MCID: NSP002
MIFTS: 46

Nasopharyngitis

Categories: Respiratory diseases

Aliases & Classifications for Nasopharyngitis

MalaCards integrated aliases for Nasopharyngitis:

Name: Nasopharyngitis 12 76 55 44 15 73
Chronic Nasopharyngitis 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10460
ICD10 33 J00 J31.1
ICD9CM 35 472.2
MeSH 44 D009304
NCIt 50 C34837

Summaries for Nasopharyngitis

Disease Ontology : 12 A nasopharyngeal disease which involves inflammation of the nasal passages and upper part of the pharynx.

MalaCards based summary : Nasopharyngitis, also known as chronic nasopharyngitis, is related to nasopharyngeal disease and nasopharyngeal carcinoma. An important gene associated with Nasopharyngitis is DPP4 (Dipeptidyl Peptidase 4), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Cytokine production by Th17 cells in CF (Mouse model). The drugs Metformin and Pioglitazone have been mentioned in the context of this disorder. Affiliated tissues include lymph node, endothelial and t cells.

Wikipedia : 76 The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory... more...

Related Diseases for Nasopharyngitis

Diseases related to Nasopharyngitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 275)
# Related Disease Score Top Affiliating Genes
1 nasopharyngeal disease 26.5 ARL2BP DHRS3 DPP4 IL17A IL17F IL17RA
2 nasopharyngeal carcinoma 12.6
3 nasopharyngeal carcinoma 3 12.3
4 nasopharyngeal carcinoma 2 12.2
5 juvenile nasopharyngeal angiofibroma 12.1
6 nasopharyngeal teratoma 12.0
7 dandy-walker malformation with nasopharyngeal teratoma and diaphragmatic hernia 11.9
8 nasopharyngeal cancer, childhood 11.8
9 lymphoepithelioma-like carcinoma 11.7
10 common cold 11.6
11 pharyngitis 11.5
12 otosalpingitis 11.2
13 teratoma 10.4
14 chronic rhinitis 10.4
15 stromal keratitis 10.2 IL17A IL17RA
16 endotheliitis 10.2
17 otitis media 10.2
18 lymphoma 10.2
19 adenocarcinoma 10.2
20 papillary adenocarcinoma 10.1
21 hypoxia 10.1
22 opportunistic mycosis 10.1 IL17A IL17RA
23 pneumonia 10.0
24 esophagitis 10.0
25 adenoma 10.0
26 cervicitis 10.0
27 thyroiditis 10.0
28 influenza 10.0
29 bronchiolitis 10.0
30 squamous cell carcinoma 10.0
31 aging 10.0
32 adenoiditis 10.0
33 pierre robin syndrome 9.9
34 mucositis 9.9
35 haemophilus influenzae 9.9
36 isolated pierre robin sequence 9.9
37 diphtheria 9.9
38 cleft palate, isolated 9.9
39 sinusitis 9.9
40 dermatomyositis 9.9
41 tonsillitis 9.9
42 laryngitis 9.9
43 sleep apnea 9.9
44 papilloma 9.9
45 cranial nerve palsy 9.9
46 rhinitis 9.9
47 pleomorphic adenoma 9.9
48 apnea, obstructive sleep 9.9
49 paraganglioma 9.9
50 pertussis 9.9

Graphical network of the top 20 diseases related to Nasopharyngitis:



Diseases related to Nasopharyngitis

Symptoms & Phenotypes for Nasopharyngitis

Drugs & Therapeutics for Nasopharyngitis

Drugs for Nasopharyngitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 40)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 14219 4091
2
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
3 Dipeptidyl-Peptidase IV Inhibitors Phase 4
4 HIV Protease Inhibitors Phase 4
5 Hormone Antagonists Phase 4
6 Hormones Phase 4
7 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
8 Hypoglycemic Agents Phase 4
9 Incretins Phase 4
10
protease inhibitors Phase 4
11 Sitagliptin Phosphate Phase 4
12
Coenzyme Q10 Approved, Investigational, Nutraceutical Phase 3 303-98-0 5281915
13
Tocopherol Approved, Investigational, Nutraceutical Phase 3 1406-66-2 14986
14
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
15 Antioxidants Phase 3
16 Micronutrients Phase 3
17 Protective Agents Phase 3
18 Tocopherols Phase 3
19 Tocotrienols Phase 3
20 Trace Elements Phase 3
21 Ubiquinone Phase 3
22 Vitamins Phase 3
23 Tocotrienol Investigational, Nutraceutical Phase 3 6829-55-6
24
Loperamide Approved Phase 2 53179-11-6 3955
25
Pectin Approved, Investigational, Vet_approved Phase 2 9000-69-5 441476
26
Isradipine Approved, Investigational Phase 2 75695-93-1 3784
27
Vancomycin Approved Phase 2 1404-90-6 441141 14969
28 Antidiarrheals Phase 2
29 Gastrointestinal Agents Phase 2
30 Antihypertensive Agents Phase 2
31 calcium channel blockers Phase 2
32 Calcium, Dietary Phase 2
33 Vasodilator Agents Phase 2
34 Anti-Bacterial Agents Phase 2,Not Applicable
35 Anti-Infective Agents Phase 2,Not Applicable
36 Pharmaceutical Solutions Phase 2
37 Cola Nutraceutical Phase 2
38 Antibiotics, Antitubercular Not Applicable
39 Antitubercular Agents Not Applicable
40 Acidophilus Nutraceutical Not Applicable

Interventional clinical trials:

(show all 19)
# Name Status NCT ID Phase Drugs
1 Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea Completed NCT01195090 Phase 4 Sitagliptin;pioglitazone
2 Efficacy and Safety of the Mirabegron Compared With Solifenacin in Treatment of Overactive Bladder Completed NCT03558919 Phase 4 Mirabegron 25mg;Solifenacin Succinate 5 MG
3 A Long-Term Extension Study of RoActemra/Actemra (Tocilizumab) in Patients With Juvenile Idiopathic Arthritis From France Who Completed WA19977 Core Study Completed NCT01673919 Phase 3 tocilizumab [RoActemra/Actemra]
4 E. Coli Nissle 1917 - Suspension for Infection Prophylaxis Recruiting NCT02802059 Phase 3 EcN-Suspension;Placebo
5 Effects of Coenzyme Q10 (CoQ) in Parkinson Disease Terminated NCT00740714 Phase 3 Coenzyme Q10 with vitamin E;placebo with vitamin E
6 Evaluating the Synergism of Soluble Dietary Fiber With Fecal Microbiota Transplantation in Slow Transit Constipation Unknown status NCT02291354 Phase 2 Pectin
7 Freeze-dried vs Fresh Fecal Microbiota Transplantation in Patients With Slow Transit Constipation Unknown status NCT02676388 Phase 2
8 Safety, Tolerability and Efficacy Assessment of Dynacirc CR in Parkinson Disease Completed NCT00909545 Phase 2 Isradipine CR 5mg;Isradipine CR 10mg;Isradipine CR 20mg;Placebo
9 Safety, Reactogenicity and Immunogenicity of Vi-DT;Typhoid Conjugate Vaccine Recruiting NCT03527355 Phase 2
10 Efficacy and Safety of Fecal Microbiota Transplantation for Slow Transit Constipation Recruiting NCT02526849 Phase 2 Fecal microbiota transplantation (FMT)
11 Effect of Fecal Microbiota Transplantation in Slow Transit Constipation Active, not recruiting NCT02301221 Phase 2 Vancomycin and bowel lavage
12 Experience of Mutaflor Suspension Use in Preterm Infants for Immunity Improvement Completed NCT01540162
13 Impact of Handing to Patients a Copy of the Consultation Report on Their Medicine Consumption Completed NCT02237573 Not Applicable
14 Nudging Guideline-concordant Antibiotic Prescribing Using Public Commitments Completed NCT01767064 Not Applicable
15 Use of Behavioral Economics to Improve Treatment of Acute Respiratory Infections (Main Study) Completed NCT01454947 Not Applicable
16 Use of Behavioral Economics to Improve Treatment of Acute Respiratory Infections (Pilot Study) Completed NCT01454960 Not Applicable
17 A Post Marketing Evaluation of the Effectiveness of FluMist Risk Minimization Plan in Children Completed NCT00626808 No Intervention
18 Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers Completed NCT01033799 Not Applicable
19 Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation Terminated NCT01315418 Not Applicable

Search NIH Clinical Center for Nasopharyngitis

Cochrane evidence based reviews: nasopharyngitis

Genetic Tests for Nasopharyngitis

Anatomical Context for Nasopharyngitis

MalaCards organs/tissues related to Nasopharyngitis:

41
Lymph Node, Endothelial, T Cells, Thyroid, Pituitary, Bone, Tonsil

Publications for Nasopharyngitis

Articles related to Nasopharyngitis:

(show top 50) (show all 3229)
# Title Authors Year
1
Localised nasopharyngeal amyloidosis: the importance of postoperative follow-up. ( 29444790 )
2018
2
Dosimetric Comparisons of Volumetric Modulated Arc Therapy and Tomotherapy for Early T-Stage Nasopharyngeal Carcinoma. ( 29967769 )
2018
3
A study on the value of narrow-band imaging (NBI) for the general investigation of a high-risk population of nasopharyngeal carcinoma (NPC). ( 29973209 )
2018
4
Facial Palsy Following Embolization of a Juvenile Nasopharyngeal Angiofibroma. ( 29488393 )
2018
5
Differential Gene Expression and Pathway Analysis in Juvenile Nasopharyngeal Angiofibroma Using RNA Sequencing. ( 29634432 )
2018
6
A Case of Neurotrophic Keratopathy Associated with Nasopharyngeal Carcinoma. ( 29643792 )
2018
7
Optimal cumulative cisplatin dose in nasopharyngeal carcinoma patients receiving additional induction chemotherapy. ( 29266526 )
2018
8
Long non-coding RNA n326322 promotes the proliferation and invasion in nasopharyngeal carcinoma. ( 29416735 )
2018
9
Long non-coding RNA FOXD2-AS1 aggravates nasopharyngeal carcinoma carcinogenesis by modulating miR-363-5p/S100A1 pathway. ( 29248577 )
2018
10
Reduced QSOX1 enhances radioresistance in nasopharyngeal carcinoma. ( 29423042 )
2018
11
Lack of association between the distribution of ABO blood groups and nasopharyngeal carcinoma in a population of Southern China. ( 29970653 )
2018
12
Assisted resection of lateral extension of juvenile nasopharyngeal angiofibroma using a sphenopalatine fossa dissector. ( 29909791 )
2018
13
miR-93 enhances cell proliferation by directly targeting CDKN1A in nasopharyngeal carcinoma. ( 29434867 )
2018
14
Evaluation of circulating EBV microRNA BART2-5p in facilitating early detection and screening of nasopharyngeal carcinoma. ( 29971780 )
2018
15
High COX-2 expression contributes to a poor prognosis through the inhibition of chemotherapy-induced senescence in nasopharyngeal carcinoma. ( 29956730 )
2018
16
Time course and clinical characterization of cisplatin-induced ototoxicity after treatment for nasopharyngeal carcinoma in a South East Asian population. ( 29451951 )
2018
17
Randomized, Double-Blind, Placebo-Controlled Trial of Shuanghua Baihe Tablets to Prevent Oral Mucositis in Patients With Nasopharyngeal Cancer Undergoing Chemoradiation Therapy. ( 29353657 )
2018
18
Downregulation of ribophorin II suppresses tumor growth, migration, and invasion of nasopharyngeal carcinoma. ( 29942140 )
2018
19
Development and validation of a gene expression-based signature to predict distant metastasis in locoregionally advanced nasopharyngeal carcinoma: a retrospective, multicentre, cohort study. ( 29428165 )
2018
20
A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response. ( 29956500 )
2018
21
Juvenile Nasopharyngeal Angiofibroma With Sphenoid Sinus Invasion and Protrusion: Treatment Approach With Le Fort I Osteotomy. ( 29481518 )
2018
22
Promoter hypermethylation of SLIT2 is a risk factor and potential diagnostic biomarker for nasopharyngeal carcinoma. ( 29107007 )
2018
23
LncRNA THOR attenuates cisplatin sensitivity of nasopharyngeal carcinoma cells via enhancing cells stemness. ( 29959065 )
2018
24
Orbital, eyelid, and nasopharyngeal silicone oil granuloma presenting as ptosis & pseudo-xanthelasma. ( 29978139 )
2018
25
Nasopharyngeal rhinosporidiosis with intracranial extension masquerading as juvenile angiofibroma: an unusual entity. ( 29745260 )
2018
26
Endoscopic Surgery for Delayed Sinonasal Complications of Radiation Therapy for Nasopharyngeal Carcinoma: A Subjective Outcome. ( 29439883 )
2018
27
Cumulative sum analysis of the learning curve for endoscopic resection of juvenile nasopharyngeal angiofibroma. ( 29368283 )
2018
28
Hypoxia-Inducible Factor-1I+ (HIF-1I+) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis. ( 29717655 )
2018
29
LncRNA-LINC00460 facilitates nasopharyngeal carcinoma tumorigenesis through sponging miR-149-5p to up-regulate IL6. ( 28987345 )
2018
30
Endonasal endoscopic nasopharyngectomy for the treatment of nasopharyngeal papillary adenocarcinoma: Report of a rare case. ( 29287881 )
2018
31
Nasopharyngeal Papillary Adenocarcinoma as a Second Head and Neck Malignancy. ( 29923095 )
2018
32
Stable knockdown of ZBTB7A promotes cell proliferation and progression in nasopharyngeal carcinoma. ( 29699474 )
2018
33
Juvenile Nasopharyngeal Angiofibroma: Combined Approach for Excision, Transpalatal and Endoscopic; A New Perspective. ( 29456956 )
2018
34
Induction chemotherapy plus concurrent chemoradiotherapy in endemic nasopharyngeal carcinoma: individual patient data pooled analysis of four randomized trials. ( 29431618 )
2018
35
Using the nasoseptal flap for reconstruction after endoscopic debridement of radionecrosis in nasopharyngeal carcinoma. ( 29336293 )
2018
36
Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma. ( 29413277 )
2018
37
Retraction Note to: Differences in the expression profiles of claudin proteins in human nasopharyngeal carcinoma compared with non-neoplastic mucosa. ( 29940962 )
2018
38
MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition. ( 29427737 )
2018
39
Activation of SREBP1-mediated lipogenesis by the Epstein-Barr Virus-encoded LMP1 promotes cell proliferation and progression of nasopharyngeal carcinoma. ( 29968360 )
2018
40
Prevalent somatic BRCA1 mutations shape clinically relevant genomic patterns of nasopharyngeal carcinoma in Southeast Europe. ( 28857155 )
2018
41
Predictive value of excision repair cross- complementation group 1 expression in locoregionally advanced nasopharyngeal carcinoma receiving cisplatin-based concurrent chemoradiotherapy. ( 29439312 )
2018
42
Long-Term Use of Nimotuzumab in Combination With Intensity-Modulated Radiotherapy and Chemotherapy in the Treatment of Locoregionally Advanced Nasopharyngeal Carcinoma: Experience of a Single Institution. ( 29046165 )
2018
43
Elevated antibodies against Epstein-Barr virus among individuals predicted to carry nasopharyngeal carcinoma susceptibility variants. ( 29975184 )
2018
44
Diffusion kurtosis imaging of a human nasopharyngeal carcinoma xenograft model: Initial experience with pathological correlation. ( 29221965 )
2018
45
Endoscopic endonasal transmaxillary ligation of a feeding artery and coblation plasma technology enables en bloc resection of advanced juvenile nasopharyngeal angiofibroma without preoperative embolization. ( 29980404 )
2018
46
The diagnosis and management of rare cystic liver metastases from nasopharyngeal carcinoma: A case report. ( 29952994 )
2018
47
Clinicopathologic Characteristics of Thyroid-like Low-grade Nasopharyngeal Papillary Adenocarcinoma: A Case Report. ( 29494399 )
2018
48
Vimentin is a crucial target for anti-metastasis therapy of nasopharyngeal carcinoma. ( 28744809 )
2018
49
Efficacy and Safety of Nimotuzumab Plus Radiotherapy With or Without Cisplatin-Based Chemotherapy in an Elderly Patient Subgroup (Aged 60 and Older) With Nasopharyngeal Carcinoma. ( 29425953 )
2018
50
Functions and Roles of Long-Non-Coding RNAs in Human Nasopharyngeal Carcinoma. ( 29448252 )
2018

Variations for Nasopharyngitis

Expression for Nasopharyngitis

Search GEO for disease gene expression data for Nasopharyngitis.

Pathways for Nasopharyngitis

Pathways related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.46 IL17A IL17F IL17RA
2
Show member pathways
10.77 IL17A IL17F IL17RA

GO Terms for Nasopharyngitis

Cellular components related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.87 DPP4 IL17A IL17F IL17RA IL36RN LTF
2 spindle GO:0005819 9.61 ARL2BP SEPT12 SEPT6
3 midbody GO:0030496 9.54 ARL2BP SEPT12 SEPT6
4 cleavage furrow GO:0032154 9.46 SEPT12 SEPT6
5 cell division site GO:0032153 9.4 SEPT12 SEPT6
6 septin filament array GO:0032160 9.26 SEPT12 SEPT6
7 septin complex GO:0031105 9.16 SEPT12 SEPT6
8 septin ring GO:0005940 8.96 SEPT12 SEPT6
9 sperm annulus GO:0097227 8.62 SEPT12 SEPT6

Biological processes related to Nasopharyngitis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.73 IL17A IL17F IL36RN PCSK9
2 cytokine-mediated signaling pathway GO:0019221 9.67 IL17A IL17F IL36RN LRRC4
3 mitotic cytokinesis GO:0000281 9.52 SEPT12 SEPT6
4 cellular protein localization GO:0034613 9.51 SEPT12 SEPT6
5 bone morphogenesis GO:0060349 9.49 DHRS3 LTF
6 defense response to fungus GO:0050832 9.48 IL17A IL17RA
7 positive regulation of interleukin-6 secretion GO:2000778 9.46 IL17A IL17F
8 septin ring assembly GO:0000921 9.4 SEPT12 SEPT6
9 positive regulation of interleukin-23 production GO:0032747 9.32 IL17A IL17RA
10 antifungal humoral response GO:0019732 9.26 IL36RN LTF
11 fibroblast activation GO:0072537 9.16 IL17A IL17RA
12 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.13 IL17A IL17F IL17RA
13 interleukin-17-mediated signaling pathway GO:0097400 8.8 IL17A IL17F IL17RA

Molecular functions related to Nasopharyngitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase activity GO:0004252 9.33 DPP4 LTF PCSK9
2 protein-containing complex scaffold activity GO:0032947 9.26 SEPT12 SEPT6
3 cytokine activity GO:0005125 9.13 IL17A IL17F IL36RN
4 serine-type peptidase activity GO:0008236 8.8 DPP4 LTF PCSK9

Sources for Nasopharyngitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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