MCID: NCR001
MIFTS: 38

Necrotizing Ulcerative Gingivitis

Categories: Rare diseases, Oral diseases

Aliases & Classifications for Necrotizing Ulcerative Gingivitis

MalaCards integrated aliases for Necrotizing Ulcerative Gingivitis:

Name: Necrotizing Ulcerative Gingivitis 12 15 73
Acute Necrotizing Ulcerative Gingivitis 12 76 53
Vincent's Disease 12 73
Vincent Angina 12 73
Anug 12 53
Acute Necrotising Ulcerative Gingivostomatitis 12
Acute Necrotizing Ulcerative Gingivostomatitis 12
Acute Necrotising Ulcerative Gingivitis 12
Early Acute Necrotising Gingivitis 12
Gingivitis, Necrotizing Ulcerative 44
Acute Ulceromembranous Gingivitis 12
Vincent's Angina - Pharyngitis 12
Vincent's Infection, Any Site 12
Acute Membranous Gingivitis 53
Fusospirillary Gingivitis 53
Phagedenic Gingivitis 53
Vincent's Gingivitis 53
Vincent's Stomatitis 53
Vincent's Infection 53
Angina - Vincents 12
Vincent's Angina 12
Fusospirillosis 53
Trench Mouth 12

Classifications:



Summaries for Necrotizing Ulcerative Gingivitis

MalaCards based summary : Necrotizing Ulcerative Gingivitis, also known as acute necrotizing ulcerative gingivitis, is related to gingivitis and mucolipidosis iii alpha/beta. An important gene associated with Necrotizing Ulcerative Gingivitis is GUSB (Glucuronidase Beta), and among its related pathways/superpathways are IL4-mediated signaling events and Staphylococcus aureus infection. Affiliated tissues include bone, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 76 Acute necrotizing ulcerative gingivitis (ANUG; colloquially known as trench mouth) is a common,... more...

Related Diseases for Necrotizing Ulcerative Gingivitis

Diseases related to Necrotizing Ulcerative Gingivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Related Disease Score Top Affiliating Genes
1 gingivitis 10.8
2 mucolipidosis iii alpha/beta 10.5 BSG GUSB
3 acalculous cholecystitis 10.5 CD40LG GUSB
4 bronchopneumonia 10.5 CD40LG GUSB
5 periodontitis 10.2
6 periodontosis 10.2 CD40LG PTGES
7 severe acute respiratory syndrome 10.1 CD40LG CTRL
8 schnitzler syndrome 10.1 CD40LG IL18
9 multifocal choroiditis 10.1 CFB IL10
10 choroiditis 10.1 CFB IL10
11 cutaneous lupus erythematosus 10.0 CD40LG IL18
12 leukemia 10.0
13 ross river fever 9.9 CD40LG IL10
14 immunoglobulin a deficiency 1 9.9 CD40LG IL10
15 sporotrichosis 9.9 CD40LG IL10
16 buruli ulcer 9.9 CD40LG IL10
17 primary systemic mycosis 9.9 CD40LG IL10
18 cystic echinococcosis 9.9 CD40LG IL10
19 coccidiosis 9.8 CD40LG IL10
20 hemorrhagic fever 9.8 CD40LG IL10
21 panuveitis 9.8 CD40LG IL10
22 scrub typhus 9.8 CD40LG IL10
23 systemic lupus erythematosus 9.8
24 acute lymphocytic leukemia 9.8
25 von willebrand's disease 9.8
26 bruxism 9.8
27 lupus erythematosus 9.8
28 stomatitis 9.8
29 noma 9.8
30 plasmodium vivax malaria 9.8 CD40LG IL10
31 q fever 9.8 CD40LG IL10
32 churg-strauss syndrome 9.8 CD40LG IL10
33 hemorrhagic fever with renal syndrome 9.8 CD40LG IL10
34 extrinsic cardiomyopathy 9.8 CD40LG IL10
35 idiopathic neutropenia 9.8 CD40LG IL10
36 opportunistic mycosis 9.8 CD40LG IL10
37 mixed connective tissue disease 9.8 CD40LG IL10
38 echinococcosis 9.8 CD40LG IL10
39 cow milk allergy 9.7 IL10 IL18
40 leptospirosis 9.7 CD40LG IL10
41 secondary progressive multiple sclerosis 9.7 CD40LG IL10
42 genital herpes 9.7 IL10 IL18
43 brucellosis 9.7 CD40LG IL10
44 parasitic helminthiasis infectious disease 9.7 CD40LG IL10
45 upper respiratory tract disease 9.7 CD40LG IL10
46 primary sjögren syndrome 9.7 CD40LG IL10
47 acute graft versus host disease 9.7 IL10 IL18
48 dengue hemorrhagic fever 9.7 CD40LG IL10
49 human immunodeficiency virus infectious disease 9.6 CD40LG IL10
50 paracoccidioidomycosis 9.6 IL10 IL18

Graphical network of the top 20 diseases related to Necrotizing Ulcerative Gingivitis:



Diseases related to Necrotizing Ulcerative Gingivitis

Symptoms & Phenotypes for Necrotizing Ulcerative Gingivitis

MGI Mouse Phenotypes related to Necrotizing Ulcerative Gingivitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.8 CD40LG CFB GUSB IL10 IL18 PTGES
2 homeostasis/metabolism MP:0005376 9.7 CD40LG CFB GLA GUSB IL10 IL18
3 immune system MP:0005387 9.5 BSG CD40LG CFB GLA IL10 IL18
4 integument MP:0010771 9.02 CD40LG GUSB IL10 IL18 PTGES

Drugs & Therapeutics for Necrotizing Ulcerative Gingivitis

Search Clinical Trials , NIH Clinical Center for Necrotizing Ulcerative Gingivitis

Cochrane evidence based reviews: gingivitis, necrotizing ulcerative

Genetic Tests for Necrotizing Ulcerative Gingivitis

Anatomical Context for Necrotizing Ulcerative Gingivitis

MalaCards organs/tissues related to Necrotizing Ulcerative Gingivitis:

41
Bone

Publications for Necrotizing Ulcerative Gingivitis

Articles related to Necrotizing Ulcerative Gingivitis:

(show top 50) (show all 105)
# Title Authors Year
1
Adjunct Use of Low-Level Laser Therapy on the Treatment of Necrotizing Ulcerative Gingivitis: A Case Report. ( 29399316 )
2018
2
Unexpected Acute Necrotizing Ulcerative Gingivitis in a Well-controlled HIV-infected Case. ( 28781315 )
2017
3
Necrotizing Ulcerative Gingivitis. ( 29042743 )
2017
4
Prevalence and treatment of necrotizing ulcerative gingivitis (NUG) in the British Armed Forces: a case-control study. ( 27830369 )
2016
5
Complete Genome Sequence for Treponema sp. OMZ 838 (ATCC 700772, DSM 16789), Isolated from a Necrotizing Ulcerative Gingivitis Lesion. ( 25540346 )
2014
6
Managing patients with necrotizing ulcerative gingivitis. ( 23763733 )
2013
7
Necrotizing ulcerative gingivitis and the orthodontic patient: a case series. ( 23524550 )
2013
8
The phylum Synergistetes in gingivitis and necrotizing ulcerative gingivitis. ( 22878253 )
2012
9
Prevalence of necrotizing ulcerative gingivitis and associated factors in Koranic boarding schools in Senegal. ( 22779382 )
2012
10
Necrotizing ulcerative gingivitis: a discussion of four dissimilar presentations. ( 22206178 )
2011
11
Images in emergency medicine. Acute necrotizing ulcerative gingivitis. ( 16492485 )
2006
12
Inflammatory cytokine profile and circulating cortisol levels in malnourished children with necrotizing ulcerative gingivitis. ( 16266866 )
2005
13
Acute necrotizing ulcerative gingivitis and bacteremia caused by Stenotrophomonas maltophilia in an immunocompromised host. ( 15702051 )
2005
14
Gingival crevice microbiota from Chinese patients with gingivitis or necrotizing ulcerative gingivitis. ( 14871191 )
2004
15
Treponema putidum sp. nov., a medium-sized proteolytic spirochaete isolated from lesions of human periodontitis and acute necrotizing ulcerative gingivitis. ( 15280279 )
2004
16
The epidemiology, etiology, and pathophysiology of acute necrotizing ulcerative gingivitis associated with malnutrition. ( 15318254 )
2004
17
Acute myelogenous leukemia complicated by acute necrotizing ulcerative gingivitis due to Aspergillus terreus. ( 12769350 )
2003
18
Oral pemphigoid masquerading as necrotizing ulcerative gingivitis in a child. ( 12083540 )
2002
19
Treponema parvum sp. nov., a small, glucoronic or galacturonic acid-dependent oral spirochaete from lesions of human periodontitis and acute necrotizing ulcerative gingivitis. ( 11411720 )
2001
20
Necrotizing ulcerative gingivitis. ( 10863376 )
1999
21
Acute necrotizing ulcerative gingivitis-periodontitis: a literature review. ( 9597852 )
1998
22
Human Herpesviridae in acute necrotizing ulcerative gingivitis in children in Nigeria. ( 9467378 )
1997
23
Severity of necrotizing ulcerative gingivitis in Nigerian children. ( 9055679 )
1995
24
Case #1. Acute necrotizing ulcerative gingivitis. ( 8619074 )
1995
25
Necrotizing ulcerative gingivitis, periodontitis, and stomatitis: clinical staging and predisposing factors. ( 8558402 )
1995
26
Acute necrotizing ulcerative gingivitis: risk factors involving host defense mechanisms. ( 9673175 )
1994
27
Oral hygiene status and necrotizing ulcerative gingivitis in Nigerian children. ( 8295093 )
1993
28
Serum IgG and IgM levels to bacterial antigens in necrotizing ulcerative gingivitis. ( 8463942 )
1993
29
Identification of spirochetes related to Treponema pallidum in necrotizing ulcerative gingivitis and chronic periodontitis. ( 1713299 )
1991
30
The treatment of acute necrotizing ulcerative gingivitis. ( 2068255 )
1991
31
Acute necrotizing ulcerative gingivitis is associated with attachment loss. ( 1753002 )
1991
32
Pathogen-related spirochetes identified within gingival tissue from patients with acute necrotizing ulcerative gingivitis. ( 1855985 )
1991
33
The problem of the taxonomy of the fusiform bacillus of acute necrotizing ulcerative gingivitis (Vincent's gingivitis). ( 2196849 )
1990
34
Spirochetes in early lesions of necrotizing ulcerative gingivitis experimentally induced in beagles. ( 2087354 )
1990
35
Acute necrotizing ulcerative gingivitis associated with von Willebrand's disease: a case report. ( 2150929 )
1990
36
Allelic variants for complement factors C3, C4, and B in acute necrotizing ulcerative gingivitis. ( 3163352 )
1988
37
A case-control study of plasma ascorbate and acute necrotizing ulcerative gingivitis. ( 3163353 )
1988
38
Epidemiology of acute necrotizing ulcerative gingivitis. ( 3066627 )
1988
39
Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. ( 3514841 )
1986
40
Peripheral blood phagocyte function in acute necrotizing ulcerative gingivitis. ( 2941561 )
1986
41
Acute necrotizing ulcerative gingivitis: etiology and stress relationships. ( 3462166 )
1986
42
Necrotizing ulcerative gingivitis in the military from ancient to modern times. ( 3935959 )
1985
43
ABC's periodontics. "N" is for necrotizing ulcerative gingivitis. ( 3866022 )
1985
44
Necrotizing ulcerative gingivitis in beagle dogs. III. Distribution of spirochetes in interdental gingival tissue. ( 2934537 )
1985
45
Acute necrotizing ulcerative gingivitis in a case of systemic lupus erythematosus. ( 3855317 )
1985
46
Necrotizing ulcerative gingivitis in beagle dogs. I. Attempts at unilateral induction and intraoral transmission of NUG, a microbiological and clinical study. ( 6232371 )
1984
47
Necrotizing ulcerative gingivitis in beagle dogs. II. Histologic characteristics of NUG in relation to interproximal contacts. ( 6232372 )
1984
48
Acute necrotizing ulcerative gingivitis: a review. ( 6594833 )
1984
49
Acute necrotizing ulcerative gingivitis: clinical features, etiology and treatment. ( 6585327 )
1984
50
Demographic and clinical data associated with acute necrotizing ulcerative gingivitis in a dental school population (ANUG-demographic and clinical data). ( 6592176 )
1984

Variations for Necrotizing Ulcerative Gingivitis

Expression for Necrotizing Ulcerative Gingivitis

Search GEO for disease gene expression data for Necrotizing Ulcerative Gingivitis.

Pathways for Necrotizing Ulcerative Gingivitis

Pathways related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.17 CD40LG IL10
2 11.07 CFB IL10
3 10.98 CD40LG IL10
4 10.85 IL10 IL18
5 10.5 IL10 IL18
6 10.49 CD40LG IL10 IL18

GO Terms for Necrotizing Ulcerative Gingivitis

Cellular components related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.43 CD40LG CFB GLA GUSB IL10 IL18
2 extracellular space GO:0005615 9.1 CD40LG CFB CTRL GUSB IL10 IL18

Biological processes related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 B cell proliferation GO:0042100 9.16 CD40LG IL10
2 negative regulation of nitric oxide biosynthetic process GO:0045019 8.96 GLA IL10
3 type 2 immune response GO:0042092 8.62 IL10 IL18

Molecular functions related to Necrotizing Ulcerative Gingivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.13 CD40LG IL10 IL18
2 hydrolase activity, hydrolyzing O-glycosyl compounds GO:0004553 8.62 GLA GUSB

Sources for Necrotizing Ulcerative Gingivitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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