MCID: NNT054
MIFTS: 15

Neonatal Alloimmune Neutropenia

Categories: Blood diseases, Rare diseases

Aliases & Classifications for Neonatal Alloimmune Neutropenia

MalaCards integrated aliases for Neonatal Alloimmune Neutropenia:

Name: Neonatal Alloimmune Neutropenia 60
Neutropenia, Alloimmune Neonatal 13

Classifications:

Orphanet: 60  
Rare immunological diseases


External Ids:

ICD10 via Orphanet 35 P61.5
Orphanet 60 ORPHA464370

Summaries for Neonatal Alloimmune Neutropenia

MalaCards based summary : Neonatal Alloimmune Neutropenia, also known as neutropenia, alloimmune neonatal, is related to neutropenia and thrombocytopenia. An important gene associated with Neonatal Alloimmune Neutropenia is CD177 (CD177 Molecule). Affiliated tissues include neutrophil.

Related Diseases for Neonatal Alloimmune Neutropenia

Diseases related to Neonatal Alloimmune Neutropenia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 neutropenia 30.2 CD177 FCGR3B
2 thrombocytopenia 10.1

Symptoms & Phenotypes for Neonatal Alloimmune Neutropenia

Drugs & Therapeutics for Neonatal Alloimmune Neutropenia

Search Clinical Trials , NIH Clinical Center for Neonatal Alloimmune Neutropenia

Genetic Tests for Neonatal Alloimmune Neutropenia

Anatomical Context for Neonatal Alloimmune Neutropenia

MalaCards organs/tissues related to Neonatal Alloimmune Neutropenia:

42
Neutrophil

Publications for Neonatal Alloimmune Neutropenia

Articles related to Neonatal Alloimmune Neutropenia:

(show all 15)
# Title Authors Year
1
Antibodies to human neutrophil antigen HNA-3b implicated in cases of neonatal alloimmune neutropenia. ( 29451309 )
2018
2
Antibodies to human neutrophil antigen HNA-4b implicated in a case of neonatal alloimmune neutropenia. ( 26749553 )
2016
3
Management and outcome of 35 cases with foetal/neonatal alloimmune neutropenia. ( 25039288 )
2014
4
Neonatal alloimmune neutropenia: still a diagnostic and therapeutical challenge. ( 22995923 )
2012
5
Neonatal alloimmune neutropenia due to immunoglobulin G antibodies against human neutrophil antigen-5a. ( 20735765 )
2011
6
Intravenous immunoglobulins for neonatal alloimmune neutropenia refractory to recombinant human granulocyte colony-stimulating factor. ( 21136350 )
2011
7
Granulocyte colony stimulating factor in neonatal alloimmune neutropenia: a possible association with induced thrombocytopenia. ( 20135695 )
2010
8
Dizygotic twins with neonatal alloimmune neutropenia associated with maternal anti-human neutrophil antigen-1B antibody. ( 19379263 )
2009
9
A case of neonatal alloimmune neutropenia associated with anti-human neutrophil antigen-1a (HNA-1a) antibody. ( 16614528 )
2006
10
Neonatal alloimmune neutropenia attributed to maternal immunoglobulin G antibodies against the neutrophil alloantigen HNA-1c (SH): a report of five cases. ( 16078917 )
2005
11
Neonatal alloimmune neutropenia due to anti-HNA-1b. ( 17159404 )
2002
12
Resistance to recombinant human granulocyte colony-stimulating factor in neonatal alloimmune neutropenia associated with anti-human neutrophil antigen-2a (NB1) antibodies. ( 11927737 )
2002
13
Neonatal alloimmune neutropenia in premature monozygous twins. ( 10920162 )
2000
14
Neutrophil antigen 5b is carried by a protein, migrating from 70 to 95 kDa, and may be involved in neonatal alloimmune neutropenia. ( 10686007 )
2000
15
Frequency of the polymorphonuclear neutrophil Fc gamma receptor III deficiency in the French population and its involvement in the development of neonatal alloimmune neutropenia. ( 1532916 )
1992

Variations for Neonatal Alloimmune Neutropenia

Expression for Neonatal Alloimmune Neutropenia

Search GEO for disease gene expression data for Neonatal Alloimmune Neutropenia.

Pathways for Neonatal Alloimmune Neutropenia

GO Terms for Neonatal Alloimmune Neutropenia

Cellular components related to Neonatal Alloimmune Neutropenia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 anchored component of membrane GO:0031225 8.96 CD177 FCGR3B
2 secretory granule membrane GO:0030667 8.62 CD177 FCGR3B

Biological processes related to Neonatal Alloimmune Neutropenia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 8.62 CD177 FCGR3B

Sources for Neonatal Alloimmune Neutropenia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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