MCID: NRL001
MIFTS: 33

Neurilemmoma of the Fifth Cranial Nerve

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Neurilemmoma of the Fifth Cranial Nerve

MalaCards integrated aliases for Neurilemmoma of the Fifth Cranial Nerve:

Name: Neurilemmoma of the Fifth Cranial Nerve 12 15
Trigeminal Schwannoma 12 73
Trigeminal Neurilemmoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3202
NCIt 50 C4655
UMLS 73 C0349582

Summaries for Neurilemmoma of the Fifth Cranial Nerve

MalaCards based summary : Neurilemmoma of the Fifth Cranial Nerve, also known as trigeminal schwannoma, is related to neurilemmoma and obstructive hydrocephalus. An important gene associated with Neurilemmoma of the Fifth Cranial Nerve is SLC25A15 (Solute Carrier Family 25 Member 15), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include bone, prostate and brain, and related phenotypes are behavior/neurological and digestive/alimentary

Related Diseases for Neurilemmoma of the Fifth Cranial Nerve

Diseases related to Neurilemmoma of the Fifth Cranial Nerve via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 117)
# Related Disease Score Top Affiliating Genes
1 neurilemmoma 30.2 GFAP NF1 NF2 PRKAR1A
2 obstructive hydrocephalus 30.0 CRLF1 GFAP NF1
3 cerebral convexity meningioma 10.2 GFAP NF2
4 intraventricular meningioma 10.2 GFAP NF2
5 rhabdoid meningioma 10.2 GFAP NF2
6 spinal cancer 10.2 GFAP NF2
7 cornea cancer 10.2 GFAP NF2
8 neurofibromatosis, familial spinal 10.2 NF1 NF2
9 chordoid glioma 10.2 GFAP NF2
10 benign ependymoma 10.2 GFAP NF2
11 malignant ependymoma 10.2 GFAP NF2
12 anaplastic ependymoma 10.2 GFAP NF2
13 immature cataract 10.2 NF1 NF2
14 neurofibrosarcoma 10.2 NF1 NF2
15 tanycytic ependymoma 10.2 GFAP NF2
16 plexiform neurofibroma 10.2 NF1 NF2
17 amyloid tumor 10.2 NF1 NF2
18 gliofibroma 10.2 GFAP NF1
19 spinal meningioma 10.2 NF1 NF2
20 primitive neuroectodermal tumor of the cervix uteri 10.2 GFAP PTPRC
21 spinal canal and spinal cord meningioma 10.2 NF1 NF2
22 histiocytic and dendritic cell cancer 10.2 LYZ PTPRC
23 optic nerve neoplasm 10.2 NF1 NF2
24 pilocytic astrocytoma 10.2 GFAP NF1
25 acoustic neuroma 10.2 NF1 NF2
26 central nervous system sarcoma 10.2 CD68 LYZ
27 cardiomyopathy, infantile histiocytoid 10.2 CD68 LYZ
28 cogan syndrome 10.2 CRLF1 GFAP
29 adult xanthogranuloma 10.2 CD68 LYZ
30 pilomyxoid astrocytoma 10.2 GFAP NF1
31 liver sarcoma 10.1 CD68 LYZ
32 granulomatous myositis 10.1 CD68 LYZ
33 inflammatory mfh 10.1 CD68 GFAP
34 juvenile pilocytic astrocytoma 10.1 GFAP NF1
35 testis seminoma 10.1 GFAP PTPRC
36 inflammatory leiomyosarcoma 10.1 CD68 NF1
37 conventional leiomyosarcoma 10.1 CD68 NF1
38 brachial plexus lesion 10.1 CRLF1 NF1
39 nodular tenosynovitis 10.1 CD68 PTPRC
40 acute salpingitis 10.1 CD68 LYZ
41 extracutaneous mastocytoma 10.1 CD68 PTPRC
42 lymphatic system cancer 10.1 LYZ PTPRC
43 papillary ependymoma 10.1 CD68 GFAP
44 brain sarcoma 10.1 CD68 PTPRC
45 aleukemic leukemia cutis 10.1 CD68 LYZ
46 glomeruloid hemangioma 10.1 CD68 PTPRC
47 ulcerative stomatitis 10.1 CD68 LYZ
48 conventional fibrosarcoma 10.1 CD68 PTPRC
49 granular cell tumor 10.1 CD68 GFAP
50 hodgkin's lymphoma, lymphocytic depletion 10.1 CD68 PTPRC

Graphical network of the top 20 diseases related to Neurilemmoma of the Fifth Cranial Nerve:



Diseases related to Neurilemmoma of the Fifth Cranial Nerve

Symptoms & Phenotypes for Neurilemmoma of the Fifth Cranial Nerve

MGI Mouse Phenotypes related to Neurilemmoma of the Fifth Cranial Nerve:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.06 CRLF1 CYS1 GFAP LYZ NF1 NF2
2 digestive/alimentary MP:0005381 10.03 CYS1 GFAP LYZ NF1 NUMB PRKAR1A
3 homeostasis/metabolism MP:0005376 10.02 CYS1 GFAP LYZ NF1 NF2 NUMB
4 hematopoietic system MP:0005397 10.01 CD68 CRLF1 CYS1 LYZ NF1 NUMB
5 immune system MP:0005387 9.97 CD68 CYS1 GFAP LYZ NF1 NF2
6 mortality/aging MP:0010768 9.81 CRLF1 CYS1 GFAP LYZ NF1 NF2
7 liver/biliary system MP:0005370 9.73 CYS1 LYZ NF1 NF2 PRKAR1A PTPRC
8 neoplasm MP:0002006 9.35 LYZ NF1 NF2 PRKAR1A PTPRC
9 nervous system MP:0003631 9.23 CRLF1 CYS1 GFAP LYZ NF1 NF2

Drugs & Therapeutics for Neurilemmoma of the Fifth Cranial Nerve

Search Clinical Trials , NIH Clinical Center for Neurilemmoma of the Fifth Cranial Nerve

Genetic Tests for Neurilemmoma of the Fifth Cranial Nerve

Anatomical Context for Neurilemmoma of the Fifth Cranial Nerve

MalaCards organs/tissues related to Neurilemmoma of the Fifth Cranial Nerve:

41
Bone, Prostate, Brain, Liver, Spinal Cord, Cervix, Testis

Publications for Neurilemmoma of the Fifth Cranial Nerve

Articles related to Neurilemmoma of the Fifth Cranial Nerve:

(show top 50) (show all 75)
# Title Authors Year
1
Primary central nervous system lymphoma at the cerebellopontine angle mimicking a trigeminal schwannoma: A unique case report and literature review. ( 29656000 )
2018
2
Presigmoid Approach to Dumbbell Trigeminal Schwannoma. ( 30456036 )
2018
3
Retrosigmoid Approach to the Posterior Fossa Trigeminal Schwannoma. ( 30456037 )
2018
4
Single Stage Complete Removal of Dumbbell Trigeminal Schwannoma in a Child by Skull Base Approach. ( 29492145 )
2018
5
Trigeminal schwannoma presenting as a gelastic seizure: no laughing matter. ( 29688073 )
2018
6
Gamma knife radiosurgery for trigeminal schwannoma: a 20-year experience with long-term treatment outcome. ( 29931615 )
2018
7
Endoscopic Transvestibular Transmandibular Approach for Trigeminal Schwannoma in Infratemporal Fossa and Parapharyngeal Space. ( 30031184 )
2018
8
Neuroendoscopic Resection of Trigeminal Schwannoma in the Pterygopalatine/Infratemporal Fossa via the Transnasal Perpendicular Plate Palatine Bone or Transnasal Maxillary Sinus Approach. ( 30218796 )
2018
9
Syphilis mimicking trigeminal schwannoma. ( 28226086 )
2017
10
Trigeminal schwannoma. ( 29386819 )
2017
11
Cerebellopontine angle primitive neuroectodermal tumor mimicking trigeminal schwannoma. ( 26862446 )
2016
12
Rare case of radiation-induced trigeminal schwannoma occurring in a long-term glioblastoma multiforme survivor. ( 26969360 )
2016
13
Solid cystic trigeminal schwannoma with intraorbital extension causing proptosis and vision loss. ( 27695572 )
2016
14
Surgical Approach to the Cavernous Sinus for a Trigeminal Schwannoma Resection: Technical Note and Case Report. ( 27803834 )
2016
15
Denervation of the Eustachian Tube and Hearing Loss Following Trigeminal Schwannoma Resection. ( 26937336 )
2016
16
Erdheim-Chester disease mimicking an intracranial trigeminal schwannoma: case report. ( 25723722 )
2015
17
Gasserian ganglion neurosarcoidosis mimicking trigeminal schwannoma. ( 25742592 )
2015
18
Giant Trigeminal Schwannoma Presenting with Obstructive Hydrocephalus. ( 26719829 )
2015
19
Metastatic Renal Cell Carcinoma Mimicking Trigeminal Schwannoma in a Patient Presenting with Trigeminal Neuralgia. ( 26623243 )
2015
20
Primary non-hodgkin lymphoma of lateral skull base mimicking a trigeminal schwannoma: case report. ( 26309705 )
2015
21
Orbital extension of trigeminal schwannoma. ( 25552864 )
2015
22
Total removal of a trigeminal schwannoma via the expanded endoscopic endonasal approach. Technical note. ( 25845553 )
2015
23
Intracranial trigeminal schwannoma. ( 25924170 )
2015
24
A Rare Case of Hearing Impairment due to Cerebello-Pontine Angle Lesion: Trigeminal Schwannoma. ( 26381011 )
2015
25
Trigeminal schwannoma presenting as atypical trigeminal neuralgia and masseter atrophy. ( 24833215 )
2014
26
Trigeminal schwannoma of the sphenoid sinus--report of a rare entity. ( 24050208 )
2014
27
Trigeminal schwannoma extending into the parapharyngeal space. ( 24978683 )
2014
28
A large extra cranial cystic trigeminal schwannoma of the parapharyngeal space - exploring the right approach. ( 25419065 )
2014
29
Dumbbell-shaped primitive neuroectodermal tumor mimicking trigeminal schwannoma: a case report and review of literature. ( 23546917 )
2013
30
Large trigeminal schwannoma of the infratemporal fossa: evaluation of neoangiogenesis in this rare neoplasm. ( 22965871 )
2013
31
Abducens nerve palsy as the unique sign of a trigeminal schwannoma. ( 23031748 )
2013
32
Stereotactic radiosurgery for trigeminal schwannoma: a clinical retrospective study in 52 cases. ( 23548989 )
2013
33
Trigeminal schwannoma with extracranial extension and brainstem compression. ( 23632785 )
2013
34
Numb cheek syndrome: a clinical-anatomical correlation. Diagnosis: Trigeminal schwannoma. ( 24135951 )
2013
35
Clear cell meningioma masquerading as trigeminal schwannoma. ( 23050207 )
2012
36
Giant trigeminal schwannoma with parapharyngeal extension: report of a case. ( 21195625 )
2012
37
Combined craniofacial approach for the removal of a large trigeminal schwannoma invading the infratemporal fossa. ( 21842149 )
2012
38
Intraosseous trigeminal schwannoma of mandible with intracranial extension. ( 21269550 )
2011
39
Trigeminal schwannoma with intratumoral hemorrhage: report of a case and review of literature. ( 22019675 )
2011
40
Isolated lympho-histiocytic inflammation of the Gasserian ganglion mimicking trigeminal schwannoma. ( 20358510 )
2010
41
Surgery for a case of three-compartment trigeminal schwannoma : technical aspects. ( 21113372 )
2010
42
Dissemination of prostate adenocarcinoma to the skull base mimicking giant trigeminal schwannoma: anatomic relevance of the extradural neural axis component. ( 20436844 )
2009
43
Stereotactic radiosurgery for trigeminal schwannoma: tumor control and functional preservation Clinical article. ( 19301456 )
2009
44
Evolution in the assessment and management of trigeminal schwannoma. ( 18090871 )
2008
45
Brainstem compression from a trigeminal schwannoma presenting with pathological crying. ( 18191401 )
2008
46
A case of masticatory disturbance incidental to trigeminal schwannoma: changes in occlusal force and masticatory sensation before and after radiosurgery. ( 18270290 )
2008
47
Malignant trigeminal schwannoma extending into the anterior skull base. ( 18473115 )
2008
48
Multicompartmental trigeminal schwannoma--a clinical report. ( 18650756 )
2008
49
Giant dumbbell-shaped middle cranial fossa trigeminal schwannoma with extension to the infratemporal and posterior fossae. ( 17534571 )
2007
50
Gamma knife surgery for trigeminal schwannoma. ( 17542528 )
2007

Variations for Neurilemmoma of the Fifth Cranial Nerve

Expression for Neurilemmoma of the Fifth Cranial Nerve

Search GEO for disease gene expression data for Neurilemmoma of the Fifth Cranial Nerve.

Pathways for Neurilemmoma of the Fifth Cranial Nerve

Pathways related to Neurilemmoma of the Fifth Cranial Nerve according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 GFAP NF1 NF2 NUMB PRKAR1A

GO Terms for Neurilemmoma of the Fifth Cranial Nerve

Biological processes related to Neurilemmoma of the Fifth Cranial Nerve according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mesoderm formation GO:0001707 9.26 NF2 PRKAR1A
2 negative regulation of MAPK cascade GO:0043409 9.16 NF1 NF2
3 negative regulation of cell-matrix adhesion GO:0001953 8.96 NF1 NF2
4 negative regulation of protein kinase activity GO:0006469 8.92 NF1 NF2 PRKAR1A PTPRC

Sources for Neurilemmoma of the Fifth Cranial Nerve

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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