MCID: NNT025
MIFTS: 16

Neonatal Systemic Lupus Erythematosus

Categories: Rare diseases, Bone diseases

Aliases & Classifications for Neonatal Systemic Lupus Erythematosus

MalaCards integrated aliases for Neonatal Systemic Lupus Erythematosus:

Name: Neonatal Systemic Lupus Erythematosus 53 73
Congenital Lupus Erythematosus 53
Neonatal Lupus Syndrome 53
Congenital Lupus 53
Neonatal Lupus 53
Neonatal Sle 53

Classifications:



External Ids:

UMLS 73 C0409979

Summaries for Neonatal Systemic Lupus Erythematosus

MalaCards based summary : Neonatal Systemic Lupus Erythematosus, also known as congenital lupus erythematosus, is related to neonatal lupus erythematosus and systemic lupus erythematosus. The drugs Rho(D) Immune Globulin and gamma-Globulins have been mentioned in the context of this disorder. Affiliated tissues include heart.

Related Diseases for Neonatal Systemic Lupus Erythematosus

Diseases in the Neonatal Lupus Erythematosus family:

Neonatal Systemic Lupus Erythematosus

Diseases related to Neonatal Systemic Lupus Erythematosus via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 neonatal lupus erythematosus 11.6
2 systemic lupus erythematosus 9.8
3 lupus erythematosus 9.8
4 atrial standstill 1 9.5
5 hydrops fetalis 9.5

Graphical network of the top 20 diseases related to Neonatal Systemic Lupus Erythematosus:



Diseases related to Neonatal Systemic Lupus Erythematosus

Symptoms & Phenotypes for Neonatal Systemic Lupus Erythematosus

Drugs & Therapeutics for Neonatal Systemic Lupus Erythematosus

Drugs for Neonatal Systemic Lupus Erythematosus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Rho(D) Immune Globulin Phase 2, Phase 3
2 gamma-Globulins Phase 2, Phase 3
3 Antibodies Phase 2, Phase 3,Not Applicable
4 Immunoglobulins Phase 2, Phase 3,Not Applicable
5 Immunoglobulins, Intravenous Phase 2, Phase 3
6 Autoantibodies Phase 2, Phase 3
7
Hydroxychloroquine Approved Phase 2 118-42-3 3652
8 Anti-Infective Agents Phase 2
9 Antiparasitic Agents Phase 2
10 Antiprotozoal Agents Phase 2
11 Antimalarials Phase 2
12 Antirheumatic Agents Phase 2
13
Dexamethasone Approved, Investigational, Vet_approved Not Applicable 50-02-2 5743
14 Dexamethasone acetate Not Applicable 1177-87-3
15 glucocorticoids Not Applicable
16
protease inhibitors Not Applicable
17 Gastrointestinal Agents Not Applicable
18 HIV Protease Inhibitors Not Applicable
19 Hormone Antagonists Not Applicable
20 Hormones Not Applicable
21 Hormones, Hormone Substitutes, and Hormone Antagonists Not Applicable
22 Peripheral Nervous System Agents Not Applicable
23 Antiemetics Not Applicable
24 Anti-Inflammatory Agents Not Applicable
25 BB 1101 Not Applicable
26 Autonomic Agents Not Applicable
27 Antineoplastic Agents, Hormonal Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Preventive IVIG Therapy for Congenital Heart Block Completed NCT00460928 Phase 2, Phase 3 intravenous immune globulin (IVIG)
2 Preventive Approach to Congenital Heart Block With Hydroxychloroquine Recruiting NCT01379573 Phase 2 Hydroxychloroquine
3 Dexamethasone Treatment for Congenital Heart Block (CHB) in Newborns With Lupus Completed NCT00007358 Not Applicable Dexamethasone or other corticosteroid
4 The Research Registry for Neonatal Lupus Recruiting NCT00074373
5 Prospective Maternal Surveillance of SSA (Sjögren Syndrome A) Positive Pregnancies Using a Hand-held Fetal Heart Rate Monitor Recruiting NCT02920346

Search NIH Clinical Center for Neonatal Systemic Lupus Erythematosus

Genetic Tests for Neonatal Systemic Lupus Erythematosus

Anatomical Context for Neonatal Systemic Lupus Erythematosus

MalaCards organs/tissues related to Neonatal Systemic Lupus Erythematosus:

41
Heart

Publications for Neonatal Systemic Lupus Erythematosus

Articles related to Neonatal Systemic Lupus Erythematosus:

# Title Authors Year
1
Neonatal Systemic Lupus Erythematosus Syndrome: a Comprehensive Review. ( 29116459 )
2017

Variations for Neonatal Systemic Lupus Erythematosus

Expression for Neonatal Systemic Lupus Erythematosus

Search GEO for disease gene expression data for Neonatal Systemic Lupus Erythematosus.

Pathways for Neonatal Systemic Lupus Erythematosus

GO Terms for Neonatal Systemic Lupus Erythematosus

Sources for Neonatal Systemic Lupus Erythematosus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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