MCID: NRL001
MIFTS: 26

Neurilemmoma of the Fifth Cranial Nerve

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Neurilemmoma of the Fifth Cranial Nerve

MalaCards integrated aliases for Neurilemmoma of the Fifth Cranial Nerve:

Name: Neurilemmoma of the Fifth Cranial Nerve 12 15
Trigeminal Schwannoma 12 70
Trigeminal Neurilemmoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3202
NCIt 50 C4655
SNOMED-CT 67 277185000
UMLS 70 C0349582

Summaries for Neurilemmoma of the Fifth Cranial Nerve

MalaCards based summary : Neurilemmoma of the Fifth Cranial Nerve, also known as trigeminal schwannoma, is related to neurilemmoma and neuroma. An important gene associated with Neurilemmoma of the Fifth Cranial Nerve is NF2 (Neurofibromin 2), and among its related pathways/superpathways are Neuroscience and IL4-mediated signaling events. Affiliated tissues include trigeminal ganglion, bone and prostate, and related phenotype is homeostasis/metabolism.

Related Diseases for Neurilemmoma of the Fifth Cranial Nerve

Diseases related to Neurilemmoma of the Fifth Cranial Nerve via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 neurilemmoma 30.1 NF2 NF1 LZTR1
2 neuroma 29.9 NF2 NF1
3 neurofibroma 29.9 NF2 NF1
4 cellular schwannoma 29.9 NF2 NF1
5 obstructive hydrocephalus 29.8 NF2 NF1
6 acoustic neuroma 29.8 NF2 NF1 LZTR1
7 trigeminal neuralgia 10.3
8 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.2
9 ataxia and polyneuropathy, adult-onset 10.2
10 neurofibromatosis 10.2
11 rare tumor 10.2
12 intraorbital meningioma 10.1 NF2 LZTR1
13 olfactory groove meningioma 10.1 NF2 LZTR1
14 anterior cranial fossa meningioma 10.1 NF2 LZTR1
15 meningioma, familial 10.1
16 intracranial meningioma 10.1
17 hydrocephalus 10.1
18 secretory meningioma 10.1
19 lymphoplasmacyte-rich meningioma 10.1
20 b-cell lymphoma 10.1
21 schwannomatosis 1 10.1 NF2 LZTR1
22 meninges hemangiopericytoma 10.1 STAT6 NF2
23 epithelioid neurofibroma 10.1 NF2 NF1
24 cerebral falx meningioma 10.0 NF2 NF1
25 plexiform schwannoma 10.0 NF2 NF1
26 small intestine leiomyoma 10.0 NF2 NF1
27 abducens palsy 10.0
28 chordoma 10.0
29 diffuse large b-cell lymphoma 10.0
30 lymphoma 10.0
31 abducens nerve disease 10.0
32 cranial nerve palsy 10.0
33 exophthalmos 10.0
34 paresthesia 10.0
35 polyp of corpus uteri 10.0 NF2 NF1
36 schwannoma of twelfth cranial nerve 10.0 NF2 NF1
37 hypoglossal nerve disease 10.0 NF2 NF1
38 adult malignant schwannoma 10.0 NF2 NF1
39 orbital cancer 10.0 NF2 NF1
40 corpus callosum lipoma 10.0 NF2 NF1
41 cerebral hemisphere lipoma 10.0 NF2 NF1
42 rete ovarii adenoma 10.0 NF2 NF1
43 rete ovarii benign neoplasm 10.0 NF2 NF1
44 optic nerve glioma 10.0 NF2 NF1
45 neurofibrosarcoma 10.0 NF2 NF1
46 benign ependymoma 10.0 NF2 NF1
47 lipomatosis, multiple 10.0
48 pleomorphic lipoma 10.0
49 plexiform neurofibroma 10.0 NF2 NF1
50 sturge-weber syndrome 10.0 NF2 NF1

Graphical network of the top 20 diseases related to Neurilemmoma of the Fifth Cranial Nerve:



Diseases related to Neurilemmoma of the Fifth Cranial Nerve

Symptoms & Phenotypes for Neurilemmoma of the Fifth Cranial Nerve

MGI Mouse Phenotypes related to Neurilemmoma of the Fifth Cranial Nerve:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.17 LZTR1 NF1 NF2 NTSR1 NUMB STAT6

Drugs & Therapeutics for Neurilemmoma of the Fifth Cranial Nerve

Search Clinical Trials , NIH Clinical Center for Neurilemmoma of the Fifth Cranial Nerve

Genetic Tests for Neurilemmoma of the Fifth Cranial Nerve

Anatomical Context for Neurilemmoma of the Fifth Cranial Nerve

MalaCards organs/tissues related to Neurilemmoma of the Fifth Cranial Nerve:

40
Trigeminal Ganglion, Bone, Prostate

Publications for Neurilemmoma of the Fifth Cranial Nerve

Articles related to Neurilemmoma of the Fifth Cranial Nerve:

(show top 50) (show all 198)
# Title Authors PMID Year
1
Surgical Outcome of Trigeminal Schwannomas. 61
33804067 2021
2
The Zap-X Radiosurgical System in the Treatment of Intracranial Tumors: A Technical Case Report. 61
33442727 2021
3
Commentary: Double-Stage Complete Removal of Dumbbell-Shaped Trigeminal Schwannoma: 3-Dimensional Operative Video. 61
33763688 2021
4
Double-Stage Complete Removal of Dumbbell-Shaped Trigeminal Schwannoma: 3-Dimensional Operative Video. 61
33733671 2021
5
Combined Petrosal Approach for Resection of a Large Trigeminal Schwannoma With Meckel's Cave Involvement-Part I: Anatomic Rationale and Analysis: 2-Dimensional Operative Video. 61
33294932 2021
6
Combined Petrosal Approach for Resection of a Large Trigeminal Schwannoma With Meckel's Cave Involvement-Part II: Microsurgical Approach and Tumor Resection: 2-Dimensional Operative Video. 61
33300040 2021
7
Neurocysticercosis Superimposing Schwannoma: A Unique Combination of 2 Pathologies at Cerebellopontine Cistern. 61
33342760 2021
8
Epidermoid Cyst Extending Along Trigeminal Nerve Pathway with Unusual Imaging Findings. 61
33144211 2021
9
Trigeminal schwannoma: a single-center experience with 43 cases and review of literature. 61
32628557 2021
10
Commentary: Anterior Petrosal Approach for Enlarging Previously Radiated Recurrent Trigeminal Schwannoma: 2-Dimensional Operative Video. 61
33428760 2021
11
Anterior Petrosal Approach for Enlarging Previously Radiated Recurrent Trigeminal Schwannoma: 2-Dimensional Operative Video. 61
33438028 2021
12
Intraoperative Neurophysiological Monitoring During Trigeminal Schwannoma Surgery. 61
33042663 2020
13
Expanded Endonasal Approach for Resection of Extradural Infratemporal Fossa Trigeminal Schwannoma: 2-Dimensional Operative Video. 61
32348506 2020
14
Endoscope-Assisted Retromastoid Intradural Suprameatal Approach for Trigeminal Schwannoma. 61
33109844 2020
15
Image-guided endonasal endoscopic excision of Meckel's cave trigeminal schwannoma from cavernous and petrous carotid artery. 61
33024535 2020
16
The Importance of STAT6 in a Schwannoma-like Grade III Solitary Fibrous Tumor/Hemangiopericytoma Located in the Cerebellopontine Angle and Meckel's Cave. 61
32526357 2020
17
Use of endoscopic transorbital and endonasal approaches for 360° circumferential access to orbital tumors. 61
32977310 2020
18
Intracranial emergencies during pregnancy requiring urgent neurosurgical treatment. 61
32428795 2020
19
[Progress in the surgical treatment of trigeminal schwannoma]. 61
32727200 2020
20
Surgical Management of Multifocal Trigeminal Schwannomas. 61
32717071 2020
21
A Trigeminal Schwannoma Masked by Solely Vestibulocochlear Symptoms. 61
31758677 2020
22
In Reply to the Letter to the Editor Regarding "Resection of Pediatric Trigeminal Schwannoma Using Minimally Invasive Approach: Case Report, Literature Review and Operative Video". 61
32059290 2020
23
Letter to the Editor Regarding "Resection of Pediatric Trigeminal Schwannoma Using Minimally Invasive Approach: Case Report, Literature Review, and Operative Video". 61
32059289 2020
24
Disuse atrophy of masticatory muscles after intracranial trigeminal schwannoma resection: A case report and review of literature. 61
32937220 2020
25
Trigeminal schwannoma presenting with malocclusion: A case report and review of the literature. 61
32874733 2020
26
Ancient Schwannoma affecting the intracranial portion of the trigeminal nerve: A case report. 61
33365188 2020
27
Anterior Transpetrosal Approach for Trigeminal Schwannoma with Persistent Primitive Trigeminal Artery: 2-Dimensional Operative Video. 61
30873527 2019
28
Letter to the Editor Regarding "Resection of Pediatric Trigeminal Schwannoma Using Minimally Invasive Approach: Case Report, Literature Review, and Video Submission". 61
31658558 2019
29
Letter to the Editor Regarding "Resection of Pediatric Trigeminal Schwannoma Using Minimally Invasive Approach: Case Report, Literature Review, and Operative Video". 61
31658560 2019
30
In Reply to the Letter to the Editor Regarding "Resection of Pediatric Trigeminal Schwannoma Using Minimally Invasive Approach: Case Report, Literature Review, and Video Submission". 61
31658561 2019
31
Commentary: Anterior Transpetrosal Approach for Trigeminal Schwannoma With Persistent Primitive Trigeminal Artery: 2-Dimensional Operative Video. 61
31131851 2019
32
Letter to the Editor Regarding "Resection of Pediatric Trigeminal Schwannoma Using Minimally Invasive Approach: Case Report, Literature Review, and Video Submission". 61
31581397 2019
33
In Reply to "Pediatric Trigeminal Schwannoma: From a 'Minimally Invasive' to a Combined Endovascular and Surgical Management". 61
31581398 2019
34
Skull Base Manifestations of Erdheim-Chester Disease: A Case Series and Systematic Review. 61
30828728 2019
35
Granular cell tumour of the cavernous sinus: A rare cause of secondary trigeminal neuralgia. 61
31650863 2019
36
In Reply to 'Pediatric Trigeminal Schwannoma: From a "Minimally Invasive" to a Combined Endovascular and Surgical Management'. 61
31426265 2019
37
Pediatric Trigeminal Schwannoma: From a "Minimally Invasive" to a Combined Endovascular and Surgical Management. 61
31426264 2019
38
Trigeminal Ganglion Metastasis of Renal Clear Cell Carcinoma: Cases Report and Review of the Literature. 61
31059855 2019
39
Resection of Pediatric Trigeminal Schwannoma Using Minimally Invasive Approach: Case Report, Literature Review, and Operative Video. 61
31009782 2019
40
Middle Fossa Approach With Anterior Petrosectomy for Resection of a Meningioma Mimicking a Trigeminal Schwannoma, a Step-by-Step Surgical and Anatomical Description: 2-Dimensional Operative Video. 61
31197348 2019
41
Renal Cell Carcinoma with Primary Presentation via Metastasis to the Trigeminal Ganglion. 61
30844522 2019
42
Microsurgical Management of Trigeminal Schwannoma: Cohort Analysis and Systematic Review. 61
31143569 2019
43
Diffuse Large B Cell Lymphoma Presented as Trigeminal Neuralgia: 2 Cases Reported and Literature Review. 61
30528527 2019
44
Endoscopic Two-port Technique for Infratemporal Fossa Tumors: Using Prelacrimal Medial Maxillectomy and Caldwell-Luc Approach. 61
30611951 2019
45
Nonvestibular Schwannoma Tumors in the Cerebellopontine Angle: A Single-Surgeon Experience. 61
30937027 2019
46
Presigmoid Approach to Dumbbell Trigeminal Schwannoma. 61
30456036 2018
47
Retrosigmoid Approach to the Posterior Fossa Trigeminal Schwannoma. 61
30456037 2018
48
Trigeminal Nerve Schwannoma of the Cerebellopontine Angle. 61
30456035 2018
49
Neuroendoscopic Resection of Trigeminal Schwannoma in the Pterygopalatine/Infratemporal Fossa via the Transnasal Perpendicular Plate Palatine Bone or Transnasal Maxillary Sinus Approach. 61
30218796 2018
50
Endoscopic transorbital surgery for Meckel's cave and middle cranial fossa tumors: surgical technique and early results. 61
30544350 2018

Variations for Neurilemmoma of the Fifth Cranial Nerve

Expression for Neurilemmoma of the Fifth Cranial Nerve

Search GEO for disease gene expression data for Neurilemmoma of the Fifth Cranial Nerve.

Pathways for Neurilemmoma of the Fifth Cranial Nerve

Pathways related to Neurilemmoma of the Fifth Cranial Nerve according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 NUMB NF2 NF1
2 10.76 TFF3 STAT6

GO Terms for Neurilemmoma of the Fifth Cranial Nerve

Cellular components related to Neurilemmoma of the Fifth Cranial Nerve according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical part of cell GO:0045177 8.62 NUMB NF2

Biological processes related to Neurilemmoma of the Fifth Cranial Nerve according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of protein kinase activity GO:0006469 8.96 NF2 NF1
2 negative regulation of MAPK cascade GO:0043409 8.62 NF2 NF1

Sources for Neurilemmoma of the Fifth Cranial Nerve

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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