MCID: NPH001
MIFTS: 34

Nephrogenic Adenoma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Nephrogenic Adenoma

MalaCards integrated aliases for Nephrogenic Adenoma:

Name: Nephrogenic Adenoma 12 15
Nephrogenic Metaplasia 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7334
NCIt 50 C7413 C97097
SNOMED-CT 68 78236000
UMLS 73 C0334039

Summaries for Nephrogenic Adenoma

MalaCards based summary : Nephrogenic Adenoma, also known as nephrogenic metaplasia, is related to nephrogenic adenoma of urinary bladder and bladder diverticulum. An important gene associated with Nephrogenic Adenoma is AMACR (Alpha-Methylacyl-CoA Racemase), and among its related pathways/superpathways are Endometrial cancer and Pathways in cancer. Affiliated tissues include prostate, kidney and ovary.

Wikipedia : 76 Nephrogenic adenoma, also mesonephric adenoma and nephrogenic metaplasia, is a benign growth typically... more...

Related Diseases for Nephrogenic Adenoma

Diseases related to Nephrogenic Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)
# Related Disease Score Top Affiliating Genes
1 nephrogenic adenoma of urinary bladder 33.4 KRT7 PAX2 PAX8
2 bladder diverticulum 30.2 AMACR PAX2
3 papillary adenoma 29.9 AMACR KRT7
4 urethral diverticulum 29.6 AMACR KLK3 KRT7 NKX3-1 PAX8
5 suppression of tumorigenicity 12 29.5 AMACR KLK3 NKX3-1
6 clear cell adenocarcinoma 29.5 AMACR KLK3 KRT7 PAX2 PAX8
7 nephrogenic adenoma of the urethra 12.4
8 adenoma 11.0
9 adenocarcinoma 10.4
10 cystitis 10.1
11 rete testis adenoma 10.1 PAX2 PAX8
12 childhood endodermal sinus tumor 10.1 PAX2 PAX8
13 renal adenoma 10.1 AMACR KRT7
14 clear cell papillary renal cell carcinoma 10.1 AMACR KRT7
15 epithelial predominant wilms' tumor 10.1 AMACR KRT7
16 ovarian mucinous adenocarcinoma 10.0 AMACR KRT7
17 metanephric adenoma 10.0 AMACR KRT7
18 prune belly syndrome 10.0
19 transitional cell carcinoma 10.0
20 bladder urothelial carcinoma 10.0
21 cytomegalovirus infection 10.0
22 retinal hemangioblastoma 10.0 PAX2 PAX8
23 endosalpingiosis 10.0 KRT7 PAX8
24 renal pelvis adenocarcinoma 10.0 KRT7 PAX8
25 sensory organ benign neoplasm 10.0 KRT7 PAX8
26 deafness, autosomal dominant 10 10.0 PAX2 PAX8
27 mucinous tubular and spindle renal cell carcinoma 10.0 AMACR KRT7
28 endocervical carcinoma 10.0 KRT7 PAX8
29 renal pelvis carcinoma 10.0 KRT7 PAX8
30 spindle cell carcinoma 10.0 AMACR KRT7
31 peritoneum cancer 10.0 KRT7 PAX8
32 urethra adenocarcinoma 10.0 AMACR KLK3
33 cervical adenosquamous carcinoma 10.0 KRT7 PAX8
34 urethra clear cell adenocarcinoma 10.0 AMACR KLK3
35 urethral benign neoplasm 10.0 AMACR KLK3
36 prostate small cell carcinoma 10.0 AMACR KLK3
37 prostate sarcoma 9.9 KLK3 NKX3-1
38 oncocytoma 9.9 AMACR KRT7
39 ovarian cancer 1 9.9 KRT7 PAX8
40 malignant ovarian surface epithelial-stromal neoplasm 9.9 KRT7 PAX8
41 seminal vesicle adenocarcinoma 9.9 KLK3 KRT7
42 ovary epithelial cancer 9.9 KRT7 PAX8
43 seminal vesicle tumor 9.9 KLK3 KRT7
44 familial mediterranean fever 9.9
45 neuroblastoma 9.9
46 exstrophy of bladder 9.9
47 prostatic hypertrophy 9.9
48 interstitial cystitis 9.9
49 glandular cystitis 9.9
50 mucinous adenocarcinoma 9.9

Graphical network of the top 20 diseases related to Nephrogenic Adenoma:



Diseases related to Nephrogenic Adenoma

Symptoms & Phenotypes for Nephrogenic Adenoma

Drugs & Therapeutics for Nephrogenic Adenoma

Search Clinical Trials , NIH Clinical Center for Nephrogenic Adenoma

Genetic Tests for Nephrogenic Adenoma

Anatomical Context for Nephrogenic Adenoma

MalaCards organs/tissues related to Nephrogenic Adenoma:

41
Prostate, Kidney, Ovary, Testis, Thymus

Publications for Nephrogenic Adenoma

Articles related to Nephrogenic Adenoma:

(show top 50) (show all 193)
# Title Authors Year
1
Nephrogenic Adenoma in the Setting of Refractory Labial Agglutination in an Elderly Woman. ( 29489552 )
2018
2
Nephrogenic adenoma of the bladder: a single institution experience assessing clinical factors. ( 29493186 )
2018
3
Ureteral Nephrogenic Adenoma in Chronic Recreational Ketamine Abuse. ( 29204356 )
2018
4
Fibromyxoid Nephrogenic Adenoma in the Ureter. ( 29984315 )
2018
5
Nephrogenic Adenoma Complicating Renal Transplantation: A Case Report and Discussion. ( 29198684 )
2017
6
Nephrogenic adenoma does not express NKX3.1. ( 28581204 )
2017
7
Nephrogenic adenoma of the urinary tract: A 6-year single center experience. ( 28554748 )
2017
8
Nephrogenic adenoma in elderly patients: Three case reports. ( 27446559 )
2016
9
Nephrogenic adenoma arising in a complex circumferential urethral diverticulum of a female patient with a history of childhood neuroblastoma and chemotherapy. ( 27324755 )
2016
10
Nephrogenic Adenoma: Clinical Features, Management, and Diagnostic Pitfalls. ( 27138263 )
2016
11
Nephrogenic Adenoma of Female Urethra. ( 27172117 )
2016
12
Can We Identify Nephrogenic Adenoma in Urine Cytology Specimens? A Study Evaluating Previously Described Cytomorphologic Features in Correlation With PAX8 Immunohistochemical Staining Results. ( 27124920 )
2016
13
First-ever Reported Obstructing Ureteral Nephrogenic Adenoma in a Child and Subsequent Robotic-assisted Laparoscopic Ileal Ureter. ( 27001506 )
2016
14
Recurrence of childhood nephrogenic adenoma in urinary bladder developed four years after previous surgery despite intravesical sodium hyaluronate therapy. ( 27909627 )
2016
15
Fibromyxoid nephrogenic adenoma protruding in a renal cortical cyst. A rare morphological variant in an outstanding location. ( 26706600 )
2016
16
Diffuse and multifocal nephrogenic adenoma with Familial Mediterranean Fever: a case report with molecular study. ( 26428868 )
2015
17
BK polyomavirus-infected nephrogenic adenoma of the urinary bladder in a renal transplant recipient: A case report. ( 26189101 )
2015
18
Nephrogenic Adenoma of the Urinary Bladder: A Review of the Literature. ( 27347540 )
2015
19
Nephrogenic adenoma of the pediatric ureter. ( 25598138 )
2015
20
Nephrogenic adenoma of the urinary bladder: a report of three cases and a review of the literature. ( 24686831 )
2014
21
Nephrogenic adenoma of the urethra presenting as hematuria. ( 25177122 )
2014
22
Nephrogenic adenoma in a urethral diverticulum. ( 25185615 )
2014
23
Nephrogenic adenoma of the bladder associated with urinary tuberculosis. ( 25867159 )
2014
24
Immunohistochemical Staining Characteristics of Nephrogenic Adenoma Using the PIN-4 Cocktail (p63, AMACR, and CK903) and GATA-3. ( 24921643 )
2014
25
Rare cause of macroscopic hematuria in a pediatric patient: nephrogenic adenoma of the bladder. ( 25252049 )
2014
26
Nephrogenic adenoma of the urinary tract: clinical, histological, and immunohistochemical characteristics. ( 24142157 )
2013
27
Nephrogenic adenoma: a report of 3 unusual cases infiltrating into perinephric adipose tissue. ( 23426119 )
2013
28
Successful minimally-invasive management of a case of giant prostatic hypertrophy associated with recurrent nephrogenic adenoma of the prostate. ( 23565707 )
2013
29
Recurrent nephrogenic adenoma: a case report of resolution after treatment with antibiotics and nonsteroidal anti-inflammatory medication. ( 23791211 )
2013
30
Flat pattern of nephrogenic adenoma: previously unrecognized pattern unveiled using PAX2 and PAX8 immunohistochemistry. ( 23328975 )
2013
31
Recurrent nephrogenic adenoma in bladder diverticulum: Case report and literature review. ( 22511428 )
2012
32
Nephrogenic adenoma of the ureter. ( 22826785 )
2012
33
Nephrogenic adenoma of the urinary tract: a review. ( 22415059 )
2012
34
Multifocal nephrogenic adenoma a89 a mimicker of malignancy. ( 22294274 )
2012
35
Nephrogenic adenoma in a urethral diverticulum. ( 22673545 )
2012
36
Nephrogenic adenoma: an immunohistochemical analysis using biotin-free methods. ( 22495376 )
2012
37
Immunohistochemistery study in a case of nephrogenic adenoma of bladder. ( 23115444 )
2012
38
Ureteric nephrogenic adenoma: a report of two cases. ( 22771658 )
2012
39
The progression of nephrogenic metaplasia of the urinary bladder to clear cell adenocarcinoma: a case report. ( 24917724 )
2012
40
Vesical nephrogenic adenoma: an unusual presentation of a bladder tumour. ( 21989174 )
2011
41
Prostatic nephrogenic adenoma. Case report. ( 21705821 )
2011
42
Nephrogenic adenoma in the augmented bladder. ( 21862049 )
2011
43
Eosinophilic cystitis and nephrogenic adenoma of the bladder: a rare association of 2 unusual findings in childhood. ( 21496523 )
2011
44
A rare presentation of nephrogenic adenoma: multiple upper tract lesions in a female patient. ( 22166337 )
2011
45
Nephrogenic adenoma of the bladder in a prune belly syndrome patient: case report and review of the literature. ( 21843046 )
2011
46
Nephrogenic adenoma of the bladder. ( 21030051 )
2010
47
Nephrogenic adenoma. ( 20619548 )
2010
48
Clear cell adenocarcinoma of the bladder and urethra: cases diffusely mimicking nephrogenic adenoma. ( 20060152 )
2010
49
Multifocal nephrogenic adenoma of the bladder in a pediatric patient. ( 20660459 )
2010
50
Nephrogenic adenoma: report of a case and review of morphologic mimics. ( 20923300 )
2010

Variations for Nephrogenic Adenoma

Expression for Nephrogenic Adenoma

Search GEO for disease gene expression data for Nephrogenic Adenoma.

Pathways for Nephrogenic Adenoma

GO Terms for Nephrogenic Adenoma

Biological processes related to Nephrogenic Adenoma according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 9.77 NKX3-1 PAX2 PAX8
2 inner ear morphogenesis GO:0042472 9.59 PAX2 PAX8
3 branching involved in ureteric bud morphogenesis GO:0001658 9.58 PAX2 PAX8
4 protein kinase B signaling GO:0043491 9.58 NKX3-1 PAX2
5 metanephros development GO:0001656 9.57 NKX3-1 PAX8
6 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.56 PAX2 PAX8
7 mesonephros development GO:0001823 9.55 PAX2 PAX8
8 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.54 PAX2 PAX8
9 pronephros development GO:0048793 9.52 PAX2 PAX8
10 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.51 PAX2 PAX8
11 metanephric epithelium development GO:0072207 9.49 PAX2 PAX8
12 metanephric distal convoluted tubule development GO:0072221 9.48 PAX2 PAX8
13 metanephric nephron tubule formation GO:0072289 9.46 PAX2 PAX8
14 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.43 PAX2 PAX8
15 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.4 PAX2 PAX8
16 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.37 PAX2 PAX8
17 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.32 PAX2 PAX8
18 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.26 PAX2 PAX8
19 positive regulation of metanephric DCT cell differentiation GO:2000594 9.16 PAX2 PAX8
20 pronephric field specification GO:0039003 8.96 PAX2 PAX8
21 urogenital system development GO:0001655 8.8 NKX3-1 PAX2 PAX8

Molecular functions related to Nephrogenic Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription regulatory region DNA binding GO:0044212 8.8 NKX3-1 PAX2 PAX8

Sources for Nephrogenic Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
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32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
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38 LifeMap
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45 MESH via Orphanet
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49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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