MCID: NNT021
MIFTS: 27

Neonatal Meningitis

Categories: Rare diseases

Aliases & Classifications for Neonatal Meningitis

MalaCards integrated aliases for Neonatal Meningitis:

Name: Neonatal Meningitis 54 74
Meningitis, Neonatal 54

Classifications:



External Ids:

UMLS 74 C0456107

Summaries for Neonatal Meningitis

MalaCards based summary : Neonatal Meningitis, also known as meningitis, neonatal, is related to meningitis and bacterial meningitis. An important gene associated with Neonatal Meningitis is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways/superpathways are Pathways in cancer and Glucose / Energy Metabolism. The drugs Ampicillin and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and breast.

Wikipedia : 77 Neonatal meningitis is a serious medical condition in infants. Meningitis is an inflammation of the... more...

Related Diseases for Neonatal Meningitis

Diseases related to Neonatal Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
# Related Disease Score Top Affiliating Genes
1 meningitis 10.9
2 bacterial meningitis 10.1
3 meningococcal meningitis 10.0
4 enterocolitis 9.8
5 arachnoiditis 9.8
6 acute cystitis 9.8
7 cystitis 9.8
8 perinatal necrotizing enterocolitis 9.8
9 haemophilus influenzae 9.8
10 otitis media 9.7
11 hydrocephalus due to congenital stenosis of aqueduct of sylvius 9.7
12 brain injury 9.7
13 hydrocephalus 9.7
14 porencephaly 9.7
15 mastoiditis 9.7
16 salmonellosis 9.7
17 osteomyelitis 9.7
18 endocarditis 9.7
19 mastitis 9.7
20 myocarditis 9.7
21 diabetes insipidus 9.7
22 encephalitis 9.7
23 tuberculous meningitis 9.7
24 pneumococcal meningitis 9.7
25 hyperglycemia 9.7 PPARG SLC2A1
26 large intestine cancer 9.6 PPARG SLC2A1
27 thyroid cancer 9.6 PPARG SLC2A1
28 body mass index quantitative trait locus 11 9.4 PPARG SLC2A1

Graphical network of the top 20 diseases related to Neonatal Meningitis:



Diseases related to Neonatal Meningitis

Symptoms & Phenotypes for Neonatal Meningitis

Drugs & Therapeutics for Neonatal Meningitis

Drugs for Neonatal Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ampicillin Approved, Vet_approved Phase 2, Phase 3 69-53-4 6249
2 Anti-Bacterial Agents Phase 2, Phase 3
3 Gentamicins Phase 2, Phase 3
4 Anti-Infective Agents Phase 2, Phase 3
5 Antibiotics, Antitubercular Phase 2, Phase 3
6 Antitubercular Agents Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Completed NCT01633294 Phase 2, Phase 3 Ampicillin + gentamicin
2 Infection, Sepsis and Meningitis in Surinamese Neonates Completed NCT02486783
3 Intrapartum Rapid GBS Testing in Patients Presenting With Threatened Preterm Labor Active, not recruiting NCT02511444 Not Applicable

Search NIH Clinical Center for Neonatal Meningitis

Genetic Tests for Neonatal Meningitis

Anatomical Context for Neonatal Meningitis

MalaCards organs/tissues related to Neonatal Meningitis:

42
Brain, Testes, Breast

Publications for Neonatal Meningitis

Articles related to Neonatal Meningitis:

(show top 50) (show all 289)
# Title Authors Year
1
Genome sequencing of strains of the most prevalent clonal group of O1:K1:H7 Escherichia coli that causes neonatal meningitis in France. ( 30654756 )
2019
2
Early-Onset Neonatal Meningitis Caused by an Unusual Pathogen-Moraxella catarrhalis. ( 30729056 )
2019
3
Treatment of Elizabethkingia meningoseptica Neonatal Meningitis with Combination Systemic and Intraventricular Therapy. ( 30790188 )
2019
4
Draft Genome Sequences of Five Neonatal Meningitis-Causing Escherichia coli Isolates (SP-4, SP-5, SP-13, SP-46, and SP-65). ( 29674529 )
2018
5
Neonatal meningitis and recurrent bacteremia with group B Streptococcus transmitted by own mother's milk: A case report and review of previous cases. ( 29959094 )
2018
6
Ring-enhancing lesions in neonatal meningitis: an analysis of neuroradiology pitfalls through exemplificative cases and a review of the literature. ( 29774186 )
2018
7
Unexpected Ventriculitis Complication of Neonatal Meningitis Caused by Streptococcus gallolyticus Subsp. pasteurianus: a Case Report. ( 29279439 )
2018
8
Reagent Strips as an Aid to Diagnosis of Neonatal Meningitis in a Resource-limited Setting. ( 29390160 )
2018
9
C-Reactive Protein (CRP) levels in neonatal meningitis in England: an analysis of national variations in CRP cut-offs for lumbar puncture. ( 30509228 )
2018
10
Complete Genome Sequence of the Multidrug-Resistant Neonatal Meningitis Escherichia coli Serotype O75:H5:K1 Strain mcjchv-1 (NMEC-O75). ( 30533615 )
2018
11
Neonatal meningitis and maternal sepsis caused by Streptococcus oralis. ( 30040747 )
2018
12
Neonatal cranial sonography: ultrasound findings in neonatal meningitis-a pictorial review. ( 28275563 )
2017
13
Bacterial aetiology of neonatal meningitis: A study from north-east India. ( 28574028 )
2017
14
Neonatal Meningitis: Overcoming Challenges in Diagnosis, Prognosis, and Treatment with Omics. ( 28670576 )
2017
15
Neuroimaging Complication of Neonatal Meningitis in Full-Term and Near-Term Newborns: A Retrospective Study of One Center. ( 28229093 )
2016
16
Escherichia coli K1 Modulates Peroxisome Proliferator-Activated Receptor I^ and Glucose Transporter 1 at the Blood-Brain Barrier in Neonatal Meningitis. ( 27456707 )
2016
17
Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review. ( 27648334 )
2016
18
Closing the Brief Case: Neonatal Meningitis Caused by Listeria monocytogenes Diagnosed by Multiplex Molecular Panel. ( 27881637 )
2016
19
The Brief Case: Neonatal Meningitis Caused by Listeria monocytogenes Diagnosed by Multiplex Molecular Panel. ( 27881634 )
2016
20
Complete Genome Sequence of the Neonatal Meningitis-Causing Escherichia coli Strain NMEC O18. ( 27811114 )
2016
21
Neonatal meningitis and septicaemia caused by Salmonella agama. ( 26255922 )
2015
22
Characterizing the pathotype of neonatal meningitis causing Escherichia coli (NMEC). ( 26467858 )
2015
23
An Unusual Cause of Neonatal Meningitis. ( 25825073 )
2015
24
Complete Genome Sequence of Escherichia coli Strain RS218 (O18:H7:K1), Associated with Neonatal Meningitis. ( 26205862 )
2015
25
Capsular profiling of the Cronobacter genus and the association of specific Cronobacter sakazakii and C. malonaticus capsule types with neonatal meningitis and necrotizing enterocolitis. ( 26449318 )
2015
26
Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis. ( 26407066 )
2015
27
Comparative study of bacteriological culture and real-time fluorescence quantitative PCR (RT-PCR) and multiplex PCR-based reverse line blot (mPCR/RLB) hybridization assay in the diagnosis of bacterial neonatal meningitis. ( 25200110 )
2014
28
Angiotensin II Receptor Type 1--A Novel Target for Preventing Neonatal Meningitis in Mice by Escherichia coli K1. ( 24041786 )
2014
29
Neonatal meningitis complicating with pneumocephalus. ( 24741257 )
2014
30
Neonatal Meningitis by Multidrug Resistant Elizabethkingia meningosepticum Identified by 16S Ribosomal RNA Gene Sequencing. ( 24678326 )
2014
31
Preterm delivery and neonatal meningitis due to transplacental acquisition of non-typhoidal Salmonella serovar montevideo. ( 24876215 )
2014
32
Sneathia species in a case of neonatal meningitis from Northeast India. ( 25988049 )
2014
33
Successful off-label use of the Cepheid Xpert GBS in a late-onset neonatal meningitis by Streptococcus agalactiae. ( 25197396 )
2014
34
Neonatal meningitis: risk factors, causes, and neurologic complications. ( 25657770 )
2014
35
Neonatal Meningitis due to Neisseria meningitidis Serogroup Y. ( 25228622 )
2014
36
Medical and neurosurgical management of Citrobacter koseri, a rare cause of neonatal meningitis. ( 24243285 )
2014
37
The ssbL gene harbored by the ColV plasmid of an Escherichia coli neonatal meningitis strain is an auxiliary virulence factor boosting the production of siderophores through the shikimate pathway. ( 24443535 )
2014
38
Evaluation of the brain-derived neurotrophic factor, nerve growth factor and memory in adult rats survivors of the neonatal meningitis by Streptococcus agalactiae. ( 22683802 )
2013
39
Dexamethasone for management of neonatal meningitis. ( 23355014 )
2013
40
Neonatal meningitis associated with osteomyelitis and epidural empyema. ( 23975909 )
2013
41
Role of dexamethasone in neonatal meningitis: a randomized controlled trial. ( 23054852 )
2013
42
A Case of Myocarditis Following Neonatal Meningitis Caused by Coxsackievirus B1 in Spite of Intravenous Immunoglobulin Treatment. ( 24122863 )
2013
43
Cronobacter: an emerging opportunistic pathogen associated with neonatal meningitis, sepsis and necrotizing enterocolitis. ( 23538645 )
2013
44
Cronobacter sakazakii ST4 strains and neonatal meningitis, United States. ( 23260316 )
2013
45
Neonatal Meningitis and Sepsis by Chryseobacterium indologenes: A Rare and Resistant Bacterium. ( 23681831 )
2013
46
Neonatal meningitis due to Morganella morganii. ( 22267858 )
2013
47
'Leptotrichia amnionii', a newly reported cause of early onset neonatal meningitis. ( 23378562 )
2013
48
Neonatal meningitis and the developing world. ( 22035279 )
2012
49
Genotypic and phenotypic traits that distinguish neonatal meningitis-associated Escherichia coli from fecal E. coli isolates of healthy human hosts. ( 22706051 )
2012
50
Neonatal meningitis caused by Streptococcus gallolyticus subsp. pasteurianus. ( 22002578 )
2012

Variations for Neonatal Meningitis

Expression for Neonatal Meningitis

Search GEO for disease gene expression data for Neonatal Meningitis.

Pathways for Neonatal Meningitis

Pathways related to Neonatal Meningitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.68 PPARG SLC2A1
2 11.11 PPARG SLC2A1

GO Terms for Neonatal Meningitis

Molecular functions related to Neonatal Meningitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein self-association GO:0043621 8.62 PPARG SLC2A1

Sources for Neonatal Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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