47 Vasodilator Agents Phase 2
48 calcium channel blockers Phase 2
49 Antibiotics, Antitubercular Not Applicable
50 Antitubercular Agents Not Applicable

Interventional clinical trials:

(show all 20)
# Name Status NCT ID Phase Drugs
1 Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea Completed NCT01195090 Phase 4 Sitagliptin;pioglitazone
2 Efficacy and Safety of the Mirabegron Compared With Solifenacin in Treatment of Overactive Bladder Completed NCT03558919 Phase 4 Mirabegron 25mg;Solifenacin Succinate 5 MG
3 Non-specific Effects of Rabies Vaccine Enrolling by invitation NCT03656198 Phase 4 Sterile Water Injection
4 A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis From France Who Completed WA19977 Core Study Completed NCT01673919 Phase 3 tocilizumab [RoActemra/Actemra]
5 E. Coli Nissle 1917 - Suspension for Infection Prophylaxis Active, not recruiting NCT02802059 Phase 3 EcN-Suspension;Placebo
6 Effects of Coenzyme Q10 (CoQ) in Parkinson Disease Terminated NCT00740714 Phase 3 Coenzyme Q10 with vitamin E;placebo with vitamin E
7 Effect of Fecal Microbiota Transplantation in Slow Transit Constipation Unknown status NCT02301221 Phase 2 Vancomycin and bowel lavage
8 Evaluating the Synergism of Soluble Dietary Fiber With Fecal Microbiota Transplantation in Slow Transit Constipation Unknown status NCT02291354 Phase 2 Pectin
9 Freeze-dried vs Fresh Fecal Microbiota Transplantation in Patients With Slow Transit Constipation Unknown status NCT02676388 Phase 2
10 Efficacy and Safety of Fecal Microbiota Transplantation for Slow Transit Constipation Unknown status NCT02526849 Phase 2 Fecal microbiota transplantation (FMT)
11 Safety, Tolerability and Efficacy Assessment of Dynacirc CR in Parkinson Disease Completed NCT00909545 Phase 2 Isradipine CR 5mg;Isradipine CR 10mg;Isradipine CR 20mg;Placebo
12 Safety, Reactogenicity and Immunogenicity of Vi-DT;Typhoid Conjugate Vaccine Active, not recruiting NCT03527355 Phase 2
13 Experience of Mutaflor Suspension Use in Preterm Infants for Immunity Improvement Completed NCT01540162
14 Impact of Handing to Patients a Copy of the Consultation Report on Their Medicine Consumption Completed NCT02237573 Not Applicable
15 Nudging Guideline-concordant Antibiotic Prescribing Using Public Commitments Completed NCT01767064 Not Applicable
16 Use of Behavioral Economics to Improve Treatment of Acute Respiratory Infections (Main Study) Completed NCT01454947 Not Applicable
17 Use of Behavioral Economics to Improve Treatment of Acute Respiratory Infections (Pilot Study) Completed NCT01454960 Not Applicable
18 A Post Marketing Evaluation of the Effectiveness of FluMist Risk Minimization Plan in Children Completed NCT00626808 No Intervention
19 Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers Completed NCT01033799 Not Applicable
20 Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation Terminated NCT01315418 Not Applicable

Search NIH Clinical Center for Nasopharyngitis

Cochrane evidence based reviews: nasopharyngitis

Genetic Tests for Nasopharyngitis

Anatomical Context for Nasopharyngitis

MalaCards organs/tissues related to Nasopharyngitis:

42
Pituitary, Tongue, Bone, Prostate, Tonsil, Kidney, Myeloid

Publications for Nasopharyngitis

Articles related to Nasopharyngitis:

(show all 35)
# Title Authors Year
1
Isolated septic non-otogenic lateral sinus thrombosis complicating nasopharyngitis in a 2-month-old infant: a case report. ( 30363232 )
2017
2
Treatment of chronic nasopharyngitis with monopolar suction diathermy. ( 19825225 )
2010
3
Antibiotics for nasopharyngitis are associated with a lower risk of office-based physician visit for acute otitis media within 14 days for 3- to 6-year-old children. ( 19126177 )
2008
4
Re: Nasopharyngitis is a clinical sign of laryngopharyngeal reflux. ( 17283577 )
2007
5
Is acetaminophen as effective as an antihistamine-decongestant-acetaminophen combination in relieving symptoms of acute nasopharyngitis in children? A randomised, controlled trial. ( 17560664 )
2007
6
The burden of acute nasopharyngitis among adolescents. ( 17119096 )
2006
7
Antibiotic prescribing for children with nasopharyngitis (common colds), upper respiratory infections, and bronchitis who have health-professional parents. ( 16199689 )
2005
8
Antibiotic prescribing by ambulatory care physicians for adults with nasopharyngitis, URIs, and acute bronchitis in Taiwan: a multi-level modeling approach. ( 15722399 )
2005
9
Microbial dynamics of purulent nasopharyngitis in children. ( 14550957 )
2003
10
Dynamics of nasopharyngitis in children. ( 10793349 )
2000
11
Acute nasopharyngitis in adults: an independent clinical entity? ( 11115528 )
2000
12
An international medico-economic survey of 2007 children with recurrent nasopharyngitis and acute otitis media. Preliminary bindings. ( 9378078 )
1997
13
Adult bacterial nasopharyngitis: a clinical entity? ( 8120682 )
1993
14
Aerobic and anaerobic bacteriology of purulent nasopharyngitis in children. ( 3356794 )
1988
15
Choanal bleeding due to nasopharyngitis. ( 3593129 )
1986
16
Bacteriology and treatment of purulent nasopharyngitis: a double blind, placebo-controlled evaluation. ( 6377256 )
1984
17
Apnea and sleep state in infants with nasopharyngitis. ( 7367076 )
1980
18
Experimental nasopharyngitis and pneumonia caused by Chlamydia trachomatis in infant baboons: histopathologic comparison with a case in a human infant. ( 108341 )
1979
19
A new approach to the treatment of allergic nasopharyngitis. ( 900584 )
1977
20
Nasopharyngitis and the sudden infant death syndrome. ( 905017 )
1977
21
Nasopharyngitis. ( 1062917 )
1975
22
Nasopharyngitis and prolonged sleep Apnea. ( 1196764 )
1975
23
Asthma and nasopharyngitis. ( 4283488 )
1974
24
Headache with particular relationship to nasopharyngitis. ( 4516525 )
1973
25
A clinical and experimental study of the nasopharyngeal flora in nasopharyngitis. ( 5273195 )
1970
26
Relation between autonomic nerve symptons and the finger vasomotor reflex in nasopharyngitis. ( 5249566 )
1968
27
CLINICAL, BACTERIOLOGICAL AND SEROLOGICAL STUDIES ON CHRONIC ATROPHIC NONFETID NASOPHARYNGITIS AND LARYNGITIS. ( 14247373 )
1964
28
CLINICAL, BACTERIOLOGICAL AND SEROLOGICAL STUDIES ON CHRONIC ATROPHIC FETID NASOPHARYNGITIS. ( 14247372 )
1964
29
Vitamin A therapy in atrophic nasopharyngitis and rhinitis. ( 13369821 )
1956
30
Membranous cryptococcic nasopharyngitis (Cryptococcus neoformans). ( 13206533 )
1954
31
Acute nasopharyngitis. ( 18920984 )
1948
32
Myocarditis associated with acute nasopharyngitis and acute tonsillitis. ( 20271991 )
1947
33
Sulfadiazine and penicillin for hemolytic streptococcus infections of the upper respiratory tract; an evaluation in tonsillitis, nasopharyngitis and scarlet fever. ( 21025322 )
1946
34
The diagnosis of haemolytic streptococcal infection in acute nasopharyngitis. ( 21027302 )
1946
35
Sulfadiazine Prophylaxis in Nasopharyngitis and Scarlet Fever. ( 20323191 )
1944

Variations for Nasopharyngitis

Expression for Nasopharyngitis

Search GEO for disease gene expression data for Nasopharyngitis.

Pathways for Nasopharyngitis

GO Terms for Nasopharyngitis

Cellular components related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.23 CPA6 DPP4 IL17A IL17F IL17RA LTF

Biological processes related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.76 CPA6 DPP4 LTF PCSK9
2 apoptotic process GO:0006915 9.73 EDAR IL17A PCSK9 TNFRSF1B
3 cytokine-mediated signaling pathway GO:0019221 9.65 IL17A IL17F TNFRSF1B
4 bone morphogenesis GO:0060349 9.4 DHRS3 LTF
5 defense response to fungus GO:0050832 9.37 IL17A IL17RA
6 positive regulation of interleukin-6 secretion GO:2000778 9.32 IL17A IL17F
7 positive regulation of interleukin-23 production GO:0032747 9.26 IL17A IL17RA
8 fibroblast activation GO:0072537 9.16 IL17A IL17RA
9 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.13 IL17A IL17F IL17RA
10 interleukin-17-mediated signaling pathway GO:0097400 8.8 IL17A IL17F IL17RA

Molecular functions related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.33 DPP4 LTF PCSK9
2 peptidase activity GO:0008233 9.26 CPA6 DPP4 LTF PCSK9
3 serine-type peptidase activity GO:0008236 8.8 DPP4 LTF PCSK9

Sources for Nasopharyngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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