MCID: NPH006
MIFTS: 24

Nephrogenic Adenofibroma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Nephrogenic Adenofibroma

MalaCards integrated aliases for Nephrogenic Adenofibroma:

Name: Nephrogenic Adenofibroma 12 15 70
Metanephric Adenofibroma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2698
NCIt 50 C39812
SNOMED-CT 67 128760004
UMLS 70 C1266141

Summaries for Nephrogenic Adenofibroma

MalaCards based summary : Nephrogenic Adenofibroma, also known as metanephric adenofibroma, is related to nephroma and metanephric adenoma. An important gene associated with Nephrogenic Adenofibroma is MAF (MAF BZIP Transcription Factor), and among its related pathways/superpathways are Transcriptional misregulation in cancer and C-MYB transcription factor network. Affiliated tissues include breast, kidney and cortex.

Related Diseases for Nephrogenic Adenofibroma

Diseases related to Nephrogenic Adenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 127)
# Related Disease Score Top Affiliating Genes
1 nephroma 30.4 WT1 TFE3
2 metanephric adenoma 30.2 WT1 KRT7 B3GAT1
3 epithelial predominant wilms' tumor 29.5 WT1 PRCC KRT7 B3GAT1
4 renal cell carcinoma, nonpapillary 29.4 WT1 TFE3 PRCC KRT7
5 wilms tumor 1 29.3 WT1 KRT7 CD34
6 renal cell carcinoma, papillary, 1 29.3 WT1 TFE3 PRCC KRT7 B3GAT1
7 adenofibroma 10.3
8 chromophil renal cell carcinoma 10.2
9 nivelon-nivelon-mabille syndrome 10.2 WT1 MAF
10 microinvasive cervical squamous cell carcinoma 10.2 WT1 KRT7
11 ovarian seromucinous carcinoma 10.2 WT1 KRT7
12 epididymal neoplasm 10.2 WT1 KRT7
13 ovarian large-cell neuroendocrine carcinoma 10.2 WT1 KRT7
14 wolffian duct adenocarcinoma 10.2 WT1 KRT7
15 pericardium cancer 10.2 WT1 KRT7
16 cystadenofibroma 10.2 WT1 KRT7
17 ovarian brenner tumor 10.2 WT1 KRT7
18 bladder clear cell adenocarcinoma 10.2 WT1 KRT7
19 middle ear carcinoma 10.2 WT1 KRT7
20 endosalpingiosis 10.2 WT1 KRT7
21 ovarian sex-cord stromal tumor 10.2 WT1 KRT7
22 breast osteosarcoma 10.2 WT1 KRT7
23 peritoneal serous adenocarcinoma 10.1 WT1 KRT7
24 epididymis adenocarcinoma 10.1 WT1 KRT7
25 epididymis cancer 10.1 WT1 KRT7
26 corneal dystrophy, posterior polymorphous, 4 10.1 MAF KRT7
27 kidney cortex disease 10.1 WT1 KRT7
28 ovarian benign neoplasm 10.1 WT1 KRT7
29 seminal vesicle adenocarcinoma 10.1 WT1 KRT7
30 ovarian endometrial cancer 10.1 WT1 KRT7
31 adenomatoid tumor 10.1 WT1 KRT7
32 female reproductive endometrioid cancer 10.1 WT1 KRT7
33 eosinophilic variant of chromophobe renal cell carcinoma 10.1 TFE3 KRT7
34 peritoneum cancer 10.1 WT1 KRT7
35 papillary serous adenocarcinoma 10.1 WT1 KRT7
36 clear cell papillary renal cell carcinoma 10.1 TFE3 KRT7
37 chromophil adenoma of the kidney 10.1 TFE3 KRT7
38 angiomyolipoma 10.1 TFE3 KRT7
39 uterus perivascular epithelioid cell tumor 10.1 TFE3 KRT7
40 sertoli-leydig cell tumor 10.1 WT1 KRT7
41 sex cord-gonadal stromal tumor 10.1 WT1 KRT7
42 papillary adenoma 10.1 TFE3 KRT7
43 adenocarcinoma in situ 10.1 WT1 KRT7
44 angiodysplasia 10.1
45 rare tumor 10.1
46 sertoli cell tumor 10.1 WT1 KRT7
47 renal cell carcinoma, xp11-associated 10.1 TFE3 PRCC
48 benign mesothelioma 10.1 WT1 KRT7
49 childhood kidney cell carcinoma 10.1 TFE3 PRCC
50 dysgerminoma 10.1 WT1 KRT7

Graphical network of the top 20 diseases related to Nephrogenic Adenofibroma:



Diseases related to Nephrogenic Adenofibroma

Symptoms & Phenotypes for Nephrogenic Adenofibroma

Drugs & Therapeutics for Nephrogenic Adenofibroma

Search Clinical Trials , NIH Clinical Center for Nephrogenic Adenofibroma

Genetic Tests for Nephrogenic Adenofibroma

Anatomical Context for Nephrogenic Adenofibroma

MalaCards organs/tissues related to Nephrogenic Adenofibroma:

40
Breast, Kidney, Cortex, Skeletal Muscle, Colon, Liver, Lung

Publications for Nephrogenic Adenofibroma

Articles related to Nephrogenic Adenofibroma:

(show all 31)
# Title Authors PMID Year
1
An "accidental" discovery: Incidentally found metanephric adenofibroma in a 5-year-old male trauma patient. 61
30026886 2018
2
Metanephric Adenofibroma In A Young Adult. 61
27802007 2017
3
BRAF exon 15 mutations in pediatric renal stromal tumors: prevalence in metanephric stromal tumors. 61
27769870 2017
4
Metanephric Adenofibroma Masquerading as Wilms' Tumor. 61
27900278 2016
5
Application of BRAF V600E mutation analysis for the diagnosis of metanephric adenofibroma. 61
26274032 2015
6
BRAF mutations in pediatric metanephric tumors. 61
26014474 2015
7
Metanephric adenofibroma in a 10-year-old boy: report of a case and review of the literature. 61
26045848 2015
8
Metanephric adenosarcoma: a rare case with immunohistochemistry and molecular analysis. 61
25267074 2014
9
Metanephric stromal tumor with unusual heterologous adipose differentiation: a case report and literature review. 61
24511729 2013
10
Metanephric adenofibroma. 61
23587517 2013
11
A composite renal tumor: metanephric adenofibroma, Wilms tumor, and renal cell carcinoma: a missing link? 61
21711207 2012
12
Metanephric stromal tumor arising in a patient with neurofibromatosis type 1 syndrome. 61
19875383 2011
13
Metanephric adenofibroma: robotic partial nephrectomy of a large Wilms' tumor variant. 61
20735912 2010
14
Multifocal metanephric adenoma in childhood. 61
19121092 2009
15
[Renal tumours of childhood: the last 100 years and where to from here]. 61
18924485 2008
16
Correlation of radiological and clinical features of metanephric neoplasms in adults. 61
15105578 2004
17
Myoid differentiation in mesoblastic nephroma: clinicopathologic and cytogenetic findings of a rare case. 61
12149722 2002
18
Metanephric adenosarcoma in a young adult: morphologic, immunophenotypic, ultrastructural, and fluorescence in situ hybridization analyses: a case report and review of the literature. 61
11684965 2001
19
Metastatic metanephric adenoma with foci of papillary carcinoma in a child: a combined histologic, immunohistochemical, and FISH study. 61
11584324 2001
20
The spectrum of metanephric adenofibroma and related lesions: clinicopathologic study of 25 cases from the National Wilms Tumor Study Group Pathology Center. 61
11257617 2001
21
Metanephric stromal tumor: report of 31 cases of a distinctive pediatric renal neoplasm. 61
10895814 2000
22
Adult mesoblastic nephroma. 61
10707372 2000
23
Adult mesoblastic nephroma with ciliated epithelium. A case report. 61
10782471 2000
24
Benign tumors and tumor-like lesions of the adult kidney. Part II: Benign mesenchymal and mixed neoplasms, and tumor-like lesions. 61
10640201 2000
25
Nephrogenic adenofibroma in a young child. 61
11156329 2000
26
Metanephric adenofibroma: report of a case and review of the literature. 61
10366157 1999
27
Papillary and metanephric adenomas of the kidney. 61
9503505 1998
28
Benign mixed epithelial and stromal tumor of the kidney. 61
9689654 1998
29
Nephrogenic adenofibroma: an unusual renal tumor. 61
9112535 1997
30
Benign adenomatous kidney neoplasms in children with polycythemia: imaging findings. 61
8539391 1996
31
Nephrogenic adenofibroma. A novel kidney tumor of young people. 61
1373578 1992

Variations for Nephrogenic Adenofibroma

Expression for Nephrogenic Adenofibroma

Search GEO for disease gene expression data for Nephrogenic Adenofibroma.

Pathways for Nephrogenic Adenofibroma

Pathways related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.21 WT1 TFE3 PRCC MAF
2 11.05 MAF CD34
3 10.79 TFE3 PRCC

GO Terms for Nephrogenic Adenofibroma

Biological processes related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 8.8 WT1 MAF CD34

Molecular functions related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 8.8 WT1 TFE3 MAF

Sources for Nephrogenic Adenofibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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