ANUG
MCID: NCR001
MIFTS: 26

Necrotizing Ulcerative Gingivitis (ANUG)

Categories: Oral diseases, Rare diseases

Aliases & Classifications for Necrotizing Ulcerative Gingivitis

MalaCards integrated aliases for Necrotizing Ulcerative Gingivitis:

Name: Necrotizing Ulcerative Gingivitis 12 15 17 70
Acute Necrotizing Ulcerative Gingivitis 12 73 20
Vincent's Disease 12 70
Vincent Angina 12 70
Anug 12 20
Acute Necrotising Ulcerative Gingivostomatitis 12
Acute Necrotizing Ulcerative Gingivostomatitis 12
Acute Necrotising Ulcerative Gingivitis 12
Early Acute Necrotising Gingivitis 12
Gingivitis, Necrotizing Ulcerative 44
Acute Ulceromembranous Gingivitis 12
Vincent's Angina - Pharyngitis 12
Vincent's Infection, Any Site 12
Acute Membranous Gingivitis 20
Fusospirillary Gingivitis 20
Phagedenic Gingivitis 20
Vincent's Gingivitis 20
Vincent's Stomatitis 20
Vincent's Infection 20
Angina - Vincents 12
Vincent's Angina 12
Fusospirillosis 20
Trench Mouth 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13924
ICD9CM 34 101
MeSH 44 D005892
NCIt 50 C34637
SNOMED-CT 67 171847006 707792000
ICD10 32 A69.1
UMLS 70 C0017575 C1444123 C1527368

Summaries for Necrotizing Ulcerative Gingivitis

MalaCards based summary : Necrotizing Ulcerative Gingivitis, also known as acute necrotizing ulcerative gingivitis, is related to gingivitis and periodontitis. An important gene associated with Necrotizing Ulcerative Gingivitis is GUSB (Glucuronidase Beta). The drug Analgesics has been mentioned in the context of this disorder. Related phenotype is homeostasis/metabolism.

Wikipedia : 73 Acute necrotizing ulcerative gingivitis (ANUG) is a common, non-contagious infection of the gums with... more...

Related Diseases for Necrotizing Ulcerative Gingivitis

Diseases related to Necrotizing Ulcerative Gingivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 46)
# Related Disease Score Top Affiliating Genes
1 gingivitis 11.1
2 periodontitis 10.5
3 noma 10.4
4 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.2
5 osteogenic sarcoma 10.2
6 tonsillitis 10.1
7 gingival disease 10.1
8 pfeiffer syndrome 10.1
9 alcohol dependence 10.1
10 systemic lupus erythematosus 10.1
11 periodontitis, chronic 10.1
12 human immunodeficiency virus type 1 10.1
13 disease by infectious agent 10.1
14 meningococcal meningitis 10.1
15 pemphigoid 10.1
16 osteomyelitis 10.1
17 cicatricial pemphigoid 10.1
18 von willebrand's disease 10.1
19 squamous cell papilloma 10.1
20 candidiasis 10.1
21 alcohol use disorder 10.1
22 histoplasmosis 10.1
23 hemorrhagic disease 10.1
24 papilloma 10.1
25 bruxism 10.1
26 syphilis 10.1
27 acquired immunodeficiency syndrome 10.1
28 lupus erythematosus 10.1
29 stomatitis 10.1
30 periodontosis 10.1
31 hemophilia 10.1
32 47,xyy 10.1
33 cytokine deficiency 10.1
34 stenotrophomonas maltophilia infection 10.1
35 herpes simplex 10.0
36 panophthalmitis 10.0 SUCLG2 CD4
37 bronchopneumonia 10.0 GUSB CD4
38 ulcerative stomatitis 10.0
39 purulent endophthalmitis 10.0 SUCLG2 CD4
40 balanitis 10.0
41 pellagra 10.0
42 aphthous stomatitis 10.0
43 chediak-higashi syndrome 9.9 GUSB CD4
44 hypoascorbemia 9.9
45 choroiditis 9.9 CFB CD4
46 cholangitis, primary sclerosing 9.7 DMBT1 CD4

Graphical network of the top 20 diseases related to Necrotizing Ulcerative Gingivitis:



Diseases related to Necrotizing Ulcerative Gingivitis

Symptoms & Phenotypes for Necrotizing Ulcerative Gingivitis

MGI Mouse Phenotypes related to Necrotizing Ulcerative Gingivitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.17 CD4 CFB DMBT1 DNAL4 GUSB SLURP1

Drugs & Therapeutics for Necrotizing Ulcerative Gingivitis

Drugs for Necrotizing Ulcerative Gingivitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Analgesics

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Photobiomodulation Therapy Using the MuReva Phototherapy System to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Patients With Head and Neck Cancer Receiving Concurrent Radiation and Chemotherapy Recruiting NCT03972527

Search NIH Clinical Center for Necrotizing Ulcerative Gingivitis

Cochrane evidence based reviews: gingivitis, necrotizing ulcerative

Genetic Tests for Necrotizing Ulcerative Gingivitis

Anatomical Context for Necrotizing Ulcerative Gingivitis

Publications for Necrotizing Ulcerative Gingivitis

Articles related to Necrotizing Ulcerative Gingivitis:

(show top 50) (show all 233)
# Title Authors PMID Year
1
Otolaryngeal and Oropharyngeal Conditions: Common Nontraumatic Dental Conditions. 61
33595265 2021
2
Indicators of antioxidant protection of blood in necrotizing ulcerative gingivitis in experimental animals. 61
33767788 2021
3
Oral spirochetes: Pathogenic mechanisms in periodontal disease. 61
32304795 2020
4
Bactericidal and clinical efficacy of photochemotherapy in acute necrotizing ulcerative gingivitis. 61
31988023 2020
5
Topical tetracycline in the treatment of a 7-year-old child with necrotizing ulcerative gingivitis: a case report. 61
32105224 2020
6
Evaluation of oral care protocols practice by dentists in Rio de Janeiro towards HIV/AIDS individuals. 61
31937291 2020
7
Oral histoplasmosis masquerading as acute necrotizing ulcerative gingivitis: A rare case report. 61
31501651 2019
8
Clinical treatment of necrotizing ulcerative gingivitis: a case report with 10-year follow-up. 61
31199747 2019
9
Evaluation of dental students' knowledge and patient care towards HIV/AIDS individuals. 61
30681237 2019
10
Antibiotic Prescribing for Oro-Facial Infections in the Paediatric Outpatient: A Review. 61
29693642 2018
11
Adjunct Use of Low-Level Laser Therapy on the Treatment of Necrotizing Ulcerative Gingivitis: A Case Report. 61
29399316 2018
12
Unexpected Acute Necrotizing Ulcerative Gingivitis in a Well-controlled HIV-infected Case. 61
28781315 2017
13
Necrotizing Ulcerative Gingivitis. 61
29042743 2017
14
Prevalence and treatment of necrotizing ulcerative gingivitis (NUG) in the British Armed Forces: a case-control study. 61
27830369 2017
15
Necrotizing Periodontal Diseases in Children: A Literature Review and Adjustment of Treatment. 61
26966241 2016
16
[Aphthous ulcers and oral ulcerations]. 61
26880080 2016
17
Differential Diagnosis and Treatment Proposal for Acute Endodontic Infection. 61
27018033 2015
18
Periodontal disease in children and adolescents of Latin America. 61
25494597 2015
19
Complete Genome Sequence for Treponema sp. OMZ 838 (ATCC 700772, DSM 16789), Isolated from a Necrotizing Ulcerative Gingivitis Lesion. 61
25540346 2014
20
[NUG--necrotizing ulcerative gingivitis: a review]. 61
25219100 2014
21
Evaluation of Calendula officinalis as an anti-plaque and anti-gingivitis agent. 61
24554883 2013
22
Associated oral lesions in human immunodefeciency virus infected children of age 1 to 14 years in anti retroviral therapy centers in Tamil Nadu. 61
24403790 2013
23
Periodontal disease in HIV-infected adults in the HAART era: Clinical, immunological, and microbiological aspects. 61
23755999 2013
24
Necrotizing ulcerative gingivitis and the orthodontic patient: a case series. 61
23524550 2013
25
Managing patients with necrotizing ulcerative gingivitis. 61
23763733 2013
26
The phylum Synergistetes in gingivitis and necrotizing ulcerative gingivitis. 61
22878253 2012
27
Prevalence of necrotizing ulcerative gingivitis and associated factors in Koranic boarding schools in Senegal. 61
22779382 2012
28
Gingival bleeding and jaw bone necrosis in patients with metastatic renal cell carcinoma receiving sunitinib: report of 2 cases with clinical implications. 61
22669112 2012
29
Necrotizing periodontal diseases in HIV-infected Brazilian patients: a clinical and microbiologic descriptive study. 61
22259811 2012
30
Necrotizing ulcerative gingivitis: a discussion of four dissimilar presentations. 61
22206178 2011
31
Comparison of oral manifestations with CD4 count in HIV-infected patients. 61
22406727 2011
32
HIV infection and periodontal diseases: an overview of the post-HAART era. 61
21029260 2011
33
Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles. 61
20618700 2010
34
[Progress on study on oral lesions in patients with AIDS]. 61
20140059 2010
35
Gingival health in relation to clinical crown length: a case report. 61
20062553 2009
36
[Effects of smoking on periodontal disease]. 61
20032842 2009
37
Contextual effects in the occurrence of periodontal attachment loss and necrotizing gingival lesions among adolescents. 61
19758251 2009
38
An atypical form of necrotizing periodontitis. 61
19722808 2009
39
Gingival health in relation to clinical crown length: a case report. 61
20184687 2009
40
Current management of upper respiratory tract and head and neck infections. 61
18985371 2009
41
Predicting HIV in a public dental facility using group I oral lesions. 61
19322964 2008
42
Oral health impact of periodontal diseases in adolescents. 61
17959905 2007
43
Uncultivated Tannerella BU045 and BU063 are slim segmented filamentous rods of high prevalence but low abundance in inflammatory disease-associated dental plaques. 61
17975090 2007
44
Oral hygiene and nutritional status of children aged 1-7 years in a rural community. 61
17299560 2006
45
Images in emergency medicine. Acute necrotizing ulcerative gingivitis. 61
16492485 2006
46
Genotypic and phenotypic characterization of fusobacteria from Chinese and European patients with inflammatory periodontal diseases. 61
16464693 2006
47
Complex oral manifestations of an HIV-seropositive patient. 61
16459884 2006
48
Inflammatory cytokine profile and circulating cortisol levels in malnourished children with necrotizing ulcerative gingivitis. 61
16266866 2005
49
Oral lesions in infection with human immunodeficiency virus. 61
16211162 2005
50
Pattern of dental extraction in children in a Nigerian tertiary hospital. 61
15915207 2005

Variations for Necrotizing Ulcerative Gingivitis

Expression for Necrotizing Ulcerative Gingivitis

Search GEO for disease gene expression data for Necrotizing Ulcerative Gingivitis.

Pathways for Necrotizing Ulcerative Gingivitis

GO Terms for Necrotizing Ulcerative Gingivitis

Biological processes related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-negative bacterium GO:0050829 8.62 DMBT1 CD4

Sources for Necrotizing Ulcerative Gingivitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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