MCID: NPH008
MIFTS: 25

Nephrogenic Adenoma of the Urethra

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Nephrogenic Adenoma of the Urethra

MalaCards integrated aliases for Nephrogenic Adenoma of the Urethra:

Name: Nephrogenic Adenoma of the Urethra 12 15
Nephrogenic Adenoma of Urethra 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8109
NCIt 50 C7416
UMLS 70 C1336889

Summaries for Nephrogenic Adenoma of the Urethra

MalaCards based summary : Nephrogenic Adenoma of the Urethra, also known as nephrogenic adenoma of urethra, is related to nephrogenic adenoma and clear cell adenocarcinoma. An important gene associated with Nephrogenic Adenoma of the Urethra is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways is ID signaling pathway. Affiliated tissues include breast, kidney and prostate.

Related Diseases for Nephrogenic Adenoma of the Urethra

Diseases related to Nephrogenic Adenoma of the Urethra via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 286)
# Related Disease Score Top Affiliating Genes
1 nephrogenic adenoma 30.2 PAX8 PAX2 KRT7 KLK3 AMACR
2 clear cell adenocarcinoma 29.1 PAX8 PAX2 KRT7 KRT20 KLK3 AMACR
3 urethra adenocarcinoma 10.4 KLK3 AMACR
4 urethra cancer 10.3 KLK3 AMACR
5 prostatic hyperplasia, benign 10.3 KLK3 ACP3
6 adenoma 10.3
7 ureterocele 10.2 PAX8 PAX2
8 prostatic adenoma 10.2 KLK3 ACP3
9 prostate lymphoma 10.2 MME KLK3
10 cervix endometriosis 10.2 PAX2 MME
11 thyroid sarcoma 10.2 THBD PAX8
12 bladder lymphoma 10.2 MME KRT20
13 urethral syndrome 10.2 KRT20 KLK3 AMACR
14 prostatic acinar adenocarcinoma 10.2 PAX8 KLK3 AMACR
15 lymphohistiocytoid mesothelioma 10.2 THBD CALB2
16 lung sarcomatoid carcinoma 10.2 THBD CALB2
17 cervical carcinosarcoma 10.2 MME CALB2
18 pacinian tumor 10.2 MME CALB2
19 acute cystitis 10.2
20 ovarian mixed germ cell neoplasm 10.1 PAX8 MME
21 thymus adenocarcinoma 10.1 KRT5 KRT20
22 thymus basaloid carcinoma 10.1 PAX8 KRT5
23 ovarian endometrioid stromal sarcoma 10.1 MME CALB2
24 colon leiomyosarcoma 10.1 PAX8 KRT5
25 papillorenal syndrome 10.1 PAX8 PAX2
26 spindle cell thymoma 10.1 KRT5 CALB2
27 rete testis adenoma 10.1 PAX8 PAX2 CALB2
28 ovary sarcoma 10.1 MME CALB2
29 testicular fibroma 10.1 KRT5 CALB2
30 gray zone lymphoma 10.1 MME FUT4
31 bile duct adenoma 10.1 KRT7 KRT20
32 epithelial predominant wilms' tumor 10.1 KRT7 AMACR
33 male urethral cancer 10.0 KRT5 KLK3 AMACR
34 cervix erosion 10.0 MME KRT5
35 thyroid angiosarcoma 10.0 THBD PAX8 KRT20
36 sarcomatoid mesothelioma 10.0 THBD CALB2
37 urethral villous adenoma 10.0 KRT7 KRT20
38 prostate transitional cell carcinoma 10.0 KRT5 KLK3 AMACR
39 composite lymphoma 10.0 MME FUT4
40 atrophic vulva 10.0 KRT7 KRT20
41 micronodular basal cell carcinoma 10.0 MME KRT5
42 urinary bladder villous adenoma 10.0 KRT7 KRT20
43 vulva adenocarcinoma 10.0 KRT7 KRT20
44 heart cancer 10.0 KRT5 CALB2
45 vaginal tubulovillous adenoma 10.0 KRT7 KRT20
46 mucinous ovarian cystadenoma 10.0 KRT7 KRT20
47 rectosigmoid junction neoplasm 10.0 KRT7 KRT20
48 transverse colon cancer 10.0 KRT7 KRT20
49 sigmoid neoplasm 10.0 KRT7 KRT20
50 urinary bladder small cell neuroendocrine carcinoma 10.0 KRT7 KRT20

Graphical network of the top 20 diseases related to Nephrogenic Adenoma of the Urethra:



Diseases related to Nephrogenic Adenoma of the Urethra

Symptoms & Phenotypes for Nephrogenic Adenoma of the Urethra

Drugs & Therapeutics for Nephrogenic Adenoma of the Urethra

Search Clinical Trials , NIH Clinical Center for Nephrogenic Adenoma of the Urethra

Genetic Tests for Nephrogenic Adenoma of the Urethra

Anatomical Context for Nephrogenic Adenoma of the Urethra

MalaCards organs/tissues related to Nephrogenic Adenoma of the Urethra:

40
Breast, Kidney, Prostate, Thymus, Liver, Lung, Thyroid

Publications for Nephrogenic Adenoma of the Urethra

Articles related to Nephrogenic Adenoma of the Urethra:

# Title Authors PMID Year
1
Nephrogenic adenoma of the urethra presenting as hematuria. 61
25177122 2014
2
A case series of nephrogenic adenoma of the urethra and bladder in children: review of this rare diagnosis, its natural history and management, with reference to the literature. 61
18947630 2006
3
[Nephrogenic adenoma of the urethra. Report of a case]. 61
14677362 2003
4
Nephrogenic adenoma of the urethra: an unusual cause of hematuria in the child. 61
12891515 2003
5
Nephrogenic adenoma mimicking carcinoma: a potential pitfall in cytodiagnosis. 61
10613974 2000
6
Clear cell adenocarcinoma and nephrogenic adenoma of the urethra and urinary bladder: a histopathologic and immunohistochemical comparison. 61
9865832 1998
7
Nephrogenic adenoma after urethral reconstruction using bladder mucosa: report of 6 cases and review of the literature. 61
9258165 1997
8
Nephrogenic adenoma of the urethra presenting as gross hematuria in a child. 61
9072630 1997

Variations for Nephrogenic Adenoma of the Urethra

Expression for Nephrogenic Adenoma of the Urethra

Search GEO for disease gene expression data for Nephrogenic Adenoma of the Urethra.

Pathways for Nephrogenic Adenoma of the Urethra

Pathways related to Nephrogenic Adenoma of the Urethra according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.83 PAX8 PAX2

GO Terms for Nephrogenic Adenoma of the Urethra

Cellular components related to Nephrogenic Adenoma of the Urethra according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.8 KRT7 KRT5 KRT20

Biological processes related to Nephrogenic Adenoma of the Urethra according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 keratinization GO:0031424 9.75 KRT7 KRT5 KRT20
2 cornification GO:0070268 9.72 KRT7 KRT5 KRT20
3 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.57 PAX8 PAX2
4 urogenital system development GO:0001655 9.56 PAX8 PAX2
5 mesonephros development GO:0001823 9.54 PAX8 PAX2
6 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.52 PAX8 PAX2
7 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.51 PAX8 PAX2
8 pronephros development GO:0048793 9.49 PAX8 PAX2
9 metanephric epithelium development GO:0072207 9.48 PAX8 PAX2
10 metanephric nephron tubule formation GO:0072289 9.46 PAX8 PAX2
11 metanephric distal convoluted tubule development GO:0072221 9.43 PAX8 PAX2
12 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.4 PAX8 PAX2
13 positive regulation of metanephric DCT cell differentiation GO:2000594 9.37 PAX8 PAX2
14 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.32 PAX8 PAX2
15 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.26 PAX8 PAX2
16 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.16 PAX8 PAX2
17 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 8.96 PAX8 PAX2
18 pronephric field specification GO:0039003 8.62 PAX8 PAX2

Sources for Nephrogenic Adenoma of the Urethra

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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