MCID: NRV004
MIFTS: 35

Nerve Compression Syndrome

Categories: Neuronal diseases

Aliases & Classifications for Nerve Compression Syndrome

MalaCards integrated aliases for Nerve Compression Syndrome:

Name: Nerve Compression Syndrome 12 15 73
Entrapment Neuropathies 55 73
Hereditary Liability to Pressure Palsies 73
Peripheral Nerve Entrapment Syndrome 12
Nerve Compression Syndromes 44
Compression Neuropathy 12
Entrapment Neuropathy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:573
MeSH 44 D009408
NCIt 50 C27221
SNOMED-CT 68 155085004 45781009

Summaries for Nerve Compression Syndrome

MalaCards based summary : Nerve Compression Syndrome, also known as entrapment neuropathies, is related to peripheral nervous system disease and neuropathy, hereditary, with liability to pressure palsies, and has symptoms including neuralgia An important gene associated with Nerve Compression Syndrome is PMP22 (Peripheral Myelin Protein 22). The drugs Lidocaine and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and liver.

Wikipedia : 76 Nerve compression syndrome or compression neuropathy, also known as entrapment neuropathy, is a medical... more...

Related Diseases for Nerve Compression Syndrome

Graphical network of the top 20 diseases related to Nerve Compression Syndrome:



Diseases related to Nerve Compression Syndrome

Symptoms & Phenotypes for Nerve Compression Syndrome

UMLS symptoms related to Nerve Compression Syndrome:


neuralgia

Drugs & Therapeutics for Nerve Compression Syndrome

Drugs for Nerve Compression Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 202)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 137-58-6 3676
2
Bupivacaine Approved, Investigational Phase 4,Not Applicable 2180-92-9, 38396-39-3 2474
3
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 50-24-8 5755
4
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 83-43-2 6741
5
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
6
Gabapentin Approved, Investigational Phase 4,Phase 3 60142-96-3 3446
7
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 124-94-7 31307
8
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
9
Ropivacaine Approved Phase 4,Not Applicable 84057-95-4 71273 175805
10
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
11
gamma-Aminobutyric acid Approved, Investigational Phase 4,Phase 3 56-12-2 119
12
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
13
Ibuprofen Approved Phase 4,Phase 2 15687-27-1 3672
14
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
15
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
16
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 2 76-42-6 5284603
17
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 11103-57-4, 68-26-8 445354
18
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3 59-30-3 6037
19 tannic acid Approved, Nutraceutical Phase 4
20 Prednisolone acetate Phase 4,Phase 2,Phase 3,Not Applicable
21 Analgesics Phase 4,Phase 3,Phase 2,Not Applicable
22 glucocorticoids Phase 4,Phase 3,Phase 2,Not Applicable
23 Respiratory System Agents Phase 4,Phase 3,Not Applicable
24 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
25 Methylprednisolone acetate Phase 4,Phase 2,Phase 3,Not Applicable
26 Methylprednisolone Hemisuccinate Phase 4,Phase 2,Phase 3,Not Applicable
27 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Not Applicable
28 Sodium Channel Blockers Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
29 Neuroprotective Agents Phase 4,Phase 2,Phase 3,Not Applicable
30 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
31 Analgesics, Non-Narcotic Phase 4,Phase 2,Not Applicable
32 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
33 Hormone Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
34 Anesthetics, Local Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
35 Tranquilizing Agents Phase 4,Phase 3,Phase 2,Not Applicable
36 Hormones Phase 4,Phase 3,Phase 2,Not Applicable
37 Diuretics, Potassium Sparing Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
39 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
40 Anti-Asthmatic Agents Phase 4,Phase 3,Not Applicable
41 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Anticonvulsants Phase 4,Phase 3,Not Applicable
43 Prednisolone hemisuccinate Phase 4,Phase 2,Phase 3,Not Applicable
44 Prednisolone phosphate Phase 4,Phase 2,Phase 3,Not Applicable
45 Antiemetics Phase 4,Phase 2,Phase 3,Not Applicable
46 Protective Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
47 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable
48 Psychotropic Drugs Phase 4,Phase 3,Phase 2,Not Applicable
49 Antimanic Agents Phase 4,Phase 3,Not Applicable
50 Autonomic Agents Phase 4,Phase 2,Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 267)
# Name Status NCT ID Phase Drugs
1 Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial. Completed NCT01895621 Phase 4
2 Local Steroid Injection vs Placebo in Carpal Tunnel Syndrome Completed NCT02652390 Phase 4 Methylprednisolone 80 mg;Methylprednisolone 40 mg
3 Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries Completed NCT02313675 Phase 4 Acetaminophen;Ketorolac Tromethamine;Saline
4 Efficacy Study of Local Steroid Injection and Wrist Splinting for Carpal Tunnel Syndrome Completed NCT02140632 Phase 4
5 Bupivacaine Versus Lidocaine Local Anesthesia Completed NCT01751347 Phase 4 Bupivacaine;Lidocaine
6 Length of Post Operative Dressing After Carpal Tunnel Release Completed NCT01310218 Phase 4
7 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
8 Patient Controlled Regional Analgesia Following Carpal Tunnel Release: A Double-Blind Study Using Distal Perineural Catheters Completed NCT00678314 Phase 4 Ropivacaine 0.2%;Ropivacaine 0.75%;Normal saline
9 Therapeutic Effects Analysis of Pudendal Nerve Infiltrations After 3 Months, in Patients Suffering of Pudendal Neuralgia Completed NCT00851513 Phase 4 Lidocaine;Depmedrol
10 Short and Long Term Exposure to Unique, Time-Varying Pulsed Electro-Magnetic Fields in Refractory Carpal Tunnel Syndrome Completed NCT00277563 Phase 4
11 Narcotic vs. Non-narcotic Pain Study Protocol Recruiting NCT01974609 Phase 4 Narcotic;non-narcotic
12 Non-surgical Treatment of Carpal Tunnel Syndrome: Night Splint Versus Local Corticosteroid Infiltration Active, not recruiting NCT03196817 Phase 4 betamethasone dipropionate, betamethasone disodium phosphate and lidocaine 2%
13 Injection Versus Splinting in Carpal Tunnel Syndrome Active, not recruiting NCT02038452 Phase 4 Depo-Medrone
14 Post-operative Analgesia in Elective, Soft-tissue Hand Surgery Enrolling by invitation NCT02029235 Phase 4 Acetaminophen/Hydrocodone;Acetaminophen/Ibuprofen
15 Preoperative Antibiotics for Carpal Tunnel Release Surgery Not yet recruiting NCT03432858 Phase 4 Vancomycin;Cefazolin;Saline Solution
16 Patient Satisfaction With Pain Relief After Ambulatory Hand Surgery Terminated NCT01588158 Phase 4 Acetaminophen;Vicodin
17 Lidocaine and Triamcinolone vs Saline Trigger Point Injection for Treatment of Chronic Abdominal Wall Pain Withdrawn NCT02748395 Phase 4 Triamcinolone;Lidocaine
18 Treadmill, Stretching and Proprioceptive Exercise (TreSPE) Rehabilitation Program for Charcot−Marie−Tooth Neuropathy Type 1A (CMT1A) Unknown status NCT01289704 Phase 2, Phase 3
19 Carpal Tunnel Syndrome Release Using PSU Retractor Unknown status NCT01017471 Phase 3
20 High Dose Ascorbic Acid Treatment of CMT1A Completed NCT00484510 Phase 2, Phase 3 Ascorbic acid (Vitamin C);placebo
21 Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome Completed NCT02141035 Phase 2, Phase 3 Acetyl-l-carnitine;placebo
22 Sonographic Examination Cubital Tunnel Release Completed NCT02739945 Phase 3
23 Sonography-guided Steroid Injection for Carpal Tunnel Syndrome Completed NCT02575729 Phase 3 betamethasone
24 Preoperative Gabapentine for Carpal Tunnel Completed NCT01632215 Phase 3 Gabapentine
25 Steroid Injection Treatment of Carpal Tunnel Syndrome Completed NCT00806871 Phase 2, Phase 3 Methylprednisolone 40 mg;Methylprednisolone 80 mg;Sodium chloride
26 Gabapentin for Carpal Tunnel Syndrome Completed NCT00137735 Phase 3 Gabapentin
27 Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia Completed NCT02604186 Phase 2, Phase 3
28 Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acid Completed NCT00007020 Phase 3 Cholic Acids
29 Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A Recruiting NCT03023540 Phase 3 PXT3003
30 Setmelanotide Phase 2 Treatment Trial in Patients With Rare Genetic Disorders of Obesity Recruiting NCT03013543 Phase 2, Phase 3 Setmelanotide
31 Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT) Active, not recruiting NCT02579759 Phase 3 PXT3003 dose 1;PXT3003 dose 2;placebo
32 Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome Enrolling by invitation NCT03184584 Phase 2, Phase 3 PBI-4050
33 Assessment of the Effectiveness of Ultrasound-guided Acupuncture in the Management of Carpal Tunnel Syndrome Not yet recruiting NCT02870673 Phase 2, Phase 3 SHINCORT;XYLOCAINE
34 Erythropoietin Spinal Cord Compression Randomized Trial Terminated NCT00220675 Phase 2, Phase 3 Erythropoietin infusion
35 NeuroPath Comparative Validation Study Plan Terminated NCT00393549 Phase 3
36 A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Minor Surgical Procedures Terminated NCT00209560 Phase 3 fospropofol disodium
37 Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome Terminated NCT00266214 Phase 3 lidocaine patch 5%
38 Carpal Tunnel Syndrome and Static Magnetic Field Therapy Unknown status NCT00521495 Phase 2
39 Carpal Tunnel Syndrome Treated With 830nm Diode Laser Unknown status NCT00514462 Phase 1, Phase 2
40 Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease Completed NCT00541164 Phase 1, Phase 2 Coenzyme Q10
41 Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease Completed NCT02561702 Phase 2 Mexiletine
42 Phase II, Randomized, Placebo-controlled Trial in Patients With Charcot-marie-tooth Disease Type 1A Completed NCT01401257 Phase 2 PXT3003 Low dose;PXT3003 Intermediate Dose;PXT3003 High Dose
43 Ascorbic Acid Treatment in CMT1A Trial (AATIC) Completed NCT00271635 Phase 2 Placebo;ascorbic acid
44 The Treatment of the Median Nerve for the Elimination of the Symptoms Associated With the Carpal Tunnel Syndrome Completed NCT00634738 Phase 1, Phase 2
45 L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1 Completed NCT01733407 Phase 1, Phase 2 L-serine;placebo
46 Comparison of Effect of Anterior Subcutaneous and Submuscular Transposition on Cubital Tunnel Syndrome Completed NCT01109901 Phase 2
47 A Pilot Study to Evaluate the Effectiveness of Ultrasound Guided Looped Thread Carpal Tunnel Release Completed NCT03476486 Phase 2
48 Treatment of Thoracic Outlet Syndrome (TOS) With Botox Completed NCT00444886 Phase 2 Botulinum Toxin Type A injection (BOTOX);Botulinum Toxin Type A injection (BOTOX)
49 Percutaneous Treatment of Carpal Tunnel Syndrome With Scan Completed NCT02514317 Phase 2
50 Fascial Manipulation on the Treatment of Carpal Tunnel Syndrome Completed NCT02495298 Phase 2

Search NIH Clinical Center for Nerve Compression Syndrome

Cochrane evidence based reviews: nerve compression syndromes

Genetic Tests for Nerve Compression Syndrome

Anatomical Context for Nerve Compression Syndrome

MalaCards organs/tissues related to Nerve Compression Syndrome:

41
Testes, Skin, Liver, Heart, Spinal Cord, Brain

Publications for Nerve Compression Syndrome

Articles related to Nerve Compression Syndrome:

(show all 24)
# Title Authors Year
1
Peripheral Neuropathy and Nerve Compression Syndromes in Burns. ( 28888304 )
2017
2
Redo Microvascular Decompression in a Patient of Resistant Cochleovestibular Nerve Compression Syndrome. ( 29114297 )
2017
3
Cochleovestibular nerve compression syndrome due to intrameatal Anterior Inferior Cerebellar Artery loop: synthesis of best evidence for clinical decisions. ( 27647022 )
2016
4
Resolution of intractable retching following mobilization of a dolichoectatic vertebral artery: case report of a unique brainstem-cranial nerve compression syndrome. ( 27767394 )
2016
5
Anterior interosseous nerve compression syndrome: is there a role for endoscopy? ( 21786008 )
2011
6
Hypertrophic abductor hallucis muscle with nerve compression syndrome. ( 21381535 )
2010
7
Differential diagnosis of cervical nerve compression syndrome of the external intervertebral foramen. ( 24557672 )
2007
8
Unusual complication of an opposition tendon transfer at the wrist: ulnar nerve compression syndrome. ( 15249086 )
2004
9
Management of nerve compression syndrome in musicians. ( 12852670 )
2003
10
Bilateral radial nerve compression syndrome in an elite swimmer: a case report. ( 12130418 )
2002
11
Acute ulnar nerve compression syndrome in a powerlifter with triceps tendon rupture--a case report. ( 10853704 )
2000
12
Ulnar nerve compression syndrome due to an anomalous arch of the ulnar nerve piercing the flexor carpi ulnaris: a case report. ( 8683063 )
1996
13
Cochleovestibular nerve compression syndrome. I. Clinical features and audiovestibular findings. ( 1518347 )
1992
14
Cochleovestibular nerve compression syndrome. II. Vestibular nerve histopathology and theory of pathophysiology. ( 1518348 )
1992
15
Dorsal interrosseous nerve compression syndrome from the use of a Canadian crutch. ( 3237242 )
1988
16
Bilateral anomalous course of the ulnar nerve at the wrist causing ulnar and median nerve compression syndrome. Case report. ( 3668645 )
1987
17
Suprascapular nerve compression syndrome. ( 6463842 )
1984
18
Anterior interosseous nerve compression syndrome: from metastatic bronchogenic carcinoma to the forearm. ( 6622577 )
1983
19
Suprascapular nerve compression syndrome. ( 7432615 )
1980
20
Medial epicondylectomy for ulnar nerve compression syndrome at the elbow. ( 455838 )
1979
21
Femoral nerve compression syndrome with paresis of the quadriceps muscle caused by radiotherapy of malignant tumours. A report of four cases. ( 1199719 )
1975
22
[Rare location of an epidermoid cyst in the forefoot region with nerve compression syndrome. Contribution to the differential diagnosis of Morton's metatarsalgia (author's transl)]. ( 817145 )
1975
23
Radial palsy following muscular effort. A nerve compression syndrome possibly related to a fibrous arch of the lateral head of the triceps. ( 4327331 )
1971
24
Nerve compression syndrome in derangements of the proximal and distal radial ulnar joints. ( 4300971 )
1968

Variations for Nerve Compression Syndrome

Expression for Nerve Compression Syndrome

Search GEO for disease gene expression data for Nerve Compression Syndrome.

Pathways for Nerve Compression Syndrome

GO Terms for Nerve Compression Syndrome

Sources for Nerve Compression Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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